Clinical trials: Asperger's Syndrome
Autism Spectrum Disorder, Autism
Mitochondrial Dysfunction in Autism Spectrum Disorder
Researchers at Arkansas Children's Hospital Research Institute are conducting a study about mitochondrial function in children. The study involves up to 5 visits to Arkansas Children's Hospital with fasting blood draws…
- Conditions
- Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
- Trial name
- Mito (NCT02000284)
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Autism Spectrum Disorder, Developmental Delay
A Salivary miRNA Diagnostic Test for Autism
The goal of this study is to validate a panel of miRNAs that distinguish children with autism spectrum disorder (ASD) from their non-ASD peers with a positive MCHAT-R.
- Trial name
- NCT02832557
- Testing
- Salivary collection, Vineland Adaptive Behavior Scale-III Assessment, Medical history questionaire
- Where
- United States
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorders
Mirtazapine Treatment of Anxiety in Children and Adolescents With Pervasive Developmental Disorders
This study will determine the effectiveness of mirtazapine in reducing anxiety in children with autistic disorder, Asperger's disorder and Pervasive Developmental Disorder.
- Trial name
- NCT01302964
- Testing
- Mirtazapine
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorders
Study of Arbaclofen for the Treatment of Social Withdrawal in Subjects With Autism Spectrum Disorders
To explore the efficacy, safety and tolerability of STX209 (arbaclofen) administered for the treatment of social withdrawal in subjects with autism spectrum disorders
- Trial name
- NCT01288716
- Testing
- Arbaclofen
- Where
- 24 sites in United States
- Volunteers
- 150 people
- Sponsor
- Seaside Therapeutics, Inc.
Autistic Disorder, Autism Spectrum Disorder
Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder
This study will investigate and contrast the effects of two psychological treatments for adults with autism spectrum disorder. Cognitive Enhancement Therapy (CET) is a cognitive remediation intervention that aims to help adults…
- Conditions
- Autistic Disorder, Autism Spectrum Disorder, Asperger's Syndrome, Pervasive Developmental Disorder
- Trial name
- Perspectives (NCT00902798)
- Testing
- Cognitive Enhancement Therapy, Enriched Supportive Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Pittsburgh
Asperger Syndrome, Autistic Disorder
Cognitive Behavioural Therapy (CBT) and Recreational Activity for Autism Spectrum Disorders (ASD)
The purpose of this study is to determine if adults with autism spectrum disorder and with normal intelligence improve from 36 sessions (1 calendar year) of group treatment with Cognitive Behavioural Therapy or recreational…
- Conditions
- Asperger Syndrome, Autistic Disorder, Atypical Autism
- Trial name
- NCT01655173
- Testing
- Cognitive behaviour therapy, Recreational activity intervention
- Where
- Sweden
- Volunteers
- 68 people
- Sponsor
- Karolinska Institutet
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Comorbid anxiety disorders affect as many as 80% of youth with autism spectrum disorders, causing substantial distress and impairment over and above the autism spectrum diagnosis alone.
- Trial name
- NCT01177969
- Testing
- Cognitive-Behavioral Therapy, Wait-list
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism Spectrum Disorder, Intellectual Disability
TMS for the Investigation of Brain Plasticity in Autism Spectrum Disorders
The main purpose is to study brain plasticity (the changes that occur in the brain through experience) in individuals with autism spectrum disorder (ASD).
- Trial name
- NCT02836405
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder, Asperger Disorder
Understanding the Effects of Intervention on the Brain in Autism
This study examines how the PEERS (Laugeson \& Frankel, 2010; Laugeson, 2016) social-behavioral intervention affects social relationships and brain development and function in autistic preschoolers, adolescents, and young adults.
- Conditions
- Autism Spectrum Disorder, Asperger Disorder, PDD-NOS, Autism
- Trial name
- NCT02680015
- Testing
- PEERS
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Marquette University
Asperger's Disorder
Janssen Asperger's MRS (Magnetic Resonance Spectroscopy Risperidone Study
This study will be an open-label, 12-week trial of risperidone in subjects with Asperger's Disorder, according to Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) Criteria.
- Trial name
- NCT00352196
- Testing
- Risperidone, Magnetic Resonance Spectroscopy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Augusta University
Asperger Syndrome, Autism Spectrum Disorder
Psychopathological Differences Between Asperger Syndrome and Schizotypal Disorder in an Adult Sample
The purpose of this study is to identify psychopathology (psychiatric symptoms) that can differentiate between Schizotypal Disorder (SD) and Asperger Syndrome (normal IQ, no language impairment Autism Spectrum Disorder) (AS) in…
- Conditions
- Asperger Syndrome, Autism Spectrum Disorder, Schizotypal Personality Disorder
- Trial name
- NCT02800681
- Testing
- Expert panel evaluation, Semi-structured psychopathological interviews, Self-administered rating scales
- Where
- 2 sites in Denmark
- Volunteers
- 59 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
DCild Development Disorders, Pervasive, Autistic Disorder
A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Children With Autistic Disorder and Other Pervasive Developmental Disorders (PDD)
The purpose of the study is to evaluate the effectiveness of an oral solution of risperidone (an antipsychotic medication) versus placebo in the treatment of behavioral symptoms in children with Pervasive Developmental Disorders…
- Conditions
- DCild Development Disorders, Pervasive, Autistic Disorder, Developmental Disabilities, Asperger Syndrome
- Trial name
- NCT00261508
- Testing
- risperidone
- Volunteers
- 80 people
- Sponsor
- Janssen-Ortho Inc., Canada
Autism Spectrum Disorder, Asperger Syndrome
Milnacipran in Autism and the Functional Locus Coeruleus and Noradrenergic Model of Autism
Autism Spectrum Disorders (ASD) include Autistic disorder, Asperger's syndrome and Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS). These are developmental disorders beginning prior to three years of age.
- Conditions
- Autism Spectrum Disorder, Asperger Syndrome, Aspergers Syndrome
- Trial name
- NCT01337700
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Montefiore Medical Center
Autism Spectrum Disorder, Autism
Cognitive-Behavioral Therapy for Children With High-Functioning Autism Spectrum Disorder and Anxiety
Many children and adolescents with autism spectrum disorder (ASD) experience high levels of anxiety which can further inhibit their ability to master developmental tasks such as succeeding in school and developing and maintaining…
- Conditions
- Autism Spectrum Disorder, Autism, Asperger Syndrome, PDD-NOS
- Trial name
- NCT01187784
- Testing
- Coping Cat cognitive-behavioral therapy for anxious youth
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Alliant International University
Autistic Disorder, Asperger Syndrome
Study of Aripiprazole to Treat Children and Adolescents With Autism
The purpose of this open label study in children and adolescents is to examine the acute and long-term effects of aripiprazole on problem behaviors associated with autism spectrum disorders and development in areas which appear…
- Conditions
- Autistic Disorder, Asperger Syndrome, Autism Spectrum Disorder
- Trial name
- PAIRS (NCT00619190)
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder, Autistic Disorder
A Folinic Acid Intervention for Autism Spectrum Disorders
Researchers at Arkansas Children's Hospital Research Institute are conducting a study looking at the effects of Folinic Acid on language in Autism Spectrum Disorder and language impairment. The study has 3 phases.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Autism, Asperger's Syndrome
- Trial name
- NCT01602016
- Testing
- Folinic Acid
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Arkansas
Autism, Autism Spectrum Disorder
Neural and Behavioral Outcomes of Social Skills Groups in Children With Autism Spectrum Disorder (ASD)
The purpose of this study is to compare two different treatment approaches to social skills groups for high-functioning children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT01190917
- Testing
- Cognitive Behavioral Therapy (CBT), Play Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Schizophrenia, Schizoaffective Disorder
Study of Lurasidone in Treating Antipsychotic Naive or Quasi-Naive Children and Adolescents
The overarching purpose of this pilot study is to collect preliminary data regarding the variability of weight gain associated with lurasidone (Latuda©) treatment of antipsychotic naive children and adolescents in order to inform…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychosis NOS
- Trial name
- NCT01731119
- Testing
- Latuda©
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of North Carolina, Chapel Hill
Fragile X Syndrome, Autism Spectrum Disorder
Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders
Fragile X Syndrome (FXS) is a complex neurodevelopmental disorder caused by a mutation on the X chromosome. Scientists have investigated FXS extensively in both humans and animals.
- Conditions
- Fragile X Syndrome, Autism Spectrum Disorder, Autistic Disorder, Asperger Syndrome
- Trial name
- ENTRAIN (NCT06227780)
- Testing
- Alpha Auditory Entrainment
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autistic Disorder, Asperger Syndrome
CBT for Comorbid Anxiety Disorders in Children With Autism, Asperger Syndrome, or PDD-NOS
This study is designed to examine the efficacy of a cognitive behavioral therapy (CBT) program for treating anxiety symptoms, social problems, and adaptive behavior deficits in children with autism spectrum disorders.
- Conditions
- Autistic Disorder, Asperger Syndrome, Anxiety Disorders
- Trial name
- BIACA (NCT00280670)
- Testing
- Cognitive-behavioral therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles