Clinical trials: Arthropathy of Knee
Patellofemoral Pain Syndrome
Utilizing the Trunk as a Proximal Lever to Strengthen the Hip Musculature and Alter Lower Extremity Function
Does a rotary based triplanar exercise intervention that utilizes the trunk as a proximal lever, strengthen the hip and alter dynamic LE alignment in running females?
- Trial name
- NCT03285464
- Testing
- Triplanar Rotary Resistance
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- High Point University
Knee Osteoarthritis
Intra-articular Oxygen-ozone Therapy for the Treatment of Knee Osteoarthritis Compared With Hyaluronic Acid
Knee osteoarthritis is a very common pathology, characterized by pain, stiffness and functional deficit. The various therapeutic options used include anti-inflammatory drug treatment, physiokinesitherapy, minimally invasive…
- Trial name
- NCT04426721
- Testing
- Ozone, Hyaluronic Acid
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Humanitas Clinical and Research Center
Osteoarthritis, Knee
Safety and Efficacy of the Journey II BCS Total Knee System
Assess the safety and efficacy of the JOURNEY II BCS Total Knee System in subjects with degenerative knee disease requiring primary total knee replacement.
- Trial name
- NIMBLE (NCT01705067)
- Testing
- TKA with Journey II BCS Total Knee System
- Where
- 12 sites in United States
- Volunteers
- 209 people
- Sponsor
- Smith & Nephew, Inc.
Knee Osteoarthritis
Comparison of the Effects of Static and PNF Hamstring Stretching Exercises in Patients With Knee Osteoarthritis
The aim of this study is to determine and compare the effects of static and PNF hamstring stretching exercises on joint pain, hamstring flexibility and functional status in patients with knee osteoarthritis.
- Trial name
- NCT04645238
- Testing
- Static Stretching, PNF Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Dokuz Eylul University
Total Knee Arthroplasty, Knee Replacement
Investigating Patient Satisfaction With Smart Knee Implants
The main goal of this study is to see if there is a connection between the social and economic resources available in a patient's neighborhood (measured by the Area Deprivation Index, ADI) and their recovery after knee…
- Conditions
- Total Knee Arthroplasty, Knee Replacement, Knee Replacement Arthroplasty, Knee Osteoarthritis
- Trial name
- NCT06968143
- Testing
- Smart Knee Implant
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Knee Disease, Knee Deformity
Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery
The ultrasound-guided selective blockade of the saphenous nerve in the adductor canal provides effective analgesia and reduces postoperative pain in patients undergoing arthroscopic medial meniscectomy.
- Conditions
- Knee Disease, Knee Deformity, Knee Pain Chronic, Knee Arthropathy
- Trial name
- NCT06084403
- Testing
- 20 ml volume adductor canal block, 30 ml volume adductor canal block, 40 ml volume adductor canal block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Knee Osteoarthritis
Evaluating the Efficacy of Lateral Heel Wedges of Osteoarthritis of the Knee
This study is looking at the efficacy of a sloped insole in patients with knee osteoarthritis. Regularly wearing a sloped insole over the course of one year will result in a wider joint space by x-ray in 60% of the subjects, a…
- Trial name
- NCT02254473
- Testing
- Wedge Insert, Flat Insert
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Knee Osteoarthritis
Effects of Platelet-Rich Plasma and Ozone Therapy in Knee Osteoarthritis
Knee osteoarthritis can frequently occur with advancing age. In cases of pain that persists despite hot/cold applications, drug therapy and exercise, intra-articular injections are considered.
- Trial name
- NCT06631456
- Testing
- PRP injection, Ozone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Knee Osteoarthritis
Effectiveness of Oral Hyaluronic Acid in Knee Osteoarthritis
This study was a randomized, double-blind, placebo-controlled study evaluating the efficacy of an oral liquid HA supplement (A+HA) in symptoms relief and improvement of quality of life in knee osteoarthritis patients with mild…
- Trial name
- NCT04352322
- Testing
- A+HA(tm)
- Where
- Taiwan
- Volunteers
- 47 people
- Sponsor
- China Medical University Hospital
Osteoarthritis, Osteoarthritis of the Hip or Knee
Conversations in Health Literacy Using AI Technology for Osteoarthritis Patients
The goal of this clinical trial is to assess the use of a generative artificial intelligence large language model chatbot in improving decision making factors in patients with hip and knee osteoarthritis.
- Trial name
- CHAT-OA (NCT06778486)
- Testing
- Artificial Intelligence Chatbot
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Knee Osteoarthritis, Edema
Control of Edema in the Knee in Patients With Knee Osteoarthritis
The aim of this study was to compare the effectiveness of exercise and classical massage in the control of knee edema in patients with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Edema, Edema Leg
- Trial name
- NCT06010394
- Testing
- conventional physiotherapy, exercises for the knee area, payment oriented massage
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Uskudar University
Knee Osteoarthritis
The Effect of "Laying on of Hands" in Older Women With Knee Osteoarthritis
Osteoarthritis (OA) is the most common form of chronic degenerative joint disease, as well as the main cause of pain and disability in older persons worldwide.
- Trial name
- NCT02917356
- Testing
- Spiritual laying on of hands (SP), Non-spiritual Laying on of Hands, Control group
- Where
- Brazil
- Volunteers
- 105 people
- Sponsor
- Federal University of Juiz de Fora
Osteoarthritis, Knee
Residual Pain After Successful Implant of Metaphyseal Sleeves in Total Knee Arthroplasty
: Total knee revision arthroplasty is increasing in daily practice and will become more relevant in the years to come. Bone loss is a significant challenge in total knee arthroplasty (TKA) especially in revision procedures.
- Trial name
- NCT04995679
- Testing
- Implant of metaphyseal sleeves in Total knee arthroplasty
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- University of Milan
Osteoarthritis, Knee, Knee Osteoarthritis
AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee
This is a phase 3 randomized study to confirm the efficacy of an intra-articular injection of Ampion™ in adults with pain due to severe osteoarthritis of the knee.
- Conditions
- Osteoarthritis, Knee, Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic
- Trial name
- NCT03182686
- Testing
- 4 mL injection of Ampion
- Where
- 13 sites in United States
- Volunteers
- 168 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Exercise
Effectiveness of Mulligan Mobilization Technique and Core Stabilization Exercise With Knee Osteoarthritis
Osteoarthritis (OA) is a chronic disease process characterized by degeneration and inflammation in the joint cartilage and subchondral bone, synovial fluid and joint capsule.
- Trial name
- NCT04540341
- Testing
- Mulligan mobilization, Core stabilization, Conventional therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Pamukkale University
Knee Osteoarthritis, Total Knee Replacement
The Effect of Laser Acupuncture Intervention to the Prognosis After TKR Surgery
This study protocol is mainly focus on the patients, who suffer pain, swelling, or range of motion limitation after total knee replacement (TKR) surgery procedure,would be relieved by use non-invasive laser acupuncture to stimuli…
- Trial name
- NCT05263856
- Testing
- laser acupuncture
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
Knee Osteoarthritis, Knee Arthroplasty
Evaluation of Fixation Achievable in Revision Total Knee Arthroplasty Implementing Latest-Generation Implant Technology
This is a prospective randomized control trial that aims to investigate fixation of implants after revision total knee replacement.
- Trial name
- NCT03276351
- Testing
- Long-Stemmed with Hybrid Fixation, Short-Stemmed with Augmented Fixation
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis
Single-use Efficiency Instruments With Patient Specific Technique (MyKnee®) Versus Traditional Metal Instruments With Conventional Surgical Technique
To compare economic factors and the rate of adverse events between two types of instrumentation used for total knee replacement: Single-use Efficiency Instruments with Patient Specific Technique (MyKnee®) Traditional Metal…
- Trial name
- NCT03148379
- Testing
- Customized patient instruments, Traditional Metal Instruments
- Where
- 5 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Knee Osteoarthritis
Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Knee Osteoarthritis (STRIDES)
This phase 3 study was a multicenter, randomized, double-blind, placebo-controlled study of lorecivivint injected intra-articularly (IA) into the target (most painful) knee joint of moderately to severely symptomatic…
- Trial name
- NCT05603754
- Testing
- Lorecivivint
- Where
- 44 sites in United States
- Volunteers
- 499 people
- Sponsor
- Biosplice Therapeutics, Inc.
Knee Osteoarthritis
Observational Clinical Investigation of Arthrosamid in Knee Osteoarthritis
This is a prospective, long-term, observational, all-comers, open-label, multi-centre clinical investigation enrolling subjects with knee osteoarthritis who is eligible for treatment with Arthrosamid® according to the Instruction…
- Trial name
- LUNA (NCT05057559)
- Where
- 9 sites in Denmark, France and 3 more
- Volunteers
- 201 people
- Sponsor
- Contura
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