Clinical trials: Arthroplasty
Total Elbow Arthroplasty
Uncemented Total Elbow Arthroplasty Data Collection
The purpose of this study is to document the performance and clinical outcomes of uncemented total elbow replacements involving the press-fit technique performed at the Vanderbilt Hand Center.
- Trial name
- NCT00974298
- Testing
- Total elbow replacement arthroplasty
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Vanderbilt University
Femoral Neck Fracture
Minimal Invasive Anterior Approach Versus Trans-gluteal Approach for Hemi-arthroplasty in Femoral Neck Fractures
The aim of the study is to test the hypothesis that patients older than 60 years with a femoral neck fracture eligible for hemi-arthroplasty (HA) operated by an anterior minimal-invasive approach as compared to a standard lateral…
- Trial name
- MIS-CLAS (NCT01408693)
- Testing
- Trans-gluteal approach, CLAS, Anterior minimal invasive approach, AMIS
- Where
- Switzerland
- Volunteers
- 190 people
- Sponsor
- University Hospital, Basel, Switzerland
Osteoarthritis of the Shoulder
TSA vs RSA in Glenohumeral Osteoarthritis
This study will compare total shoulder arthroplasty (TSA) reverse shoulder arthroplasty (RSA) procedures, in the context of a prospective, randomized-controlled trial to determine the optimal treatment in patients 65 years of age…
- Trial name
- SERVASA (NCT04228419)
- Testing
- Total Shoulder Arthroplasty, Reverse Shoulder Arthroplasty
- Where
- 4 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Ottawa Hospital Research Institute
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Improvement of Patient Satisfaction and Clinical Outcomes Using JointCOACH
JointCOACH is a web-based communication platform that enables joint replacement patients to communicate with their care team via computer or smartphone throughout their episode of care, from the time that surgery is scheduled…
- Trial name
- NCT03499028
- Testing
- JointCOACH
- Where
- United States
- Volunteers
- 446 people
- Sponsor
- The Cleveland Clinic
Arthroplasty, Replacement, Knee, Total Knee Replacement
Metal Ion Concentrations After Total Knee Arthroplasty
The purpose of this study is to analyze the metal ion concentrations in the patients blood following robotic-assisted total knee arthroplasty (TKA) compared to conventional total knee arthroplasty using cutting guides.
- Conditions
- Arthroplasty, Replacement, Knee, Total Knee Replacement, Blood Metal Ion Concentration
- Trial name
- NCT06447922
- Testing
- Metal ion level testing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteo Arthritis Shoulders, Proximal Humeral Fracture
Reverse Total Shoulder Arthroplasty: A Data Analysis on Patients Undergoing Reverse Total Shoulder Arthroplasty
The purpose of this study is to evaluate reverse total shoulder arthroplasty patients preoperative objective measurements and operative objective measurements to determine if there is any effect to postoperative outcomes.
- Conditions
- Osteo Arthritis Shoulders, Proximal Humeral Fracture, Rotator Cuff Tear, Rotator Cuff Tear Arthropathy
- Trial name
- rTSA (NCT03617107)
- Testing
- reverse total shoulder arthroplasty
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Orthopaedic Research & Innovation Foundation
Osteoarthritis of the Knee, Traumatic Arthritis of the Knee
Long-Term Multicenter Evaluation of the E1® Tibial Bearing
This study has been designed to document the long-term outcome of the E1® Tibial Bearings used with the Vanguard® Knee System in 500 patients receiving total knee arthroplasty.
- Trial name
- NCT01374230
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
Hypotension, Ischemia
Phase III Study of Hemospan® for Treating Hypotension in Hip Arthroplasty
The purpose of this study is to determine whether Hemospan is superior to Voluven for treatment of hypotensive episodes during the perioperative period (from induction of spinal anesthesia until 6 hours after skin closure), and…
- Trial name
- NCT00420277
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- 22 sites in Belgium, Czechia and 3 more
- Volunteers
- 462 people
- Sponsor
- Sangart
Hip Disease
A Rehabilitation With Virtual Reality in Patients After Hip Arthroplasty Surgery (VRRS2018)
.Assessing efficacy of rehabilitation with virtual reality exercises compared to traditional rehabilitation in the patient's operated hip arthroplasty
- Trial name
- VRRS2018 (NCT05001100)
- Testing
- rehabilitation
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Prosthetic-joint Infection
A Second Trial of the Abbreviated Protocol Two-Stage Exchange
Apex-2 is a multi-site, parallel group, randomized trial. Patients will be randomly assigned in a 1:1 ratio to the Experimental Arm or the Control Arm.
- Trial name
- Apex-2 (NCT05607030)
- Testing
- VT-X7 Treatment System, Two-stage exchange arthroplasty, SOC Antibiotics
- Where
- 19 sites in United States
- Volunteers
- 76 people
- Sponsor
- Osteal Therapeutics, Inc.
Arthropathy of Knee
Effect of Preoperative Steroid in Total Knee Arthroplasty
Detect the effect of preoperative steroid injection in total knee arthroplasty on post operative: 1. pain 2. oedema 3. nausea and vomiting 4. quadriceps power 5. knee flexion 6. wound complications
- Trial name
- NCT04084912
- Testing
- Dexamethasone Sodium Phosphate, Saline Solution
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Assiut University
Orthopedic Disorder, Arthropathy of Knee
Study to Reduce Sitting in Older Adults Undergoing Hip or Knee Replacements
The aim of this study is to investigate the feasibility of an intervention to reduce sedentary behaviour in older adults waiting for hip and knee replacements.
- Conditions
- Orthopedic Disorder, Arthropathy of Knee, Arthropathy of Hip, Sedentary Lifestyle
- Trial name
- INTEREST (NCT03740412)
- Testing
- Sedentary behaviour reduction using motivational interviewing, education, individualised feedback, goal-setting, self-monitoring, environmental modification, and supportive phone calls
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Birmingham
Postoperative Pain
Local Infiltration Analgesia With Ropivacaine Versus Placebo in Bilateral Knee Arthroplasty
The purpose of this study is to examine whether local infiltration analgesia (LIA) with Ropivacaine and adrenaline is effective in the treatment of postoperative pain after total knee arthroplasty.
- Trial name
- NCT00408707
- Testing
- local infiltration analgesia
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Hvidovre University Hospital
DVT - Deep Vein Thrombosis, PE - Pulmonary Thromboembolism
Outcomes Study in Patients Receiving Aspirin With Mechanical Compression Devices Versus Aspirin Alone Following Knee and Hip Arthroplasty
The Purpose is to compare the safety and efficacy of the use of aspirin(ASA) with medical compression devices versus aspirin alone for venous thromboprophylaxis following knee and hip arthroplasty.
- Trial name
- PDAS (NCT03027167)
- Testing
- Aspirin, (Post- discharge) Mechanical Compression Device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hip and Knee Joint Osteoarthritis, Hip and Knee Joint Arthroplasty
Effectiveness of Exercise Programs Following Total Hip and Knee Joint Arthroplasty
The purpose of the study was to evaluate the effectiveness of balance exercises added to typical joint range of motion and muscle strengthening exercises on balance in patients following total hip or knee joint arthroplasty
- Trial name
- NCT01555307
- Testing
- Typical range of motion and muscle strengthening exercises, and balance exercises, Typical group
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis, Knee
Prehabilitation Using Aquatic Exercise
With aging population, total knee arthroplasty is performed with increasing frequency. Although the surgery is successful in general, significant number of patients suffers persistent pain and disability.
- Trial name
- NCT02773745
- Testing
- Aquatic Prehab
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Fracture Neck of Femur, Hip Fracture
Early Functional Outcome of Operative Treatment of Displaced Femoral Neck Fractures in Two Kenyan Orthopaedic Centres
This was a prospective cohort study. The study was conducted in the two hospitals after approval by the KNH/UON ethical committee and the board of management of Kikuyu Mission Hospital.
- Conditions
- Fracture Neck of Femur, Hip Fracture, Femoral Neck Fracture
- Trial name
- NCT04879472
- Testing
- Osteosynthesis
- Volunteers
- 60 people
- Sponsor
- University of Nairobi
Knee Arthroplasty, Total
Evaluation of Walking Analysis After a Total Knee Arthroplasty With Kinematic Alignment Versus Mechanical Alignment
Total knee arthroplasty (TKA) is a treatment for advanced femoro-tibial osteoarthritis. This surgery is justified in case of significant discomfort and failure of medical treatment.
- Trial name
- KneeKG Sphere (NCT04226339)
- Testing
- total knee arthroplasty with a kinetic alignment, total knee arthroplasty with a mechanical alignment
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Hospices Civils de Lyon
Unilateral Primary Osteoarthritis, Left Knee
Benefits of Early Proprioceptive Re-education Without Visual Information After Total Knee Arthroplasty
Osteoarthritis is a common and disabling joint disease, affecting 4.7% of men and 6.6% of women in France. It causes pain and impaired joint mobility, as well as a reduction in proprioception due to damage to intra-articular…
- Trial name
- RAPPEL (NCT06936267)
- Testing
- rehabilitation : eyes closed, rehabilitation : eyes open
- Where
- 2 sites in France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Rouen
Pain, Acute, Hip Arthropathy
Safety of Ibuprofen After Major Orthopaedic Surgeries
Safety of an eight-day treatment with ibuprofen after primary hip and knee arthroplasties.
- Conditions
- Pain, Acute, Hip Arthropathy, Knee Arthropathy, Safety Issues
- Trial name
- PERISAFE (NCT05575700)
- Testing
- Ibuprofen
- Where
- 11 sites in Denmark
- Volunteers
- 2,904 people
- Sponsor
- Naestved Hospital
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