Clinical trials: Ascorbic Acid
Deficiency, Vitamin C, Chronic Disease
A Long-term Observational Study to Describe the Use of Vitamin-C Injektopas® 7.5 g in Patients With Vitamin C Deficiency
The goal of this observational study is to learn more about the disease and the symptoms where the product will use and in which patient groups. Further on, it is interesting to know clinical pictures, the symptoms improve.
- Conditions
- Deficiency, Vitamin C, Chronic Disease, Acute Disease
- Trial name
- NCT06983847
- Where
- Austria
- Volunteers
- 1,000 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Osteoporosis, Vitamin C Deficiency
Link Between ASCorbemia Level and Osteoporosis
This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis.
- Conditions
- Osteoporosis, Vitamin C Deficiency, Vertebral Fractures
- Trial name
- ASCO (NCT07660484)
- Testing
- Plasma vitamin C assessment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Ascorbic Acid, Postoperative Pain
The Impact of Intravenous Vitamin C Combined With Nerve Blocks on Postoperative Pain and Recovery After Total Knee Arthroplasty
The aim of this prospective randomized-control study was to evaluate the impact of a single high-dose intravenous vitamin C added to ultrasound-guided blocks at induction on postoperative pain, sngception and early functional…
- Trial name
- NCT05514197
- Testing
- Ascorbic acid 100mg/kg, Maximus 10g, Control Rx
- Where
- Taiwan
- Volunteers
- 73 people
- Sponsor
- Chimei Medical Center
Vitamin C Deficiency, Scurvy
Study of Prevalence and Risk Factors of Hypovitaminosis C in Long Term Care Unit
The clinical finding of skin rashes which appear after a vitamin C deficiency in Long Term Care Unit leads us to believe that the institutional diet could predispose to this kind of deficiency.
- Trial name
- Vitamin C (NCT03807791)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Deficiency, Vitamin C
Hypovitaminosis C Prevalence and Risk Factors in an Acute Geriatric Unit
Vitamin C is essential for numerous biological processes as it acts as a cofactor in various hydroxylation reactions, but also as a powerful antioxidant.
- Trial name
- HYPO-VIT-C (NCT05668663)
- Testing
- Plasmatic Vitamin C concentrations (known as ascorbemia) on a single blood sample
- Where
- France
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Transplantation, Ascorbic Acid Deficiency
Observational Study on the Variation of Ascorbic Acid in Patients Undergoing Solid Organ Transplantation
The objective of this observational clinical study is to evaluate the variations in ascorbic acid during the transplantation phases and how these variations influence the oxidative status and patient outcome.
- Trial name
- REDOX-TX (NCT06395259)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Policlinico Hospital
Hyperemesis Gravidarum, Nausea Gravidarum
Chewing Gum Containing Vitamin-c to Treat Emesis Gravidarum
Nausea and vomiting is a common complication of pregnancy and occurs in 70-80% of all pregnancies. The symptoms usually start 2-4 weeks after fertilization and peak between the 9th and 16th week of gestation.
- Conditions
- Hyperemesis Gravidarum, Nausea Gravidarum, Vitamin C Deficiency
- Trial name
- NCT04284696
- Testing
- Pregnan-C-Gum(R) chewing gum
- Where
- Austria
- Volunteers
- 126 people
- Sponsor
- Medical University of Vienna
Ascorbic Acid, Neurosurgical Procedures
Effect of Vitamin C on Postoperative Pulmonary Complications After Intracranial Tumor Surgery
The goal of this clinical trial is to investigate the effect of perioperative administration of vitamin C on postoperative pulmonary complications, with the aim of providing a safe and effective medication regimen for the…
- Conditions
- Ascorbic Acid, Neurosurgical Procedures, Humans, Ventilator-Induced Lung Injury
- Trial name
- NCT06421688
- Testing
- Ascorbic acid, Saline
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Qianfoshan Hospital
Hypothyroidism, Primary Hypothyroidism
Effect of Vitamin C Supplementation in Patients With Primary Hypothyroidism
Thyroid disease affects almost a quarter of a billion individuals worldwide and more than 50% of them being not aware of this condition.
- Conditions
- Hypothyroidism, Primary Hypothyroidism, Vitamin C Deficiency
- Trial name
- NCT05733078
- Testing
- Vitamin C, Oral Rehydration Salt Formulations
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Dr Adnan Agha
Adverse Effects, Ascorbic Acid
Systemic Adverse Effects After Osteopathic Treatment and Vitamin C
The goal of this triple-blind randomized clinical trial is to learn about systemic adverse effects in first visit patients who attend an osteopathic medicine center in Barcelona.
- Conditions
- Adverse Effects, Ascorbic Acid, Oxidative Stress
- Trial name
- NCT06102577
- Testing
- 1gr. Vitamine C, control group
- Where
- Spain
- Volunteers
- 99 people
- Sponsor
- Centre Medicina Esportiva i Osteopatia, Spain
Catheter-Associated Urinary Tract Infection, Ascorbic Acid
Vitamin C for the Prevention of UTI in Women Who Undergo Elective Gynecological Surgeries
This open-label randomized trial aims at assessing the role of Vitamin C pills in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.
- Trial name
- NCT04261036
- Testing
- Ascorbic Acid 1000 mg
- Where
- Lebanon
- Sponsor
- American University of Beirut Medical Center
Liver Transplantation, Postreperfusion Syndrome
Ascorbic Acid to Prevent Postreperfusion Syndrome in Liver Transplantation
The goal of this clinical trial is to test the efficacy of intravenous ascorbic acid in preventing the postreperfusion syndrome in liver transplantation.
- Conditions
- Liver Transplantation, Postreperfusion Syndrome, Ascorbic Acid
- Trial name
- VITACTOH (NCT05754242)
- Testing
- Ascorbic acid, 0.9% Saline solution
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Burns, Ascorbic Acid Deficiency
Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C
Burn injury is marked by a large release of inflammatory mediators which disrupt the normal capillary barrier and cause a rapid shift of intravascular fluid into interstitial spaces, ultimately leading to shock and death.
- Conditions
- Burns, Ascorbic Acid Deficiency, Burn Shock, Burn Degree Second
- Trial name
- NCT05612867
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Arrowhead Regional Medical Center
Vitamin C Deficiency, Acute Disease
A Long-term Study to Describe the Use of PASCORBIN® 7.5 g in Patients With Vitamin C Deficiency
The aim of this long-term observational study is the documentation of the use of PASCORBIN® 7.5 g in patients with vitamin C deficiency.
- Conditions
- Vitamin C Deficiency, Acute Disease, Chronic Disease
- Trial name
- NCT02422901
- Testing
- vitamin C
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Vitamin C Deficiency
The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis
The effect of vitamin C supplementation on GCF total oxidant capacity in smoker patients with periodontitis following non-surgical periodontal therapy.
- Trial name
- NCT05009355
- Testing
- Vitamin C
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitamin C Deficiency, Smoking
The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients
The goal of this study is to perform a randomized clinical trial to assess the effects of vitamin C versus placebo on wound healing in mandibular fracture patients.
- Conditions
- Vitamin C Deficiency, Smoking, Surgery, Surgery--Complications
- Trial name
- NCT03938584
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Hennepin Healthcare Research Institute
Septic Shock, Ascorbic Acid Deficiency
Outcomes of Septic Shock Patients Treated With a Metabolic Resuscitation Bundle Consisting of Intravenous Hydrocortisone, Ascorbic Acid and Thiamine.
This is a retrospective chart review that will measure the impact on outcomes in septic shock patients who were resuscitated with a novel combination of medicines called iHAT (intravenous hydrocortisone -ascorbic acid-thiamine).
- Trial name
- NCT03913468
- Testing
- Intravenous Ascorbic Acid
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- University of Wisconsin, Madison
Vitamin C Deficiency
The Effect of Liposome Vitamin C on the Absorption and Metabolism of the Human Body.
To evaluate the difference between vitamin C in the form of oral liposomes and general vitamin C in a fixed period of time in plasma and urine.
- Trial name
- NCT04886752
- Testing
- vitamin C without liposome, liposomal process A vitamin C, liposomal process B vitamin C (Double Nutri™)
- Where
- Taiwan
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Contrast-induced Nephropathy, Statin
Effects Of Combination Therapy Of Statin And Ascorbic Acid For Prevention Of Contrast-Induced Nephropathy
To evaluate the benefit for statin use in prevention of of CI-AKI after computed tomography urogram (CTU).
- Conditions
- Contrast-induced Nephropathy, Statin, Ascorbic Acid, AKI
- Trial name
- NCT03391830
- Testing
- Atorvastatin-Ascorbic acid
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Mansoura University
Bowel Preparation, Sodium Picosulfate and Magnesium Citrate
Combination Method Using Sodium Picosulfate and Magnesium Citrate and PEG With Ascorbic Acid for Bowel Preparation
The aim of this study is to compare the efficacy depending on the order of the sequential combination method using sodium picosulfate and magnesium citrate (PMC) and PEG with ascorbic acid for bowel preparation.
- Conditions
- Bowel Preparation, Sodium Picosulfate and Magnesium Citrate, Polyethylene Glycol With Ascorbic Acid
- Trial name
- NCT02979223
- Testing
- sodium picosulfate and magnesium citrate, polyethylene glycol with ascorbic acid
- Where
- South Korea
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea