Clinical trials: Ascorbic Acid
Cardiovascular Risk Factor
Vitamin C to Reduce Morning Cardiovascular Risk
This study will test the efficacy of Vitamin C to counteract morning cardiovascular (CV) risk markers in a randomized, double blind, placebo controlled crossover pilot study.
- Trial name
- NCT03290612
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Angina Pectoris
Treatment of Reperfusion Event by Vitamin C Infusion
Primary Hypothesis: Prophylactic Vitamin C Intravenous Infusion at the time of percutaneous coronary intervention (PCI) would limit the size of the infarct, assessed by measurements of cardiac biomarkers, during acute myocardial…
- Trial name
- TREVI (NCT01090895)
- Testing
- Vitamin C
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Roma La Sapienza
OCD
Effect of Vitamin C Upon SSRI-treated OCD Patients
Title: Effect of Vitamin C upon Selective Serotonin Reuptake Inhibitors (SSRIs) - treated Obsessive Compulsive Disorder (OCD) patients.
- Trial name
- NCT03754647
- Testing
- Vitamin C
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Crohn Disease
Effect of Ileocolonic Delivered Vitamins and an Anti-Inflammatory Diet on Crohn's Disease and Healthy Volunteers
This study will evaluate if the Groningen Anti-Inflammatory Diet and the ileocolonic delivery of vitamin B2, B3 and C can positively influence the course of Crohn's disease and can positively alter the gut microbiome of Crohn's…
- Trial name
- Vita-GrAID (NCT04913467)
- Testing
- Groningen Anti-Inflammatory Diet (GrAID), ColoVit capsule
- Where
- Netherlands
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Hyperlactatemia, Cardiac Disease
Influence of High Vitamin C Dose on Lactate During and After Extracorporeal Circulation
The aim of our study is to find out whether high doses of vitamin C before cardiopulmonary bypass and during the first 24 hours after that have and impact of lowering the incidence of hyperlactatemia.
- Conditions
- Hyperlactatemia, Cardiac Disease, Bypass Complication, Valve Disease, Heart
- Trial name
- NCT04046861
- Testing
- ascorbic acid,
- Where
- Slovenia
- Volunteers
- 70 people
- Sponsor
- University Medical Centre Maribor
Pollution; Exposure
Effect of an Oral Acerola Juice Powder on Skin Beauty Parameters in Women Exposed to Environmental Stresses
The study is being conducted to evaluate the efficacy and the safety of an oral acerola-based product on skin ageing parameters.
- Trial name
- NCT07229131
- Testing
- Acerola Juice Powder 1200 mg/day, Acerola Juice Powder 600 mg/day
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Diana SAS
Covid19
RCT,Double Blind, Placebo to Evaluate the Effect of Zinc and Ascorbic Acid Supplementation in COVID-19 Positive Hospitalized Patients in BSMMU
The first COVID-19 case was identified on March 7, 2020. Since then, 4127 deaths of the total 3,40583 confirmed cases are reported in Bangladesh of August 26, 2020.
- Trial name
- NCT04558424
- Testing
- zinc gluconate and ascorbic acid
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Autism Spectrum Disorder
Effect of Increasing Total Antioxidant Capacity in Autism Spectrum Disorder
This double-blind, randomized, controlled trial (RCT) has the aim to evaluating the effectiveness of increasing Total Antioxidant Capacity (TAC) as add-on intervention in two cohorts of patients with Autism Spectrum Disorder…
- Trial name
- TACASD (NCT06623227)
- Testing
- Vitamin E and C
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Rinvil Renaldi
Maxillofacial Abnormalities, Maxillofacial Injuries
Vitamin C Level Effect in Orthognathic Surgery
Comparing the pre and post-operative blood plasma levels of vitamin C according to oxidative stress and investigate the correlation between post-operative analgesia requirement and vitamin C levels following orthognathic surgery.
- Conditions
- Maxillofacial Abnormalities, Maxillofacial Injuries, Maxillofacial Trauma
- Trial name
- NCT04416386
- Testing
- Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Progression of Atherosclerotic Plaque, Coronary Artery Disease
Coronary Chronic Total Occlusion and Oxidative Balance
The presence of chronic blockage of coronary arteries, which we may accept as the terminal point of atherosclerotic coronary artery disease, is closely associated with a poor prognosis.
- Trial name
- NCT04754880
- Testing
- Comparison of oxidative and antioxidative markers between groups
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Breast Cancer
Effect of Vitamin C and E in Breast Cancer Patients Undergoing Chemotherapy
Title: Effect of Vitamin C and Vitamin E in Breast Cancer patients undergoing Chemotherapy. Purpose of the study: The present study has been designed to assess the effects of vitamin C and vitamin E superimposed upon…
- Trial name
- NCT04463459
- Testing
- Vitamin C, Vitamin E
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Septic Shock
Steroids, Thiamine and Ascorbic Acid in Septic Shock
The objective of this project is to determine if in patients admitted to the hospital with septic shock (population), does treatment with a bundle including hydrocortisone, thiamine, and ascorbic acid improve in-hospital or…
- Trial name
- STASIS (NCT04134403)
- Testing
- STASIS
- Volunteers
- 80 people
- Sponsor
- Baqiyatallah Medical Sciences University
Vitamin C Deficiency
The Effect of Vitamin C on Quality of Life of Terminal Cancer Patients
This study determines whether high dose vitamin C is effective for quality of life in terminal cancer patients.
- Trial name
- NCT03224572
- Testing
- high-dose vitamin C 30gm, normal saline
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Delayed Onset Muscle Soreness, DOMS
COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)
The study is designed as a proof of concept, single-center, randomized, double-blind, placebo controlled study to assess the safety and efficacy of Comboprofen (Ibuprofen + Magnesium + Vitamin C) compared to placebo, Ibuprofen…
- Trial name
- NCT03223519
- Testing
- Comboprofen, Ibuprofen, Magnesium
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Spherium Biomed
Plasma Cell Disorder
High Dose Ascorbic Acid (HDAA) in Patients With Plasma Cell Disorders
The purpose of this research is to evaluate whether HDAA in combination with a single dose of 100 mg/m2 IV melphalan followed by autologous stem cell transplantation (ASCT) is safe and effective for subjects with relapsed…
- Trial name
- NCT06313502
- Testing
- 75gm HDAA, 100gm HDAA, 125gm HDAA
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Arkansas
Nutritional Rickets, Bone Turnover Rate Disorder
Effectiveness of Vitamin C Supplementation in Treatment of Rickets
Effectiveness of therapeutic dose of vitamin C in infants and children with nutritional rickets as an adjuvant therapy with vitamin D and calcium The study is two armed Randomized Control Trial, to validate the role of Vit C…
- Trial name
- NCT05310760
- Testing
- Vit C
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
PreDiabetes, Nutrition
Zinc, Chromium, Vitamin C, and Copper Combination Supplement for Prediabetes Progression
Currently, the incidence of diabetes mellitus is increasing worldwide. People with prediabetes have higher risk to develop diabetes mellitus type 2.
- Trial name
- CHANGE (NCT04511468)
- Testing
- Zinc, Chromium, Vitamin C, and Copper Supplementation, Standard healthy lifestyle intervention
- Where
- Indonesia
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Higher Uric Acid Concentrations (>5,5 mg/dl), Healthy
Influence of Hesperidin and Vitamin C on Uric Acid Concentration
Aim of the study is to investigate the impact of hesperidin and/or vitamin C on elevated uric acid concentrations.
- Trial name
- HesperiDrinC (NCT04316390)
- Testing
- Control, Hesperidin, Vitamin C
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Iron Deficiency
Effect of Vitamin C on Iron Absorption
Iron deficiency is a common health problem worldwide. Ferrous fumarate (a form of iron) is often added to foods in an effort to prevent iron deficiency.
- Trial name
- NCT00570895
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Contrast-induced Nephropathy, Statin
Effects Of Combination Therapy Of Statin And Ascorbic Acid For Prevention Of Contrast-Induced Nephropathy
To evaluate the benefit for statin use in prevention of of CI-AKI after computed tomography urogram (CTU).
- Conditions
- Contrast-induced Nephropathy, Statin, Ascorbic Acid, AKI
- Trial name
- NCT03391830
- Testing
- Atorvastatin-Ascorbic acid
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Mansoura University