Clinical trials: Articulation Disorders
Dysarthria, Stroke
Non-invasive Brain Stimulation as a Treatment for Dysarthria Post-stroke
The proposed study aimed to determine if tDCS can help post-stroke patients with dysarthria.
- Trial name
- NCT05497362
- Testing
- Real tDCS
- Where
- Hong Kong
- Volunteers
- 9 people
- Sponsor
- The University of Hong Kong
Dystonia, Primary, Dysarthria
Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular
To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement…
- Conditions
- Dystonia, Primary, Dysarthria, Dysphonia, Dysphagia
- Trial name
- DOM (NCT03380676)
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Parkinson's Disease, Dysarthria
A Comparison of Voice Amplifiers and Personal Communication Systems in Individuals With Parkinson's Disease
This study will compare two types of assistive devices for communication (a voice amplifier and a personal communication system) in individuals with a speech disorder related to Parkinson's disease.
- Trial name
- NCT02407067
- Testing
- ChatterVox, Easy Listener FM system (Phonic Ear Corp.)
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Single Sided Deafness, Unilateral Deafness
Cochlear Implants in Young Children With SSD
The goal of this clinical trial is to investigate the safety and effectiveness of cochlear implantation in infants and toddlers with single-sided deafness.
- Conditions
- Single Sided Deafness, Unilateral Deafness, Hearing Loss, Unilateral, Hearing Loss
- Trial name
- Little SSD (NCT05775367)
- Testing
- Cochlear Implant
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Aphasia, Stroke
HD-tDCS for Phonological Impairment in Aphasia
This study will investigate the effects of mild electrical stimulation in conjunction with speech therapy for people with post-stroke aphasia to enhance language recovery.
- Trial name
- NCT06010030
- Testing
- Targeted Transcranial Direct Current Stimulation, Speech Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Medical College of Wisconsin
Amyotrophic Lateral Sclerosis, Neuromuscular Disease
Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
The Connect-One Study is an early feasibility study to obtain preliminary device safety information for the Connexus Brain-Computer Interface (BCI).
- Conditions
- Amyotrophic Lateral Sclerosis, Neuromuscular Disease, Stroke, Tetraplegia/Tetraparesis
- Trial name
- CONNECT-ONE (NCT07357428)
- Testing
- Connexus Brain-Computer Interface
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Paradromics
Speech Articulation Disorder, Developmental Articulation Disorder
Randomized Clinical Trial of Phonological Interventions
Recent research reveals genetic and symptomatic overlap among children with speech sound disorders (i.e., those who (misarticulate more sounds than would be expected for their age) and children with dyslexia (i.e., those who…
- Conditions
- Speech Articulation Disorder, Developmental Articulation Disorder, Phonological Impairment, Dyslexia
- Trial name
- ECRIP (NCT00818428)
- Testing
- Speech Production Intervention, Speech Perception Intervention, Articulation Parent Group
- Where
- 2 sites in Canada
- Volunteers
- 96 people
- Sponsor
- McGill University
Parkinson Disease
REducing SPEECH-related Side-effects of Deep Brain Stimulation in Parkinson's Disease Via Automated Speech Analysis
The investigators' objective is to improve L-dopa sensitive PD-related dysarthria and at the same time reduce DBS-induced speech disorders with the help of automated acoustic analysis in patients with STN-DBS-induced dysarthria.
- Trial name
- RESPEECH-PD (NCT05182892)
- Testing
- Change of stimulation amplitudes in dopaminergic OFF drug state
- Where
- 2 sites in Czechia, Switzerland
- Volunteers
- 45 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Parkinson's Disease, Dysphagia
Efficacy of Voice Treatment for Parkinson's Disease
The purpose of the research study is to determine the effects of two different kinds of speech treatment on certain behaviors in individuals with parkinson's disease.
- Conditions
- Parkinson's Disease, Dysphagia, Dysarthria
- Trial name
- NCT00123084
- Testing
- Voice/Respiration Treatment, Speech/Articulation Treatment
- Where
- 2 sites in United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Anarthria, Dysarthria
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)
The goal of this study is to improve our understanding of speech production, and to translate this into medical devices called intracortical brain-computer interfaces (iBCIs) that will enable people who have lost the ability to…
- Conditions
- Anarthria, Dysarthria, Tetraplegia, Spinal Cord Injuries
- Trial name
- BG-Speech-02 (NCT06094205)
- Testing
- BrainGate Neural Interface System
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Leigh R. Hochberg, MD, PhD.
Cerebral Palsy, Dysarthria
Speech Motor Treatment in Cerebral Palsy
Cerebral palsy (CP) is the most frequent cause of motor disability worldwide, with a prevalence of 2-2.5 per 1000 live births. Children with CP may experience a variety of difficulties with communication including speech.
- Trial name
- NCT04189159
- Testing
- PROMPT
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Fondazione Stella Maris
Speech Sound Disorder
Online Rotating Delivery of Perception/Production Enhanced Treatment for Rhotics
The goal of this clinical trial is to determine whether perceptual training enhances speech perception and production outcomes in children with Residual Speech Sound Disorders (RSSD).
- Trial name
- ORDER (NCT06969521)
- Testing
- Visual acoustic biofeedback: ORDER, Perception Training: ORDER
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Montclair State University
Articulation Disorder, Dysarthria
Evaluating the Efficacy of Opti-Speech for Speech Treatment
The purpose of this study is to determine if feedback from a three-dimensional real-time visualization of the tongue, a program called Opti-Speech, can be used to improve speech.
- Conditions
- Articulation Disorder, Dysarthria, Prelingual Deafness
- Trial name
- NCT02705326
- Testing
- Opti-Speech
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Vulintus, Inc.
Speech Sound Disorder, Language Development Disorders
Exploratory Trial of the "HiDongDong" Language Rehabilitation App for Articulation Delay.
The purpose of this study is to evaluate the effectiveness of the AI-based application "HiDongDong" in improving articulation development in children aged 2 to under 14 years with suspected articulation delays.
- Conditions
- Speech Sound Disorder, Language Development Disorders, Phonological Disorder
- Trial name
- NCT07613268
- Testing
- HiDongDong Intervention, Standard Care / Speech Therapist Intervention
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Seoul National University Bundang Hospital
Primary Progressive Aphasia, Dementia
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates positive effects of speech-language treatment for individuals with PPA…
- Conditions
- Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease
- Trial name
- NCT05741853
- Testing
- Video-Implemented Script Training for Aphasia (VISTA), Lexical Retrieval Training (LRT)
- Where
- 3 sites in United States, Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stephanie Grasso
Speech Therapy, Speech Disorders in Children
High-intensity vs Low-intensity Speech Intervention in Children With Phonological Speech Sound Disorders
Achieving speech that is understandable and acceptable to others is the key outcome in the treatment of phonological speech sound disorders. Therefore, speech therapy provided by a speech-language pathologist is essential.
- Conditions
- Speech Therapy, Speech Disorders in Children, Phonological (Speech) Disorder
- Trial name
- NCT07779759
- Testing
- High-intensity combined phonetic-phonological intervention, Low-intensity combined phonetic-phonological intervention
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Ghent
Nonfluent Aphasia, Progressive, Primary Progressive Nonfluent Aphasia
tDCS and Speech Therapy for Motor Speech Disorders Caused by FTLD Syndromes: a Feasibility Study
The investigators will test the feasibility of using transcranial direct current stimulation (tDCS) and speech therapy to treat participants with motor speech disorders caused by Frontotemporal Lobar Degeneration Pathology…
- Conditions
- Nonfluent Aphasia, Progressive, Primary Progressive Nonfluent Aphasia, Primary Progressive Non Fluent Aphasia, Progressive Supranuclear Palsy
- Trial name
- NCT04883229
- Testing
- Halo Neuroscience Neurostimulator
- Sponsor
- University of California, San Francisco
Speech Sound Disorder
Generalization With AI Navigation Using StaRt
Speech Sound Disorder (SSD) affects a significant portion of school-aged children, leading to social and emotional challenges that can persist into adolescence and adulthood.
- Trial name
- GAINS (NCT06884943)
- Testing
- AI-guided maintenance training with visual-acoustic biofeedback, Treatment as Usual (TAU)
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- New York University
Stroke, Dysarthria
Deep Brain Stimulation + Therapy for Stroke
The purpose of this study is to evaluate the safety and potential benefits of combining deep brain stimulation (DBS) with targeted speech and swallowing rehabilitation in individuals who have experienced a stroke and have…
- Conditions
- Stroke, Dysarthria, Apraxia, Dysphagia
- Trial name
- NCT07849114
- Testing
- Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pirondini, Elvira, PhD
Speech Sound Disorder
Delineation of Sensorimotor Subtypes Underlying Residual Speech Errors
Children with speech sound disorder show diminished accuracy and intelligibility in spoken communication and may thus be perceived as less capable or intelligent than peers, with negative consequences for both socioemotional and…
- Trial name
- C-RESULTS (NCT03736213)
- Testing
- Visual-acoustic biofeedback, Ultrasound biofeedback
- Where
- 3 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- New York University