Clinical trials: Arthroplasty
Hip Osteoarthritis, Leg Length Discrepancy
An Intelligent Instrument for Improved Leg Length and Hip Offset Accuracy in Total Hip Arthroplasty
Leg length discrepancies following total hip arthroplasty have been associated with nerve palsies, gait abnormalities, and lower back pain.
- Conditions
- Hip Osteoarthritis, Leg Length Discrepancy, Dislocation
- Trial name
- NCT02095093
- Testing
- Intellijoint HIP, Outrigger
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Total Knee Arthroplasty, Osteoarthritis
Kinematic Analysis: Posterior Stabilized, Fixed Bearing Total Knee Arthroplasty With Attune Knee System
A better understanding of knee joint kinematics is important to explain the premature polyethylene wear failures within total knee arthroplasties (TKAs) and to help design a prosthesis that most closely approximates the normal…
- Trial name
- NCT02204748
- Testing
- DePuy Attune posterior stabilizing fixed bearing knee system
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- The University of Tennessee, Knoxville
Arthropathy of Hip Joint, Osteoarthritis, Hip
Opioid Free and Therapy Minimized Advantages Using HANA Table for Total Hip Arthroplasty
To prove that anterior approach total hip arthroplasty using the HANA table can be performed with little, if any, need for opioids using a combination of education, optimized pre op and post op pain protocols and optimized…
- Trial name
- NCT03790306
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- St. Elizabeth Medical Center, Utica, NY
Arthropathy of Hip, Hip Arthropathy
Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block or Wound Infiltration for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Randomized Controlled Trial
This prospective, randomized controlled trial aims to compare two multimodal regional anesthesia strategies for postoperative analgesia in elective total hip arthroplasty (THA) performed via anterior approach.
- Conditions
- Arthropathy of Hip, Hip Arthropathy, Locoregional Anesthesia, Complication of Anesthesia
- Trial name
- Peng_lfcn/WI (NCT07284615)
- Testing
- PENG plus LFCN block, PENG plus WI
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Ospedale Edoardo Bassini
Total Knee Athroplasty
Does PAI Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving ACB & IPACK?
The goal of this clinical trial is to determine whether Periarticular Injection (PAI) alongside Adductor Canal Block (ACB) and Infiltration between the Popliteal Artery and Capsule of the Knee (IPACK) block can decrease…
- Trial name
- NCT04749615
- Testing
- Periarticular Injection (PAI), Saline Control Periarticular Injection (PAI)
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Arthroplasty
Evaluation of Two Surgical Strategies for Robotic Implantation of Total Knee Prostheses (Stryker), Cemented Versus Uncemented
Total knee replacement surgery (TKA) is a treatment for advanced tibial-femoral osteoarthritis. This intervention is justified in case of significant discomfort and failure of medical treatment.
- Trial name
- MAKO CIMENT (NCT04692714)
- Testing
- Knee prosthesis implementation with additional cement, Knee prosthesis implementation without additional cement
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Knee Arthroplasty
Effectiveness, Satisfaction, and Usability of Virtual Reality in the Management of Postoperative Pain in Patients Undergoing Knee Arthroplasty
The goal of this clinical trial is to evaluate the effectiveness of using virtual reality glasses to reduce the need for rescue analgesia in patients with acute postoperative pain after knee arthroplasty.
- Trial name
- NCT07286084
- Testing
- VIRTUAL REALITY
- Volunteers
- 45 people
- Sponsor
- Universidad Francisco de Vitoria
Osteoarthritis
Nurse Led Follow-up After Total Knee Arthroplasty
The aim of this study is to determine the effect of nurse led follow-up following total knee arthroplasty in regard to physical function, health related quality of life and self-efficacy.
- Trial name
- NFTKA (NCT01771315)
- Testing
- Telephone follow-up
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- University of Southern Denmark
Hip Arthroplasty
Hospital for Special Surgery Hip Arthroplasty Cohort
Total joint replacements are some of the most successful medical devices developed over the last fifty years. They enable millions of people to remain ambulatory and pain free, with minimal risk.
- Trial name
- NCT00454506
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Hospital for Special Surgery, New York
Arthroplasty, Replacement
Comparison of Comparison of Ropivacaine and Liposomal Bupivacaine for Total Knee Arthroplasty
This is a randomized prospective outcomes study comparing two groups of patients. One group will receive liposomal bupivacaine for a periarticular injection.
- Conditions
- Arthroplasty, Replacement, Knee
- Trial name
- NCT02616367
- Testing
- liposomal bupivacaine Periarticular injection, Ropivacaine Periarticular Injection
- Sponsor
- University of Minnesota
Periprosthetic Joint Infection (PJI), Malnutitrion
Impact of Nutritional Status Before Joint Replacement on Infection Risk
Periprosthetic joint infection (PJI) is a serious complication after joint replacement surgery and is difficult to treat. Poor nutritional status may impair the body's ability to recover and fight infection, as well as increase…
- Conditions
- Periprosthetic Joint Infection (PJI), Malnutitrion, Postoperative Complication
- Trial name
- CONUT (Control (NCT07884006)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Knee Osteoarthritis, Primary Total Knee Arthroplasty
Evaluation of Utility of Ultrasound Guided iPACK Block for Knee Extension After Total Knee Arthroplasty.
The purpose of this study is to learn if using an Interspace between the Popliteal Artery and Capsule of the Knee (iPACK) injection technique (also called a "nerve block") that numbs the nerves going to the back part of the knee…
- Conditions
- Knee Osteoarthritis, Primary Total Knee Arthroplasty, Physical Therapy, Pain
- Trial name
- NCT03353233
- Testing
- Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Total Joint Arthroplasty
Measuring Postoperative Mobility, Gait Symmetry and Feedback Following TJA
The objectives of this study are: 1. The investigators plan to evaluate and validate the use of a novel wireless insole device (Loadsol) that provides real-time biofeedback on post-operative mobility and weight bearing following…
- Trial name
- NCT03673293
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Utah
Knee Osteoarthritis
Stability of Uncemented Medially Stabilized TKA
Total joint replacement is an efficacious treatment for osteoarthritis of hips and knees. Both total knee replacement (TKR) and total hip replacements (THR) have excellent implant survivorship.
- Trial name
- NCT04017533
- Testing
- GMK Sphere TKR
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Oslo University Hospital
Tranexamic Acid Use, Blood Loss
Tranexamic Acid Use and Blood Loss in Total Hip Arthroplasty
The purpose of this study is to determine the need for a blood transfusion during surgery and to evaluate the levels of certain proteins in the blood when given tranexamic acid.
- Trial name
- NCT02989155
- Where
- United States
- Volunteers
- 576 people
- Sponsor
- Ohio State University
Osteoarthritis
Does Optimal Control of Pre-operative Chronic and Acute Pain Predict Improved Function After Orthopedic Surgery?
Despite the development of new pain medications, the prevalence of persistent postoperative pain (for more than three to six months) remains alarmingly high.
- Trial name
- NCT00581685
- Testing
- Pregabalin, Celecoxib
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Postoperative Pain
The Efficacy of Periarticular Single Drug Compared With Multimodal Drug Injection in Controlling Pain After TKA
The purpose of this study is to determine the periarticular multimodal drug injection has more efficacy for controlling pain after TKA than single anaesthetic drug injection.
- Trial name
- TKA (NCT01898052)
- Testing
- single anaesthetic drug, multimodal drug injection
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Thammasat University
Knee Osteoarthritis
Dexamethasone vs Dexmedetomidine for iPACK + ACB in TKA
This randomized, double-blind, controlled trial is designed to compare the analgesic efficacy and safety of perineural dexamethasone versus perineural dexmedetomidine as adjuvants to ropivacaine for ultrasound-guided interspace…
- Trial name
- NCT07386600
- Testing
- Ropivacaine 0.2% Injectable Solution, Dexamethasone 4mg, Dexmedetomidine
- Where
- Poland
- Volunteers
- 96 people
- Sponsor
- Poznan University of Medical Sciences
Humeral Fracture, Proximal
Comparison of Hemi-shoulder Arthroplasty and PHILOS in Treating Three or Four-part Fractures of Proximal Humerus
To explore clinical effectiveness of PHILOS plate fixation and hemi-shoulder arthroplasty in treating three or four-part fractures of proximal humerus
- Trial name
- NCT03358784
- Testing
- Hemi-shoulder Arthroplasty, PHILOS Plate
- Volunteers
- 300 people
- Sponsor
- Peking University People's Hospital
Pain, Postoperative, Satisfaction
Comparing Ropivacaine Adductor Canal Blockade by Surgeon Versus Anesthesiologist
The purpose of this study is to evaluate the efficacy of two methods of administering an adductor canal block (ACB) following total knee arthroplasty (TKA); intraoperative surgeon performed intra-articular adductor canal block…
- Trial name
- NCT03864588
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Rothman Institute Orthopaedics
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.