Clinical trials: Arthritis of Knee
Osteoarthritis, Articular Cartilage
Effects of Anthriscus Sylvestris Leaves on Mild Knee Osteoarthritis
Osteoarthritis (OA) is a common degenerative joint disorder that causes pain, stiffness, and functional impairment. Current treatments for OA are limited to symptom relief and have potential side effects.
- Conditions
- Osteoarthritis, Articular Cartilage, Functional Food
- Trial name
- NCT06535204
- Testing
- Aqueous extract of A. sylvestris leaves, microcrystalline cellulose
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Osteoarthritis, Total Knee Replacement
Static and Dynamic Balance in Correlation With Quality of Life, in Primary Total Knee Replacement
Knee osteoarthritis (OA) is one of the most prevalent musculoskeletal complaints worldwide, affecting 30-40% of the population by the age of 65 yr.Individuals with knee OA suffer progressive loss of function.Balance is an…
- Trial name
- NCT00256958
- Testing
- total knee replacement
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Hadassah Medical Organization
Bilateral Primary Osteoarthritis of Knee
Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis
The overall goal of this study is to develop regenerative cell therapy for use in patients with osteoarthritis (OA). The primary objective of this proposal is to conduct a pilot study that assesses the safety and feasibility of…
- Trial name
- BMAC (NCT01931007)
- Testing
- Autologous Bone Marrow Aspirate Concentrate, Sterile saline
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoarthritis of the Knee
Preparation Rich in Growth Factors (PRGF) Treatment for Osteoarthritis of the Knee
to evaluate the influence of PRGF treatment on patient suffering from OA knee
- Trial name
- NCT00728611
- Testing
- PRGF, hyaluronic acid
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Osteoarthritis, Sedentary
Swedish PAP in Osteoarthritis - a RCT Study
The purpose of this study is to determine whether an intervention with Physical activity on prescription (PAP) to individuals in primary care with knee or hip osteoarthritis would result in effects on physical activity level…
- Trial name
- NCT02387034
- Testing
- Physical activity on prescription, General advice
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Uppsala University
Knee Osteoarthritis
Navigation System for in Vivo Measurement of the Kinematics of the Knee
The knee prosthesis is a validated treatment for end-stage osteoarthritis, and this intervention usually provides a significant improvement in the quality of life of patients.
- Trial name
- NCT02467699
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Osteoarthritis Of Knee
Trial to Assess the Structural Effect and Long-term Symptomatic Relief of Intra-articular Injections of Hyaluronic Acid in Primary Knee OA
The present study is designed to test the hypothesis that Intra-Articular Hyaluronic Acid (IAHA) is superior to placebo in slowing structural progression and on long term symptomatic effect in primary knee Osteoarthritis (OA)…
- Trial name
- ViscOA (NCT02280538)
- Testing
- Intra-Articular Hyaluronic Acid
- Where
- 2 sites in Portugal
- Volunteers
- 300 people
- Sponsor
- Universidade Nova de Lisboa
Chronic Pain, Lumbar Back Pain
Effectiveness of Acupuncture Clinical Pathway
The study will be described the development and implementation of the Clinical pathway (CPW) for acupuncture treatment in the management of patients with some chronic pain conditions.
- Conditions
- Chronic Pain, Lumbar Back Pain, Osteoarthritis, Knee, Headache
- Trial name
- ACUPATHWAY (NCT04490798)
- Testing
- Electroacupuncture
- Where
- Spain
- Volunteers
- 3,245 people
- Sponsor
- Hospital Son Llatzer
Arthroplasty, Replacement, Knee, Knee Osteoarthritis
Smart Kneebrace for Continuous Monitoring of Joint Angles During Rehabilitation
This study aims to investigate the effect of Smart Kneebrace use for osteoarthritis patients after total knee arhtroplasty (TKA) on post-operative performance.
- Trial name
- NCT03365284
- Testing
- Smart Kneebrace with a smart phone app, regular rehabilitation procedure
- Volunteers
- 60 people
- Sponsor
- Peking University People's Hospital
Knee Osteoarthristis
Medication vs. Meditation for Chronic Knee Osteoarthritis
The purpose of this research study is to improve pain management for individuals with chronic knee osteoarthritis pain. Specifically, we are comparing the effects of a mindfulness meditation practice with those of oral…
- Trial name
- NCT07837284
- Testing
- Oral diclofenac potassium 50 mg, Mindfulness meditation
- Volunteers
- 30 people
- Sponsor
- Florida State University
Knee Osteoarthritis
The Effect of Corrective Osteotomy on in Vivo Cartilage Mechanobiology in Patients With Knee Osteoarthritis
Our overall hypothesis is that a sudden ambulatory load reduction (caused by corrective osteotomy) leads to changes in cartilage biology that delay or reverse osteoarthritic processes determining the clinical outcome and…
- Trial name
- Osteotomy (NCT02622204)
- Testing
- Corrective osteotomy
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University Hospital, Basel, Switzerland
Osteoarthritis
Efficacy of Proprietary Cherry Juice Blend in Osteoarthritis of the Knee
The primary purpose of this research study is to test the ability of a proprietary cherry juice blend to be helpful in the treatment of osteoarthritis (OA) of the knee.
- Trial name
- NCT00443092
- Testing
- proprietary cherry juice blend (food), control juice (kool aid blend)
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- CherryPharm
Osteoarthritis, Knee
Parabens Flocculation on the Anti Inflammatory Effects of Corticosteroid Injections for Total Knee Arthroplasty
The purpose of this study is to identify whether corticosteroid use with anesthetics containing preservatives (parabens) reduces clinical effectiveness of the anti-inflammatory agent Up to 100 patients, both male and female…
- Trial name
- 5160373 (NCT03445611)
- Testing
- corticosteroid solution with lidocaine containing parabens., corticosteroid solution with lidocaine containing no paraben
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Osteoarthritis
Tanezumab in Osteoarthritis of the Hip or Knee (2)
Test the efficacy and safety of 2 doses of tanezumab compared with naproxen and placebo in patients with osteoarthritis
- Trial name
- NCT00863304
- Testing
- tanezumab 10 mg, tanezumab 5 mg, naproxen
- Where
- 95 sites in United States
- Volunteers
- 849 people
- Sponsor
- Pfizer
Pain Associated With Osteoarthritis of the Knee
A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis Knee Pain
This is a Phase 3, Multicenter, 22-Week, double-blind and 30-Week open label Study to Evaluate the Efficacy and Safety of X0002 Spray in relief of pain of subjects with Osteoarthritis of the Knee.
- Trial name
- NCT03081806
- Testing
- X0002
- Where
- 33 sites in United States
- Volunteers
- 399 people
- Sponsor
- Techfields Pharma Co. Ltd
Knee Osteoarthritis
Impact of Volunteerism in the Acute Setting
Rehabilitation, with a particular emphasis on physiotherapy and exercise, is widely promoted and strongly recommended after total knee replacement (TKR).
- Trial name
- NCT04063553
- Testing
- Volunteers Service, Exercise brochure
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Tan Tock Seng Hospital
Knee Osteoarthritis
Effects of KT and Rigid Taping in Knee OA.
The purpose of the study is to compare the effects of kinesio taping and rigid taping in Knee Osteoarthritis to alleviate symptoms like pain, reduce range of motion and functional limitations.
- Trial name
- NCT05946434
- Testing
- Kinesio Tape Group, Rigid Tape Group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Osteoarthritis, Knee
Clinical Outcomes of MP Persona vs. Persona Knee-PS
Knee osteoarthritis (OA) is a highly prevalent condition that results in substantial pain and loss of function. The end stage treatment for knee OA is total knee arthroplasty (TKA), a common and safe procedure typically performed…
- Trial name
- MP-Persona (NCT03681977)
- Testing
- Zimmer MP Persona, Zimmer Persona Knee-PS
- Where
- 3 sites in Canada
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Osteoarthritis
A Study to Evaluate the Effect of Analgesics on a Walking Model of Knee Pain (0000-105)(COMPLETED)
This study will evaluate a walking model of osteoarthritis for use in testing of new therapeutic agents. The primary hypothesis is that participants treated with Naproxen or Ultracet will have lower Pain Intensity (PI) than those…
- Trial name
- NCT00772967
- Testing
- Naproxen, Ultracet
- Volunteers
- 22 people
- Sponsor
- Merck Sharp & Dohme LLC
Osteoarthritis, Knee
A Phase 1/2A, Single Dose Study Of PF-04383119 In Japanese Patients With Moderate To Severe Pain From Osteoarthritis Of The Knee
To evaluate the safety and tolerability of single IV doses of PF-04383119 in Japanese patients with moderate to severe pain from OA of the knee (Part I).
- Trial name
- NCT00669409
- Testing
- PF-04383119 (tanezumab)
- Where
- 12 sites in Japan
- Volunteers
- 83 people
- Sponsor
- Pfizer