Clinical trials: Ascorbic Acid
Vitamin C, Pneumonia, Viral
Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia
2019 new coronavirus (2019-nCoV) infected pneumonia, namely severe acute respiratory infection (SARI) has caused global concern and emergency.
- Conditions
- Vitamin C, Pneumonia, Viral, Pneumonia, Ventilator-Associated
- Trial name
- NCT04264533
- Testing
- VC, Sterile Water for Injection
- Where
- China
- Volunteers
- 56 people
- Sponsor
- ZhiYong Peng
Hypovitaminosis, Vitamin C Abnormal
Vitamin C 4 Care Homes
Older people in care homes are one of the most vulnerable groups with respect to risk, morbidity and mortality of severe coronavirus disease-2019 (COVID-19).
- Trial name
- VITA-C4CARE (NCT05122481)
- Testing
- Vitamin C
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Aberdeen
Periodontitis
Evaluation of iPRF With Vitamin C in StageII Grade A Periodontitis
Comparing the effect of using vitamin C with injectable PRF as a locally delivered adjunct to scaling and root planing versus scaling and root planing with local delivery of injectable PRF and scaling and root planing alone on…
- Trial name
- NCT05129267
- Testing
- Group B, Group C
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Rhinitis, Allergic, Allergy
Effect of Vitamin C on Allergy Skin Test
This study will assess the effect of taking vitamin C on allergy skin test.
- Trial name
- NCT05810233
- Testing
- Ascorbic acid 1000mg
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- National University of Malaysia
Patient Blood Management, Cardiac Surgery
Effect of the Combined Programme on Perioperative Anaemia（CPPA）
We used the preoperative intervention of iron sucrose in combination with human erythropoietin and vitamin C as an innovative combination therapy.
- Conditions
- Patient Blood Management, Cardiac Surgery, Iron Deficiency Anemia
- Trial name
- NCT05353348
- Testing
- Iron Sucrose, recombinant human erythropoietin, ascorbic acid, conventional treatment
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
HIV-1-infection, AIDS
Protect and Improve Cluster of Differentiation 4 (CD4) Cells and B Cells Lymphocytes
This is a plant-based medication used to increase the amount, protect, and reduce HIV's impact on T and B lymphocytes.
- Trial name
- NCT04770701
- Testing
- Ahah Drug
- Where
- Vietnam
- Sponsor
- Trieu, Nguyen Thi, M.D.
Infections, Respiratory Tract
An Efficacy and Safety Study of Theraflu Day Powder as Oral Solution for Cold and Flu
The purpose of the study is to assess the short term efficacy of the Theraflu Aktiv powder for oral solution in the Russian population as compared to an untreated group to support the indication of "Short term relief of the…
- Trial name
- NCT02678234
- Testing
- Paracetamol, phenylephrine HCl, and vitamin C
- Sponsor
- GlaxoSmithKline
Postoperative Pain
Preoperative Melatonin or Vitamin C Administration on Postoperative Analgesia
The investigators designed a randomized double-blind placebo-controlled trial to evaluate the effect of preoperative single dose of oral melatonin and vitamin C administration on postoperative analgesia in patients undergoing…
- Trial name
- NCT02639741
- Testing
- Melatonin, Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Cukurova University
Chronic Cholecystitis, Cholelithiasis
Effect of Vitamin C on Postoperative Pain After Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effect of Vitamine C supplements to be helpful to reduce the postoperative pain after laparoscopic cholecystectomy through the double-blinded randomized controlled trial.
- Trial name
- NCT02553551
- Testing
- Vitamin C
- Where
- South Korea
- Volunteers
- 320 people
- Sponsor
- Taeho Hong
Gingival Pigmentation
Vitamin C Mesotherapy Versus Diode Laser for the Management of Physiologic Gingival Pigmentation
Physiologic pigmentation affects the gingival esthetics. Laser ablation has been recently used as the most effective and reliable technique for gingival depigmentation.
- Trial name
- NCT05608057
- Testing
- Vitamin C mesotherapy, Diode laser
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Hams Hamed Abdelrahman
Bowel Preparation Solution
PEG-Asc Vs. SPMC for Bowel Preparation in Capsule-based Procedures
This clinical research study is designed to find out which of two different types of bowel preparation works best for people undergoing capsule-based endoscopy procedures.
- Trial name
- NCT07206329
- Testing
- Polyethylene Glycol plus Ascorbic Acid (PEG-Asc), Sodium Picosulfate with Magnesium Citrate (SPMC)
- Where
- Portugal
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Vitamin C Deficiency
The Effect of Liposome Vitamin C on the Absorption and Metabolism of the Human Body.
To evaluate the difference between vitamin C in the form of oral liposomes and general vitamin C in a fixed period of time in plasma and urine.
- Trial name
- NCT04886752
- Testing
- vitamin C without liposome, liposomal process A vitamin C, liposomal process B vitamin C (Double Nutri™)
- Where
- Taiwan
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Premature Rupture of Membranes, Fetal Complications
Cranberry, Hibiscus, and Vitamin C Extracts Versus Placebo in Latency of Premature Rupture of Membranes.
The main objective of this clinical trial is to evaluate the effect of cranberry, hibiscus and vitamin C extracts supplementation on the duration of the latency of premature rupture of membranes in pregnant women between 24 and…
- Trial name
- SBERRY (NCT06788132)
- Testing
- Cranberry products
- Where
- Honduras
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ricardo A Gutierrez Ramirez, MD, MSc, FACOG
Diminished Ovarian Reserve, IVF Outcomes
The Effect of VitC on IVF Outcome of DOR Patients
In the context of the accelerating aging population and the continuous decline in birth rates nationwide, delaying reproductive aging in women and protecting the fertility of women of childbearing age have become urgent issues…
- Trial name
- DORIVF-VC (NCT06794047)
- Testing
- Vitamin C
- Where
- 6 sites in China
- Volunteers
- 1,100 people
- Sponsor
- Peking University Third Hospital
Sepsis
High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda
This feasibility study serves to determine if it is possible to perform a powered randomized control trial of high-dose intravenous vitamin C (ascorbic acid) as an adjunctive medication in the management of sepsis and septic…
- Trial name
- NCT04088591
- Testing
- Ascorbic Acid 500Mg/Ml Inj, Dextrose in Water
- Where
- Rwanda
- Sponsor
- Virginia Commonwealth University
Glioblastoma, GBM
A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme
This is a phase 1 (first in man) study testing the safety of adding high dose ascorbate (vitamin C) to standard radiation and chemotherapy for initial treatment of glioblastoma multiforme (GBM).
- Conditions
- Glioblastoma, GBM, Glioblastoma Multiforme
- Trial name
- NCT01752491
- Testing
- Ascorbate, Temozolomide, Radiation therapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Joseph J. Cullen, MD, FACS
Healthy, Pharmacokinetic
A Pharmacokinetic Study of Single Oral Doses of Six Different Vitamin C Product Forms
Vitamin C (ascorbic acid) is an essential nutrient linked to many aspects of basic human physiology. It is a potent antioxidant and involved as a cofactor for many human enzymes, and its extreme deficiency can lead to a fatal…
- Trial name
- NCT06471023
- Testing
- TP1, TP2, TP3
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Vitamin D Deficiency
The Effect of Combinatorial Nutritional Supplementation on Immune Function in Healthy Older Adults
Many older adults do not get enough zinc, vitamin C and vitamin D, and this can be related to decreased ability to fight infection.
- Trial name
- NCT02876315
- Testing
- Redoxon VI
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Carcinoma, Non-Small-Cell Lung, Stage IIIA Non-small Cell Lung Cancer
Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancer
This trial studies efficacy and safety of combination of vitamin C infusion with modulated electro-hyperthermia (mEHT) in treatment of non small cell lung cancer patients.Phase I of this clinical study is to find the tolerable…
- Conditions
- Carcinoma, Non-Small-Cell Lung, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
- Trial name
- VCONSCLC (NCT02655913)
- Testing
- vitamin C, Modulated Electro-Hyperthermia (mEHT), Supportive care
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Clifford Hospital, Guangzhou, China
Septic Shock
Blessing or Curse? Combined Vitamin Therapy in Non Viral Septic Shock.
Introduction: Septic shock leads to high morbidity and mortality in critically ill patients. Several lower-case scientific studies have supported the synergistic positive effect of vitamin C, thiamine, and hydrocortisone on…
- Trial name
- NCT06152458
- Testing
- Vitamin C
- Where
- Hungary
- Volunteers
- 43 people
- Sponsor
- University of Pecs