Clinical trials: Asherman Syndrome, active
Asherman's Syndrome, Thin Endometrial Lining
Senescent Endometrial Cells in Patients With Thin Endometrial Lining
The goal of this observational study is to determine if thin endometrial lining that is unresponsive to estrogen might be associated with the presence of senescent cells in patients following long-term use of oral contraceptives.
- Conditions
- Asherman's Syndrome, Thin Endometrial Lining, Cell Senescence
- Trial name
- NCT06450301
- Testing
- Endometrial Biopsy
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Trio Fertility
Asherman Syndrome, Atrophic Endometrium
Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium
This study will assess the use of autologous bone marrow stem cells mobilization using 1,1'-[1,4-phenylenebis-(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane (PLERIXAFOR) as an effective medical therapy for the treatment of…
- Conditions
- Asherman Syndrome, Atrophic Endometrium, Recurrent Implantation Failure
- Trial name
- NCT05343572
- Testing
- Plerixafor
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hugh Taylor
Asherman Syndrome, Intrauterine Adhesion
PREvention of Intrauterine Adhesion After Adhesiolysis With Novel Tri-block deGradable Polymer Film.
PREG2 is a randomized controlled trial that aims to evaluate efficacy in preventing intrauterine adhesion recurrence after hysteroscopic adhesiolysis of a novel intrauterine barrier film named Womed Leaf
- Trial name
- PREG2 (NCT04963179)
- Testing
- Womed Leaf
- Where
- 15 sites in Belgium, China and 5 more
- Volunteers
- 160 people
- Sponsor
- Womed
Asherman Syndrome
CURENDO (Cord-blood Uterine Regeneration Endometrium): Platelet-rich Plasma Therapy Derived From Umbilical Cord Blood for the Treatment of Endometrial Pathologies (Asherman Syndrome / Endometrial Atrophy / Thin Endometrium)
In recent years, platelet-rich plasma (PRP) has emerged as a promising alternative for treating endometrial pathologies that affect the endometrial lining.
- Trial name
- CURENDO (NCT07697924)
- Testing
- Umbilical cord platelet-rich plasma (hUC-PRP)
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Fundación IVI
Endometrium; Atrophy, Intrauterine Synechiae
AD-SVF Therapy for Refractory Endometrial Infertility
The purpose of this study is to initially explore the efficacy of adipose-derived stromal vascular fraction (AD-SVF) therapy in the treatment of refractory endometrial infertility.
- Trial name
- NCT07230600
- Testing
- AD-SVF
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Intrauterine Polyp, Intrauterine Synechiae
Study on the Effective Dose and Safety of Esketamine in Hysteroscopic Surgery Under Monitored Anesthesia Care
Cervical dilation-induced somatic responses remain a critical challenge in ambulatory hysteroscopic surgery. Esketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, exhibits unique analgesic and sedative properties that…
- Trial name
- NCT07034963
- Testing
- Determine the ED50 and ED95 of esketamine, Intravenous the dose of esketamine ED95, Intravenous remifentanil 1μg∙kg-1
- Where
- China
- Volunteers
- 95 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Intrauterine Abnormalities in Infertility, Asherman Syndrome
Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion
The aim of this study was to obtain short- and long-term performance and safety data of cross-linked hyaluronic acid-based adhesion barrier gel used to prevent intrauterine adhesion formation.
- Conditions
- Intrauterine Abnormalities in Infertility, Asherman Syndrome, Intra-uterine Adhesions, Postoperative Adhesion of Uterus
- Trial name
- SEMFERTIL (NCT07160764)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology