Clinical trials: Arthroplasty
Knee Injuries and Disorders, Osteo Arthritis Knee
RELIABILITY AND VALIDITY OF THE DT BALANCE TEST IN PATIENTS WITH TKA
The ability to perform a cognitive task while walking simultaneously is essential in real daily life. However, the psychometric properties of dual-task walking tests have not been well established in patients undergoing total…
- Trial name
- DT TKA (NCT06108466)
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Dokuz Eylul University
Pain, Postoperative, Opioid Use
IV vs. Oral Acetaminophen as a Component of Multimodal Analgesia After Total Hip Arthroplasty
The purpose of this study is to determine how well two different methods of administrating Tylenol reduce pain and improve patient satisfaction after total hip replacement (THR) surgery.
- Trial name
- IV Tylenol (NCT03020966)
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Hospital for Special Surgery, New York
Arthropathy of Hip
Supra-inguinal Fascia Iliaca Compartment Block on Postoperative Management in Total Hip Arthroplasty by Posterior Approach
Find the impact of supra-inguinal fascia iliaca compartment block on postoperative pain management after total hip arthroplasty by posterior surgical approach
- Trial name
- NCT04574479
- Testing
- Supra-inguinal fascia iliaca compartment block, Multimodal analgesia and PCA morphine pump
- Where
- Belgium
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Liege
Osteoarthritis, Knee, Arthropathy of Knee
Post-operative Rehabilitation of Total Knee Arthroplasty With Applications on Smart Phone
This study is designed to estimate the effect of an application on rehabilitation for osteoarthritis patients after total knee arthroplasty.
- Trial name
- NCT03365427
- Testing
- APP
- Volunteers
- 200 people
- Sponsor
- Peking University People's Hospital
Osteoarthritis of the Knee
Genicular Radiofrequency Ablation for Unilateral Knee Arthroplasty Pain Management
Three primary reasons prolong hospital stays following unilateral knee arthroplasty. Pain is the primary reason followed by opioid drowsiness and nausea/vomiting side effects.
- Trial name
- RFA (NCT02925442)
- Testing
- t-RFA, C-RFA, Control
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Lyman Medical Research Foundation, Inc.
Arthroplasty, Replacement, Knee, Blood Transfusion, Autologous
A Clinical Study to Investigate if Transfusion of Patients Own Shed Blood Improves the Immunological Status in Comparison to Transfusion of Donor Blood ("Bank Blood")
The primary objective of the study is to compare the immunological status after either autologous blood transfusion as administered by Bellovac® ABT or allogenic blood transfusion, with regards to change in Natural Killer (NK)…
- Conditions
- Arthroplasty, Replacement, Knee, Blood Transfusion, Autologous, Blood Transfusion
- Trial name
- NCT00839241
- Testing
- Bellovac ABT, Allogenic Blood Transfusion
- Where
- Poland
- Volunteers
- 45 people
- Sponsor
- Wellspect HealthCare
Postoperative Pain
Dexamethasone Twice for Pain Treatment of Total Knee Arthroplasty
Dexamethasone twice for pain treatment after total knee arthroplasty - A Placebo-controlled, randomised, parallel 3-group multicentre trial of one and two doses of dexamethasone for postoperative treatment
- Trial name
- DEX-2-TKA (NCT03506789)
- Testing
- Dexamethasone
- Where
- 5 sites in Denmark
- Volunteers
- 485 people
- Sponsor
- Naestved Hospital
Osteo Arthritis Shoulders, Osteoarthritis Shoulder
Endogenous Pain Modulation Study
Rationale: Although most patients experience significant pain relief after total shoulder arthroplasty (TSA), pain persists for some patients even after surgery.
- Trial name
- EPM (NCT05861960)
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Pain, Postoperative
Liposomal Bupivacaine Versus Interscalene Nerve Block
The aim of this study is to compare two different pain management interventions in patients undergoing reverse total shoulder arthroplasty.
- Trial name
- NCT03929146
- Testing
- Exparel, Interscalene Nerve Block
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Osteonecrosis, Osteoarthritis
A Short Metaphyseal Fitting Total Hip Arthroplasty in Young and Elderly Patients
The investigators determined whether 1. new short, metaphyseal-fitting cementless anatomical femoral stem provides major functional improvements 2. radiographically secure implant fixation is achieved with this new stem 3.
- Trial name
- NCT01345097
- Testing
- Total Hip Arthroplasty
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Ewha Womans University
Femoral Neck Fractures
Prospective Randomized Comparison of Bipolar Hemiarthroplasty and Total Hip Arthroplasty With Large Femoral Heads for the Treatment of Displaced Intracapsular Femoral Neck Fractures in the Elderly
The purpose of this study is to compare hemiarthroplasty (HAP) with total hip arthroplasty (THA), performed by trained arthroplasty surgeons with the use of large femoral heads for the treatment of displaced femoral neck…
- Trial name
- NCT01109862
- Testing
- Total hip arthroplasty, Hemiarthroplasty
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Wolfson Medical Center
Femoral Neck Fractures
A Prospective Randomized Trial of Uncemented Versus Cemented Hemiarthroplasty for Displaced Femoral Neck Fractures
There is increasing evidence that primary hemiarthroplasty is the treatment of choice for displaced femoral neck fractures in the elderly No definite conclusions have been made in regards to what kind of arthroplasty is…
- Trial name
- HEMI04 (NCT00491673)
- Testing
- Uncemented primary bipolar hemiarthroplasty of the hip, Cemented primary bipolar hemiarthroplasty of the hip
- Where
- 2 sites in Norway
- Volunteers
- 230 people
- Sponsor
- Ullevaal University Hospital
End-stage Ankle Arthritis (ESAA), Osteoarthritis (OA)
Comparing Ankle Fusion to Ankle Replacement
End-stage ankle arthritis (ESAA) is a debilitating condition associated with severe pain, dysfunction, and reduced quality of life.
- Trial name
- NCT01620541
- Testing
- Ankle Arthrodesis, Ankle Arthroplasty
- Where
- 6 sites in United States
- Volunteers
- 517 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Total Knee Arthroplasty
Medrol Dosepak for Outpatient Total Knee Arthroplasty
The purpose of this study is to evaluate the efficacy of an oral methylprednisolone taper on acute postoperative pain, function, opioid consumption, nausea, and complications following outpatient total knee arthroplasty (TKA).
- Trial name
- NCT05097976
- Testing
- Methylprednisolone
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Total Knee Arthroplasty, Total Knee Replacement
Using Mobilization Exercises on Total Knee Arthroplasty Rehabilitation
There is no definite evidence about the most effective treatment approach in early-stage rehabilitation after total knee arthroplasty surgery.
- Trial name
- NCT03215160
- Testing
- Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University
Proximal Humeral Fracture, Reverse Total Shoulder Arthroplasty
Duration of Immobilization After Reverse Total Arthroplasty for Proximal Humerus Fractures
The purpose of this study is to evaluate compare postoperative range of motion in patients who are given a sling for comfort only and allowed to start early active range of motion compared to patients who are placed in a sling…
- Trial name
- NCT06133920
- Testing
- Early Range of Motion, Immobilization
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cooper Health System
Osteoarthritis, Care Model
The Effect of Continuous Care Counseling Based on the Roy Adaptation Model on Comfort and Quality of Life in Patients Undergoing Total Knee Arthroplasty
Osteoarthritis is a common joint disease that leads to problems such as pain, restricted mobility, and decreased quality of life in the knee joint, especially among elderly individuals.
- Conditions
- Osteoarthritis, Care Model, Quality of Life, Nursing Interventions
- Trial name
- RAM-TKA (NCT07015879)
- Testing
- Continuous Care Counseling Based on the Roy Adaptation Model
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cyprus International University
Hip Arthroplasty Replacement, Post Operative Analgesia
Comparison of Pericapsular Nerve Group (PENG) Block With a Combined Femoral, Sciatic, Lateral Femoral Cutaneous Nerve Block for Postoperative Analgesia in Secondary Total Hip Arthroplasty; (REVPET)
The aim of this clinical trial is to compare the analgesic effect of a pericapsular nerve group (PENG) block with a combined femoral, sciatic, lateral femoral cutaneous nerve block for postoperative analgesia in patients…
- Conditions
- Hip Arthroplasty Replacement, Post Operative Analgesia, Post Operative Pain, Acute
- Trial name
- REVPET (NCT07109388)
- Testing
- Pericapsular nerve group (PENG) block with 0.75% ropivacaine guided by ultrasound, Femoral, sciatic and lateral femoral cutaneous nerve block with 0.375% ropivacaine
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Osteoarthritis
Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation
The general hypothesis is that in older adults muscle regrowth after an acute musculoskeletal stress will be positively influenced by traditional physical rehabilitation, and further enhanced by nutritional supplementation.
- Trial name
- NCT00760383
- Testing
- Essential amino acids, Alanine
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Primary Total Hip Arthroplasty
Clinical Observation Study of the Hydroxylapatite-coated SLPLUS™MIA Hip Shaft
Summary from initial protocol Goal: Validation of the HA (hydroxylapatite) coated SLPLUS ™ MIA stem within an observation study Study design: prospective, multicenter, observational, noncomparative study Study population: 300…
- Trial name
- SL-Plus HA MIA (NCT04036071)
- Testing
- Total Hip Arthroplasty
- Where
- 3 sites in Austria
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Smith & Nephew Orthopaedics AG
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