Clinical trials: Arthroplasty
Surgical Approach, Hip Arthropathy
SuperPath Versus Posterior Approach for THA
The SuperPATH approach is a minimally invasive approach for total hip arthroplasty. This project randomized patients to the SuperPath versus posterior approach.
- Trial name
- NCT05147207
- Testing
- Superpath Approach
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Dr. Gavin Wood
Osteoarthritis
Inpatient vs Outpatient Total Hip Replacement
This study is a pragmatic randomized clinical trial comparing standard inpatient total hip arthroplasty with same day discharge.
- Trial name
- NCT03026764
- Testing
- Outpatient, Inpatient
- Where
- Canada
- Volunteers
- 558 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Displaced Fracture Neck Femur, Total Hip Arthroplasty (THA)
Total Hip Arthroplasty Versus Bipolar Hemiarthroplasty for Treatment of Intracapsular Displaced Fracture Neck Femur in Elderly Active Patients
Femoral neck fracture (FNF) is a worldwide health problem that can cause significant morbidity and mortality. Most femoral neck fractures are associated with a fall, and the risk factors include osteoporosis, chronic medication…
- Conditions
- Displaced Fracture Neck Femur, Total Hip Arthroplasty (THA), Bipolar Hemiarthroplasty, Elderly Active Patients
- Trial name
- NCT07409909
- Testing
- Total Hip Arthroplasty, Bipolar Hemiarthroplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Knee Arthroplasty, Total
Functional Impact at 12 Months Post-op of Posterior Cruciate Ligament Conservation During Robotic-assisted Surgery (MAKO) for Total Knee Replacement.
Studies have been made on the best way to do knee surgery and whether to conserve the posterior cruciate ligament or not during total knee prosthesis insertion is still under debate.
- Trial name
- LCPTG (NCT07489963)
- Testing
- Total knee arthroplasty
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Arthroplasty, Replacement, Knee
Intraoperative Posterior Cruciate Ligament (Transcruciate) Injection After Total Knee Arthroplasty (TKA)
his study is being done because total knee replacements can leave patients with considerable pain after surgery. Therefore, many studies have been done to find the best ways to control knee pain after the surgery.
- Trial name
- NCT01345604
- Testing
- transcruciate injection of 20cc of normal saline, transcruciate injection of 20 cc of 0.5% Ropivacaine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Saskatchewan
Total Hip Arthroplasty (THA)
Comparison of Blood Loss Between Cemented and Uncemented Femoral Stems in Anterior Total Hip Arthroplasty
Total hip arthroplasty (THA) yields excellent results. To perform the procedure, the surgeon must make certain decisions, including the choice of fixation method for the femoral implant.
- Trial name
- FEMFIX (NCT07492212)
- Testing
- Total hip replacement with cemented fixation, Total hip replacement with non-cemented fixation
- Where
- 2 sites in France
- Volunteers
- 86 people
- Sponsor
- Clinique du Pré
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Total Knee Arthroplasty
A Study Using Metaphyseal Cones Versus a Cemented Stem Construct in Revision TKR
Lay Person's Summary: Knee replacement surgery has been successfully carried out for many years. However, in time, some knee replacements will fail-usually either because of wear or loosening of the replacement parts.
- Trial name
- NCT03169634
- Testing
- short or long stemmed rTKR cemented, Cone with short stem, Cone with long stem
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Knee Osteoarthritis, Total Knee Arthroplasty
Comparison of TKAs Using Force Plate Analysis
The purpose of this study is to evaluate performance of two modern total knee arthroplasty designs using patient reported outcomes and force exhibited during various activities of daily living.
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Knee Injuries, Knee Arthritis
- Trial name
- NCT04163445
- Testing
- MicroPort Orthopedics EVOLUTION Medial Pivot TKA, Depuy Synthes ATTUNE PCR TKA
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Russell Nevins, M.D.
Total Knee Replacement Surgery
Adductor Canal Catheter Effectiveness and Safety Study
PRIMARY OBJECTIVE: Compare the effect of usual care with an adductor canal catheter (ACC) containing ropivacaine to the effect of usual care without an ACC on the second-postoperative-day pain levels among patients undergoing…
- Trial name
- ACCESS (NCT04639128)
- Testing
- Adductor Canal Catheter
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Kaiser Permanente
Osteoarthritis
Comparison of Anesthetic Techniques on Total Hip Arthroplasty
To compare analgesia and orthopedic rehabilitation milestones in patients receiving either spinal anesthesia (local anesthetic plus opioid) or general endotracheal anesthesia with lumbar plexus block.
- Trial name
- NCT01359865
- Testing
- Lumbar Plexus Block
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Postoperative Pain
Catheter-based Peripheral Regional Anesthesia After Total Knee Arthroplasty
BACKGROUND Total knee arthroplasty can be severely painful, and peripheral regional anesthesia is highly recommended as part of the perioperative pain treatment.
- Trial name
- API-KNEE (NCT03372265)
- Testing
- Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- Nordsjaellands Hospital
Shoulder Osteoarthritis, Shoulder Arthritis
AETOS Shoulder System
The goal of this study is to confirm the safety and performance of the AETOS Shoulder System for USA adoption. This is a prospective, open, adaptive, non-comparative, multi-centre investigation enrolling a maximum of 220 subjects…
- Trial name
- NCT06319911
- Testing
- AETOS
- Where
- 5 sites in United States
- Volunteers
- 220 people
- Sponsor
- Smith & Nephew, Inc.
Total Hip Arthroplasty
The Clinical Outcomes After Direct Anterior Approach and Microposterior Approach for Total Hip Arthroplasty
Background The direct anterior approach (DAA) and micro-posterior approach (micro-PA) for total hip arthroplasty (THA) become popular approaches due to their fast recovery and good clinical outcomes.
- Trial name
- NCT03210844
- Testing
- Surgical approaches of total hip arthroplasty
- Where
- Taiwan
- Volunteers
- 141 people
- Sponsor
- National Taiwan University Hospital
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Sleep Patterns After Total Joint Replacement Surgery
The purpose of this study is to determine sleep patterns and sleep quality following total joint arthroplasty, in order to understand when patients should expect to return to baseline or improved sleep following total joint…
- Trial name
- NCT04896892
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Arthroplasty, Replacement, Knee, Nerve Block
Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty
The purpose of this study is to further investigate the efficacy of adductor canal nerve blocks for pain management after total knee replacement.
- Trial name
- NCT02121392
- Testing
- Adductor Canal Nerve Block Catheter, Bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Arthroplasty, Replacement, Knee
Diagnostic Knee Needle Arthroscopy in Predicting Unicompartmental Knee Osteoarthritis
Plain radiographs and MRI play an important role in the diagnosis of intra-articular knee pathology and can be used to guide treatment decisions.
- Trial name
- NCT05002387
- Testing
- NanoScope™ Operative Arthroscopy (Arthrex, Inc)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Albany Medical College
Postoperative Delirium
Electroacupuncture for Preventing Postoperative Delirium in Older Adults Undergoing Total Knee Arthroplasty
Electroacupuncture may improve cognitive function and altered consciousness, but its effect on postoperative delirium in older arthroplasty patients remains unexplored.
- Trial name
- NCT06564506
- Testing
- Disposable acupuncture needles (0.30 × 75 mm), SDZ-V electroacupuncture devices
- Where
- China
- Volunteers
- 1,460 people
- Sponsor
- Fujian Provincial Hospital
Osteoarthritis
DePuy Attune Total Knee Arthroplasty RSA Study
The DePuy Attune knee system incorporates several key features aimed at improving kinematics of the knee joint, range of motion, and smoothness of use compared to existing total knee replacement technologies.
- Trial name
- NCT02103504
- Testing
- DePuy Attune posterior stabilized fixed bearing total knee replacement
- Where
- 3 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Michael Dunbar
Osteoarthritis (OA) of the Knee, Knee Pain Arthritis
Imageless Navigation Versus Image-Based Navigation in Robotic-Assisted Total Knee Arthroplasty for Knee Osteoarthritis
The goal of this clinical trial is to learn if imageless navigation is not inferior to image-based navigation in robotic-assisted total knee arthroplasty (RA-TKA) for treating patients with knee osteoarthritis.
- Conditions
- Osteoarthritis (OA) of the Knee, Knee Pain Arthritis, Total Knee Arthroplasty (TKA), Robotic Assisted Arthroplasty
- Trial name
- NCT07522489
- Testing
- Imageless Robotic-Assisted Total Knee Arthroplasty, Image-based Robotic-Assisted Total Knee Arthroplasty
- Where
- Poland
- Volunteers
- 146 people
- Sponsor
- Medical University of Warsaw