Clinical trials: Arthroplasty, Replacement, Shoulder
Osteo Arthritis Shoulders
Glenoid Bone Grafting for RTSA: Clinical & Radiographic Outcomes
This study will look at patient radiographic and functional outcomes who have or will undergo a reverse, extended peg, shoulder arthroplasty (replacement) that requires the use of glenoid bone grafting.
- Trial name
- EPBG (NCT03151109)
- Testing
- CT Scan
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Washington University School of Medicine
Arthritis
Followup of Glenoid Fix Utilizing Auto Bone Graft in Shoulder Replacement
This is a case study to evaluate the adequacy of fixation and functional outcome of the glenoid anchor peg following autologous bone grafting around the prosthesis at the time of implant.
- Trial name
- NCT00670852
- Testing
- X-rays and CT scan
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Glenohumeral Osteoarthritis
Poly vs Hybrid Glenoid in Stemless aTSA
Participants are randomized 1:1 to receive either a cemented all-polyethylene pegged glenoid or a hybrid trabecular titanium-pegged glenoid during anatomic total shoulder arthroplasty.
- Trial name
- Poly vs hybrid (NCT07520721)
- Testing
- Anatomic total shoulder arthroplasty with cemented all-polyethylene pegged glenoid, Anatomic total shoulder arthroplasty with hybrid trabecular titanium central-peg glenoid
- Where
- Netherlands
- Volunteers
- 94 people
- Sponsor
- Spaarne Gasthuis
Shoulder Arthroplasty
Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty
The purpose of this clinical trial is to evaluate the short-term clinical outcomes of patients undergoing total shoulder arthroplasty who receive an extended postoperative course of oral tranexamic acid
- Trial name
- NCT06902714
- Testing
- oral tranexamic acid
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Shoulder Injuries, Patient Satisfaction
Conjoint Tendon Resection During Reverse Total Shoulder Arthroplasty
Reverse total shoulder arthroplasty (RTSA) can reliably restore active forward elevation, abduction, and external rotation, which are often lost in patients with massive rotator cuff tears.
- Conditions
- Shoulder Injuries, Patient Satisfaction, Internal Rotation Contracture-shoulder
- Trial name
- NCT05753904
- Testing
- Conjoint Tendon Resection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Humeral Fracture, Proximal
Reverse Total Shoulder Arthroplasty Versus Hemiarthroplasty for Displaced 3- and 4-part Proximal Humeral Fractures
Proximal humeral fractures are common injuries with the highest incidence being amongst the elderly. Most proximal humeral fractures are nondisplaced or minimally displaced.
- Trial name
- NCT03383991
- Testing
- Reverse Total Shoulder Arthroplasty, Hemiarthroplasty
- Sponsor
- Karolinska Institutet
Osteoarthritis, Arthropathy
Liposomal Bupivacaine for Pain Control After Total Shoulder Arthroplasty
This study will compare interscalene nerve block versus liposomal bupivacaine (Exparel) for pain control after total shoulder replacements.
- Conditions
- Osteoarthritis, Arthropathy, Shoulder Pain, Closed Fracture Proximal Humerus, Four Part
- Trial name
- NCT02762071
- Testing
- Liposomal bupivacaine, Interscalene Nerve Block
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- Johns Hopkins University
Proximal Humeral Fracture, Reverse Total Shoulder Arthroplasty
Duration of Immobilization After Reverse Total Arthroplasty for Proximal Humerus Fractures
The purpose of this study is to evaluate compare postoperative range of motion in patients who are given a sling for comfort only and allowed to start early active range of motion compared to patients who are placed in a sling…
- Trial name
- NCT06133920
- Testing
- Early Range of Motion, Immobilization
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cooper Health System
Shoulder Arthritis, Blood Loss, Surgical
Effect of TXA on Blood Loss in Reverse Total Shoulder Arthroplasty
Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent that has been well studied and routinely used for hip and knee arthroplasty.
- Conditions
- Shoulder Arthritis, Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
- Trial name
- NCT06638749
- Testing
- Tranexamic Acid, Normal Saline
- Where
- United States
- Sponsor
- University of Kansas Medical Center
Shoulder Injuries
Increased Home-based Physical Therapy Adherence Using BAND Connect's VirtuaCare™ Platform
This study aims to enhance at-home therapy by introducing a new device called the BAND Connect's VirtuaCare™ platform. The study aims to determine whether patients can improve their adherence to at-home exercises using this…
- Trial name
- NCT05876208
- Testing
- BAND Connect's VirtuaCare™ platform, Standard of Care Physical Therapy
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of Cincinnati
Shoulder Arthroplasty, Shoulder Joint Disease
Radiographic and Clinical Outcomes After Short-Stem Reverse Shoulder Arthroplasty
Reverse total shoulder arthroplasty (RTSA) has become increasingly common in recent years due to expanding indications and improved surgical techniques.
- Conditions
- Shoulder Arthroplasty, Shoulder Joint Disease, Reverse Shoulder Prosthesis
- Trial name
- STEP2yrs (NCT07651215)
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Krankenhaus Barmherzige Schwestern Linz
Cuff Tear Arthropathy, Osteoarthritis With Cuff Deficiency
Long-term Clinical Effectiveness of the Delta Xtend Reverse Total Shoulder
This post-marketing study is designed to collect data relating to the use of the Delta Xtend™ Total Shoulder Replacement System in shoulder with rotator cuff deficiencies.
- Conditions
- Cuff Tear Arthropathy, Osteoarthritis With Cuff Deficiency, Rheumatoid Arthritis, Post Traumatic Injury to Shoulder
- Trial name
- NCT00737087
- Testing
- Delta Xtend Reverse Total Shoulder
- Where
- 5 sites in Belgium, France and 1 more
- Volunteers
- 144 people
- Sponsor
- DePuy International
Total Shoulder Arthroplasty, Glenohumeral Osteoarthritis
A Retrospective Review of FloSeal Use in Total Shoulder Arthroplasty
The proposed study aims to objectively assess 2-year clinical and radiographic results for the rate of glenoid component loosening in total shoulder arthroplasty (TSA).
- Trial name
- NCT01726972
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Western Orthopaedics Research and Education Foundation
Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty
Continuous Interscalene Blocks and Rebound Pain
The primary objectives of this present study are to examine whether a continuous interscalene block of a total duration of 48 hours reduces the incidence of rebound pain comparatively to single-shot interscalene block, through…
- Conditions
- Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty, Interscalene Analgesia, Interscalene Blocks
- Trial name
- NCT07770165
- Testing
- Continuous interscalene nerve block, Interscalene Block
- Where
- Canada
- Volunteers
- 154 people
- Sponsor
- University of Calgary
Arthritis
S.E.S Shoulder Arthroplasty Data Collection
This observational study intends to collect efficacy and safety data on S.E.S shoulder system
- Trial name
- NCT00754416
- Where
- 12 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Total Shoulder Arthroplasty
Patient Specific Instruments Versus Standard Surgical Instruments
Comparison of Glenoid Component Position Using Patient Specific Instruments Versus Standard Surgical Instruments: A Randomized Prospective Clinical Trial
- Trial name
- TIOSO-GPS (NCT01430468)
- Testing
- Glenoid Positioning System
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The Cleveland Clinic
Pain, Shoulder
Continuous Interscalene Block for Same Day Discharge Following Total Shoulder Arthroplasty
Total shoulder surgeries are associated with considerable postoperative pain which may prevent rehabilitation and early discharge from the hospital.
- Trial name
- NCT01785940
- Testing
- Interscalene block
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis
Electromyography Evaluation of Subscapularis Function After Total Shoulder Arthroplasty
The primary objective is to document function of the structurally intact subscapularis after total shoulder arthroplasty by using electromyography. Structural integrity of the subscapularis will be confirmed using ultrasound.
- Trial name
- NCT00779974
- Testing
- Evaluation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Milton S. Hershey Medical Center
Arthroplasty, Replacement, Shoulder
S-33 SMR Shoulder HP Reverse Glenosphere
Study Design: Single arm, retrospective and prospective, single center, post-market clinical study Purpose:To demonstrate the safety and effectiveness of the SMR Reverse HP Shoulder System device for primary, fracture or revision…
- Trial name
- NCT05339815
- Testing
- SMR shoulder arthroplasty
- Where
- United Kingdom
- Volunteers
- 205 people
- Sponsor
- Limacorporate S.p.a
Shoulder Fractures, Shoulder Arthritis
Zimmer Biomet Shoulder Arthroplasty PMCF
The objectives of this study are to confirm the safety, performance, and clinical benefits of Zimmer Biomet Shoulder Arthroplasty Systems and its instrumentation in primary or revision shoulder arthroplasty.
- Conditions
- Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity
- Trial name
- NCT04984291
- Testing
- Alliance Glenoid, Identity Stem
- Where
- 17 sites in United States, Japan and 1 more
- Volunteers
- 584 people
- Sponsor
- Zimmer Biomet