Clinical trials: Arthroplasties, Replacement
Total Knee Replacement, Arthroplasty
The Effect of Patellar Eversion on Functional Outcomes in Primary Total Knee Arthroplasty
Short and long term outcomes of total knee arthroplasty patients surgically exposed with patellar eversion are compared to those patients exposed by laterally retracting the patella.
- Conditions
- Total Knee Replacement, Arthroplasty, Patella
- Trial name
- NCT01777009
- Testing
- Primary Total Knee Replacement Surgery
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwell Health
Arthroplasty, Knee Replacement, Pain Control
Self Medication With Oral Morphine After Total Knee Arthroplasty.
The study aims to compare two post operative pain management strategy's, traditional nurse dispensed pain control versus patient self medication.
- Trial name
- NCT01226186
- Testing
- Nurse dispensed oral morphine., Patient self medication of oral morphine.
- Where
- United Kingdom
- Volunteers
- 144 people
- Sponsor
- The Royal Bournemouth Hospital
Arthroplasty, Replacement, Hip, Blood Transfusion
Comparison in Need for Bank Blood Between Patients Undergoing Total Hip Surgery That Either Receive Their Own Blood Back or Not
The study is a prospective, controlled, randomised and assessor blind study that investigate if the need for bank blood transfusion could be reduced in patients, undergoing primary or revision total hip replacement surgery, who…
- Conditions
- Arthroplasty, Replacement, Hip, Blood Transfusion, Blood Transfusion, Autologous
- Trial name
- NCT00822588
- Testing
- Sangvia® System
- Where
- 6 sites in Austria, Netherlands and 2 more
- Volunteers
- 227 people
- Sponsor
- Wellspect HealthCare
Arthroplasty, Replacement, Thromboembolism
Pradaxa (Dabigatran Etexilate 220 mg/q.d. in the General Population After Hip or Knee Replacement Surgery
An observational cohort study on safety and efficacy of the 220 mg dose Pradaxa to generate additional data in predefined sub populations of patients at increased risk of bleeding or VTE
- Trial name
- NCT00846807
- Where
- 112 sites in Austria, France and 7 more
- Volunteers
- 5,476 people
- Sponsor
- Boehringer Ingelheim
Arthroplasty, Replacement, Hip
Use of Local Analgesia With Epinephrine During Total Hip Arthroplasty (THA)
The aim is to determine if the use of infiltration with an adrenalin solution in the operative field of Total Hip Arthroplasty (THA), allays a significant reduction of the cumulated volume of bleeding (pre and post operative)…
- Trial name
- NCT00980616
- Testing
- ropivacaine, physical serum and adrenalin
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Clermont-Ferrand
Spinal Anesthesia, Total Knee Replacement Arthroplasty
ED50 and ED95 of Intrathecal Bupivacaine With or Without Epinephrine for Total Knee Replacement Arthroplasty
This prospective randomized double-blind dose-response study is aimed to investigate the ED50 and ED95 of intrathecal bupivacaine with or without epinephrine 100 mcg for total knee replacement arthroplasty.
- Trial name
- NCT01264575
- Testing
- intrathecal bupivacaine 6 mg with 100 mcg of epinephrine, intrathecal bupivacaine 7 mg with 100 mcg of epinephrine, intrathecal bupivacaine 8 mg with 100 mcg of epinephrine
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- Seoul Medical Center
Knee Osteoarthritis, Arthroplasty, Replacement, Knee
Addressing Patients' Expectations of Total Knee Arthroplasty in a Randomized Trial
The goals of this study are to develop and test an educational intervention to address patients' expectations of long-term outcomes of total knee arthroplasty.
- Trial name
- NCT00197977
- Testing
- Educational program to address patients' expectations
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Hospital for Special Surgery, New York
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Expectations, Satisfaction and Quality of Life in Total Hip Arthroplasty
The goals of this study are to identify predictors of improvement in quality of life and satisfaction with total hip arthroplasty three to five years after surgery.
- Trial name
- NCT00197990
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- Hospital for Special Surgery, New York
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Addressing Patients' Expectations of Total Hip Arthroplasty in a Randomized Trial
The goals of this study are to develop and test an educational intervention to address patients' expectations of long-term outcomes of total hip arthroplasty.
- Trial name
- NCT00198003
- Testing
- Educational program to address patients' expectations
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Hospital for Special Surgery, New York
Anemia, Arthroplasty
Establishment of Optimal Transfusion Threshold After Major Orthopedic Surgery
The purpose of this study is to determine whether a higher threshold for transfusion with red blood cells improves the postoperative ambulation.
- Conditions
- Anemia, Arthroplasty, Replacement, Hip
- Trial name
- NCT00906295
- Testing
- Allowed drop in hemoglobin to 4.5-5.5 mmol/L, Allowed drop in hemoglobin to level between 5.6-6.5 mmol/L
- Where
- 2 sites in Denmark
- Volunteers
- 67 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Arthroplasty, Replacement, Knee
Short- Versus Long-duration Tourniquet Use During Total Knee Replacement (TKR)
To establish whether a short duration of tourniquet application (from cement fixation to cement setting)is associated with better patient functional outcomes compared to a long duration of tourniquet application (from surgical…
- Trial name
- NCT01162720
- Testing
- Long duration tourniquet, Short duration tourniquet
- Where
- Australia
- Volunteers
- 65 people
- Sponsor
- Fairfield Hospital, Australia
Arthroplasty, Replacement, Knee
A Comparison of Sartorius Vs. Quadriceps Evoked Motor Response for Femoral Nerve to Prevent Secondary Catheter Failure
Objective: Continuous nerve block (freezing the nerve) is needed for knee replacement surgery to reduce pain, increase rehabilitation and discharge patients home fast.
- Trial name
- NCT01313546
- Testing
- Stimulation of quariceps muscle
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Sunnybrook Health Sciences Centre
Thromboembolism, Arthroplasty Replacement, Knee
Safety Study of Stopping Thromboprophylaxis Based on Ultrasound Results After Total Knee Replacement
The purpose of this study is to determine whether stopping Low Molecular Weight Heparin (LMWH) thromboprophylaxis is safe after total knee joint replacement.
- Trial name
- NCT00362492
- Testing
- Bilateral ultrasound examination 7+/- 2 after surgery
- Where
- 17 sites in France
- Volunteers
- 850 people
- Sponsor
- University Hospital, Caen
Arthroplasty, Replacement, Knee, Nerve Block
The Efficacy of Automated Intermittent Boluses for Continuous Femoral Nerve Block: a Prospective, Randomized Comparison to Continuous Infusions
The optimal infusion technique (continuous rate vs. intermittent bolus) for peripheral nerve blocks has not been established. To our knowledge, this is the first study to compare the efficacy of an automated intermittent bolus…
- Trial name
- NCT01226927
- Testing
- Automated intermittent bolus
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Medical University of South Carolina
Arthroplasty, Replacement, Knee, Patient-controlled Analgesia
Postoperative Patient Controlled Epidural Analgesia After Total Knee Arthroplasty With 2ug/ml Fentanyl Combine With 0.2% Ropivacaine or 0.2% Levobupivcaine
Postoperative epidural analgesia (EA) is an effective and well-accepted modality of pain relief technique after having total knee replacement operation(1,4).
- Trial name
- NCT01158586
- Testing
- Levobupivacaine
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- United Christian Hospital
Arthroplasty, Replacement, Hip
Evaluation of Four Surgical Techniques in Primary Total Hip Arthroplasty
Current "Minimally Invasive THR" includes: (1) Minimally Invasive Two-Incision THR (MIS-2), (2) Minimally Invasive Modified Watson-Jones THR (MIS-WJ).
- Trial name
- NCT01031732
- Testing
- MIS-2 THA, MIS-WJ, MIS-AL THA
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Bone Density, Arthroplasty, Replacement, Hip
The Effectiveness of Two Osteoporosis Drugs on Prosthetic Bone Mineral Density (BMD) Loss After Total Hip Arthroplasty(THA)
The purpose of this study is to evaluate whether alendronate and alfacalcidol are effective on prosthetic or lumbar spine BMD after total hip arthroplasty.
- Trial name
- ETOD (NCT01020253)
- Testing
- alendronate, alfacalcidol
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Yokohama City University Medical Center
Total Knee Arthroplasty, Arthroplasty, Replacement, Hip
Retrospective Chart Analysis in the Effective Use of FloSeal in Post-Operative Joint Replacements
The purpose of this analysis is to compare Hemoglobin and Hematocrit levels following total hip or knee arthroplasty. The utilization of FloSeal intraoperatively will improve hemostasis postoperatively.
- Trial name
- NCT00958945
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Desert Orthopedic Center Medical Research Foundation
Total Knee Arthroplasty (Replacement)
Safety and Efficacy Study of 4975 in Patients Undergoing Total Knee Replacement
Evaluate the efficacy, tolerability, safety, and pharmacokinetics of 4975 in patients undergoing total knee replacement
- Trial name
- NCT00681356
- Testing
- 4975, 15 and 5 mg, 4975 - 5 mg
- Where
- 25 sites in United States
- Volunteers
- 214 people
- Sponsor
- Anesiva, Inc.
Arthroplasty, Replacement, Hip
Total Hip Replacement Study With XRP4563 (Enoxaparin Sodium)
This study is performed to confirm the optimal dose for THR (total hip replacement).
- Trial name
- NCT00349180
- Testing
- Enoxaparin sodium
- Where
- Japan
- Volunteers
- 156 people
- Sponsor
- Sanofi