Clinical trials: Arthritis Knee
Osteo Arthritis Knee and Hip
Test-Retest Reliability of a Submaximal Exercise Test in Patients With Hip and Knee Osteoarthritis
The aim is to evaluate the test-retest reliability of the primary care-adapted Ekblom-Bak submaximal ergometer bicycle test in patients with hip- and/or knee osteoarthritis (OA).
- Trial name
- NCT07383740
- Testing
- Submaximal cycle ergometer test-retest
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Knee Arthritis Osteoarthritis, Platelet Rich Plasma Injection
Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS)
The effects of single dose injection of platelet rich plasma or conditioned serum in the knee joint in patients with knee osteoarthritis will be compared
- Conditions
- Knee Arthritis Osteoarthritis, Platelet Rich Plasma Injection, Conditioned Serum
- Trial name
- KOA PRP ACS (NCT07473232)
- Testing
- Autologous Platelet-Rich Plasma (PRP), Conditioned serum (CS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Osteo Arthritis Knee, Knee Pain Chronic
Optimizing Pain Self-Management in Total Knee Arthroplasty
The purpose of this study is to investigate the efficacy of a positive affect enhancing intervention designed to reduce pain and augment reward system function in knee osteoarthritis (KOA) patients undergoing total knee…
- Conditions
- Osteo Arthritis Knee, Knee Pain Chronic, Surgery
- Trial name
- NCT06038240
- Testing
- Savoring Meditation, Pain Self-Management and Education
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Virginia
Arthritis Knee
Functional Recovery After Total Knee Arthroplasty
The goal of this observational study is to learn about patients' recoveries after receiving total knee arthroplasty (TKA). The main questions it aims to answer are: Does robotic-assisted TKA have improved perceived recovery when…
- Trial name
- NCT06821269
- Testing
- Robotic assisted total knee arthroplasty, Manual total knee arthroplasty, Robotic assisted revision total knee arthroplasty
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Knee Arthritis Osteoarthritis
Effects of Motivational Interviewing on Pain Self-Efficacy and Exercise Behavior in Individuals With Knee Osteoarthritis
This randomized controlled trial aims to investigate the effects of motivational interviewing added to a neuromuscular exercise and home exercise program on pain self-efficacy, exercise behavior, pain intensity, physical…
- Trial name
- NCT07767812
- Testing
- Motivational Interviewing, Neuromuscular Exercise Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Kutahya Health Sciences University
Osteo Arthritis of the Knee
Minimal-Incision Technique With Modified Tracking Pin Placement Versus Standard Robotic-Assisted Total Knee Arthroplasty
This randomized controlled trial will compare a minimal-incision and soft-tissue-preserving (MISI) technique with the standard surgical technique in patients undergoing robotic-assisted total knee arthroplasty for knee…
- Trial name
- MISI (NCT07765771)
- Testing
- MISI Robot-Assisted Total Knee Arthroplasty, Standard Robotic-Assisted Total Knee Arthroplasty
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Osteo Arthritis Knee, Pain, Postoperative
Extended Oral Tranexamic Acid After Total Knee Arthroplasty
The utilization of intraoperative tranexamic acid (TXA), whether administered intravenously or orally, has become a standard practice in total joint arthroplasty (TJA).
- Trial name
- NCT06618820
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Campbell Clinic
Osteoarthritis (OA) of the Knee, Knee Pain Arthritis
Imageless Navigation Versus Image-Based Navigation in Robotic-Assisted Total Knee Arthroplasty for Knee Osteoarthritis
The goal of this clinical trial is to learn if imageless navigation is not inferior to image-based navigation in robotic-assisted total knee arthroplasty (RA-TKA) for treating patients with knee osteoarthritis.
- Conditions
- Osteoarthritis (OA) of the Knee, Knee Pain Arthritis, Total Knee Arthroplasty (TKA), Robotic Assisted Arthroplasty
- Trial name
- NCT07522489
- Testing
- Imageless Robotic-Assisted Total Knee Arthroplasty, Image-based Robotic-Assisted Total Knee Arthroplasty
- Where
- Poland
- Volunteers
- 146 people
- Sponsor
- Medical University of Warsaw
Knee Arthritis Osteoarthritis, Knee Replacement Arthroplasty
Is BMI Outdated in TKA Patient Selection? Assessment of the Impact of Pre-tubercular Subcutaneous Tissue Thickness and the Risk of Postoperative Infection Following Total Knee Arthroplasty
While Body Mass Index (BMI) is currently used as a primary tool for risk stratification in patients undergoing Total Knee Athroplasty(TKA), its limitations raise concerns regarding its accuracy and fairness in guiding surgical…
- Conditions
- Knee Arthritis Osteoarthritis, Knee Replacement Arthroplasty, BMI, Regional Body Composition
- Trial name
- BEYOND-BMI (NCT07763535)
- Volunteers
- 400 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Low Back Pain, Knee Arthritis Osteoarthritis
How Patient Education Helps Patients With Chronic Musculoskeletal Disorders Stick to Home Exercise for Pain Relief.
The study aims to evaluate the effectiveness of a structured patient education program in enhancing adherence to prescribed home exercise regimens in individuals with chronic low back pain, knee osteoarthritis, and shoulder pain.
- Conditions
- Low Back Pain, Knee Arthritis Osteoarthritis, Shoulder Disease, Shoulder and Upper Arm Injury
- Trial name
- NCT07764354
- Testing
- Educational with musculoskeletal condition, Standard physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Knee Arthritis, Osteoarthritis
Eccentric vs Low-Load Blood Flow Restriction Training in Knee Osteoarthritis in Knee Osteoarthritis
The aim of this randomized controlled trial is to find the effects of eccentric and low-load blood flow restriction training on neuromuscular adaptations, muscle strength, functional performance, and disability in patients with…
- Trial name
- the (NCT07733518)
- Testing
- Eccentric Gastrocnemius Strengthening Exercises, Low-Load Blood Flow Restriction Training
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Inflammatory Arthritis, Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis)
A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)
The purpose of this study is to assess the long-term safety and performance of the LEGION Medial Stabilized insert and to generate clinical evidence to support and maintain product registration in global markets.
- Conditions
- Inflammatory Arthritis, Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis), Post-traumatic Arthritis
- Trial name
- NCT07199738
- Testing
- Cemented CoCr, Cemented Oxinium, Cementless
- Where
- 4 sites in United States
- Volunteers
- 144 people
- Sponsor
- Smith & Nephew, Inc.
Spine Degeneration, Hip Arthritis
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
This study aims to evaluate the effectiveness of a mobile application in improving postoperative rehabilitation outcomes among patients undergoing orthopedic surgery.
- Conditions
- Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
- Trial name
- NCT06407427
- Testing
- App for in-bed conditioning exercises, Usual care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Knee Arthritis Osteoarthritis
Effects of Various Types of Ultrasound Therapy in Knee Osteoarthritis
Knee osteoarthritis (KOA) is a degenerative joint condition characterized by degeneration, which is commonly attributed to the cumulative effects of mechanical stress and the slow deterioration of articular cartilage.
- Trial name
- NCT07738692
- Testing
- Metfomin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Horus University
Osteo Arthritis of the Knee
Research Title: Long Term Functional Outcome of a Single Hyaluronic Acid Injection in Improving Symptoms and Function in Patients With Knee Osteoarthritis - A Single-Arm Open-Label Study (DIART ONE).
This study aims to evaluate the effectiveness of a single HA injection in improving pain, function, and quality of life in patients with knee OA over a 12-month period.
- Trial name
- NCT07736781
- Testing
- Hyaluronic Acid (HA)
- Where
- Malaysia
- Volunteers
- 62 people
- Sponsor
- Universiti Sains Malaysia
Knee Osteoarthritis (Knee OA), Knee Arthritis, Osteoarthritis
Effects of Pressure Biofeedback Training Versus Bolster Foam Roll Training for Pain, Muscles Activation, and Quality of Life Among Knee Osteoarthritis Patients
The current study will be a single-blinded, two-arm parallel group randomized clinical trial involving 48 participants. The trial will compare Pressure Biofeedback training with Bolster Foam Roll training.
- Trial name
- NCT07731737
- Testing
- pressure Biofeedback Training, Bolster Foam Roll Training
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Knee Osteoarthritis
A Powered Exoskeleton for Veterans With Knee OA
The purpose of this study is to evaluate in-laboratory mobility outcomes, pain perception, and user satisfaction with the Keeogo , a robotic exoskeleton for providing assistance on knees during stand and swing for a population…
- Trial name
- NCT04653896
- Testing
- Keeogo
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- VA Office of Research and Development
Arthritis (Knee), Varus Knee
Precision of Pacient-specific Instrumented Open Wedge High Tibial Osteotomy vs Conventional Technicque
This study is a randomized clinical trial that will compare two surgical techniques for patients with knee osteoarthritis and varus deformity who are candidates for medial opening wedge high tibial osteotomy.
- Trial name
- AMBE_OR (NCT07212777)
- Testing
- Medial Open Wedge Hight Tibial Osteotomy using patient-specific instrumentation, Medial Open Wedge Hight Tibial Osteotomy using conventional surgery techniques
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Malaga
Osteo Arthritis Knee
Multimodal Treatment of Knee Osteoarthritis: Therapeutic Exercise and Noninvasive Neuromodulation (NESA) Versus Therapeutic Exercise and Transcutaneous Electrical Nerve Stimulation (TENS) in People Over 60 Years of Age.
To analyze the effects of therapeutic exercise combined with noninvasive neuromodulation (NESA) or transcutaneous electrical nerve stimulation (TENS) on improving clinical symptoms such as joint pain and stiffness, as well as its…
- Trial name
- NCT07258693
- Testing
- Therapeutic exercise and NESA VS. Therapeutic exercise and TENS
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- University of Jaén
Knee Injuries, Knee Osteoarthritis
Blood-Flow Restriction Exercise Following a Knee Replacement
This study will determine the safety and efficacy of using blood-flow restriction exercise enhancement (B-FREE) to overcome persistent quadriceps muscle weakness that occurs following a total knee replacement (TKR).
- Conditions
- Knee Injuries, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT04018638
- Testing
- B-FREE
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Michigan Technological University