Clinical trials: Ascorbic Acid
Myoma;Uterus, Adenomyosis of Uterus
RCT - Efficacy of Intravenous Vitamin C Versus Placebo on Estimated Blood Loss in Total Abdominal Hysterectomy
Intervention Group: Received two 1 gm doses of Vitamin C intravenously (IV). first Dose: At midnight on the day of surgery. Second Dose: Immediately after the surgical incision.
- Trial name
- Vit C in TAH (NCT07335432)
- Testing
- Vitamin C (Ascorbic Acid)
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Fragile X Syndrome
Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome
The Fragile X syndrome (FXS) was first described by Dr. Martin and Dr. Bell in 1943, in families with several patients affected by sex-linked mental disability.
- Trial name
- SXF-TRA152 (NCT01329770)
- Testing
- Ascorbic Acid (Vitamin C) and Alpha-tocopherol (Vitamin E)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Yolanda de Diego Otero
Birth Asphyxia
First-day High Dose Vitamin C, E in Severe Birth Asphyxia
To study the role of first-day high dose oral vitamin C and first-day single high dose oral vitamin E in hypoxic-ischemic encephalopathy in newborns, in the reduction of morbidity and adverse neurodevelopmental sequelae.
- Trial name
- CEBA (NCT01743742)
- Testing
- Vitamin E, Vitamin C
- Where
- India
- Volunteers
- 95 people
- Sponsor
- Sir Takhtasinhji General Hospital
Liver Transplant Failure and Rejection
Parenteral Ascorbic Acid Repletion in TransplantatIon
A single-center, randomized, double-blinded placebo-controlled trial is proposed to investigate administration of supraphysiologic doses of ascorbic acid (vitamin C, AA) to patients undergoing liver transplantation.
- Trial name
- PARTI (NCT04756063)
- Testing
- Ascorbic acid
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Covid19
Dietary Supplements for COVID-19
This is a double blind, placebo controlled, phase III randomized controlled trial evaluating the effects of the dietary supplements vitamin C, vitamin D, vitamin K, and zinc versus placebo on the overall health, symptom severity…
- Trial name
- NCT04780061
- Testing
- Vitamin D3 50,000 IU, Vitamin C/Zinc, Vitamin K2/D
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Healthy, Suboptimal Vitamin C Levels
The Impact of Qualia Vitamin C+ on Blood Vitamin C Levels
This is a double-blind, placebo-controlled, parallel-group, study evaluating the effect of a Qualia Vitamin C+ formulation on Whole Blood Vitamin C levels in the blood of healthy adults aged 25 years or older.
- Trial name
- NCT07285109
- Testing
- Qualia Vitamin C+
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Qualia Life Sciences
Atrial Fibrillation
Influence of Vitamin C on Post-operative Atrial Fibrillation
Post-operative atrial fibrillation (POAF) is the most common arrhythmia which typically develops 2-3 days after cardiac surgery.
- Trial name
- NCT03592680
- Testing
- Vitamin C
- Where
- Belgium
- Volunteers
- 600 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Catheter-Associated Urinary Tract Infection
Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries
Double-blind placebo-controlled randomized trial aiming to assess the role of Vitamin C supplementation in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.
- Trial name
- NCT05913180
- Testing
- Ascorbic Acid 1000 MG
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- American University of Beirut Medical Center
Iron Deficiency Anaemia Due to Dietary Causes, Folic Acid Deficiency Anemia, Dietary
Prevalence and Impact of Micronutrient (Iron-Folic Acid) Deficiencies on the Health of Adolescent Girls in Coastal Areas of Bangladesh
Anemia and iron-folic acid (IFA) deficiencies are major nutritional concerns among adolescent girls in environmentally vulnerable coastal communities of Bangladesh.
- Conditions
- Iron Deficiency Anaemia Due to Dietary Causes, Folic Acid Deficiency Anemia, Dietary, Anemia
- Trial name
- IFA-AG-Coastal (NCT07903558)
- Testing
- Iron-Folic Acid and Zinc Supplementation, Vitamin C Supplementation
- Where
- Bangladesh
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Patuakhali Science and Technology University
Bowel Disease, Colon Adenoma
Comparison of Low Volume PEG-Asc and Lower Volume PEG-Asc With Bisacodyl
Recently a low-volume polyethylene glycol containing ascorbic acid (PEG-Asc) formulation has proven as safe and effective as traditional 4-L PEG solutions for colonoscopy preparation.
- Trial name
- NCT02980562
- Testing
- Polyethylene Glycols, Bisacodyl
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Anemia, Iron-Deficiency
the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients
IDA patients ofen receive ferrous succinate treatment to speed up the recovery of anemia, the doctor will prescribe ferrous succinate with or without vitamin C according to their own preferences.
- Trial name
- NCT02631668
- Testing
- ferrous succinate and vitamin C, ferrous succinate
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Huashan Hospital
Multiple Myeloma
High Dose Ascorbic Acid for Plasma Cell Disorders
This is a Phase I single-arm open-label clinical study primarily assessing the safety and secondarily, the relative efficacy of low dose melphalan + high dose ascorbate acid (HDAA) in relapsed refractory patients with multiple…
- Trial name
- NCT03602235
- Testing
- Ascorbate, Melphalan
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Christopher Strouse
Hypochlorhydria
Assessment of Gastric pH Changes Induced by Ascorbic Acid Tablets
This study evaluates the use of ascorbic acid, vitamin C, to temporary reduce gastric pH in individuals with omeprazole induced hypochlorhydria.
- Trial name
- NCT04199624
- Testing
- Omeprazole 20mg, Vitamin C
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Indiana University
Metastatic Pancreatic Cancer
Intravenous Vitamin C in Combination With Standard Chemotherapy for Pancreatic Cancer
Eligible candidates will be adults with metastatic pancreatic cancer (confirmed diagnosis with pathology reports and measurable computed tomography (CT) or magnetic resonance imaging (MRI)).
- Trial name
- NCT00954525
- Testing
- Gemcitabine and Erlotinib, Intravenous Vitamin C
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Heart Failure
Vitamin C Supplementation Intervention
This study is to test a low-cost, simple vitamin C supplementation intervention, that is, comparing placebo to 500 mg/day vitamin C and 1 gram/day vitamin C daily to assess feasibility and acceptability of vitamin C…
- Trial name
- NCT04036110
- Testing
- Vitamin C 500 mg, Vitamin C 1000 mg
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of North Carolina, Chapel Hill
Cathartic Colon
Oral Sulfate Solution (SUPREP) Versus Polyethylene Glycol (PEG) Plus Ascorbic Acid
The aims of the present study is to compare oral sulfate solution (OSS) with low-dose polyethylene glycol plus ascorbic acid (2-L PEG/Asc) for bowel cleansing efficacy.
- Trial name
- NCT02761213
- Testing
- Oral sulfate solution (OSS), 2-L PEG/Asc
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bo-In Lee
Pancreatic Neoplasms
Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I
This is a phase 1 (first in man) study testing the safety of adding high dose ascorbate (vitamin C) to standard radiation and chemotherapy for treatment of pancreatic cancer.
- Trial name
- NCT01852890
- Testing
- Ascorbate, Gemcitabine, Radiation therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Joseph J. Cullen
Colorectal Cancer
Effect of Simethicone on Bowel Preparation for Colonoscopy
Optimal bowel preparation is essential for colonoscopy efficacy and safety. Mucosal visualization during colonoscopy is often limited by residual stool, bubbles, bile, intraluminal fluid, and debris, which increase the risk of…
- Trial name
- NCT02548403
- Testing
- PEG-Asc, PEG-Asc with simethicone
- Where
- South Korea
- Volunteers
- 260 people
- Sponsor
- Korea University Anam Hospital
Skin Cancer
The Effect of Green Tea and Vitamin C on Skin Health
There is little information on the effect of oral bioactive compounds on human skin clinically despite evidence of a beneficial effect from laboratory studies.
- Trial name
- NCT01032031
- Testing
- Green tea + vitamin C high dose
- Where
- United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Manchester
End Stage Renal Disease
Evaluation of The Effect of Rutin and Vitamin C on the Oxidative Stress in Hemodialysis Patients
The aim of the study is to evaluate the effect of rutin and vitamin C on selected oxidative stress and inflammatory markrers. Patients will be recruited according to the inclusion and exclusion criteria and will be divided into 3…
- Trial name
- NCT04955145
- Testing
- RUTA C 60
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Ain Shams University