Clinical trials: Arthrosis of Hand, active
Hand Surgery, Wrist Surgery
The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery
Patients undergoing hand, wrist, and elbow surgery may experience pain after surgery. The orthopedic surgeon may provide prescription pain medications after surgery to assist with pain control.
- Conditions
- Hand Surgery, Wrist Surgery, Elbow Surgery, Fracture Fixation
- Trial name
- NCT06806410
- Testing
- Liposomal bupivacaine (LB), Dexamethasone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Education, Joint Diseases
The Application of Artificial Intelligence in Wrist and Hand Joint Ultrasound
1. To develop an AI system that can automatically identify standard sections and save images during wrist and hand joint ultrasound scans, while labeling key anatomical structures. 2.
- Trial name
- NCT06883669
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Osteoarthritis Hand, Osteoarthritis Wrist
Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis
The purpose of this research is to compare low-dose radiotherapy to corticosteroid injection for treatment of hand/wrist osteoarthritis.
- Trial name
- NCT07217405
- Testing
- Corticosteroid injection (CSI), Low-dose radiotherapy (LDRT)
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Mayo Clinic
Hand Osteoarthritis
Metformin Treatment of Patients with Hand Osteoarthritis
To compare metformin (2 g daily), or maximum tolerated dose, for 16 weeks with placebo as a treatment of hand osteoarthritis symptoms.
- Trial name
- METRO (NCT06367283)
- Testing
- Metformin
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Marius Henriksen
Osteoarthritis Hand
Use of Allograft Adipose Matrix for Small Joint Arthritis of the Hand
The purpose the research is to evaluate the safety and efficacy of injection of adipose allograft matrix (AAM) to the small joints of the hand for treatment of early stage osteoarthritis.
- Trial name
- NCT05747469
- Testing
- local anaesthetic injection, Human Adipose Allograft
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Osteoarthritis Hand
Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of STT Osteoarthritis
The aim of this open, prospective, multicenter trial is to evaluate the use of a sterile, devitalized, processed umbilical cord amniotic membrane implant placed in joint interposition in the treatment of STT osteoarthritis.
- Trial name
- NCT06038331
- Testing
- SclerFIX-IP
- Where
- 4 sites in France
- Volunteers
- 14 people
- Sponsor
- TBF Genie Tissulaire
Hand Injuries and Disorders, Neurological Conditions
3D Hand Orthosis Trial
In people with chronic hand conditions, hand orthoses are frequently prescribed to improve performance in activities of daily living (ADL).
- Conditions
- Hand Injuries and Disorders, Neurological Conditions, Neuromuscular Diseases (NMD), Musculoskeletal Conditions (e.g., Tendinitis, Capsulitis)
- Trial name
- NCT07633821
- Testing
- 3D-printed hand orthosis (intervention), Conventional hand orthosis (control)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hand Osteoarthritis, Osteoarthritis
Investigation of the Effectiveness of Short Wave Diathermy Treatment in Patients With Hand Osteoarthritis
The aim of this randomized, double-blind, placebo-controlled study was to evaluate the effects of shortwave diathermy therapy on pain, grip strength, and functionality in patients with hand osteoarthritis.
- Trial name
- NCT06739096
- Testing
- Short Wave Diathermy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Omer Sezgin
Osteoarthritis Hand
Efficacy of Surgical Joint Denervation in Painful Digital Osteoarthritis
Digital osteoarthritis is the second localization of symptomatic osteoarthritis, after the knee. Its cardinal symptoms are particularly intense pain and functional impairment in the case of the erosive form.
- Trial name
- DECAD (NCT05378841)
- Testing
- Surgical Denervation
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hand Osteoarthritis, Erosive Osteoarthritis
A 30-month Follow-up of MERINO Participants to Evaluate Long-term Effects of Methotrexate in Erosive Hand OA.
In response to the high prevalence of synovitis in hand osteoarthritis (OA) and its association with pain, there\'s a compelling rationale for investigating the efficacy of MTX in managing inflammatory erosive hand OA.
- Trial name
- MERINO:2 (NCT06281184)
- Testing
- Methotrexate, Treatment as usual
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis, Hand Osteoarthritis
Balneotherapy and Peloid Therapy Impact Small Joint Diseases
This clinical trial investigates the effects of natural healing factors (mineral water and mud procedures) in combination with regular rehabilitation of patients with degenerative small joint disease.
- Conditions
- Osteoarthritis, Hand Osteoarthritis, Foot Osteoarthritis
- Trial name
- NCT06477393
- Testing
- Regular rehababilitation, Heat procedures, Healing mud application
- Where
- 2 sites in Lithuania
- Volunteers
- 130 people
- Sponsor
- Lithuanian University of Health Sciences
Thumb Osteoarthritis
Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Thumb carpometacarpal (CMC) osteoarthritis (OA) is common, seen frequently in middle-aged and elderly women. While a variety of surgical treatments have been described with none superior to any other, there is no consensus on the…
- Trial name
- NCT04828954
- Testing
- Immobilization for 2-weeks postoperative, Immobilization for 6-weeks postoperative
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Chicago
Shoulder Impingement Syndrome
Impact of Core Stability Training on Pain and Function in Patient With Shoulder Impingement Syndrome Among Manual Operated Hand Workers
Even at the early stage of employment exposure to mechanical factors such as lifting heavy weights, working with hands at or above shoulder level, and pushing or pulling heavy loads are independent risk factors for new-onset…
- Trial name
- NCT07237789
- Testing
- Experimental, Control
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hand Osteoarthritis
The Efficacy and Safety of Intramuscular Methylprednisolone in Patients With Hand OsteoArthritis
The goal of this clinical trial is to determine the efficacy and safety of intramuscular methylprednisolone in patients with hand osteoarthritis.
- Trial name
- IMHOA (NCT07371572)
- Testing
- 120mg methylprednisolone acetate, 40mg methylprednisolone acetate
- Where
- Netherlands
- Volunteers
- 212 people
- Sponsor
- Sint Maartenskliniek
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Rheumatoid Arthritis
Neuropathic Hand Pain in Rheumatoid Arthritis
Investigators have aimed to estimate prevalence of neuropathic hand pain in RA patients and it's relation with sleep quality and sensory thresholds. For this purpose a case-control study design was planned.
- Trial name
- NCT04839081
- Testing
- questionnaires and inventories
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Bozyaka Training and Research Hospital
Osteoarthritis
Evaluation of the Safety of LipiodolⓇ Embolization in Symptomatic Digital Osteoarthritis Refractory to Conventional Treatment
The goal of this clinical trial is to evaluate the safety of arterial embolization using Lipiodol® in patients with symptomatic hand osteoarthritis refractory to conventional treatment.
- Trial name
- EMBARDI (NCT06611007)
- Testing
- embolization therapy
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Hand Osteoarthritis
A Prospective Cohort Study of Patients Suffering From Hand Osteoarthritis Symptoms
The late-stage forms of degenerative osteoarthritis (OA) are very debilitating and less affordable to therapy. The main objective is to identify early onset symptoms of hand OA patients through imaging techniques (such as…
- Trial name
- COARDIG (NCT03650673)
- Testing
- Identification of subgroups of patients with early AD with risk of progression
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Hand, Hand Therapy
Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System
This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later.
- Conditions
- Hand, Hand Therapy, Upper Extremity, Prediction Models
- Trial name
- HANDREHPREDICT (NCT07522060)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Arthrosis of Hand
DIGItal Cohort Osteoarthritis Design
Introduction Osteoarthritis is a chronic disease characterized by a progressive degradation of articular cartilage. Hand OA involves symptomatically more than 1 million of subjects in France (i.e., painful or with functional…
- Trial name
- DIGICOD (NCT01831570)
- Testing
- GENETIC and radiographs
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris