Clinical trials: Arthroplasties, Replacement
Arthroplasty, Replacement, Hip
Multicentre Prospective Study to Evaluate Long-term Clinical Outcomes of the Sirius Cemented Femoral Stem
The purpose of this multicentre, prospective study is: Document the Clinical and Radiographic performance of the stem at 3 months, 1 year, 3 years, 5 years, 7 and 10 years. Report Safety and Survivorship up to 10 years F/up.
- Trial name
- Sirius (NCT02371382)
- Testing
- Arthroplasty hip
- Where
- 2 sites in Denmark, United Kingdom
- Volunteers
- 250 people
- Sponsor
- Zimmer Biomet
Arthroplasty, Overweight and Obesity
Healthy Living After Knee Replacement
The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to…
- Trial name
- NCT05190666
- Testing
- PACE Weight Loss program, Chronic Disease Self-Management
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Lower-body Total Joint Replacement
Automatic Physiotherapy and Rehabilitation System for Lower Body Total Joint Replacement
Physiotherapists spend a large amount of their time with patients observing their rehabilitation techniques. A patient going through rehabilitation exercises are routine and does not necessarily require the attention of the…
- Trial name
- NCT02324829
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of Waterloo
ARTHROPLASTY, REPLACEMENT
American Joint Replacement Registry
The American Joint Replacement Registry is a not-for-profit 501(c)(3) organization for data collection and quality improvement initiatives for total hip and knee replacements.
- Trial name
- AJRR (NCT01909375)
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- American Joint Replacement Registry
Knee Osteoarthritis
Stability of Contemporary Knee Arthroplasty
Total joint replacement is an efficacious treatment for osteoarthritis of hips and knees. Both total knee replacement (TKR) and total hip replacements (THR) have excellent implant survivorship.
- Trial name
- NCT02861794
- Testing
- Medacta International, GMK Sphere medially stabilized knee
- Where
- Norway
- Volunteers
- 44 people
- Sponsor
- Oslo University Hospital
Post-traumatic Osteoarthritis
A Biologic Joint Replacement Strategy to Treat Patients With Severe Knee Trauma and Post-Traumatic Knee Osteoarthritis
With IRB approval and informed consent, patients (n=10) (18-50 years old) with post-traumatic knee OA and requiring a tibial plateau and meniscus arthroplasty plus a femoral condyle arthroplasty will be enrolled in the study.
- Trial name
- NCT03257371
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- James Stannard
Total Knee Anthroplasty
Genicular Nerve Block Added to Femoral Nerve Block for Analgesia After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a common orthopedic procedure in which effective postoperative pain management is important for early mobilization and rehabilitation.
- Trial name
- GNB-FNB (NCT07478783)
- Testing
- Ultrasound-guided Femoral Nerve Block, ltrasound-guided Genicular Nerve Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Recovery Following Primary Total Knee Arthroplasty
Independent Exercise Compared With Formal Rehabilitation Following Primary Total Knee Replacement
In this study we plan to compare the efficacy of independent exercises performed by the patients at home to formal rehabilitation therapy following primary total knee replacement.
- Trial name
- NCT01826305
- Testing
- Formal Rehabilitation Therapy, Independent Exercise Cohort
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, San Francisco
Arthroplasty, Replacement, Hip
Intraarticular Analgesia After Total Hip Arthroplasty, a Randomised Study
The purpose of this study is to determine whether wound infiltration with following single-shot bolus injection with local anesthetic and NASIDs are effective in the treatment of postoperative pain after total hip replacement…
- Trial name
- NCT00289419
- Testing
- Epidural Ropivacaine, morphine, Ropivacaine, Ketorolac and Adrenaline
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Arthroplasty, Replacement, Knee, Thromboembolism
RE-MODEL Dabigatran Etexilate 150mg or 220mg Once Daily (o.d.) Versus (v.s.) Enoxaparin 40mg o.d. for Prevention of Thrombosis After Knee Surgery
A phase III, randomised, parallel-group, double-blind, active controlled study to investigate the ef ficacy and safety of two different dose regimens of orally administered dabigatran etexilate capsule s [150 or 220 mg once daily…
- Trial name
- NCT00168805
- Testing
- enoxaparin, dabigatran etexilate
- Where
- 105 sites in Australia, Austria and 13 more
- Volunteers
- 2,101 people
- Sponsor
- Boehringer Ingelheim
Osteoarthritis
Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
There are two cartilage structures, called menisci, in each knee joint. A torn meniscus can be caused by a traumatic injury or aging-related degeneration.
- Trial name
- NCT00597012
- Testing
- Arthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
- Where
- 7 sites in United States
- Volunteers
- 351 people
- Sponsor
- Brigham and Women's Hospital
Arthroplasty, Replacement, Knee, Analgesia
Analgesic Effect of Peripheral Cutaneous Nerve Block of Knee Joint After Total Knee Arthroplasty
Local anesthesia was performed on patients with total knee arthroplasty (TKA) through two different injection sites of local anesthetics and two local anesthetic drug .
- Trial name
- NCT05202730
- Testing
- New local anesthesia injection site and new local anesthetic drug formulation.
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Diwuweilong
Venous Thrombosis, Arthroplasty, Replacement, Hip
Lower Limb Blood Flow Geko vs Foot Pump
The aim of this pilot study was to assess venous flow parameters in patients following total hip arthroplasty, comparing an intermittent pneumatic compression foot device with a portable neuromuscular electrostimulator device.
- Trial name
- NCT03317145
- Testing
- Neuromuscular electrostimulation (NMES) device, Intermittent pneumatic compression (IPC) device
- Volunteers
- 10 people
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Arthroplasty, Replacement, Physical Therapy
Effectiveness of a Novel Gaming System on Post-operative Rehabilitation Outcomes After Total Knee Arthroplasty
This study aims to evaluate the effectiveness of a novel, game-based rehabilitation system, consisting a sensor-equipped knee sleeve and a mobile application, on rehabilitation outcomes after Total Knee Arthroplasty (TKA)…
- Trial name
- NCT04080401
- Testing
- Game-based rehabilitation exercise, Conventional brochures of rehabilitation exercise
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Tan Tock Seng Hospital
Hip and Knee Replacement Surgeries
California Joint Replacement Registry
The California Joint Replacement Registry (CJRR) was created to meet the need for comprehensive, scientific assessment of devices, treatment protocols, surgical approaches, and patient factors influencing the results of hip and…
- Trial name
- CJRR (NCT01787812)
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- California Joint Replacement Registry
Pain, Postoperative
Biopsychosocial Impact on Caregivers in Patients Undergoing Joint and Spine Surgery
The purpose of this study is to describe the biopsychosocial impact of caregivers in patients undergoing total knee arthroplasty, total hip arthroplasty, and cervical/thoracic/lumbar spine surgery.Defining such impacts may offer…
- Trial name
- NCT03059602
- Testing
- No specific treatment based intervention-health measurement instrument
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Osteoarthritis, Rheumatoid Arthritis
Total Knee Replacement With the ROCC Knee
The purpose of this study was to assess the results of a Total Knee prosthesis specifically intended to enhance functional performance , especially in terms of physical and sports activity.
- Trial name
- NCT02127619
- Testing
- Total knee replacement with the ROCC® knee prosthesis
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Bercovy, Michel, M.D.
Knee Osteoarthritis
Pre-emptive Effect of Duloxetine in the Second Knee in Staged Total Knee Arthroplasty
In Korea, the interval between knee arthroplasties is usually 1 week. According to previous studies, when total knee arthroplasty was performed at 1-week intervals, total bleeding was reduced and the period of hospital stay was…
- Trial name
- NCT03792828
- Testing
- Duloxetine HCl 30mg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Arthroplasty, Replacement, Knee
Randomised Total Knee Arthroplasty With Attune S+ or NexGen CR
The primary purpose of this study is to evaluate the clinical performance of the Attune S+ knee primarily based on evaluation with use of Oxford Knee Score. The NexGen TKR will be used as reference standard.
- Trial name
- NexGe (NCT05464641)
- Testing
- Oxford knee score
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Göteborg University
Hemorrhage, Arthroplasty, Replacement, Hip
Tranexamic Acid vs. Quixil - Reducing Blood Loss in Joint Replacement
We will compare the effectiveness of Quixil and Tranexamic acid in reducing bleeding during hip and knee joint replacements.
- Conditions
- Hemorrhage, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT00378872
- Testing
- IV Tranexamic acid 10mg/kg pt body weight, Quixil topical sealant
- Where
- United Kingdom
- Volunteers
- 132 people
- Sponsor
- Golden Jubilee National Hospital
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