Clinical trials: Articular Disease
Knee Osteoarthritis
Efficacy and Safety of Hymovis ONE® (32mg/4ml) Intrarticular Injection in Active Patients With Knee Overuse Syndrome
The aim of this study is to evaluate the efficacy and safety of Hymovis® ONE (32 mg/4 ml) single intra-articular injection, in the management of pain caused by knee osteochondral lesions.
- Trial name
- NCT04661111
- Testing
- Hymovis® ONE (32 mg/4 ml)
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Osteoarthritis (OA) of the Knee
INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE
The goal of this clinical trial is to evaluate the effectiveness of Neural Ice for pain management associated with knee osteoarthritis in adults aged 22-80 years.
- Trial name
- ICE (NCT06700109)
- Testing
- Neural Ice, Triamcinolone acetate
- Where
- 15 sites in United States
- Volunteers
- 263 people
- Sponsor
- Brixton Biosciences, Inc.
Alkaptonuria
Study of Alkaptonuria
The purpose of this study is to gain a better understanding of alkaptonuria and collect medical data on patients who may later participate in new drug trials for this rare genetic disease.
- Trial name
- NCT00005909
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Knee Arthropathy, Postoperative Pain
Optimization of a Fast-track Concept for Knee Joint Replacement
In an estimated 150,000 patients, a knee joint replacement is performed in Germany every year. The perioperative care of the patients aims at an optimal surgical technique, which leads to a high functionality in the joint, and…
- Conditions
- Knee Arthropathy, Postoperative Pain, Postoperative Complications
- Trial name
- KneeOptOut2 (NCT03920930)
- Testing
- Late local infiltration analgesia, Early local infiltration analgesia
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
Postoperative Pain, Hip Osteoarthritis
Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blocks for Hip Surgery Analgesia
This study aims to investigate the efficacy of adding a Posterior Pericapsular Deep gluteal block to two other standard nerve blocks-the Pericapsular Nerve Group block and the Lateral Femoral Cutaneous Nerve block-for patients…
- Conditions
- Postoperative Pain, Hip Osteoarthritis, Hip Fractures
- Trial name
- NCT07531030
- Testing
- Posterior Pericapsular Deep Gluteal, Pericapsular Nerve Group, and Lateral Femoral Cutaneous Nerve Blocks., Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blocks.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Osteoarthritis Knee
Efficacy and Safety Study of Individualized and Standardized Acupuncture Treatment for Knee Osteoarthritis
The purpose of this study is to verify the efficacy and safety of acupuncture treatments (Individualized, Standardized acupuncture) for patients with knee osteoarthritis (OA).
- Trial name
- NCT01569230
- Testing
- Standardized Acupuncture, Individualized Acupuncture, Waiting
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Eun Jung Kim
Patellofemoral Pain Syndrome
Efficiency of Patellar Taping in Treatment of Patellofemoral Pain Syndrome
Patellar subluxation is a common disorder that may cause patellofemoral pain syndrome. The efficiency of patellar taping in the treatment of patellofemoral pain syndrome has been reported good outcomes in most patients.
- Trial name
- NCT01504100
- Where
- Taiwan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Spondyloarthritis
Comparison of Sodium Fluoride Positron Emission Tomography and Magnetic Resonance Imaging of Spine and Sacroiliac Joints for Detection of Inflammatory Lesions in Spondyloarthritis Patients
The purpose is to compare detection of axial inflammatory lesions in patients affected by spondyloarthritis (SpA) with sodium fluoride positron emission tomography (PET) and magnetic resonance imaging (MRI), the reference…
- Trial name
- FNa (NCT02869100)
- Testing
- Blood sample, Sodium fluoride Positron Emission Tomography, Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Central Hospital, Nancy, France
Knee Osteoarthritis
Digital Motivation to Decrease Inactive Behaviour in Patients With Knee Osteoarthritis
Physical inactivity is a major risk behaviour with a potential for causing premature death, particularly among people with mobility limitations, such as knee osteoarthritis.
- Trial name
- NCT03339011
- Testing
- Motivational SMS text message
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- Marius Henriksen
Osteoarthritis, Knee, Diabete Type 2
Increased Blood Glucose Levels After Steroid Injection
a sample of 600 patients diagnosed as Knee osteoarthritis injected with 40 mg triamcinolone, recorded their morning fasting blood glucose levels for 7 days before injection used as the baseline blood glucose level, which was…
- Trial name
- NCT06228911
- Testing
- steroid (triamcinolone)
- Where
- Syria
- Volunteers
- 600 people
- Sponsor
- Syrian Private University
Knee Osteoarthritis
Effects of KT and Rigid Taping in Knee OA.
The purpose of the study is to compare the effects of kinesio taping and rigid taping in Knee Osteoarthritis to alleviate symptoms like pain, reduce range of motion and functional limitations.
- Trial name
- NCT05946434
- Testing
- Kinesio Tape Group, Rigid Tape Group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Shoulder Pain, Subacromial Pain Syndrome
The Effect of the Treatment Environment on Pain, Function, Self Efficacy and Satisfaction in RCRSP
Brief Summary The aim of this randomized controlled study is to reveal the short-term effects of physical and social factors in different therapeutic environments on patients with rotator cuff related shoulder pain following the…
- Conditions
- Shoulder Pain, Subacromial Pain Syndrome, Rotator Cuff Syndrome of Shoulder and Allied Disorders
- Trial name
- NCT06449534
- Testing
- Patient Education, Exercise Therapy, Cold Application
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Osteoarthritis
Thumb Muscle Thickness and Strength in CMC Osteoarthritis
A total of 34 patients aged between 50-80 years, diagnosed with first carpometacarpal joint osteoarthritis based on hand radiographs taken within the last 3 months, will be included in the study from the Physical Therapy and…
- Trial name
- NCT06730698
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Beylikduzu State Hospital
Chronic Inflammation, Mobility
Effect of Maolactin™ FMR on Exercise Recovery, Inflammation and Muscle Comfort in an Otherwise Healthy Population
This is a double blind, randomised, placebo-controlled, parallel-group trial to evaluate the effect of Maolactin FMR supplementation on chronic inflammation, mobility and muscle and joint pain in an otherwise healthy population…
- Conditions
- Chronic Inflammation, Mobility, Muscle Pain, Joint Pain
- Trial name
- NCT06444763
- Testing
- Maolactin, Maltodextrin
- Where
- Australia
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Rheumatoid Arthritis
Marine Oils and Arthritis
NSAIDS are associated with adverse GI effects and COX-2 inhibitors have cardiovascular risk. Long-term oral supplementation with fish oil reduce e.g.
- Trial name
- NCT00805116
- Testing
- Whale blubber oil, Cod liver oil
- Volunteers
- 7 people
- Sponsor
- National Institute of Nutrition and Seafood Research, Norway
Disorders, Temporomandibular Joint, Range of Motion, Articular
Effectiveness of a Physiotherapy Treatment for Temporomandibular Hyperlaxity
A 14-day physiotherapy treatment for temporomandibular joint hyperlaxity is established. Pre-intervention measurements and intermediate and end-of-treatment measurements are taken.
- Trial name
- NCT04811495
- Testing
- Physiotherapy treatment
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Universidad Católica de Ávila
Healthy Participants Study, Rheumatoid Arthritis
A Phase 1, First-in-Human Study of CND319 in Healthy Participants and Patients With Rheumatic Diseases
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary clinical activity of CND319 in healthy adult participants and patients with rheumatic diseases.
- Conditions
- Healthy Participants Study, Rheumatoid Arthritis, Sjogren's Syndrome
- Trial name
- NCT07712939
- Testing
- CND319
- Where
- Australia
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Candid Therapeutics
Breast Cancer, Breast Cancer Female
Factors Affecting Functionality in Breast Cancer Survivors
Breast cancer is the most frequent cancer type in women globally. In conjunction with the new developments, breast cancer survival has increased therefore the management of long-term complications has gained importance.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Cancer Lymphedema, Breast Carcinoma in Situ
- Trial name
- NCT04245657
- Testing
- Tissue Dielectric Constant Measurement, Muscle strength measurement, Hand-Grip Strength Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Izmir Bakircay University
Spondylitis, Ankylosing
A Study of the Efficacy and Tolerance of Remicade in the Treatment of Active Ankylosing Spondylitis (Study P04042)(COMPLETED)
The objective of this study is to prove reasonability of registration in Russian federation this new indication (ankylosing spondylitis [AS]) through evaluation of safety and efficacy rate of Remicade 5mg/kg, given as an…
- Trial name
- NCT00779012
- Testing
- Infliximab
- Volunteers
- 42 people
- Sponsor
- Merck Sharp & Dohme LLC
Osteoarthritis
A Study to Determine if Aquamin Modulates Inflammatory Biomarkers in the Blood of Osteoarthritis and Healthy Subjects
Osteoarthritis (OA) is the most common kind of arthritis and primarily affects the large, weight bearing joints (including the knees, lower back, hips, neck and the feet) and the joints in the hands.
- Trial name
- NCT01321281
- Testing
- AquaCal, AquaPT
- Where
- Ireland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Andrea Doolan
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