Clinical trials: Arthroscopic Surgery
Shoulder Injury
Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery
Pre-operative perineural injection of dexamethasone mixed with local anesthetic in peripheral nerve blockade for orthopedic surgery has been shown to prolong the length of analgesia, improve visual analog pain scores, decrease…
- Trial name
- NCT01450007
- Testing
- Ropivacaine, Dexamethasone, Normal saline
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Mayo Clinic
Arthroscopic Shoulder Surgery, Pain, Postoperative
Examining the Effectiveness of a Connective Tissue Matrix Implant in Reducing Post-operative Pain and Narcotic After Outpatient Arthroscopic Shoulder Surgery
This document is a protocol for a human research study. This study is to be conducted according to United States standards of Good Clinical Practice in accordance with applicable Federal regulations and institutional research…
- Trial name
- ECM (NCT04633837)
- Testing
- Extracellular Matrix Graft Injectable Implant
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brian Badman
Osteoarthritis, Knee
Arthroscopy in the Treatment of Degenerative Medial Meniscus Tear
Degenerative meniscal tears are the most common etiology for knee pain, swelling and loss of function. Partial arthroscopic meniscectomy is the most common orthopaedic procedure to treat meniscal tears.
- Trial name
- NCT00549172
- Testing
- Operative (partial arthroscopy), Conservative (diagnostic arthroscopy)
- Where
- 5 sites in Finland
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Tampere University
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Following Arthroscopic Shoulder Surgery
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing elective arthroscopic shoulder surgery on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993798
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 10 sites in Austria, Germany and 3 more
- Volunteers
- 107 people
- Sponsor
- Durect
Acute Pain
Liposomal Bupivacaine Interscalene Blocks for Rotator Cuff Repair
The purpose of this study is to compare pain control after arthroscopic rotator cuff repair surgery using either liposomal bupivacaine or bupivacaine when injected in an interscalene block.
- Trial name
- RCR (NCT03587584)
- Testing
- liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
Arthroscopic Knee Surgery
Hyperosmolar Saline Irrigation Fluid in Arthroscopic Knee Surgery
An isotonic solution, such as saline (0.9%, 300mOsm/L) or lactated ringer's (273 mOsm/L), is commonly used and safely proven for joint irrigation during arthroscopy.
- Trial name
- Salty Knee (NCT03564886)
- Testing
- Hyperosmolar Saline, Normal saline
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Missouri-Columbia
Meniscus Tear
Effects of TENS Therapy Following Arthroscopic Knee Surgery
Following standard of care procedures for arthroscopy knee surgery it is anticipated that Transcutaneous Electrical Nerve Stimulation (TENS) will provide improved pain relief and improve functional outcomes.
- Trial name
- TENS (NCT01528228)
- Testing
- TENS Treatment with functional or disabled unit
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- A.T. Still University of Health Sciences
Pain
Ear Acupuncture for Pain Associated With Ambulatory Arthroscopic Knee Surgery
The investigators propose to complete a randomized controlled trial to compare ear acupuncture at Cingulate gyrus, thalamus, omega 2, shen-men, and point zero on the right and left ear plus standard of care versus standard of…
- Trial name
- BFAKnee (NCT01447329)
- Testing
- Ear Acupuncture, Standard Treatment
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
Postoperative Pain
Safety and Efficacy of Tapentadol Immediate Release (IR) and Oxycodone IR for Treatment of Acute Post-op Pain Following Elective Arthroscopic (Surgery Using a Thin Flexible Scope) Shoulder Surgery
The purpose of this study is to evaluate how tapentadol immediate release (IR) and oxycodone IR treat moderate to severe post-operative pain after elective arthroscopic shoulder surgery.
- Trial name
- NCT00814580
- Testing
- Tapentadol IR, Oxycodone IR
- Volunteers
- 382 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Osteoarthritis
Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
There are two cartilage structures, called menisci, in each knee joint. A torn meniscus can be caused by a traumatic injury or aging-related degeneration.
- Trial name
- NCT00597012
- Testing
- Arthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
- Where
- 7 sites in United States
- Volunteers
- 351 people
- Sponsor
- Brigham and Women's Hospital
Rotator Cuff Tear, Shoulder Impingement Syndrome
Arthroscopic Rotator Cuff Repair of Full Thickness Tears With and Without Arthroscopic Acromioplasty
Surgical repair of full thickness tears of the rotator cuff is a controversial issue, with several procedures currently being used to treat the tear.
- Trial name
- NCT00290888
- Testing
- Acromioplasty
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- Panam Clinic
Anterior Cruciate Ligament Injury
Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction
This study will examine the potential differences between femoral nerve blockade (FNB) and adductor canal blockade (ACB) for pain control and quadriceps muscle activation for patients following anterior cruciate ligament (ACL)…
- Trial name
- FNB vs ACB (NCT03704376)
- Testing
- 30 ml of 0.2% ropivacaine, 15 ml of 0.2% ropivacaine, 100 mcg clonidine
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- The University of Texas Health Science Center, Houston
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
The purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.
- Trial name
- NCT05190120
- Testing
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Femoroacetabular Impingement
A Physical Therapy Program Versus Surgery for Femoroacetabular Impingement: Randomized Clinical Trial
The purpose of this study is to compare the outcomes for patients that receive two different treatments used for FAI (Femoroacetabular Impingement).
- Trial name
- NCT01993615
- Testing
- Arthroscopic Surgery, Physical Therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Madigan Army Medical Center
Degenerative Meniscal Tear
Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Martina Hansens Hospital Norway, and University of Southern Denmark, Odense, Denmark.
- Trial name
- OMEX (NCT01002794)
- Testing
- Arthroscopic partial menisectomy, Supervised neuromuscular and strength training
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Arthroscopic Knee Surgery
A Pilot Study to Determine the Efficacy of Intravenous Ibuprofen for Pain Control Following Arthroscopic Knee Surgery
The intent of this study is to assess the analgesic efficacy of IV ibuprofen when administered at induction of anesthesia. Results from this pilot study will be used to design and determine the appropriate statistical power for a…
- Trial name
- NCT01650519
- Testing
- IV ibuprofen, IV ketorolac
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Cumberland Pharmaceuticals
Post-operative Pain
Initial Local Anesthetic Dose With Continuous Interscalene Analgesia
Objective: To determine a minimally effective initial local anesthetic bolus required to provide satisfactory analgesia using continuous brachial plexus infusion following arthroscopic shoulder surgery using a double-blind…
- Trial name
- NCT00672100
- Testing
- Ropivacaine
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Corewell Health East
Meniscus Tear, Tibial, Pain, Postoperative
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery
The utilization of arthroscopic surgery to treat meniscus injuries has continued to increase in recent years, partly due to a younger, more active population, and improved technology and technique.
- Conditions
- Meniscus Tear, Tibial, Pain, Postoperative, Postoperative Complications, Ketorolac Adverse Reaction
- Trial name
- NCT04246541
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Shoulder Pain, Rotator Cuff Tear
Efficacy of Interscalene Brachial Plexus Block With Liposomal Bupivacaine for Arthroscopic Shoulder Surgery
The purpose of this study is to compare the quality and duration of pain relief after shoulder surgery provided by a single injection of liposomal bupivacaine versus standard bupivacaine when administered as an interscalene…
- Trial name
- NCT01977352
- Testing
- Liposomal bupivacaine, Bupivacaine 0.25%
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center