Clinical trials: Arthroplasty
Osteoarthritis, Avascular Necrosis
A Clinical Evaluation of Metal Ion Release From Metal-on-Metal Cementless Total Hip Arthroplasty
A clinical Evaluation to determine metal ion release from 4th generation metal-on-metal hip articulating surfaces in cementless total hip arthroplasty.
- Conditions
- Osteoarthritis, Avascular Necrosis, Traumatic Arthritis, Rheumatoid Arthritis
- Trial name
- NCT00757354
- Testing
- Metal on Metal cementless hip
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
RSA Study of Persona TKA With CR vs MC Polyethylene
The aim of this study is to evaluate, over a 2 year period, the migration pattern, function and the possibility of anatomical reconstruction of a relatively new total knee arthroplasty (TKA) concept, the Persona.
- Trial name
- NCT03494348
- Testing
- Medial Congruent Polyethylene (MC)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Pain Management, Sedation
The Effect of Continuous Femoral Nerve Block With Modulation of Depth of Anesthesia on Prognosis of Patients Receiving Total Knee Arthroplasty
The interaction of analgesia and sedation ot their effect on the prognosis of surgical patients still need to be elucidated.Currently, how to optimize intra-operative Analgesia and sedation to improve the prognosis of surgical…
- Conditions
- Pain Management, Sedation, Peripheral Nerve Block, Total Knee Arthroplasty
- Trial name
- NCT02576015
- Testing
- peri-operative continuous femoral nerve block with light sedation, post-operative continuous femoral nerve block, lidocaine
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Min Su
Thumb Osteoarthritis
Postoperative Therapy After Interposition Arthroplasty in CMC1
In this randomized controlled trial the investigators want to investigate whether early versus late mobilisation after surgery in the first carpometacarpal joint (CMC1) leads to a faster recovery of hand function.
- Trial name
- NCT01679717
- Testing
- Early mobilisation after CMC1-surgery
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Diakonhjemmet Hospital
Opioid Tolerance, Opioid Naive, Opioid Exposure
Opioid Induced Loss of Local Anesthetic Potency in Patients Undergoing Total Knee Arthroplasty
Peripheral nerve blocks with local anesthetics (LAs) have become an integral part of postoperative pain management particularly for patients undergoing major limb procedures such as such as Total Knee Arthroplasty (TKA).
- Trial name
- NCT03294174
- Testing
- Ropivacaine injection
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Pittsburgh
Trigger Point Pain, Myofascial
Trigger Point Injection in Reducing Pain Following Total Knee Arthroplasty
This study will evaluate the ability of trigger point injections completed immediately following a total knee arthroplasty decrease pain scores and opioid use compared to sham injections.
- Trial name
- NCT06955923
- Testing
- Trigger point injection (lidocaine)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- David Grant U.S. Air Force Medical Center
Arthroplasty, Replacement, Shoulder
Testosterone Levels and Cutibacterium
Phase 1: In 51 patients undergoing shoulder arthroplasties, total serum testosterone, free testosterone and sex hormone binding globulin levels obtained in the clinic before surgery were correlated with the levels of…
- Trial name
- NCT05030220
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Washington
Osteoarthritis, Rheumatoid Arthritis
Minimally Invasive Versus Conventional Approaches in Navigated Total Knee Arthroplasty (TKA)
50 patients are randomized to two groups who receive a navigated knee prosthesis. Aim of the study is a comparison between a minimally invasive and a conventional approach.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis
- Trial name
- NCT00839020
- Testing
- Navigated TKA with a minimally invasive approach, Navigated TKA with a conventional approach
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Aesculap AG
Knee Replacement
Transcranial Direct Current Stimulation for Postoperative Pain in Knee Arthroplasty
The objective of this study is to detect the effect of trans-cranial direct current stimulation on postoperative pain and opioid consumption in total knee arthro-plasty patients.
- Trial name
- TDCSTKA (NCT02704182)
- Testing
- tDCS
- Volunteers
- 46 people
- Sponsor
- Assiut University
Hip Arthropathy
A Randomized Controlled Trial for Patients Underwent Total Hip Arthroplasties Assisted by Surgical Navigation System
This is a randomized controlled, multicenter study. According to the inclusion criteria, volunteers were recruited from patients undergoing total hip arthroplasty.
- Trial name
- NCT04711720
- Testing
- "VTS" surgical navigation system
- Volunteers
- 124 people
- Sponsor
- Peking University Third Hospital
Knee Osteoarthritis
ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty
This study will compare two regional anesthesia strategies for pain management after total knee arthroplasty in adults. Both strategies use an adductor canal block (ACB) to provide analgesia while preserving quadriceps muscle…
- Trial name
- NCT07288970
- Testing
- Adductor Canal Block, Sacral Erector Spinae Plane Block, iPACK Block
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Medical Sciences
Nerve Block
Nerve Blocks With Dexamethasone and Local Anaesthetic to Improve Postoperative Analgesia
Can the association of dexamethasone to the local anaesthetic in a single-shot femoral and sciatic nerve block improve analgesia postoperatively in patients submitted to total knee arthroplasty? Primary aim: Evaluate the efficacy…
- Trial name
- NCT02436694
- Testing
- Local Anesthetic ropivacaíne, Perineural Dexamethasone
- Where
- Portugal
- Volunteers
- 56 people
- Sponsor
- Centro Hospitalar do Porto
Knee Disease, Nerve Pain
Triple Injection Peri-sartorius (TIPS) Block
Comparison between the pain scores after total knee arthroplasty in patients receiving triple injection peri-sartorius (TIPS) block versus femoral nerve block (FNB)
- Trial name
- NCT05289427
- Testing
- ultrasound guided triple injection peri-sartorius block, Femoral Nerve Block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Osteoarthritis, Knee
A Pilot Feasibility Study of IM OXT on Fear of Pain and Trust in Physical Therapist During OP Rehabilitation After TKA
This study will examine the effect that a dose of intramuscular (IM) oxytocin (naturally occurring hormone) has on fear of pain and movement and trust in the physical therapist during outpatient rehabilitation after total knee…
- Trial name
- NCT04493229
- Testing
- Oxytocin
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis, Knee
Vanguard TKA With KneeAlign 2 and Without KneeAlign 2
Purpose of this study is to determine the effectiveness of the KneeAlign 2 system in terms of precise implant alignment by demonstrating that KneeAlign 2 provides better tibial alignment compared to conventional instruments
- Trial name
- NCT02695329
- Testing
- KneeAlign 2
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Total Ankle Arthroplasty Surviviorship
Survival, Clinical and Radiological Outcomes of Total Ankle Arthroplasty With Lateral Transfibular Approach With a Minimum 10 Years Follow up
Ankle osteoarthritis is a disabling condition that can significantly impair patients' quality of life. Ankle arthrodesis has historically represented the gold standard for treating this condition [2], but technological…
- Trial name
- ZTM10 (NCT07732153)
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Postoperative Complications, Postoperative Pain
Suprainguinal Fascia Iliaca Block Versus PENG Block for Hip Arthroplasty Analgesia
In recent years, suprainguinal fascia iliaca block (SFIB) has emerged as a reliable analgesic option for primary total hip arthroplasty (THA).
- Conditions
- Postoperative Complications, Postoperative Pain, Weakness, Muscle, Motor Activity
- Trial name
- NCT04402450
- Testing
- Ultrasound-guided suprainguinal fascia iliaca nerve block, Ultrasound-guided pericapsular nerves group of the hip block
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- University of Chile
Total Hip Arthroplasty (THA), Postoperative Pain Management After Total Hip Arthroplasty
MRI-Based Assessment of Local Anesthetic Spread in the PENG Block Compartment
This study uses MRI imaging to evaluate the spread of local anesthetic following the administration of a pericapsular nerve group (PENG) block.
- Trial name
- MRI-PENG (NCT07040423)
- Testing
- PENG Block, Magnetic resonance imaging
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Campus Bio-Medico University
Arthroplasty Complications, Arthroplasty, Replacement, Knee
Kinesiotape for Edema After Bilateral Total Knee Arthroplasty
The purpose of this study is to determine if kinesiotaping for edema management will decrease post-operative edema in patients with bilateral total knee arthroplasty.
- Trial name
- NCT05013879
- Testing
- Kinesio(R)Tape for edema control
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Montefiore Medical Center
Arthroplasty Complications, Pain, Postoperative
The Effectiveness of High-intensity Laser Therapy on Post-surgical Rehabilitation After Total Knee Arthroplasty
This randomized controlled trial aims to evaluate the effectiveness of high-intensity laser therapy (HILT) as an adjunct to conventional rehabilitation in patients undergoing total knee arthroplasty (TKA).
- Trial name
- NCT07568262
- Testing
- High level laser therapy
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Istituto Ortopedico Rizzoli
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