Clinical trials: Arthroplasty
Pain After Total Knee Arthroplasty, Pain, Postoperative
Comparison of BiFeS + ACB and IPACK + ACB Block Combinations for Postoperative Pain After Total Knee Arthroplasty
This prospective observational study will compare the postoperative analgesic efficacy of two multimodal regional anesthesia combinations routinely used after total knee arthroplasty (TKA) performed under spinal anesthesia.
- Conditions
- Pain After Total Knee Arthroplasty, Pain, Postoperative, Arthroplasty, Replacement, Knee
- Trial name
- NCT07231692
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Degenerative Arthritis, Radial Head Fracture
Ascension PyroCarbon Radial Head Study
The proportion of patient successes with the Carbon Modular Radial Head at the 2-year evaluation is no lower than the proportion of patient successes with the Metal Radial Head.
- Conditions
- Degenerative Arthritis, Radial Head Fracture, Rheumatoid Arthritis
- Trial name
- CMRH (NCT02405234)
- Testing
- Carbon Modular Radial Head replacement, Metal Radial Head replacement
- Where
- 4 sites in United States
- Volunteers
- 78 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis, Hip, Osteoarthritis
The Hip Arthroplasty Positioning Improvement Study
The primary objective of this study is to determine whether the Corin Optimised Positioning System (Corin, U.K.) reduces the rate of hip dislocation at one-year post-operatively compared with standard templating in patients…
- Conditions
- Osteoarthritis, Hip, Osteoarthritis, Arthritis, Musculoskeletal Diseases or Conditions
- Trial name
- HAPI (NCT03560063)
- Testing
- Corin Optimised Positioning System, Standard templating
- Where
- United Kingdom
- Volunteers
- 460 people
- Sponsor
- University of Oxford
Blood Loss, Hemoglobin Change
Prospective Investigation of Intra-Articular Tranexamic Acid Use in Elective Hip Arthroplasty
Tranexamic acid (trans-4-aminomethyl cyclohexane carboxylic acid) is an antifibrinolytic substance that chemically belongs to the group of e-carboxylic acids.
- Conditions
- Blood Loss, Hemoglobin Change, Blood Transfusion, Heterotopic Ossification
- Trial name
- NCT06903299
- Testing
- Intra-articular Tranexamic acid application
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Pain, Shoulder
Comparison of Pain Relief After Non Stimulating Interscalene Catheter Placement vs Stimulating Catheter Placement in Total Shoulder Arthroplasty.
1. Interscalene continuous catheter is a very effective way of controlling pain in total shoulder arthroplasty. To ensure proper placement, nerve stimulating catheter is quite often used. 2.
- Conditions
- Pain, Shoulder, Arthroplasty
- Trial name
- NCT01122732
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Chicago
Continuous Local Infiltration Analgesia, Intra-articular Catheter
Intra-Articular Catheter Total Knee Arthroplasty
This is a prospective, randomized clinical trial evaluating three groups. The groups are: Group 1 (Control): Subjects that receive only the existing standard-of-care multimodal pain management protocol and do not receive…
- Conditions
- Continuous Local Infiltration Analgesia, Intra-articular Catheter, Total Knee Arthroplasty
- Trial name
- NCT06580899
- Testing
- Intra-articular catheter, Routine Standard of Care Treatment
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Arthritis
Prospective Study Measuring Clinical Outcomes of Knee Arthroplasty Using the VERASENSE™ Knee System
The primary objectives of this evaluation are: 1) To attempt to refine the current clinical understanding of "balance" 2) To determine if patients with quantifiably balanced knee joints exhibit improved clinical outcomes versus…
- Trial name
- NCT01469299
- Where
- 8 sites in United States
- Volunteers
- 285 people
- Sponsor
- Orthosensor, Inc.
Arthropathy of Knee
Economic and Functional Impact of Peri-Operative Bracing for Primary Total Knee Arthroplasty (TKA)
While bracing has been shown to be beneficial for patients with osteoarthritis (OA) in terms of function and strength, whether these unloader braces are also similarly beneficial after total knee arthroplasty (TKA) surgery needs…
- Trial name
- NCT03260699
- Testing
- OCSI Rehabilitator brace
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The Cleveland Clinic
Arthritis (E.G., Degenerative Joint Disease (DJD), Osteoarthritis, and Rheumatoid Arthritis (RA))
A Prospective, Pre-market, Multi-center Study of Insignia Hip Stem in THA to Determine Implant Survivorship and PROMS.
The purpose of this study is to evaluate the survivorship (revision rates) and patient reported outcomes (PROMs) following implantation of the Insignia hip stem in patients undergoing cementless total hip replacement surgery…
- Trial name
- NCT06108934
- Testing
- Hip stem prosthesis
- Where
- Australia
- Volunteers
- 313 people
- Sponsor
- Stryker Australia Pty Ltd.
Knee Osteoarthritis, Knee Arthritis
Effectiveness of Reduced Frequency Physical Therapy in Total Knee Arthroplasty
Rehabilitation after Total Knee Arthroplasty surgery involves physical therapy services to address limitations in range of motion, strength, and participation in normal daily activities.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Arthropathy
- Trial name
- NCT03302832
- Testing
- Physical Therapy, In-home Exercise Equipment
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Campbell University, Incorporated
Hip Osteoarthritis, Knee Osteoarthritis
Patient-reported Outcome Measures in Patient Underwent Total Hip and Knee Arthroplasty
Registry of Galeazzi Orthopedic Institute: provides for the regular and systematic collection of all data (clinical and some PROMs) obtained from patients undergoing hip and knee arthroplasty to which questionnaires are proposed…
- Conditions
- Hip Osteoarthritis, Knee Osteoarthritis, Prosthesis Survival
- Trial name
- NCT04960098
- Testing
- arthroplasty
- Where
- Italy
- Volunteers
- 5,816 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Osteoarthritis
Synovial Tissue as a Biomarker in the Early Management of Osteoarthritis
Osteoarthritis is a common disease whose prevalence continues to increase. To date, there is no medical treatment that has proven effective, and only symptomatic treatments exist, mainly to reduce pain.
- Trial name
- SYNPA (NCT07473414)
- Testing
- synovial biopsies
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital
Arthritis Knee, Arthroplasty
Robotic Assisted Knee Arthroplasty - Retain the Anterior Cruciate Ligament or Not
The goal of this clinical trial is to compare the function of the knee after retaining or sacrificing the anterior cruciate ligament in robotic assisted knee arthroplasty.
- Conditions
- Arthritis Knee, Arthroplasty, Gait Analysis
- Trial name
- NCT06264999
- Testing
- Journey II CR, Journey II XR
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Total Knee Arthroplasty
Impact of Prehabilitation in Total Knee Replacement
A study comparing the benefits of pre-habilitation exercise to standard care prior to total knee arthroplasy
- Trial name
- NCT01844934
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Allina Health System
Postoperative Pain Management in Total Knee Arthroplasty
Efficacy of an AFCN Proxy Block in Post-TKA Multimodal Pain Management
This randomized controlled trial evaluates the additive effect of Supra-Sartorial Subcutaneous Infiltration (SSSI) when performed in combination with intermittent adductor canal block (iACB) and posterior capsule local…
- Trial name
- NCT07191964
- Testing
- Supra-Sartorial Subcutaneous Infiltration (SSSI), intermittent adductor canal block (iACB), posterior capsule local infiltration analgesia (PC-LIA)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Medical University WanFang Hospital
Postoperative Pain, Hip Arthroplasty
Local Infiltration Analgesia With Ropivacaine Versus Placebo in Bilateral Hip Arthroplasty
High-volume infiltration analgesia may be effective in postoperative pain management following total hip arthroplasty. In this randomized, double-blind trial patients undergoing bilateral hip arthoplasty are randomized to receive…
- Trial name
- NCT00864409
- Testing
- ropivacaine 0,2%, saline.9%
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Hvidovre University Hospital
Total Knee Arthroplasty Secondary to Osteoarthritis
Continuous Saphenous Block Versus Continuous Femoral Block for Total Knee Arthroplasty
Strength of the Quadriceps Muscle is key to recover from Total Knee Arthroplasty. In this study we compare two techniques for pain control after total knee arthroplasty in terms of preserving the motor function (the strength of…
- Trial name
- NCT01250041
- Testing
- continuous femoral nerve block, continuous saphenous nerve block
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Arthroplasty, Replacement
Triathlon Tritanium Cone Augments Outcomes Study
The purpose of this study was to evaluate the success rate of the Triathlon Tritanium Cone Augment with the Triathlon TS Total Knee System at 2 years postoperative, defined as absence of revision of the Femoral Cone Augment or…
- Conditions
- Arthroplasty, Replacement, Knee
- Trial name
- NCT02521103
- Testing
- Triathlon Tritanium Cone Augments
- Where
- 9 sites in United States
- Volunteers
- 254 people
- Sponsor
- Stryker Orthopaedics
Pain Management, Opioid Consumption
Opioid-Sparing Joint Replacement
The goal of this clinical trial is to evaluate whether an opioid-sparing postoperative pain regimen can reduce opioid consumption and maintain effective pain control in adults undergoing anterior total hip arthroplasty for…
- Trial name
- NCT07348627
- Testing
- Oxycodone 5 mg, Multimodal Non-Opioid Analgesia
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Emory University
Total Knee Arthroplasty, Post Operative Analgesia
Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty
Many methods of pain relief have been implemented in an attempt to provide safe and effective analgesia for patients following total knee arthroplasty.
- Trial name
- NCT00677261
- Testing
- Sciatic Nerve Block, Posterior capsule infiltration with local anesthetic
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Sunnybrook Health Sciences Centre