Clinical trials: Arthroplasty
Arthroplasty Complications
Correlation of Intramedullary Pressure and Systemic Inflammatory Parameters in Cemented Femoral Stem
The cemented femoral stem have impact on increase on systemic parameters. Evaluation of the level of histamine, C-reactive protein (CRP) and leukocytes formula, IL1b, TNF alpha, IL6 and the reflection of changes of these…
- Trial name
- NCT04913623
- Testing
- Hip Replacement
- Where
- Kosovo
- Volunteers
- 60 people
- Sponsor
- University Clinical Centre of Kosova
Arthroplasty Complications, Pain, Joint
Efficacy of iPACK After Unilateral TKA
Total knee arthroplasty (TKA) is a common orthopedic procedure associated with severe postoperative pain which may limit patient rehabilitation and hospital discharge.
- Conditions
- Arthroplasty Complications, Pain, Joint, Arthritis Knee, Regional Anesthesia Morbidity
- Trial name
- NCT04565093
- Testing
- iPACK, Periarticular local infiltration analgesia (LIA)
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- King Khalid University Hospital
Arthroplasty, Neurologic Disorder
Implementation of a Rehabilitation Technology in Orthopedic and Neurological Rehabilitation to Increase Therapy Dosage: an Exploratory Study
Rehabilitation technology is more and more implemented in conventional therapy to increase the dosage of therapy and/or increase patient's motivation towards therapy.
- Trial name
- NCT04906681
- Testing
- i-ACT
- Volunteers
- 40 people
- Sponsor
- PXL University College
Ankle Arthroplasty, Prosthesis User
3D X-ray Motion Analysis of Ankle-foot Motion After Total Ankle Arthroplasty
Patients who have had a total ankle joint replacement surgery typically have limited movement in their ankles possibly due to the fact that commonly used ankle joint prosthetic devices only allow limited axes of motion.
- Conditions
- Ankle Arthroplasty, Prosthesis User, Joint Disease
- Trial name
- NCT03575975
- Testing
- Total Ankle Replacement Prosthesis
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Total Knee Arthroplasty
Treatment With Iovera° for Total Knee Arthroplasty (TKA) Post-Operative Pain
This study is designed to investigate whether iovera° treatment prior to TKA decreases cumulative participant opioid use over the course of 6 weeks following TKA while maintaining similar levels of pain relief.
- Trial name
- NCT03327220
- Testing
- iovera°
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Consent Forms, Osteoarthritis, Knee
Development, Piloting and Evaluation of an Evidence-based Informed Consent Form for Total Knee Arthroplasty
Every medical intervention requires informed consent. Informed consent may include comprehensible information about the necessity and kind of the intervention, material risks and consequences or alternative treatments.
- Conditions
- Consent Forms, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- EvAb-Pilot (NCT04669483)
- Testing
- evidence-based informed consent form
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- University of Witten/Herdecke
Total Knee Arthroplasty
Outcomes for Manual Lymphatic Drainage
In this context, the purpose of our study is to investigate the effect of MLD(manual lymphatic drainage) technique applied in addition to the standard postoperative rehabilitation protocol on pain, kinesophobia and quality of…
- Trial name
- NCT04795011
- Testing
- exercise and manual lymphatic drainage, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Selcuk University
Total Knee Arthroplasty
The Health Impact of Mindfulness Based Stress Reduction on Total Knee Arthroplasty
Despite surgical success of total knee arthroplasty (TKA), reports of dissatisfaction and poor outcomes including increased pain, reduced function for daily activities, and compromised psychological health are common.
- Trial name
- NCT03228745
- Testing
- Pre-operative MBSR
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Total Knee Replacement, Total Knee Arthroplasty
Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System
The purpose of this study is to determine if electrical stimulation (small levels of electricity) in addition to the standard of care can safely and effectively reduce pain following total knee replacement more than the standard…
- Conditions
- Total Knee Replacement, Total Knee Arthroplasty, Pain, Postoperative Pain
- Trial name
- NCT03286543
- Testing
- SPRINT Beta System
- Where
- 5 sites in United States
- Volunteers
- 47 people
- Sponsor
- SPR Therapeutics, Inc.
Acute Pain, Total Knee Arthroplasty
Adductor Canal Block in Outpatient Clinic for Pain Control After Knee Arthroplasty
Single-shot Adductor Canal Block in the outpatient clinic is safe, significantly decreased pain and analgesic consumption and may enhance the rehabilitation program
- Trial name
- ACB (NCT04883034)
- Testing
- adductor canal block in outpatient clinic, Analgesics, etoricoxibe
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Tourniquet Hypertension, Intraoperative Hypertension
Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension
The purpose of this prospective randomized double-blind study is to determine if the novel technique of ultrasound guided peri-arterial injection of local anesthetic around the femoral artery decreases ischemic hypertension…
- Conditions
- Tourniquet Hypertension, Intraoperative Hypertension, Total Ankle Arthroplasty, Ankle Fusion
- Trial name
- NCT03390426
- Testing
- Mepivacaine, Perifemoral Injection of Local Anesthetic, Saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University
Arthroplasty, Replacement, Knee
Music Therapy Versus Control for Total Knee Arthroplasty
For millennia, people have listened to and enjoyed music for entertainment, as a distraction from daily troubles, and as a means to relax and relieve stress.
- Trial name
- NCT03569397
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Alabama at Birmingham
Knee Arthroplasty, Total
Effectiveness of a Psychological Intervention in Patients Undergoing Total Knee Arthroplasty
The purpose of this study is to evaluate the effectiveness of a combined Pain Neuroscience Education (PNE) and Hypnosis (HyP) psychological intervention aiming at the control and prevention of pain and promotion of post-surgical…
- Trial name
- PsInTKA (NCT02988947)
- Testing
- PNE+HyP
- Where
- Portugal
- Volunteers
- 2 people
- Sponsor
- University of Minho
Knee Arthroplasty
Community Based Rehabilitation After Knee Arthroplasty
Background The CORKA study was developed in response to a commissioned call by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme for research into a functional home based…
- Trial name
- CORKA (NCT04867772)
- Testing
- Home based rehabilitation
- Volunteers
- 621 people
- Sponsor
- University of Oxford
Sleep, Pain
Sleep Behavior and Rest-activity Circadian Rhythm (RAR) in Hip/Knee Prosthesis
The consequences of chronically insufficient sleep are both behavioral and medical. . Patients who undergo total knee or hip arthroplasty commonly complain of sleep fragmentation after hospitalization The aim of the present study…
- Conditions
- Sleep, Pain, Hospitalization, Arthroplasty Complications
- Trial name
- Sleep&RAR (NCT03572920)
- Testing
- Objective sleep evaluation by actigraphy, Pittsburgh Sleep Quality Index (PSQI)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Revision Total Knee Arthroplasty, Revision Total Hip Arthroplasty
Tranexamic Acid in Revision Total Joint Arthroplasty
To determine the optimal dosing regimen and route of administration of tranexamic acid (TXA) [single dose intravenous (IV), double dose intravenous, intravenous + topical, and oral repeated dosing] to minimize post-operative…
- Conditions
- Revision Total Knee Arthroplasty, Revision Total Hip Arthroplasty, Acute Blood Loss Anemia
- Trial name
- NCT02877381
- Testing
- Revision Total Knee Arthroplasty (TKA), Revision Total Hip Arthroplasty (THA)
- Where
- 3 sites in United States
- Volunteers
- 175 people
- Sponsor
- Rush University Medical Center
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Improvement of Patient Satisfaction and Clinical Outcomes Using JointCOACH
JointCOACH is a web-based communication platform that enables joint replacement patients to communicate with their care team via computer or smartphone throughout their episode of care, from the time that surgery is scheduled…
- Trial name
- NCT03499028
- Testing
- JointCOACH
- Where
- United States
- Volunteers
- 446 people
- Sponsor
- The Cleveland Clinic
Total Knee Arthroplasty
Outcomes of Rotating Platform Versus Mobile Bearing Total Knee Arthroplasty
Patients were randomly assigned to a fixed bearing or rotating platform of two prostheses. A subsequent study (the one retrospectively registering the original study) asked these patients a series of questions from published…
- Trial name
- NCT03731676
- Testing
- Fixed bearing total knee arthroplasty, Rotating platform total knee arthroplasty
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- William Hopkinson
Unicompartmental Knee Arthroplasty
Univation® X Follow-Up Study
The study is designed as a monocentric, prospective, observational, comparative follow-up study based on two previously treated patient groups.
- Trial name
- NCT03201172
- Testing
- Primary Unicompartmental Knee Arthroplasty
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- Aesculap AG
Knee Arthroplasty
Functional Results With Attune Fixed Bearing Posterior Stabilized Knee Arthroplasty (A-16)
Functional results with Attune Fixed Bearing Posterior Stabilized total knee arthroplasty evaluated with KOOS. A prospective longitudinal cohort study with repetitive measurements 6 weeks, 3, 6, 12 and 24 months postoperative.
- Trial name
- NCT02791477
- Testing
- Attune FB PS knee arthroplasty
- Where
- Norway
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Vestre Viken Hospital Trust