Clinical trials: Articular Disease
University Students
Temporomandibular Disorders and Balance Performance
This study aims to investigate the relationship of the temporomandibular joint with head posture, pressure pain threshold, and body balance.
- Trial name
- NCT06891859
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Multiple Sclerosis
Local Vibration and Ankle Mobilization in Multiple Sclerosis
This study will investigate the effects of local vibration and ankle joint mobilization on muscle tone, proprioception, and balance in individuals with multiple sclerosis (MS).
- Trial name
- NCT07879950
- Testing
- Local Vibration, Ankle Joint Mobilization
- Volunteers
- 60 people
- Sponsor
- Gaziantep Islam Science and Technology University
Genu Varum, Genu Valgum
Retrospective Evaluation of Guided Growth Plate System Plus's Safety and Clinical Performance for the Treatment of Lower Limbs Deformities.
Orthofix is conducting this retrospective Post-market clinical follow up (PMCF) study to assess the safety and clinical performance of the Guided Growth Plate System Plus (GGPSP) device, which is a new version of the Guided…
- Conditions
- Genu Varum, Genu Valgum, Joint Diseases, Knee Deformity
- Trial name
- NCT05241691
- Testing
- Guided Growth Plate System Plus
- Where
- Italy
- Volunteers
- 69 people
- Sponsor
- Orthofix s.r.l.
Breast Cancer
Acupuncture for Aromatase Inhibitor Induced Joint Pain
This is a randomized, controlled, pilot study to determine the safety and efficacy of acupuncture as an adjunct to pharmacological treatment compared to pharmacological intervention alone for the treatment of musculoskeletal pain…
- Trial name
- NCT00826397
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Rheumatoid Arthritis
Effect of Butyrate Supplement on Rheumatoid Arthritis
This study is a pilot study to evaluate the safety and efficacy of administering butyrate supplement on rheumatoid arthritis patients. Thirty participants will be included to receive butyrate supplement for 12 weeks.
- Trial name
- NCT05576597
- Testing
- Sodium Butyrate
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University People's Hospital
Shoulder Injuries and Disorders
Usability and Acceptance of a New Robotic Exoskeleton for Shoulder Rehabilitation
The purpose of this pilot study is to validate the safety, reliability and usability of FLOAT medical device, a prototypal robotic system for the rehabilitation of the shoulder, designed and developed in the Rehab Technologies…
- Trial name
- CRMINAIL08 (NCT04758520)
- Testing
- FLOAT upper limb exoskeleton
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Rheumatoid Arthritis
Evaluating the Safety of Extended Treatment With Pegsunercept (PEG sTNF-RI)in Subjects With Rheumatoid Arthritis (RA)
The purpose of this study is to evaluate the safety of an additional 28 weeks of treatment with pegsunercept for subjects who have completed treatment in a previous double-blind study (20000201 or 20000198).
- Trial name
- NCT00111423
- Testing
- Pegsunercept (PEG sTNF-RI)
- Volunteers
- 216 people
- Sponsor
- Amgen
Shoulder Impingement Syndrome
The Combined Effect of Thoracic Manipulation and Instrument-assisted Soft Tissue Mobilization in Patients With Shoulder Impingement Syndrome
This study will be conducted to investigate the combined effect of thoracic manipulation and instrument-assisted soft tissue mobilization in patients with shoulder impingement syndrome
- Trial name
- SIS (NCT07800559)
- Testing
- conventional physical therapy, thoracic manibulation, instrument assisted soft tissue mobilization
- Volunteers
- 80 people
- Sponsor
- Cairo University
Fracture; Pelvic, Insufficiency Fractures
Real World Evidence of SI-BONE's iFuse TORQ TNT Advancing Treatment of Pelvic Ring Fractures
The purpose of this study is to evaluate outcomes in patients treated with iFuse TORQ TNT for pelvic fragility fractures.
- Conditions
- Fracture; Pelvic, Insufficiency Fractures, Fragility Fracture, Sacroiliac; Fusion
- Trial name
- REBAR (NCT07530497)
- Testing
- iFuse TORQ TNT Implant System
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- SI-BONE, Inc.
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Extended Post-operative Oral TXA in Primary THA
The goal of this clinical trial is to learn if extended post-operative oral tranexamic acid (TXA) - a medication that reduces bleeding by slowing the breakdown of blood clots - can improve functional recovery following surgery in…
- Trial name
- NCT07685743
- Testing
- Extended oral tranexamic acid regimen
- Volunteers
- 170 people
- Sponsor
- Oregon Health and Science University
Shoulder Pain, Shoulder Impingement Syndrome
Performance and Safety of LightForce® Therapy Lasers on Shoulder Soft Tissue Inflammation Pain Reduction
DJO UK Ltd (ENOVIS) is conducting this study to assess the effectiveness of LightForce® Therapy Lasers on pain reduction in shoulder soft tissue inflammation.
- Conditions
- Shoulder Pain, Shoulder Impingement Syndrome, Rotator Cuff Tendinitis
- Trial name
- SHINE (NCT06759935)
- Testing
- Laser therapy, physiotherapy/exercise protocol
- Where
- 10 sites in France, Italy and 1 more
- Volunteers
- 104 people
- Sponsor
- DJO UK Ltd
Osteoarthritis
A Multi-Center Study on the Clinical Advantages of Personalized Total Knee Arthroplasty System
The purpose of this study is to evaluate the clinical benefits of personalized total knee arthroplasty (TKA) in comparison with conventional TKA.
- Trial name
- NCT07003035
- Where
- China
- Volunteers
- 80 people
- Sponsor
- YujiakuoTHU
Developmental Dysplasia of Hip
Using Artificial Intelligence to Screen for Hip Dysplasia
The goal of this clinical trial is to learn if an ultrasound scan using artificial intelligence can accurately screen for hip dysplasia.
- Trial name
- NCT06647225
- Testing
- Artificial intelligence augmented ultrasound
- Where
- Australia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Systemic Sclerosis (SSc), Idiopathic Inflammatory Myopathy (IIM)
Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases
A Phase 1 study of HBI0101 BCMA-CART in B-Cell Mediated Autoimmune Rheumatic Diseases. The goal of the study is evaluation of safety and identification of the maximum HBI0101 CART dose that may be administered safely to patients…
- Conditions
- Systemic Sclerosis (SSc), Idiopathic Inflammatory Myopathy (IIM), Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE)
- Trial name
- NCT07085676
- Testing
- HBI0101 CART
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Polina Stepensky
Rheumatoid Arthritis
Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Rheumatoid Arthritis (RA)
This is a two part study comparing CHS-0214 to Enbrel in patients with active rheumatoid arthritis and an inadequate response with Methotrexate (MTX) who are naive to biologic therapies.
- Trial name
- CHS-0214-02 (NCT02115750)
- Testing
- Etanercept, CHS-0214
- Where
- 141 sites in United States, Belarus and 10 more
- Volunteers
- 647 people
- Sponsor
- Coherus Oncology, Inc.
Arthropathy of Knee, Arthritis and/or Post-traumatic Degenerative Problems
Optetrak Posterior Stabilized Versus Optetrak Hi-Flex
The purpose of this study is to evaluate the differences in clinical outcomes between the Optetrak® Posterior Stabilized ("Optetrak® PS", Exactech, Gainesville, FL) and the Optetrak® Hi-Flex™ ("Optetrak® HF", Exactech…
- Trial name
- NCT00808613
- Testing
- Optetrak PS, Optetrak Hi-Flex
- Where
- United States
- Sponsor
- Exactech
Uncontrolled Gout
Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy
This is a Phase 4, multicenter, open-label trial of pegloticase with methotrexate (MTX) in adult participants with uncontrolled gout who were previously treated with pegloticase without a concomitant immunomodulator and stopped…
- Trial name
- NCT04772313
- Testing
- Pegloticase, Methotrexate (MTX)
- Where
- 15 sites in United States
- Volunteers
- 11 people
- Sponsor
- Amgen
Acute Haematogenous Osteomyelitis, Septic Arthritis
Long- and Midterm Outcomes of Osteoarticular Infections in Paediatric Patients
Multi-centre clinical follow-up study on patients with a history of acute haematogenous osteomyelitis and/or septic arthritis. The aim is to describe the frequency of sequelae in these former patients with osteoarticular…
- Trial name
- LOOP (NCT03827980)
- Testing
- no intervention, only clinical examination
- Where
- 2 sites in Switzerland
- Volunteers
- 78 people
- Sponsor
- Prof. Dr. Ulrich Heininger
Disease Activity
14.0- 3.0- 3.0- η Protein With Rheumatoid Arthritis
Aim of work: to explore the potential association between serum 14.0-3.0-3.0- η protein level with disease activity and bone mineral density (BMD) in Egyptian patients with rheumatoid arthritis (RA).
- Trial name
- NCT05366608
- Testing
- Serum level of 14.0- 3.0- 3.0- η protein and IL_.6
- Where
- Egypt
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Osteoarthritis, Knee
Effects of Denosumab on Bone Microarchitecture After Total Knee Arthroplasty
This study evaluates single dose of Denosumab in decreasing systemic and periprosthetic bone resorption after Total Knee Arthroplasty compared to placebo in 60 patients (30 placebo and 30 Denosumab) within 2 months after surgery.
- Trial name
- NCT05559268
- Testing
- Denosumab 60 MG/ML Injectable Solution [Prolia]
- Volunteers
- 60 people
- Sponsor
- The Affiliated Hospital of Qingdao University
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