Clinical trials: Arthroplasty
Blood Loss
The Effects of Low-dose Epinephrine Plus Tranexamic Acid on Perioperative Haemostasis and Inflammatory Reaction in Major Surgery
The purpose of this study is to compare the blood loss of intravenous and topical administration of low dose epinephrine plus combined administration of intravenous and topical tranexamic acid for primary total hip arthroplasty.
- Trial name
- NCT02864095
- Testing
- Tranexamic acid (TXA), Epinephrine
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Southwest Hospital, China
Osteoarthritis
A Trial Between the Intra-articular Local Anesthetic Infiltration With Catheter and Interscalene Block With Catheter in Postoperative Analgesia After Shoulder Prosthesis
The control of perioperative pain is necessary to avoid worst surgical suites after shoulder arthroplasty. Interscalene block (ISB) with or without catheter is the gold standard in postoperative analgesia after shoulder…
- Trial name
- LIA (NCT02365181)
- Testing
- intra-articular local anesthetic infiltration, inter-scalene block, Ropivacaine 2 %
- Where
- 5 sites in France
- Volunteers
- 98 people
- Sponsor
- Hospital Ambroise Paré Paris
Venous Thromboembolism, Venous Thromboses
inDividual, Targeted thrombosIS Prophylaxis Versus the Standard 'One Size Fits All' Approach in Patients Undergoing Total hIp or Total kNee replaCemenT
After hip or knee replacement all patients receive a standardized treatment with blood thinners, this medication is called thrombosis prophylaxis.
- Conditions
- Venous Thromboembolism, Venous Thromboses, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- DISTINCT (NCT06581965)
- Testing
- Short duration prophylaxis, Higher intensity and longer duration prophylaxis, Control
- Where
- 13 sites in Netherlands
- Volunteers
- 10,078 people
- Sponsor
- Leiden University Medical Center
Arthritis Knee
Patients With Asymptomatic Hyperuricemia Have Stronger Local Inflammatory Response and Worse Outcome After Total Knee Arthroplasty
We identify all patients who had undergone primary total knee arthroplsty(TKA) from April 1, 2015, to March 30, 2016. Patients are grouped by uric acid level.
- Trial name
- NCT05476367
- Volunteers
- 614 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
The Results of Total Hip Arthroplasty in Crowe Type 4 Dysplastic Hips
The Results of Total Hip Arthroplasty in Crowe Type 4 Hips.
Total hip arthroplasty (THA) performed for developmental dysplasia of the hip (DDH) is a technically difficult procedure with a high complication rate, especially in the presence of completely dislocated hips.
- Trial name
- NCT04834492
- Testing
- Total hip arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Private Ortopedia Hospital, Seyhan Adana
Knee Arthropathy
Adductor Canal Block With Periarticular Injection and IPACK (ACB/PAI/IPACK) Versus Periarticular Injection (PAI)
A comparison of two pain control methods - the combination of Adductor Canal Block (ACB)/Periarticular Injection (PAI)/Infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (IPACK)…
- Trial name
- IPACK (NCT03094663)
- Testing
- Bupivacaine with epinephrine, Methylprednisolone, Cefazolin
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Anthroplasty, Robotic Surgery
Early Clinical and Radiological Outcomes of a Novel Robotic TKA System
This study aimed to evaluate the early clinical and radiological outcomes of robot assisted total knee arthroplasty, and to determine the efficiency and safety of its bone resection and implant positioning of the novel robot…
- Trial name
- RA-TKA (NCT06638047)
- Testing
- robotic-assisted TKA, CI-TKA
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University Third Hospital
Joint Prosthesis; Complications, Infection or Inflammation
Natural Course of Homocysteine After Uneventful Total Joint Arthroplasty
The goal of this observational study is to asses the natural course of blood homocysteine levels in patients who underwent primary total joint arthroplasty surgery.
- Trial name
- NCT05990816
- Testing
- Blood works for homocysteine levels
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Ankle Osteoarthritis
Total Ankle Replacement Using Guides, Expert Versus Trainee
Patient Specific Instrumentation (PSI) is thought to quicken joint arthroplasty surgery by shortening the operation time and improving alignment.
- Trial name
- TARGET (NCT05729958)
- Testing
- CT scan
- Volunteers
- 20 people
- Sponsor
- Centre for Orthopaedic Research Alkmaar
Osteoarthritis, Hip
Evaluation of Functional Rehabilitation in Patients Undergoing Physiotherapy After Total Hip Arthroplasty
This study aims to objectively evaluate the implications of physiotherapeutic rehabilitation in the Assistance Protocol of Total Hip Arthroplasty (THA), by assessing the motor performance and testing the quality of life of…
- Trial name
- Artrhosis (NCT01491048)
- Testing
- THA Physiotherapy, No physiotherapy after THA
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postoperative Pain, Total Knee Replacement
Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) System
The purpose of this study is to gather information about how knee pain changes when small amounts of electricity are delivered to the nerves in the leg.
- Conditions
- Postoperative Pain, Total Knee Replacement, Total Knee Arthroplasty, Partial Knee Replacement
- Trial name
- NCT04341948
- Testing
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Where
- 10 sites in United States
- Volunteers
- 56 people
- Sponsor
- SPR Therapeutics, Inc.
Arthroplasty, Replacement, Hip
Longjohn Amgen Study - Effect of Denosumab...
The overall objective of the proposed study is to quantify bone loss around non-cemented total hip replacement femoral and acetabular components using DEXA analysis in patients receiving Prolia (denosumab) in the first year of…
- Trial name
- EDRPBLFHR (NCT02444585)
- Testing
- Denosumab
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southern California
Knee Arthroplasty
VEGA System® Study in the Total Knee Arthroplasty
This post-market clinical follow-up study intends to investigate long-term functionality of the VEGA System®. The design of the VEGA System® is meant to provide the patient with more knee mobility compared to their pre-operative…
- Trial name
- NCT02944409
- Testing
- total knee prothesis VEGA System
- Where
- 2 sites in France
- Volunteers
- 125 people
- Sponsor
- BBraun Medical SAS
Arthroplasty
ThromboEmbolism Prevention Efficacy and Safety Trial (TEMPEST)
The purpose of this study is to gain additional safety information as well as to determine after the study drug has been given to patients who have undergone total hip replacement surgery, whether the study drug is effective in…
- Trial name
- TEMPEST (NCT00041509)
- Testing
- SB-424323
- Volunteers
- 343 people
- Sponsor
- GlaxoSmithKline
Osteoarthritis, Knee
Functional Knee Phenotypes of Patients Operated on for Total Knee Arthroplasty
The aim of this study was to analyze the coronal alignment of a large population of patients undergoing total knee arthroplasty using a modern classification of the knee phenotypes found in a population of non-osteoarthritic…
- Trial name
- FP-Knee (NCT05380206)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Knee Arthroplasty, Total
The Analgesic Efficacy of Protocol for Primary Total Knee Arthroplasty (TKA)
This is a perspective, randomized, blinded study with a parallel design and an allocation ratio of 1 to 1 for the treatment groups to assess the analgesic efficacy of adding the iPACK (injection between the popliteal artery and…
- Trial name
- NCT03703206
- Testing
- ultrasound guided injection of local anesthetic between the popliteal artery and the capsule of the knee (iPACK)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Pennsylvania
Regional Anesthesia
Evaluation of Postoperative Analgesic Efficacy of Suprainguinal Fascia Iliaca Block
It was aimed to evaluate the postoperative analgesic efficacy of the suprainguinal fascia iliaca block applied in the postoperative period in terms of 24-hour opioid consumption, pain score, additional analgesic need, and side…
- Trial name
- NCT05450211
- Testing
- Low frequency convex probe (ESAOTE Fixed Color Doppler Ultrasonography Device, Italy), Patient controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun Education and Research Hospital
Proximal Humeral Fracture
Perioperative Complications in Reversed Shoulder Arthroplasties
Retrospective observational study of reversed shoulder arthroplasties by proximal humeral fracture. Analysis of preoperative risk factors as well as minor and major complications at the first week, 90 days and 1 year.
- Trial name
- NCT03243409
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Knee Osteoarthritis, Total Knee Arthroplasty Recovery
The Effect of Balance Training Using a Dynamometric Platform in Patients Undergoing Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a common surgery used to treat advanced knee osteoarthritis, especially when other treatments no longer help.
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty Recovery, Postoperative Rehabilitation, Balance Training
- Trial name
- NCT07080814
- Testing
- Tecnobody ProKin Balance Training, Standard rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ankara Etlik City Hospital
Total Knee Arthroplasty (TKA)
VRAS (Velys Robot-Assisted Solution) Operational Excellence Study
The aim of this study is to investigate the differences in process set-up, efficiency, OR team workload, instrument trays and OR financial performance when using the VRAS (Velys Robotic Assisted Solution) of DePuy Synthes…
- Trial name
- NCT06563843
- Testing
- Robotic-assisted TKA, Conventional TKA
- Where
- 10 sites in Austria, Belgium and 6 more
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DEO NV
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