Clinical trials: Arthroplasty
Total Hip Arthroplasty
Spinal Anesthesia in Total Hip Arthroplasty
Spinal anesthesia is commonly used in patients undergoing total hip replacements. The purpose of this study is to compare lidocaine to bupivacaine spinal anesthesia in patients having a total hip arthroplasty (THA).
- Trial name
- NCT02818894
- Testing
- Lidocaine, Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- Thomas L Bradbury
Total Knee Anthroplasty, Genicular Nerves Block
Efficacy of Genicular Block on Total Knee Arthroplasty Surgery
This prospective, randomized, double-blind, placebo-controlled trial evaluated the analgesic efficacy of preoperative ultrasound-guided genicular nerve block (GNB) in patients undergoing total knee arthroplasty.
- Trial name
- NCT06942702
- Testing
- Genicular blocks (bupivakain), Paracetamol (acetaminophen)+diclofenac, Patient Control Analgesia (PCA) Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Mersin University
Arthroplasty, Replacement, Knee
Randomised Total Knee Arthroplasty With Attune S+ or NexGen CR
The primary purpose of this study is to evaluate the clinical performance of the Attune S+ knee primarily based on evaluation with use of Oxford Knee Score. The NexGen TKR will be used as reference standard.
- Trial name
- NexGe (NCT05464641)
- Testing
- Oxford knee score
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Göteborg University
Orthopedic Disorder
Effect of Preoperative Education Based on Roy Adaptation Model
This research was conducted as a randomized controlled experiment to determine the effect of the education given by the Physiological Mode of Roy Adaptation Model in patients with hip or knee arthroplasty on physical adaptation…
- Trial name
- NCT05248529
- Testing
- Education booklet
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Surgery, Knee Osteoarthritis
Bypass PACU in Knee and Hip Arthroplasty
A Quality Study in the use of Post-Anaesthesia Care Unit(PACU) in Hip and Knee Arthroplasty, and the ability to bypass this unit.
- Conditions
- Surgery, Knee Osteoarthritis, Postoperative Complications, Hip Osteoarthritis
- Trial name
- NCT03984942
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Niklas Ingemann Nielsen
Neuropathic Pain
Does Duloxetine Reduce Chronic Pain After Total Knee Arthroplasty?
Range from 24% to 44%, with a prevalence of neuropathic-type pain from 6% to 20%-cause impairment in quality of life and functional capacity after total knee arthroplasty(TKA).
- Trial name
- NCT02307305
- Testing
- Duloxetine, celecoxib, naproxen/esomeprazole, acetaminophen/tramadol, oxycodone/naloxone
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Hanyang University Seoul Hospital
Arthroplasty, Replacement
sACB vs cACB in TKA
This study compares the analgesic efficacy of single-dose adductor canal block (sACB) versus continuous-dose adductor canal block (cACB) for postoperative pain management in total knee replacement patients.
- Conditions
- Arthroplasty, Replacement, Knee
- Trial name
- NCT07581886
- Testing
- Continuous ACB, Single-shot ACB
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Tranexamic Acid, Arthroplasty, Replacement, Knee
Prevention of Bleeding in Total Joint Replacement: Combined Route Administration of Tranexamic Acid
The investigators aimed to compare two doses of intravenous (IV) tranexamic acid (TXA) with a combined single dose of topical and IV TXA on haemoglobin decline 24 hours after total joint arthroplasties.
- Conditions
- Tranexamic Acid, Arthroplasty, Replacement, Knee, Blood Transfusion, Arthroplasty, Replacement, Hip
- Trial name
- NCT05874583
- Testing
- Combined route administration of Tranexamic acid, Intravenous route Tranexamic acid injection
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- Mongi Slim Hospital
Osteoarthritis
A Comparison of Fixation Method in Total Knee Arthroplasty - Low Viscosity Versus High Viscosity Bone Cement
The purpose of this study is to compare the early migration and periprosthetic bone changes of two total knee arthroplasties fixated with two different type bone cement.
- Trial name
- NCT00175162
- Testing
- Osteopal G vs. Refobacin-Palacos R bone cement
- Where
- Denmark
- Sponsor
- University of Aarhus
Total Hip Arthroplasty
A Hemodynamic Comparison of Stationary and Portable Pneumatic Compression Devices
We are comparing two pneumatic compression devices, VenaFlow (stationary) and MCS (portable) in both the supine an standing position.
- Trial name
- NCT02345642
- Testing
- ActiveCare+SFT Supine, VenaFlow Elite Supine, ActiveCare+SFT Standing
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Knee Arthroplasty
Zip Arthroplasty Patient Satisfaction Evaluation
This study is a prospective, randomized, single center, study to evaluate Zip Closure Device in subjects undergoing knee arthroplasty.
- Trial name
- ZAPS (NCT03178266)
- Testing
- Knee Arthroplasty
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- ZipLine Medical Inc.
Contact Allergic Dermatitis, Adverse Skin Reaction
Aquacel Hypersensitivity Dressing in TJAs
The aim of this multi-surgeon, single institution study is to prospectively evaluate the incidence of allergic contact dermatitis (ACD) following application of AQUACEL Ag, a silver-containing hydrofiber dressing, in total hip…
- Trial name
- NCT06011629
- Testing
- Aquacel dressing
- Where
- United States
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Osteoarthritis, Hip
Dual Energy X-ray Absorptiometry (DXA) Comparison Hip Resurfacing Versus Total Hip Arthroplasty (THA)
This study compares the change (loss) of bone mineral density (BMD) that occurs in the proximal femur after hip resurfacing and total hip replacement.
- Trial name
- NCT01359527
- Testing
- Hip Resurfacing, Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Spokane Joint Replacement Center
Psychological Predictors
An Evaluation of Psychological Parameters That May Influence the Outcome Following Arthroscopy and Arthroplasty for Temporomandibular Joint Surgery
All patients undergoing arthroscopy or arthroplasty for temporomandibular joint dysfunction will complete a psychological questionnaire prior to surgery.
- Trial name
- NCT01396694
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Emory University
Analgesia, Arthropathy of Knee
Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty
The objective of this clinical trial is to compare two regional analgesia techniques in patients undergoing total knee arthroplasty: IPACK (Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee) vs…
- Conditions
- Analgesia, Arthropathy of Knee, Postoperative Pain
- Trial name
- PIPACK (NCT06179641)
- Testing
- Selective tibial nerve block, IPACK block
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Chronic Pain, Opioid Use
Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty
The goal of this interventional clinical trial is to assess opioid consumption 24-48 hrs post anesthesia block among patients undergoing total knee arthroplasty. The main question it aims to answer is: 1.
- Conditions
- Chronic Pain, Opioid Use, Adductor Canal Block, Total Knee Arthroplasty
- Trial name
- NCT05981105
- Testing
- ambIT pump with catheter
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Hospital for Special Surgery, New York
Shoulder Arthritis, Patient Education
Preoperative Rehabilitation and Education Program
Shoulder problems affect many Canadians yearly. While surgery is one of the best treatments for shoulder problems, patients are unaware about shoulder replacement surgeries, the exercises needed after surgery and how to safely…
- Conditions
- Shoulder Arthritis, Patient Education, Prehabilitation, Shoulder Arthroplasty
- Trial name
- PREPS (NCT05965986)
- Testing
- Experimental: PREPS only, Experimental: PREPS and therapy
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis
Bandgrip vs Traditional Sutures TJA
Total Joint Arthroplasty (TJA) has become one of the most performed elective procedures. While the results of this procedure are often consistent with high patient satisfaction and return-to-function, wound-related complications…
- Trial name
- NCT05166642
- Testing
- Bandgrip Micro-Anchor Wound Closure, Suture closure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Center for Innovation and Research Organization
Persistent Postsurgical Pain, Arthritis Knee
Weight Change and the Risk of Chronic Pain Following Hip and Knee Arthroplasties
The study is a nationwide, register-based cohort survey study. The objective of this study is to investigate whether weight change is associated with the incidence of persistent postoperative pain following total hip arthroplasty…
- Conditions
- Persistent Postsurgical Pain, Arthritis Knee, Arthropathy of Knee, Arthropathy of Hip
- Trial name
- NCT06024161
- Testing
- Weight gain, Weight loss, Weight unchanged
- Volunteers
- 6,400 people
- Sponsor
- Bispebjerg Hospital
Post-Operative Pain
Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.
The purpose of this phase 2 study is to evaluate the efficacy and safety of an analgesic drug candidate, VVZ-149 Injections. The study is designed as randomized, double-blind, parallel, and placebo-controlled study.
- Trial name
- NCT03347266
- Testing
- VVZ-149 injections
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Vivozon, Inc.
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