Clinical trials: Arthropathy of Knee
Knee Osteoarthritis, Persistent Postsurgical Pain
Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain
Chronic knee pain remains a disabling disease despite current treatment strategies. There is an increase in the prevalence of osteoarthritis (OA) of the knee in the general population, presently affecting approximately 450,000…
- Conditions
- Knee Osteoarthritis, Persistent Postsurgical Pain, Chronic Knee Pain
- Trial name
- COGENIUS (NCT05407610)
- Testing
- Conventional Radiofrequency ablation of the genicular nerves, Cooled Radiofrequency ablation of the genicular nerves
- Where
- 15 sites in Belgium, Netherlands
- Volunteers
- 400 people
- Sponsor
- Ziekenhuis Oost-Limburg
Knee Osteoarthritis
The Efficacy of Interferential Current Treatment on Knee Osteoarthritis
The effects of different carrier frequencies of interferential current on pain and function in patients with knee arthrosis will be compared
- Trial name
- NCT04015323
- Testing
- Interferential current
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Ege University
Osteoarthritis, Knee
A Controlled Surveillance of the Osteoarthritic Knee Microenvironment With Regenexx® SD Treatment
The primary objective of this study is to determine the levels of proteins and/or cellular components of the synovial fluid that are indicative of microenvironment phenotypes of the osteoarthritic knee compared to unilateral…
- Trial name
- NCT02370823
- Testing
- Regenexx SD
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Regenexx, LLC
Knee Injuries, Anterior Cruciate Ligament Rupture
Stopping OsteoARthritis After an ACL Tear
By 2040, 25% of Canadians will have osteoarthritis, a disabling joint condition. Most people think osteoarthritis only affects older adults, but 50% of the 700,000 Canadian youth who hurt their knee playing sports annually will…
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Rupture, Osteoarthritis, Knee
- Trial name
- SOAR (NCT06195423)
- Testing
- Stop OsteoARthritis (SOAR) program, Living Well after ACLR program
- Where
- 2 sites in Canada
- Volunteers
- 210 people
- Sponsor
- University of British Columbia
Knee Osteoarthritis, Task Performance and Analysis
Knee Osteoarthritis, Motor Control, Risk of Falls and Virtual Reality
The goal of this clinical trial is to learn about knee osteoarthritis, functionality, and risk of falls in community-dwelling adults aged 60 years and older.
- Conditions
- Knee Osteoarthritis, Task Performance and Analysis, Accidental Falls, Virtual Reality
- Trial name
- NCT06362785
- Testing
- Virtual Reality, Therapeutic exercise
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Pulsed Radiofrequency, Osteoarthritis, Knee
Pulsed Radiofrequency and Osteoarthritic Chronic Knee Pain
The purpose of this study is to investigate the efficacy and safety of pulsed radiofrequency of the saphenous nerve in the treatment of pain due to knee osteoarthritis (OA).
- Conditions
- Pulsed Radiofrequency, Osteoarthritis, Knee, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT04454710
- Testing
- Pulsed Radiofrequency
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Rome Tor Vergata
Knee Osteoarthritis
Implementation of Tele-Exercise for Management of Knee Osteoarthritis in Older Rural Primary Care Patients
Knee osteoarthritis (OA) is highly prevalent and a leading cause of pain that limits physical functioning in older adults. Clinical practice guidelines recommend physical exercise for managing symptoms of knee OA.
- Trial name
- NCT04706702
- Testing
- Tele-EnhanceFitness
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Washington
Pain, Activities of Daily Living
A Double-blind, Randomized, Parallel Group, Fase III Comparative Study With Rose Hip Powder Powder and Placebo Given to Patients With Mild to Moderate Osteoarthritis in the Knee or/and Hip
The trial is an investigator-initiated, double-blind, randomized, placebo-controlled phase III study. After the patient has receiving information about the study and after given written informed consent, the patient will be…
- Conditions
- Pain, Activities of Daily Living, Quality of Life
- Trial name
- NCT01459939
- Testing
- Rose-hip powder capsules
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hyben Vital ApS
Knee Osteoarthritis (OA)
Cross-Education From Unilateral Strength and Balance Training in Older Adults With Bilateral Knee Osteoarthritis
Kinesitherapy is one of the main tools in the rehabilitation of knee osteoarthritis, but is often limited due to pain, reduced functionality, and fear of falling in older adults.
- Trial name
- NCT07490977
- Testing
- 8-Week Unilateral Strength and Balance Program for the Less Affected Leg in Older Adults With Bilateral Knee Osteoarthritis, 8-Week Unilateral Balance Training Program for the Less Affected Leg in Older Adults With Bilateral Knee Osteoarthritis, 8-Week Unilateral Strength Training Program for the Less Affected Leg in Older Adults With Bilateral Knee Osteoarthritis
- Where
- Croatia
- Volunteers
- 45 people
- Sponsor
- University of Zagreb
Anterior Knee Pain
Comparison of Removing and Non-removing Patellofemoral Joint Osteophytes Following Medial Unicompartment Knee Arthroplasty
Background: Anterior knee pain (AKP) is a challenge following unicompartmental knee arthroplasty (UKA). Some surgeons remove patellofemoral joint (PFJ) osteophytes to reduce osteophyte impingement and AKP.
- Trial name
- NCT05367375
- Testing
- removing osteophyte at patellofemoral joint
- Volunteers
- 90 people
- Sponsor
- Thammasat University
MRI, Hemophilia
MRI Role in Knee Hemophilic Arthopathy
The aim of this study is to assess role of MRI in detecting synovial, cartilaginous , osseous abnormalities ، bleeding inside knee joint and to use a system for assessing HA as support for therapeutic regimes and for monitoring…
- Conditions
- MRI, Hemophilia, Arthropathy Hemophilic, Arthropathy of Knee
- Trial name
- NCT07233122
- Volunteers
- 95 people
- Sponsor
- Assiut University
Knee Osteoarthritis
Balneotherapy With Acquabios Thermal Water in Knee Osteoarthritis
The aim of the study is the evaluation of the effect of balneotherapy with Acquabios bicarbonate-alkaline-sodium thermal water in ameliorating some signs and symptoms of knee osteoarthritis in human subjects suffering from this…
- Trial name
- NCT05352477
- Testing
- Balneotherapy with thermal water, Balneotherapy with tap water
- Volunteers
- 88 people
- Sponsor
- University of Roma La Sapienza
Knee Osteoarthritis, Knee Arthritis
Chitosan Versus Glucosamine Phonophoresis in the Management of Knee Osteoarthritis
The study will be conducted to answer the following questions: Is there an effect of phonophoresis using glucosamine on pain level , function and range of motion in knee osteoarthritis patients ? Is there an effect of…
- Trial name
- NCT05420441
- Testing
- Phonophoresis with chitosan, Phonophoresis with glucoasmine, Conventional Physical Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Osteoarthritis, Knee
Efficacy and Mechanism of FSN Treatment for Senile Knee Osteoarthritis
The goal of this clinical trial is to compare FSN with oral Nonsteroidal Antiinflammatory Drugs (NSAIDs) in pain relief and improvement in knee function among elder people, the main questions it aims to answer are: Q1: Compared…
- Trial name
- NCT06328153
- Testing
- Fu's Subcutaneous Needling, Celecoxib
- Volunteers
- 60 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Knee Osteoarthritis
Validity And Reliability Of The Short Physical Performance Battery In Patients Undergoing Total Knee Arthroplasty
Objectives: Practical, applicable, valid, and reliable tools are needed to assess physical performance in patients with Total Knee Arthroplasty(TKA) in a variety of settings, including routine clinical assessment, research…
- Trial name
- NCT06201637
- Testing
- Performance Test
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Dokuz Eylul University
Osteo Arthritis Knee, Osteoarthritis
The Impact of Genicular Nerves Chemical Neurolysis on the Quality of Life of Patients with Advanced Knee Osteoarthritis.
Genicular nerves chemical neurolysis in advanced osteoarthritis of the knee joint.
- Trial name
- NCT06087601
- Testing
- 0.9% Sodium chloride, 95% ethanol
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis, Knee, Hypertrophy
Comparison Among the Effects of Blood Flow Restriction Training and Conventional Exercise in Knee Osteoarthritis.
The main objective of the study is to compare the effects of Blood flow Restriction training vs. traditional exercises on knee pain , knee functional disability and on quadriceps strength in patient with knee osteoarthritis.
- Trial name
- NCT05058794
- Testing
- Blood flow Restriction/Resistance Training, Conventional Therapy Group
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Comparison of INIT and Dry Needling on Trigger Points in Knee OA
The purpose of the study is to compare the effects of Integrated Neuromuscular Inhibition Technique and Dry Needling on Functional Disability, Pain and Range of Motion.
- Trial name
- NCT06437730
- Testing
- Integrated Neuromuscular Inhibition Technique:, Dry needling:
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Osteoarthritis,Knee
The Comparative Efficacy of Peri-articular and Intraarticular Tranexamic Acid in Total Knee Arthroplasty
Post-operative bleeding in total knee arthroplasty (TKA) can result in hypovolemic shock and unnecessity for allogenic blood transfusions.
- Trial name
- NCT03074994
- Testing
- Peri-articular TXA (15 mg/kg), Intraarticular TXA 2 g (40 mL), TXA combined with multimodal local anesthetic infiltration inject into peri-articular area
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Thammasat University
Knee Osteoarthritis, Anesthesia, Local
Liposomal Bupivacaine in Total Knee Arthroplasty
Pain management after total knee arthroplasty is essential for optimized clinical outcomes and higher satisfaction. Exparel (Pacira Pharmaceuticals, Parsippany, New Jersey, USA) is a long-acting Bupivacaine extended release…
- Trial name
- NCT03541265
- Testing
- Exparel, Adductor block protocol, peri-articular injection protocol
- Volunteers
- 70 people
- Sponsor
- Bronx-Lebanon Hospital Center Health Care System
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