Clinical trials: Artificial Respiration
COVID-19 Acute Respiratory Distress Syndrome, Respiration, Artificial
Flow-controlled Ventilation (FCV) in Moderate Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19
Flow controlled ventilation (FCV) is a fairly new mode of mechanical ventilation, consisting of a constant inspiratory and expiratory flow. Inspiration is thus comparable to volume controlled ventilation (VCV).
- Trial name
- VICAR (NCT04894214)
- Testing
- Arterial blood gas (ABG), Recording of hemodynamic monitoring, Recording of respiratory monitoring
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- University Hospital, Antwerp
PEEP, Occult
Evaluation of AI Models in Determining the Optimal PEEP
his study is designed as a prospective observational clinical trial. Patients over 18 years old who are hemodynamically stable and require mechanical ventilation in the Intensive Care Unit (ICU) will be included.
- Trial name
- NCT06844916
- Testing
- AI-Assisted PEEP Optimization
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
SARS-CoV Infection, COVID 19
The Efficacy of Different Anti-viral Drugs in COVID 19 Infected Patients
The (World Health Organization) WHO NOR- (Coronavirus infectious disease) COVID 19 study is a multi-centre, adaptive, randomized, open clinical trial to evaluate the safety and efficacy of hydroxychloroquine, remdesivir and…
- Conditions
- SARS-CoV Infection, COVID 19, Acute Respiratory Distress Syndrome ARDS
- Trial name
- NCT04321616
- Testing
- Hydroxychloroquine, Remdesivir, (Standard of Care) SoC
- Where
- Norway
- Volunteers
- 700 people
- Sponsor
- Oslo University Hospital
Dyspnea
Artificial Intelligence to Improve Physicians' Interpretation of Chest X-Rays in Breathless Patients
Identifying the cause of breathlessness in acute patients in the emergency department is critical and challenging. The chest X-ray is central but challenging to read for non-radiologist physicians.
- Trial name
- XRAI (NCT05117320)
- Testing
- AI support
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Respiration, Artificial, Sedated
Influence of Chronic Vascular Diseases on Transcranial Doppler Profiles in Critically Ill Patients
The primary objective of this study is to show that cardiovascular risk factors associated with the chronic elevation of arterial resistance may be associated with "false" profiles of intracranial hypertension during transcranial…
- Trial name
- CritiDop (NCT02898389)
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Body Weight, Post-Op Complication
Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)
This Study aims to develop machine learning models with the ability to predict patients' BMI and complications after Bariatric Surgery (CABS-Score).
- Conditions
- Body Weight, Post-Op Complication, Anastomosis, Leaking, Hiatal Hernia
- Trial name
- NCT05710913
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Dr. Med Anas Taha
Brain Death, Respiration, Artificial
Miniature In-line Respirator
This first-in-human pilot study will test an investigational miniature breathing device called the Hope inVent. The device is a small, single-use, in-line respirator that connects to a breathing tube and uses compressed oxygen to…
- Trial name
- NCT07768215
- Testing
- Hope inVent
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Mechanical Ventilation Complication
Impact of Inspiratory Muscle Pressure Curves on the Ability of Professionals to Identify Patient-ventilator Asynchronies
Patient-ventilator asynchronies can occur as a result of a mismatch between neural (patient) and ventilator inspiratory and expiratory phases.
- Trial name
- Pmus (NCT05144607)
- Testing
- Muscle Pressure curve (Pmus)
- Where
- Brazil
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Bronchopulmonary Dysplasia
Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator
Very premature infants often cannot breathe on their own and require assistance with a respirator. Conventional respirators deliver air or oxygen via a breathing tube placed through the mouth to the airway (endotracheal tube).
- Trial name
- NCT01440647
- Testing
- Extubation to NIPPV, Extubation to CPAP
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Respiration, Artificial, Energy Metabolism
Energy Expenditure in Weaning From Mechanical Ventilation
During weaning from mechanical ventilation process, the energy expenditure in T tube is greater than pressure support ventilation.
- Trial name
- NCT00853060
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Respiration, Artificial, Hemorrhage
Impact of Heparin on the Need for Mechanical Ventilation in Neonates
This study is designed to test an incidental finding of a previous trial in which post hoc analysis showed that the rate of intensive care newborns requiring mechanical ventilation was lower in the group receiving heparin with…
- Trial name
- NCT00196469
- Testing
- heparin
- Where
- Germany
- Volunteers
- 270 people
- Sponsor
- University Medicine Greifswald
Infant, Premature, Diseases, Bronchopulmonary Dysplasia
A Trial of Infant Flow Biphasic Nasal Continuous Airway Pressure (NCPAP) Versus Infant Flow NCPAP for the Facilitation of Extubation in Infants </= 1250 Grams
The purpose of this study is to compare two methods of delivering Nasal Continuous Airway Pressure (NCPAP): Biphasic Mode and a continuous mode, to see which is better in getting babies off the ventilator and decreasing lung…
- Conditions
- Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Apnea of Prematurity
- Trial name
- NCT00308789
- Testing
- Biphasic Infant flow NCPAP, CPAP
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- Mount Sinai Hospital, Canada
Nurses' Knowledge Regarding Initiating Mechanical Ventilation and Nursing Procedures
Nurses' Knowledge of Initiating Mechanical Ventilation in ICUs
To assess intensive care unit (ICU) nurses' knowledge regarding initiation of mechanical ventilation and associated nursing procedures in hospitals of a southern in Iraq.
- Trial name
- ICU-MV-KNOW (NCT07534202)
- Testing
- Assessment of Nurses' Knowledge Regarding Initiating Mechanical Ventilation and Nursing Procedures
- Where
- Iraq
- Volunteers
- 152 people
- Sponsor
- Aqeel Azeez Arrar
Respiration, Artificial, Vascular Filling
Mitral Doppler as a Predictor of Respiratory Worsening After Vascular Filling
Interventional study of the accuracy of a non-invasive testing by echocardiography to predict respiratory worsening after vascular filling.
- Conditions
- Respiration, Artificial, Vascular Filling, Echocardiography
- Trial name
- EVALDM (NCT03447366)
- Testing
- mitral doppler
- Where
- 3 sites in France
- Volunteers
- 87 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Cardiopulmonary Resuscitation
Pilot Study Comparing Ventilation Modes During CPR With Mechanical Compression Device.
Comparison of three ventilation modes (volume controlled, BIPAP and CPAP) during cardiopulmonary re-suscitation with a mechanical compression device in the emergency room.
- Trial name
- COVME (NCT03347175)
- Testing
- Volume controlled ventilation, Pressure controlled ventilation, CPAP mode
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
COPD (Chronic Obstructive Pulmonary Disease), Artificial Intelligence
A Prospective, Multicenter, Portable Pulmonary Function Comparison Study Aimed at Evaluating the External Clinical Validation of the Chronic Obstructive Pulmonary Disease Auxiliary Diagnostic Software LH-002 (Version: 2.0.0) in Clinical Diagnosis Accuracy
Chronic Obstructive Pulmonary Disease (COPD) is widely underdiagnosed in low- and middle-income countries and regions, due to the lack of accessible tools.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Artificial Intelligence, Cough, Diagnosis
- Trial name
- NCT07888712
- Where
- China
- Volunteers
- 466 people
- Sponsor
- Ruijin Hospital
Pediatric Respiratory Diseases, Ventilator Weaning
WOB and Paediatric Mechanical Ventilation
Rationale: The most common approach to weaning infants and children is gradual reduction of ventilatory support ("traditional approach").
- Conditions
- Pediatric Respiratory Diseases, Ventilator Weaning, Respiration, Artificial, Respiratory Failure
- Trial name
- PedWOB (NCT05254691)
- Testing
- Sprinting
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Mechanical Ventilation, Patient-Ventilator Asynchrony
Patient-Ventilator Asynchrony: Occurence and Clinical Impact in Usual Care
The goal of this observational study is to unravel the occurence, impact and relations of Patient-Ventilator Aynchrony (PVA) in mechanically ventilated patients.
- Trial name
- PVA-detection (NCT07624786)
- Testing
- PVA classification software
- Where
- 3 sites in Netherlands
- Volunteers
- 110 people
- Sponsor
- Erasmus Medical Center
ARDS (Acute Respiratory Distress Syndrome)
Influence of Lung Recruitment Potential on Positive End-Expiratory Pressure (PEEP) Titration Strategies in Acute Respiratory Distress Syndrome (ARDS) Patients.
Acute Respiratory Distress Syndrome (ARDS) is characterized by severe hypoxemia and diffuse alveolar collapse, often requiring invasive mechanical ventilation.
- Trial name
- RECRUIT-PEEP (NCT07603310)
- Testing
- Positive End-Expiratory Pressure (PEEP) Titration guided by Static Compliance, Positive End-Expiratory Pressure (PEEP) Titration guided by Transpulmonary Pressure
- Where
- Chile
- Volunteers
- 52 people
- Sponsor
- Hospital Dr. Franco Ravera Zunino
Respiratory Failure
Extubation With or Without Spontaneous Breathing Trial
Spontaneous breathing trial (SBT) has long been thought to be a essential process before extubation. In this study,the investigator hypothesized that SBT could be not essential during weaning from ventilator and investigated…
- Trial name
- SBT (NCT01020773)
- Testing
- spontaneous breathing trial
- Volunteers
- 67 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University