Clinical trials: Ascorbic Acid
Pancreatic Cancer
Vitamin C Plus Cordyceps to Quality of Life in Patients With Terminal Stage Pancreatic Cancer
The purpose of this study is to evaluate the efficacy of vitamin C plus herbal medicine in improving the quality of life for metastatic pancreatic cancer patients who are resistant to chemotherapy.
- Trial name
- NCT06598033
- Testing
- VC plus herbal medicine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fudan University
Healthy Children
An Investigator-initiated Trial to Assess the Effectiveness of Three Different Gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy Children
An Open-Label, Three-Arm, Parallel, Investigator-Initiated Trial of Three Different Gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy Children.
- Trial name
- NCT05775237
- Testing
- Curcumin Gummies, Vitamin C Gummies, Multivitamin Gummies
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Pancreatic Cancer
Vitamin C Plus Cordyceps to Chemotherapy Related Anemia in Pancreatic Cancer
The purpose of this study is to evaluate the efficacy of low-dose vitamin C plus herbal medicine on improving the quality of life for metastatic pancreatic cancer patients receiving gemcitabine and nab-paclitaxel chemotherapy.
- Trial name
- NCT06601283
- Testing
- Vitmain C plus herbal medicine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fudan University
Ascorbic Acid, Neurosurgical Procedures
Effect of Vitamin C on Postoperative Pulmonary Complications After Intracranial Tumor Surgery
The goal of this clinical trial is to investigate the effect of perioperative administration of vitamin C on postoperative pulmonary complications, with the aim of providing a safe and effective medication regimen for the…
- Conditions
- Ascorbic Acid, Neurosurgical Procedures, Humans, Ventilator-Induced Lung Injury
- Trial name
- NCT06421688
- Testing
- Ascorbic acid, Saline
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Qianfoshan Hospital
Type 1 Diabetes Mellitus
Effects of Vitamin C and E on Endothelial Function in Adolescent Diabetes
The endothelium is the lining of the blood vessels that helps prevent damage to the vessels. The endothelium does not function as well as it should in adolescents with type 1 diabetes. This causes future diabetes complications.
- Trial name
- NCT02019186
- Testing
- Vitamin C, Vitamin E
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Nationwide Children's Hospital
Sepsis, Septic Shock
Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments
In this clinical trial the effect of early administration of Vitamin C is investigated in patients admitted at the emergency department with sepsis or septic shock.
- Conditions
- Sepsis, Septic Shock, Sepsis, Severe
- Trial name
- c-easie (NCT04747795)
- Testing
- Vitamin C, Normal saline
- Where
- 8 sites in Belgium
- Volunteers
- 301 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Shock, Septic
Vitamin C, Hydrocortisone and Thiamine for Septic Shock
Prior data has shown that both corticosteroids and vitamin C reduce the activation of nuclear factor ƘB (NFƘB), thereby ultimately attenuating the systemic inflammatory response to sepsis/septic shock and augmenting the…
- Trial name
- CORVICTES (NCT03592693)
- Testing
- Combined Vitamin C and Stress-Dose Hydrocortisone
- Where
- 2 sites in Greece
- Volunteers
- 24 people
- Sponsor
- University of Athens
Females, Males
The Effects of Vitamin C on Acute-Exercise in Postmenopausal Females
This study is looking at whether vitamin C can help improve oxidative stress and blood vessel health in females after menopause.
- Conditions
- Females, Males, Menopause, Sedentary
- Trial name
- PM-VitC (NCT07109115)
- Testing
- Vitamin C (Ascorbic Acid)
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Acne Vulgaris
Acne Treatment With Active Oplon's Patches
The purpose of this study was to demonstrate the effect of short treatment with active OPLON patches on Acne.
- Trial name
- NCT01180543
- Testing
- Oplon Active Patch
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Oplon-Pure Science Ltd.
Chronic Pain, Knee Pain Chronic
Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty
Phase II Multicentre, pilot, parallel-group, blinded, 1:1 randomized controlled trial to determine the feasibility of conducting a larger definitive trail of using vitamin C to reduce persistent pain in patients undergoing total…
- Conditions
- Chronic Pain, Knee Pain Chronic, Post Operative Pain
- Trial name
- PROVISION (NCT06123715)
- Testing
- Vitamin C
- Where
- 3 sites in Canada
- Volunteers
- 400 people
- Sponsor
- University Health Network, Toronto
Sepsis
Effect of Intravenous Vitamin C on SOFA Score Among Septic Patients
This study aimed to explore the effect of intravenous (IV) vitamin C on sequential organ failure assessment (SOFA) score among septic patients in intensive care unit (ICU).
- Trial name
- NCT04137276
- Testing
- vitamin C, vitamin B1, vitamin B1
- Where
- Indonesia
- Volunteers
- 33 people
- Sponsor
- Universitas Indonesia
Tissue Modification After Vit c Injection
Effect of Vitamin C on Collagen Production in Comparison to Hereditary Gingival Fibromatosis: Histopathological Study
In this preliminary study, we propose that the intraepidermic injection of vit C can induce quantitative and qualitative modification of the gingival biotype.
- Trial name
- NCT07043985
- Testing
- biopsy
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Badr University
Iron Deficiency, Anemia
The Efficacy of a Local Vitamin-C Rich Fruit (Guava) in Improving Iron Absorption From Mungbean Based Meals and Its Effect on Iron Status of Rural Indian Children (6-10 Years)
Iron deficiency is estimated to affect about one fifth of the world's population, and women and children are among the most severely affected.
- Trial name
- MUGUST_2 (NCT01191463)
- Testing
- Mung Bean Meal, Guava
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Primary Stability of the Implants, Pain
Osteoimplant and Dental Implants Stability
Based on the scientific evidence, the relevance of this subject, we consider this study to be justified, the general or specific objective of which is as follows: 'To evaluate the effect of the administration of Osteoimplant© and…
- Trial name
- OIMP (NCT06657521)
- Testing
- osteoimplant
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Ageing
Exploratory Study on the Role of Vitamin C in Promoting Health in Middle-Aged and Elderly Adults
The purpose of this clinical trial is to understand whether oral vitamin C can help delay the aging of middle-aged and elderly individuals, search for sensitive biomarkers of human aging, and provide new paradigms and scientific…
- Trial name
- VitC-Aging (NCT06794255)
- Testing
- Vitamin C
- Where
- 3 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Diabetes Mellitus, Colonic Diseases
Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients
This trial will compare the tolerance to 2 different methods for colon cleansing before colonoscopy in diabetic patients.
- Trial name
- iDIMEPREP (NCT02297399)
- Testing
- PEG-ascorbate 2L, PEG 4L
- Where
- 2 sites in Spain
- Volunteers
- 158 people
- Sponsor
- Parc de Salut Mar
Restless Legs Syndrome, Kidney Failure, Chronic
Study of Vitamin C, Vitamin E and Their Combination to Treat Restless Legs Syndrome in Hemodialysis Patients
The purpose of this study is to determine whether vitamin C, vitamin E and their combination are effective in the treatment of RLS in hemodialysis patients.
- Trial name
- ShirazUMS (NCT01125033)
- Testing
- Vitamin C & Vitamin E, Vitamin C, Vitamin E
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shiraz University of Medical Sciences
Sepsis, Septic Shock
Clinical Efficacy of Megadose Vitamin C in Sepsis
In this multicenter, randomized, single-blind, placebo-controlled clinical trial. Patients will be randomly assigned to receive Vitamin C or placebo for 4 days or until ICU discharge (whatever come first).
- Trial name
- CEMVIS (NCT05194189)
- Testing
- Vitamin C, 5% glucose injection
- Where
- 4 sites in China
- Volunteers
- 234 people
- Sponsor
- Zhujiang Hospital
Quality of Life
Effect of Colon Delivered Vitamin C on Gut Microbiota and Related Health Biomarkers in Healthy Older Adults
Recent studies have shown that many vitamins, if consumed in high daily dosages or delivered to the colon, can modulate the gut microbiota and their metabolites.
- Trial name
- NCT05598619
- Testing
- Vitamin C
- Where
- Ireland
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Cardiac Arrest
Efficacy of Early Intravenous High-dose Vitamin C in Post-cardiac Arrest Shock.
Among patients admitted after an out-of-hospital cardiac arrest (OHCA) in intensive care unit (ICU), almost two thirds of patients will develop in the first hours a post-cardiac arrest (CA) shock.
- Trial name
- VICEPAC (NCT05817851)
- Testing
- Vitamin C (Laroscorbine) + Vitamin B1 (Bevitine), standard treatment
- Where
- 14 sites in France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier de Bethune