Clinical trials: Arthroplasty
Reverse Total Shoulder Arthroplasty, Physical Therapy
Study of Zimmer Biomet Mymobility Application on Reverse Total Shoulder Arthroplasty (RTSA) Outcomes
This is a trial comparing self-directed rehabilitation using the Zimmer Biomet mymobility digital platform versus standard office-based physical therapy after reverse shoulder replacement.
- Trial name
- NCT05789784
- Testing
- mymobility Physical Therapy, Standard Office-based Physical Therapy
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Campbell Clinic
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement
Brief Summary The goal of this clinical trial is to learn if nurse-led telehealth consultations can help detect complications and support recovery after total knee replacement surgery.
- Trial name
- NCT07058623
- Testing
- Nurse-Led Telehealth Consultation, Traditional In-Person Nursing Consultation
- Where
- Hong Kong
- Volunteers
- 98 people
- Sponsor
- Hospital Authority, Hong Kong
Humeral Fracture, Aged Patient
Comparison Between Anterior Approach (Deltopectoral) and Lateral Approach (Deltoid Splitting) in Shoulder Reverse Arthroplasty for Proximal Humerus Fracture
The aim of the study consists in comparing two surgical approaches (deltopectoral versus lateral deltoid splitting) in the treatment of proximal humerus fractures treated with a reversed total shoulder arthroplasty The assessment…
- Conditions
- Humeral Fracture, Aged Patient, Reversed Total Shoulder Arthroplasty, Surgical Approach
- Trial name
- DELTOSUPEX (NCT03694457)
- Testing
- Reversed total shoulder arthroplasty, lateral approach
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
Arthroplasties, Knee Replacement, Nerve Block
Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine
Revision total knee arthroplasty (rTKA) is a frequently performed procedure. Adequate pain management is an important feature, especially for fast-track and Enhanced Recovery After Surgery (ERAS) programs.
- Conditions
- Arthroplasties, Knee Replacement, Nerve Block, Urinary Retention Postoperative, Anesthesia, Spinal
- Trial name
- POURRKA (NCT07050277)
- Testing
- Intrathecal Morphine, No Intrathecal Morphine
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Osteoarthritis, Hip, Coxarthrosis; Primary
Osseointegration of THA Grafted by PolyNASS (ACTISURF-CERAFIT® ) Versus Non-grafted THA (CERAFIT®)
The infection rate after Total Hip Arthroplasty (THA) is about 1%. It is a serious condition, with high morbidity, sometimes fatal, requiring costly treatment.
- Conditions
- Osteoarthritis, Hip, Coxarthrosis; Primary, Coxarthrosis; Secondary, Osteonecrosis; Aseptic, Idiopathic
- Trial name
- NCT03113981
- Testing
- Total Hip Arthroplasty
- Where
- 7 sites in France
- Volunteers
- 340 people
- Sponsor
- Societe ACTIVBIOMAT
Auriculotherapy, Arthroplasty, Replacement, Knee
The Role of Auricular Point Diagnosis and Treatment in ERAS During TKA
To further improve the surgical outcomes of patients undergoing total knee arthroplasty (TKA). This study aims to use ear acupoint therapy to address the following clinical issues: 1 The degree of postoperative inflammation and…
- Conditions
- Auriculotherapy, Arthroplasty, Replacement, Knee, Enhanced Recovery After Surgery
- Trial name
- NCT06273488
- Testing
- Auriculotherapy
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Peking Union Medical College
Total Knee Arthroplasty, Knee Replacement
Investigating Patient Satisfaction With Smart Knee Implants
The main goal of this study is to see if there is a connection between the social and economic resources available in a patient's neighborhood (measured by the Area Deprivation Index, ADI) and their recovery after knee…
- Conditions
- Total Knee Arthroplasty, Knee Replacement, Knee Replacement Arthroplasty, Knee Osteoarthritis
- Trial name
- NCT06968143
- Testing
- Smart Knee Implant
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Knee Arthroplasty
Effectiveness, Satisfaction, and Usability of Virtual Reality in the Management of Postoperative Pain in Patients Undergoing Knee Arthroplasty
The goal of this clinical trial is to evaluate the effectiveness of using virtual reality glasses to reduce the need for rescue analgesia in patients with acute postoperative pain after knee arthroplasty.
- Trial name
- NCT07286084
- Testing
- VIRTUAL REALITY
- Volunteers
- 45 people
- Sponsor
- Universidad Francisco de Vitoria
Knee Arthroplasty
Efficacy of Proprioceptive Neuromuscular Facilitation Exercise Programme in Patients With Total Knee Arthroplasty
This study was planned to investigate the effectiveness of usual care and proprioceptive neuromuscular facilitation exercise program in patients undergoing total knee arthroplasty surgery.
- Trial name
- NCT05999864
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Muğla Sıtkı Koçman University
Knee Arthroplasty
Effectiveness of Relaxation Methods in Total Knee Arthroplasty Patients
In this study, the effectiveness of a comprehensive training program consisting of pain management, relaxation, breathing, massage and falling components will be investigated in patients with total knee arthroplasty.
- Trial name
- NCT06009341
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Muğla Sıtkı Koçman University
Hip Arthroplasty
Efficacy of Proprioceptive Neuromuscular Facilitation Exercise Program in Total Hip Arthroplasty
This study was planned to investigate the effectiveness of usual care and additional proprioceptive neuromuscular facilitation exercise program in patients undergoing total hip arthroplasty surgery.
- Trial name
- NCT06009432
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Muğla Sıtkı Koçman University
Total Knee Arthroplasty
Study on BT-114143 Reducing Perioperative Bleeding in Total Knee Arthroplasty（TKA）
This is a randomized, double-blind, active-controlled, multicenter, phase II clinical study designed to evaluate the efficacy and safety of BT-114143 Injection in the perioperative treatment of unilateral total knee arthroplasty.
- Trial name
- TKA (NCT07127042)
- Testing
- Low-dose BT-114143, High-dose BT-14143, Tranexamic Acid (IV)
- Where
- China
- Volunteers
- 270 people
- Sponsor
- ScinnoHub Pharmaceutical Co., Ltd.
Total Knee Arthroplasty
Effect of Emotional Freedom Technique on Postoperative Pain and Anxiety in Patients Undergoing Total Knee Replacement
The purpose of the present study was to examine the effects of the Emotional Freedom Technique on pain and anxiety in the postoperative period of patients who underwent total knee arthroplasty.
- Trial name
- NCT05541666
- Testing
- Emotional Freedom Technique (EFT)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ataturk University
Total Hip Arthroplasty (THA), Kinesiophobia
Preoperative Video-Based Education in Total Hip Arthroplasty
This single-center, prospective, randomized controlled trial aims to evaluate the effect of preoperative video-based mobilization education on postoperative fear of movement (kinesiophobia), pain during first mobilization, and…
- Conditions
- Total Hip Arthroplasty (THA), Kinesiophobia, Postoperative Pain, Early Mobilization
- Trial name
- NCT07279974
- Testing
- Video-Based Mobilization Education, Standard Verbal Education
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Acibadem University
Osteoarthritis, Knee, Total Knee Arthroplasty
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
This is a prospective randomized controlled trial that will assess preoperative, perioperative, and long-term oxidative stress (OS); pain; and functional outcomes over a 12 month period and test the hypothesis that a potent…
- Conditions
- Osteoarthritis, Knee, Total Knee Arthroplasty, Chronic Postsurgical Pain
- Trial name
- NCT06083480
- Testing
- GlyNAC (combination of glycine and n-acetylcysteine)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Vanderbilt University Medical Center
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Tranexamic Acid Dosing for Major Joint Replacement Surgery
Over 1.7 million hip and knee replacements are performed every year worldwide. These surgeries are associated with high blood loss and transfusion rates. In older patients, the high blood loss can result in postoperative anemia.
- Trial name
- TXA-Dosing (NCT05075200)
- Testing
- Tranexamic acid
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Sunnybrook Health Sciences Centre
Arthroplasty Complications
Long-term Outcomes of Complex Conversion Total Hip Arthroplasty
The purpose of the research study is to examine the long-term outcomes of complex and conversion total hip arthroplasty procedures.
- Trial name
- LOCC (NCT06533020)
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of North Carolina, Chapel Hill
Postoperative Pain, Acute, Hemodynamics
Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients
In total knee arthroplasty (TKA), the use of a tourniquet and controlled hypotension is common. However, ischemia-reperfusion injury induced by the tourniquet and inappropriate controlled hypotension can lead to cardiac and…
- Conditions
- Postoperative Pain, Acute, Hemodynamics, Total Knee Arthroplasty (TKA)
- Trial name
- TKA (NCT07271849)
- Testing
- Nalbuphine Hydrochloride injection was administered during anesthesia induction., Nalbuphine Hydrochloride injection was administered after cement implantation., Standard general anesthesia regimen ( nalbuphine was not administered throughout the entire anesthesia process.)
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Qianfoshan Hospital
Total Hip Arthroplasty (THA)
Impact of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Elective Hip Replacement
In the present project, the framework conditions of outpatient rehabilitation at the Bonn Center for Outpatient Rehabilitation will now be used to prove whether sports science-controlled strength and BFR training has a similar…
- Trial name
- NCT07043127
- Testing
- BFR
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Arthroplasty
Mineral Nano Pathology
Hip arthroplasty is a treatment widely used in most inflammatory, traumatic and degenerative conditions of this joint. The longevity of implants may be disappointing in some cases, despite the promising results obtained during in…
- Trial name
- MINAPUIH (NCT03898531)
- Testing
- hip prosthesis removed metal / polyethylene, simple mobility, hip prosthesis removed metal / polyethylene, double mobility, hip prosthesis removed ceramic/ polyethylene, simple mobility
- Where
- 2 sites in France
- Volunteers
- 55 people
- Sponsor
- Hospices Civils de Lyon