Clinical trials: Arthropathy of Knee
Knee Osteoarthritis, Sarcopenia
The Effects of Pulsed Electromagnetic Field Therapy on Patients With End-stage of Knee Osteoarthritis
A double-blinded, randomizepd controlled trial to investigate the treatment effects of pulsed electromagnetic field (PEMF) on end stage of knee osteoarthritis patients with sarcopenia will be carried out.
- Trial name
- NCT05550428
- Testing
- home-based-exercise, active pulsed electromagnetic field（PEMF）therapy
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Extended Post-operative Oral TXA in Primary THA
The goal of this clinical trial is to learn if extended post-operative oral tranexamic acid (TXA) - a medication that reduces bleeding by slowing the breakdown of blood clots - can improve functional recovery following surgery in…
- Trial name
- NCT07685743
- Testing
- Extended oral tranexamic acid regimen
- Volunteers
- 170 people
- Sponsor
- Oregon Health and Science University
Pain, Postoperative, Osteoarthritis, Knee
Analgesic Efficacy of Pre-operative Dose of Ketorolac and Gabapentin
Evaluation of the analgesic efficacy of a pre-operative dose of ketorolac and gabapentin in reducing post-operative pain scores in patients undergoing TKA
- Trial name
- NCT07047040
- Testing
- Ketorolac Tromethamine 30 MG/ML Prefilled Syringe, Gabapentin, Empty Medication Capsules
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Assiut University
Metabolic Syndrome, Osteoarthritis, Hip
Effects of a Clinical Dietary Intervention During Inpatient Treatment
The purpose of the study is a scientific and prospective documentation of the clinical effects of an inpatient treatment at the Immanuel Hospital of Berlin, in the department for complementary and integrative medicine, with the…
- Conditions
- Metabolic Syndrome, Osteoarthritis, Hip, Osteoarthritis, Knee, Rheumatoid Arthritis
- Trial name
- FASTA (NCT03785197)
- Testing
- Prolonged modified fasting
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Charite University, Berlin, Germany
Osteoarthritis, Knee, Postoperative Pain
A Randomized Comparison of the Efficacy of the IPACK Block Versus the Popliteal Plexus Block for Posterior Knee Analgesia, in Patients Undergoing a Total Knee Arthroplasty and Receiving a Continuous Distal Femoral Triangle Block
Total knee arthroplasty (TKA) is commonly associated with significant postoperative pain, including pain arising from the posterior aspect of the knee.
- Trial name
- NCT07876310
- Testing
- Ultrasound-Guided iPACK Block, Ultrasound-Guided Popliteal Plexus Block, Ultrasound-Guided Continuous Femoral Triangle Block
- Volunteers
- 136 people
- Sponsor
- Clinica Santa Maria
Healthy
The Effect of Estrogen and Progesterone Levels on Knee and Ankle Joint Laxity
The proposed research is an observational study designed to compare estrogen and progesterone serum levels with knee and ankle joint laxity, and muscle reaction time as a measure of neuromuscular function.
- Trial name
- NCT00005923
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Osteoarthritis
Kinematic Analysis of a PS, FB Primary Total Knee Arthroplasty (ATTUNE Knee System) Using Dynamic RSA
Background: Across the European Union there are 535,000 Total Knee Arthroplasty (TKA)per year. Statistics indicate that for patients over 60 year old approximately one out of 20 will require corrective reoperations within 10…
- Trial name
- Attune-RSA (NCT02323386)
- Testing
- Primary Total Knee Arthroplasty (ATTUNE Knee System)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis of Knee
Effect of Overdose Ultrasound on Osteoarthritic Knee in Adult Albino Rat: a Histological Study
The purpose of this study is to investigate the effect of overdose ultrasound on the articular cartilage of the osteoarthritic knee in adult albino rate.
- Trial name
- NCT06774469
- Testing
- assigned, Injection, Solution, ultrasound
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoarthritis of the Knee
Hydros and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis
The purpose of this study is to evaluate the safety and efficacy of Hydros-TA Joint Therapy for relief of pain due to OA of the knee.
- Trial name
- NCT02022930
- Testing
- Hydros, Hydros-TA, Triamcinolone Acetonide
- Where
- 5 sites in Australia, Canada and 1 more
- Volunteers
- 510 people
- Sponsor
- Carbylan Therapeutics, Inc.
Osteoarthritis
Application of Radiostereometric Analysis (RSA) to Triathlon Knee Components Inserted Using the OtisMed Custom-fit Total Knee Replacement System
The OtisMed Custom-fit system for total knee replacements replaces conventional surgical techniques for templating and intra-operative instrumentation with a preoperative virtual surgery process that utilizes 3D models of the…
- Trial name
- NCT01262430
- Testing
- OtisMed, Computer Assisted Surgery (CAS)
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Dalhousie University
Medial Compartment Knee Osteoarthritis
Effects of Lateral Wedge Insoles, Knee Taping on the Management of Knee Osteoarthritis
Knee osteoarthritis (OA) is a degenerative, progressive and wide spread disease, which may lead the patient to severe outcomes e.g. pain, loss of joint motion, inflexibility, disability and decreases the quality of life (QOL).
- Trial name
- NCT03848130
- Testing
- Mulligan Knee Taping with Home Exercises, Lateral wedge insoles with Home Exercises, Traditional Physiotherapy with Home Exercises
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Isra University
Knee Osteoarthrosis
Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis
Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT06937528
- Testing
- Extracellular vesicles
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- University of Jordan
Joint Pain, Knee Osteoarthritis
Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute Exacerbation
This is a Phase III, longitudinal, multicenter, randomized, double-blind clinical trial designed to evaluate the efficacy and safety of a fixed-dose combination of celecoxib and acetaminophen compared to celecoxib monotherapy for…
- Conditions
- Joint Pain, Knee Osteoarthritis, Hip Osteoarthritis
- Trial name
- PRECEDENT (NCT06863636)
- Testing
- Celecoxib + Acetaminophen, Celecoxib
- Where
- Mexico
- Volunteers
- 231 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Osteoarthritis, Pain, Postoperative
Liposomal Bupivacaine Versus Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Total Knee Arthroplasty
The purpose of this study is to compare the efficacy and duration of pain relief after total knee arthroplasty provided by a single injection of liposomal bupivacaine (EXPAREL®) versus standard bupivacaine with an adjuvant…
- Trial name
- NCT02624856
- Testing
- Liposomal bupivacaine, Bupivacaine plus dexamethasone
- Where
- United States
- Sponsor
- Albany Medical College
Osteoarthritis of the Knee
Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis
The study will identify the efficacy of Apitox, purified honeybee toxin, in 330 patients with diagnosed osteoarthritis of the knee.
- Trial name
- NCT01112722
- Testing
- Apitox, purified honeybee toxin, lyophilized in saline, histamine
- Where
- 15 sites in United States
- Volunteers
- 363 people
- Sponsor
- Apimeds, Inc.
Osteoarthritis
The Effectiveness of Strength Training and Self-management in Reducing Symptoms for Individuals With Knee Osteoarthritis
This study aims to investigate the effectiveness of an intervention combining strength training and self-management education in improving symptoms, sleep quality, emotional well-being, and quality of life in patients with knee…
- Trial name
- NCT07804212
- Testing
- Strength Training
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Pingtung Veterans General Hospital
Osteoarthritis, Knee
Use of Senolytic and Anti-Fibrotic Agents to Improve the Beneficial Effect of Bone Marrow Stem Cells for Osteoarthritis
This is a prospective, randomized, double-blind, active control clinical trial to evaluate the safety and efficacy of a senolytic agent (Fisetin) and an anti-fibrotic agent (Losartan), used independently and in combination, to…
- Trial name
- NCT04815902
- Testing
- Fisetin, Losartan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Steadman Philippon Research Institute
Patellofemoral Pain Syndrome
Tibiofemoral Mobilization in Patellofemoral Pain Syndrome
The aim of this research was to determine the effects of tibiofemoral joint mobilization in patients of patellofemoral pain syndrome. Tibiofemoral joint mobilization effects on pain and Range of Motion (ROM) in knee joint.
- Trial name
- NCT04225000
- Testing
- Exercise Group, Mobilization Group
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Osteoarthritis, Knee
Effects of Low Intensity Blood Flow Restriction on Clinical Outcomes in Women With Knee Osteoarthritis
Objective is to compare the effects of routine physical therapy with and without low intensity blood flow restriction on pain and quadriceps muscle strength in women with knee osteoarthritis.
- Trial name
- BFR (NCT04865692)
- Testing
- BFRT, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Knee Osteoarthritis
Efficacy and Safety of Panlongqi Tablet in Patients With Knee Osteoarthritis
This study evaluates the efficacy and safety of Panlongqi tablet compared with placebo in the treatment of knee osteoarthritis in adults.Half of participants will receive Panlongqi tablet in combination,while the other half will…
- Trial name
- NCT03327012
- Testing
- Treatment of Panlongqi Tablet
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
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