Clinical trials: Articular Disease
Spondylitis, Ankylosing
Treat-to-Target Strategy With Etanercept for Ankylosing Spondylitis
Evaluate the disease activity guided tapering and discontinuation strategies of etanercept (ETN) in patients with ankylosing spondylitis (AS) in 48 weeks.
- Trial name
- T2TEAS (NCT03880968)
- Testing
- tapering or discontinuation of etanercept
- Volunteers
- 311 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Total Hip Replacement
Efficiency of the Adjustable Lower Extremity Abduction Apparatus After Total Hip Replacement Surgery
This study was conducted to evaluate the effect of the adjustable lower extremity abduction apparatus developed after total hip arthroplasty (TKP) surgeries on preventing dislocation and walking.The study is of randomized…
- Trial name
- NCT06169878
- Testing
- Adjustable lower limb abduction apparatus
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bahçeşehir University
Osteoarthritis, Knee
Protocol for the Clinical Evaluation of Lyophilized Amniotic Fluid in the Treatment of Knee Osteoarthritis
To evaluate the efficacy of Lyophilized amniotic fluid as compared to the Saline Injection, placebo control in the treatment of moderate osteoarthritis of the knee.
- Trial name
- NCT03074526
- Testing
- Amniotic Fluid
- Where
- 4 sites in United States
- Volunteers
- 156 people
- Sponsor
- MiMedx Group, Inc.
Pigmented Villonodular Synovitis, TGCT
A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT
AMB-051-07 is an open-label, adaptive, dose-ranging study with long-term extension in adults with tenosynovial giant cell tumor
- Conditions
- Pigmented Villonodular Synovitis, TGCT, Tenosynovial Giant Cell Tumor
- Trial name
- NCT05349643
- Testing
- AMB-05X
- Where
- 6 sites in United States, Australia and 1 more
- Volunteers
- 20 people
- Sponsor
- AmMax Bio, Inc.
Ankylosing Spondylitis
Etanercept (Enbrel) in Ankylosing Spondylitis
The study has the aim to investigate the efficacy and safety of etanercept in patients with active ankylosing spondylitis (AS) over 520 weeks.
- Trial name
- Enbrel_AS-2 (NCT01289743)
- Testing
- Etanercept
- Where
- 2 sites in Germany
- Volunteers
- 24 people
- Sponsor
- Charite University, Berlin, Germany
Knee Osteoarthritis
Home Based Hip Strengthening for Knee OA Patients
In knee osteoarthritis patients, weakness of hip abductor muscles is considered an important contributing factor leading to the progression of the disease.
- Trial name
- NCT05131048
- Testing
- conventional group, experimental group
- Volunteers
- 90 people
- Sponsor
- University of Lahore
Systemic Lupus Erythematosus, Arthralgia
The Impact of Exercise on Hand Function, Daily Activities Performance and Quality of Life of SLE' Patients
A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria were randomly assigned to the exercise group (n=32) or the control group…
- Trial name
- NCT03802578
- Testing
- HAND EXERCISE
- Where
- 2 sites in Greece
- Volunteers
- 62 people
- Sponsor
- National and Kapodistrian University of Athens
Patellofemoral Pain Syndrome, Knee Pain
5 Year Follow-up of Adolescents With Knee Pain
The prevalence of adolescent knee pain is 33%, and patellofemoral pain (PFP) is the most common diagnosis with a nontraumatic onset. The 5-year prognosis of adolescent PFP compared with other types of knee pain is unknown.
- Trial name
- NCT02873143
- Testing
- No intervention
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Morton Neuroma
Blind and Ultrasound Guided Injection in Morton Neuroma
The aim of this work trial is to compare the effectiveness of blind and ultrasound guided injection for Morton neuroma in order to determine which is more appropriate as the initial procedure in conservative treatment
- Trial name
- NCT03046108
- Testing
- blind injection of Morton neuroma, blind injection of Mepivacaine, blind injection of Triamcinolone
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Complejo Hospitalario Universitario de Granada
Juvenile Idiopathic Arthritis, Hip Arthritis
Hip Denervation in Juvenile Idiopathic Arthritis With Hip Arthritis
Patients having juvenile idiopathic arthritis (according to ILAR criteria) with hip arthritis were divided into 3 groups. Group 1 received hip denervation and group 2 controlled and received a subcutaneous injection of saline…
- Trial name
- NCT04775225
- Testing
- Lidocaine, Steroid
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Sohag University
Arthralgia
Effect of a Specific Hand Intervention in Women With Arthralgia Secondary to Hormone Therapy Following Breast Cancer.
This study aims to evaluate the impact of a 12-week hand exercise program on pain, manual dexterity, and hand function in women experiencing hand joint pain (arthralgia) due to hormone therapy after breast cancer.
- Trial name
- NCT06746376
- Testing
- Occupational Therapy
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Total Knee Arthroplasty, Osteoarthritis
Kinematic and Mechanical Alignment Randomized Trial
Knee replacement surgery is the second most common surgery in Canada. People who have very painful knee arthritis usually receive a knee replacement where the surgeon aims to make everyone's knee as straight as possible (called…
- Trial name
- KMART (NCT06787417)
- Testing
- Restricted Kinematically-aligned Arthroplasty, Mechanically-Aligned Arthroplasty
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- McMaster University
Osteoarthritis (OA)
Comparison of the Pain and Functional Improvement of Combined Extracorporeal Shockwave Therapy With or Without Intra-articular Hyaluronic Acid and Platelet-rich Plasma Injection on Advanced Osteoarthritis of the Knees.
This was a single group, double-blind, randomized clinical trial that enrolled 48 patients with Kellgren-Lawrence grade II to IV osteoarthritis of the knee.
- Trial name
- NCT07819955
- Testing
- Extracorporeal Shock Wave Therapy, Normal Saline, Hyaluronic Acid (HA)
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Rheumatoid Arthritis, Osteoarthritis
Periodontal Disease and P. Gingivalis in Rheumatoid Arthritis
Periodontitis (PD) has been postulated to be a risk factor for the onset and progression of rheumatoid arthritis (RA). Recent reports suggest that infection with Porphyromonas gingivalis (P.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Periodontal Disease
- Trial name
- NCT01156155
- Testing
- Digital xray of jaw and teeth, Blood draw, questionnaires
- Where
- United States
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Axial Spondyloarthritis
A Study Treating Participants With Early Axial Spondyloarthritis (axSpA) Taking an Intense Treatment Approach Versus Routine Treatment
A study comparing a treat-to-target (T2T) intense treatment approach with routine treatment (Standard of Care [SOC]) in reducing disease activity in participants with axial spondyloarthritis (axSpA).
- Trial name
- STRIKE (NCT02897115)
- Testing
- Adalimumab, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
- Volunteers
- 22 people
- Sponsor
- AbbVie
Myofascial Pain - Dysfunction Syndrome of TMJ
Dry Needling Vs Transcutaneous Electrical Nerve Stimulation in Management of Myofascial Pain Dysfunction Syndrome
Myofascial pain dysfunction syndrome (MPDS) is the most common form of temporomandibular disorders. Because of the multifactorial nature of the problem, its management is still not definite.
- Trial name
- NCT06583915
- Testing
- TENS, Dry Needle
- Volunteers
- 26 people
- Sponsor
- Cairo University
Postoperative Anemia, Osteoarthritis, Knee
Comparing Intravenous and Oral Iron in Postoperative Anemia
Postoperative anaemia are common in patients undergoing major orthopaedic surgery. The main consequence of perioperative anaemia is an increased risk of red blood cell (RBC) transfusions.
- Trial name
- NCT01913808
- Testing
- Ferric carboxymaltose, ferrous glycine sulphate
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Parc de Salut Mar
ACL Injury
Multimodal Assessment of Knee Conditions in Rehabilitation
The purpose of this study is to assess ACL injury and other pathological knee conditions from the combination of signals that are known to provide information on the knee joint.
- Trial name
- NCT03608189
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- University of Oulu
Shoulder Dislocation
Does Immobilization of the Shoulder in External Rotation Reduce the Recurrence Rate of Shoulder Dislocation?
Dislocation of the glenohumeral joint is the most common traumatic joint dislocation. The usual treatment of first time traumatic anterior dislocation of the shoulder is reduction followed by immobilization in a sling for a…
- Trial name
- NCT00202735
- Testing
- Arm1:Immobilization in external rotation, immobilization in internal rotation
- Volunteers
- 188 people
- Sponsor
- Sorlandet Hospital HF
Pain, Osteoarthritis
An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain
The purpose of the study is to assess the long-term safety profile of Tapentadol (CG5503) extended release (ER) at dosages ranging from 100 to 250 mg twice a day in treating patients with moderate to severe chronic pain over a…
- Conditions
- Pain, Osteoarthritis, Low Back Pain
- Trial name
- NCT00487435
- Testing
- Tapentadol (CG5503) Extended Release (ER)
- Where
- 148 sites in United States, Australia and 2 more
- Volunteers
- 1,166 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
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