Clinical trials: Arthropathy of Knee
Osteoarthritis, Knee Cutaneous Suture, Dermabond, Subcuticular Suture
Comparison of Postoperative Wound Between Dermabond Prineo(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) and Subcuticular Suture in Simultaneous Total Knee Arthroplasty
This study aims to compare the clinical results of postoperative wound between Dermabond PRINEO™(2-octyl Cyanoacrylate adhesive and polyester mesh) and subcuticular suture in simultaneous total knee arthroplasty There is previous…
- Trial name
- NCT04506580
- Testing
- DERMABOND™ PRINEO™(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) vs subcuticular nylon suture
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- The Catholic University of Korea
Primary Knee Osteoarthritis
Safety and Efficacy of Sahasthara ME vs Diclofenac ME for Treating Primary Knee Osteoarthritis
Background: Sahasthara is a traditional Thai herbal remedy used for the anti-inflammatory treatment of the musculoskeletal system, while diclofenac sodium is one of the most topically administered anti-inflammatory drug.
- Trial name
- NCT06184685
- Testing
- Sahasthara Microemulsion, Diclofenac Microemulsion
- Where
- Thailand
- Volunteers
- 87 people
- Sponsor
- Thammasat University
Osteoarthritis, Knee, Osteoarthritis, Hip
A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform
Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a…
- Trial name
- NCT03737149
- Testing
- mymobility with Apple Watch
- Where
- 30 sites in United States, Australia and 2 more
- Volunteers
- 6,559 people
- Sponsor
- Zimmer Biomet
Knee Pain Chronic, Muscle Pain
Efficacy of High and Low Intensity Percutaneous Electrolysis for the Treatment of Myofascial Pain Syndrome
Muscle pain is frequently attributed to myofascial pain syndrome (MPS) in which myofascial trigger points (MTrP) are a characteristic feature.
- Trial name
- NCT04390438
- Testing
- Percutaneous Electrolysis, Dry needling
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Universidad Francisco de Vitoria
Osteoarthritis, Knee
Study of FX005 for the Treatment of Pain in Patients With Osteoarthritis of the Knee
The purpose of this study is to evaluate the safety, efficacy and pharmacokinetics of FX005 for the treatment of pain in patients with osteoarthritis of the knee.
- Trial name
- NCT01291914
- Testing
- FX005
- Where
- 13 sites in Austria, Canada and 2 more
- Volunteers
- 140 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis
Exploring Massage Benefits for Arthritis of the Knee
The purpose of this study is to verify the efficacy of an 8-week course of manualized Swedish massage for reducing pain and increasing function compared to light-touch bodywork, and usual care, in 222 adults with OA of the knee.
- Trial name
- EMBARK (NCT01537484)
- Testing
- Massage Therapy
- Where
- 3 sites in United States
- Volunteers
- 222 people
- Sponsor
- Duke University
Knee Osteoarthritis
Intrawound Administration of Vancomycin in TKA
The purpose of this study is to determine the intra-articular and serum levels of vancomycin over the first 24 hours postoperatively after intra-articular administration of a standard dose of vancomycin in primary total knee…
- Trial name
- NCT05338021
- Testing
- Intrawound administration of vancomycin after closure of the arthrotomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Patello Femoral Syndrome, Patellofemoral Pain
Comparison of Concentric-eccentric Exercises in Patellofemoral Pain Syndrome
Patellofemoral pain syndrome is due to dysfunctional dynamic knee valgus resulting from decrease in strength of hip abductors or abnormal rear-foot eversion with pes pronatus valgus.
- Conditions
- Patello Femoral Syndrome, Patellofemoral Pain, Knee Pain Chronic
- Trial name
- NCT06197958
- Testing
- eccentric exercises, concentric exercises
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Osteoarthritis
Complex Āyurvedic Treatment in Osteoarthritis of the Knee Compared to Standard Care.
The aim of this study is to evaluate the effectiveness of a complex āyurvedic diagnosis and treatment compared to conventional standard care in patients with OA of the knee.
- Trial name
- CARAKA (NCT01225133)
- Testing
- Complex Ayurvedic Treatment, Conventional Care
- Where
- 2 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Charite University, Berlin, Germany
Osteoarthritis, Knee
An Effectiveness and Safety Study of IDEA-033 in Comparison to Oral Naproxen and Placebo for the Treatment of Osteoarthritis of the Knee
The purpose of this study is to identify the dose(s) of IDEA-033 that will provide a meaningful effect for treating osteoarthritis of the knee.
- Trial name
- NCT00211549
- Testing
- IDEA-033
- Where
- 100 sites in United States
- Volunteers
- 875 people
- Sponsor
- IDEA AG
Osteoarthritis
Comparison of Stability and Outcomes in Single-radius Femoral Component for Total Knee Arthroplasty
This is a comparison of the functional results and Varus-Valgus Stability in Single-radius versus Multi-radius Femoral Component for Total Knee Arthroplasty.
- Trial name
- NCT01379755
- Where
- South Korea
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
Primary Total Knee Arthroplasty, Intraosseous Morphine Injection
Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty
Study investigators propose to investigate if a bony injection of pain medication during a knee replacement will help pain levels following primary knee replacement surgery. To investigate this, 86 patients will be enrolled.
- Conditions
- Primary Total Knee Arthroplasty, Intraosseous Morphine Injection, Knee Osteoarthritis
- Trial name
- NCT06716749
- Testing
- Morphine, Vancomycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Carilion Clinic
Knee Osteoarthritis
Phase I Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis
In recent years, the incidence rate and disability rate of osteoarthritis have continued to grow, and it has become a common chronic disease of elderly patients, second only to the "three highs", and poses a continuous threat to…
- Trial name
- NCT06463847
- Testing
- UC-MSCs
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Knee Osteoarthritis, Virtual Reality
The Effects of Non-Immersive Virtual Reality Exercises on Muscle Excitability in Knee Osteoarthritis
The main goal of this sham-controlled clinical trial is to learn the excitability levels of the muscles around the knee and balance using objective measurement methods in patients with knee osteoarthritis of non-immersive virtual…
- Trial name
- NCT05595317
- Testing
- Non-immersive Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Mehmet Sönmez
Osteoarthritis, Knee
Medial Unicondylar Knee Arthroplasty vs Total Knee Arthroplasty
In treatment of isolated medial unicondylar osteoarthritis of the knee (MU-OA), it is possible to choose between surgery with a unicondylar knee arthroplasty (UKA), or a total knee arthroplasty (TKA).
- Trial name
- UKAvsTKA (NCT03396640)
- Testing
- Unicondylar Knee Arthroplasty, Total Knee Arthroplasty
- Where
- 11 sites in Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Arthropathy of Knee Joint
Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block
To evaluate an analgesic effect without basal administration of local anesthetics for patient-controlled femoral nerve block (with sciatic nerve block) after total knee arthroplasty.
- Trial name
- NCT01198340
- Testing
- PC-FNB with basal administration of local anesthetics, PC-FNB without basal local anesthetics
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Okayama University
Osteoarthritis, Sarcopenia
Prevalence of Sarcopenia and Its Associated Factors in Patients With Knee Osteoarthritis in a Tertiary Care Hospital in Upper Egypt
Osteoarthritis (OA) and sarcopenia are two highly prevalent, interconnected geriatric syndromes that often coexist, leading to a condition termed "osteosarcopenia".
- Trial name
- NCT07566520
- Where
- Egypt
- Volunteers
- 224 people
- Sponsor
- Assiut University
Knee Osteoarthritis, Musculoskeletal Disease
Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.
The goal of this clinical trial is to find out which type of steroid medicine, when added to a standard pain-control injection during total knee replacement surgery, works best at reducing pain, limiting opioid use, and improving…
- Conditions
- Knee Osteoarthritis, Musculoskeletal Disease, Surgery
- Trial name
- TKACSI (NCT07151417)
- Testing
- PAI, PAI + steroid, PAI + zilretta
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Walter Reed National Military Medical Center
Angulation Deformity of Long Bone (Disorder), Acquired Deformity of Knee Joint (Disorder)
Use of Motion Sensors in Correction Procedures of Long Bone Deformities in the Pediatric Age Group
Motion sensors will be used in long bone deformity surgery in pediatric patients. In patients whose deformity status is determined before the surgery, 2 wires will be placed in the same plane from the proximal and distal of the…
- Trial name
- NCT06516497
- Testing
- Group using traditional method in long bone deformity correction, Group using computer-aided sensors in long bone deformity correction
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ataturk University
Knee Osteoarthritis, Energy Transfer Capacitative and Resistive Therapy
Efficacy of TECAR Therapy in Patients With Knee Osteoarthritis
Objective: The aim of the present study was to investigate the treatment efficacy of TECAR therapy, a modern application that has been increasingly used in recent years, compared to conventional physical therapy applications in…
- Trial name
- NCT06418360
- Testing
- TECAR, conventional physical therapy; Transcutaneous Electrical Nerve Stimulation, hotpack
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
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