Clinical trials: Ascorbic Acid
Type 2 Diabetes Mellitus
Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus
Null hypothesis: No significant effect of vitamin C 500 mg Supplementation on the severity of micro-vascular complications of type 2 Diabetes Mellitus (DM).
- Trial name
- Vit C (NCT01319734)
- Testing
- Vitamin C, glyburide
- Where
- Sudan
- Volunteers
- 50 people
- Sponsor
- Al-Neelain University
Acute Lung Injury, Transfusion Related
Role of Ascorbic Acid Infusion in Critically Ill Patients With Transfusion Related Acute Lung Injury
TRALI was defined as "acute noncardiogenic pulmonary edema typically occurs ≤ 6 hours following transfusion of plasma-containing blood products, such as packed red blood cells, fresh frozen plasma, platelets, or cryoprecipitate."…
- Trial name
- ASTRALI (NCT04153487)
- Testing
- Ascorbic Acid Injectable Product
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Damanhour University
Bowel Preparation, Sodium Picosulfate and Magnesium Citrate
Combination Method Using Sodium Picosulfate and Magnesium Citrate and PEG With Ascorbic Acid for Bowel Preparation
The aim of this study is to compare the efficacy depending on the order of the sequential combination method using sodium picosulfate and magnesium citrate (PMC) and PEG with ascorbic acid for bowel preparation.
- Conditions
- Bowel Preparation, Sodium Picosulfate and Magnesium Citrate, Polyethylene Glycol With Ascorbic Acid
- Trial name
- NCT02979223
- Testing
- sodium picosulfate and magnesium citrate, polyethylene glycol with ascorbic acid
- Where
- South Korea
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Pain Perception, Root Resorption
The Potential Effect of the Local Administration of Vitamins C and E on Orthodontic Treatment: A Randomized Clinical Trial
Brief Summary of the Study This study investigates the effects of locally administered vitamins C and E on orthodontic tooth movement during the initial stage of treatment.
- Conditions
- Pain Perception, Root Resorption, Rate of Orthodontic Tooth Movement, Biomarkers
- Trial name
- NCT06847880
- Testing
- 1: Vitamin C Supplementation, Vitamin E Supplementation, Saline Solution (Control)
- Where
- 3 sites in Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Charcot-Marie-Tooth Disease, Type Ia
High Dose Ascorbic Acid Treatment of CMT1A
This study will look at the impact of ascorbic acid (Vitamin C) on the progression of disease in people with CMT1A as compared to volunteers receiving a placebo.
- Trial name
- NCT00484510
- Testing
- Ascorbic acid (Vitamin C)
- Where
- 3 sites in United States
- Volunteers
- 110 people
- Sponsor
- Wayne State University
Pain, Acute
Impact of Vitamin C on opioïd Consumption After an Emergency Department Visit for Acute Musculoskeletal Pain
Recent evidence has shown that vitamin C has some analgesic properties and can therefore reduce opioids used during healing. Vitamin C analgesic effect has been explored mostly during the short-term postoperative context or in…
- Trial name
- NCT05555576
- Testing
- Vitamin C
- Where
- Canada
- Volunteers
- 464 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Ulcerative Colitis
Comparison of 4L Polyethylene Glycol and 2L Polyethylene Glycol With Ascorbic Acid in Inactive UC Patients
The purpose of this study is to compare preference of the patients, efficacy of preparation, and safety between 4 L polyethylene glycol and 2 L of polyethylene glycol with ascorbic acid in patients with inactive ulcerative…
- Trial name
- 2SCANI (NCT01929668)
- Testing
- polyethylene glycol, Ascorbic Acid
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Kyungpook National University Hospital
Cancer Pain, Quality of Life
Meditation With Virtual Reality for Cancer Pain Relief in the Pain Therapy and Palliative Care Service
Cancer is a disabling, challenging and growing global disease. Although early diagnosis and adequate treatment of oncological disease have been developing rapidly, a large part of the population remains without access to…
- Conditions
- Cancer Pain, Quality of Life, Palliative Medicine
- Trial name
- NCT06328751
- Testing
- Case group, Active control group, Passive control group
- Where
- Brazil
- Volunteers
- 129 people
- Sponsor
- Emily Santos Montarroyos
Rotator Cuff Tear
Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair
1. Treatment of rotator cuff tear The rotator cuff tear is the most demanding part of the shoulder surgery. Rotator cuff degeneration is thought to be the largest cause of rotator cuff tear.
- Trial name
- VITCRCR (NCT02992028)
- Testing
- Intravenous Nutrition (Vitamins) injection, Intravenous Saline injection
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Himchan Hospital
Respiratory Tract Infection Viral
Echinacea Junior vs Vitamin C in Children 4-12 Years Old
Aim of this study is to investigate efficacy and safety of Echinaforce Junior Tablets (250mg) in comparison with Vitamin C tablets in the prevention of acute viral respiratory tract infections.
- Trial name
- NCT02971384
- Testing
- Echinaforce
- Where
- Switzerland
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
Inflammation, Fibrosis
Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)
No proven treatment exists for nonalcoholic fatty liver disease (NAFLD) in children and adolescents. We aim to determine the efficacy of lifestyle intervention with or without antioxidant therapy in pediatric NAFLD.
- Conditions
- Inflammation, Fibrosis, Insulin Resistance
- Trial name
- VITENAFLD (NCT00655018)
- Testing
- Vitamin treatment (alpha tocopherol plus ascorbic acid)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Colorectal Cancer, Pancreatic Cancer
High Dose Vitamin C Intravenous Infusion in Patients With Resectable or Metastatic Solid Tumor Malignancies
This is a multicenter, single arm, 3-cohort, open-label trial of high dose Vitamin C intravenous infusion in subjects with solid tumor malignancies who are eligible for resection (cohort A) or with extended RAS (e.g.KRAS or NRAS)…
- Conditions
- Colorectal Cancer, Pancreatic Cancer, Lung Cancer
- Trial name
- NCT03146962
- Testing
- Vitamin C
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- Weill Medical College of Cornell University
Diabetes
Vitamins C and Vitamin E and Cardiovascular Risk
The proposed study will examine the hypothesis that vitamin C and vitamin E given to type 2 diabetic individuals will provide effective anti-inflammatory, anti-thrombotic, and anti-oxidative atherosclerotic protection when…
- Trial name
- NCT00362518
- Testing
- Study Arm A, Study Arm B, Study Arm C
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Lumbar Spine Surgery
Vitamin C Supplement for Lumbar Spine Surgery
By doing this study, researchers hope to learn effects of Vit C on lumbar spine surgery outcomes.
- Trial name
- NCT03918694
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Kansas Medical Center
Atrial Fibrillation, Atrial Flutter
Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery
Atrial Fibrillation (AF) is a common postoperative complication of cardiac surgery, occuring in approximately 25-30% of coronary artery bypass graft (CABG) patients and 35-40% of heart valve repair/replacement patients.
- Trial name
- NCT00953212
- Testing
- beta blockers, amiodarone, ascorbic acid
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- MaineHealth
Nutritional Anemia
A Study to Compare Liposomal Iron With Ferrous Ascorbate in the Treatment of Iron Deficiency Anemia in Children
This trial is designed to compare the efficacy of ferrous ascorbate versus liposomal iron for the treatment of nutritional iron deficiency anemia (IDA) amongst 6 to 59 months age children as determined by the increase in…
- Trial name
- NCT05957328
- Testing
- Ferric Pyrophosphate Liposomal, ferrous ascorbate
- Where
- India
- Volunteers
- 96 people
- Sponsor
- All India Institute of Medical Sciences
The Impact of Vitamin c and Epicatechin Upon Antioxidant Capactity
Cross-over Double-blind Intervention to Investigate the Effects of Defined Antioxidant-containing Drinks on Time Course of Antioxidant Capacity
The aim of this project is to measure the differences in antioxidant capacity at different time points after consuming a single dose of antioxidant-containing drink (vitamin C or epicatechin) compared with a control drink in 10…
- Trial name
- NCT02898571
- Testing
- Vitamin C, epicatechin
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Periodontal Bone Loss
Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects
This study is meant to assess clinically the possible predictable clinical attachment gain regarding the use of vitamin C with platelet rich fibrin versus platelet rich fibrin alone in the treatment of periodontal intrabony…
- Trial name
- NCT03707483
- Testing
- combination of vitamin C and platelet rich fibrin
- Volunteers
- 20 people
- Sponsor
- Cairo University
COVID, Corona Virus Infection
Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation
The purpose of this study is to examine the impact of ascorbic acid (vitamin c) and zinc gluconate in reducing duration of symptoms in patients diagnosed with coronavirus disease 2019 (COVID-19).
- Trial name
- COVIDAtoZ (NCT04342728)
- Testing
- Ascorbic Acid, Zinc Gluconate, Ascorbic Acid and Zinc Gluconate
- Where
- 2 sites in United States
- Volunteers
- 214 people
- Sponsor
- The Cleveland Clinic
Metastatic Pancreatic Cancer, Terminal Cancer
Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancer
The purpose of this study is to evaluate the efficacy of vitamin C in improving the quality of life for metastatic pancreatic cancer patients who are resistant to chemotherapy.
- Trial name
- PTCA199-4 (NCT06018896)
- Testing
- Ascorbate
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Fudan University