Clinical trials: Aspiration, Respiratory
Pulmonary Embolism, Dyspnea
Ventilation/Perfusion PET/CT With Galligas and 68Ga-MAA for Regional Lung Function Assessment After Pulmonary Embolism
In patients with pulmonary embolism (PE), after three or six months of anticoagulation, persistent dyspnea and impairment of quality of life are observed in at least 30% of cases.
- Trial name
- EOLE (NCT05103670)
- Testing
- Ventilation/Perfusion PET/CT with Galligas and 68Ga-MAA
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Brest
High Flow Oxygen Therapy, ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION
High-Flow Nasal Oxygyen Therapy During Sedated Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration(EBUS-TBNA)
This study aims to evaluate the effects of high-flow nasal oxygen therapy on respiratory complications, blood gas parameters, and post-procedural recovery in patients undergoing sedated endobronchial ultrasound-guided…
- Conditions
- High Flow Oxygen Therapy, ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Sedation, Sedation Complication
- Trial name
- NCT07760727
- Testing
- High-Flow Nasal Oxygen Therapy, Conventional Oxygen Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Pneumonia, Aspiration
Risk of Respiratory Complications Following Gastrointestinal Endoscopy Under Monitored Anesthesia Care
The purpose of this study is to investigate the incidence of respiratory complications after gastroenteroscopy, and establish a Logistic regression model to analyze the related risk factors of respiratory complications.
- Trial name
- NCT06705894
- Where
- China
- Volunteers
- 10,313 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Respiratory Distress Syndrome, Prematurity
Influence of Flow Rate Change on CO2 Levels During High Flow Nasal Ventilation (HFNV) in Preterm Infants.
Background Preterm infants often need respiratory support. HFNV is a non-invasive method with benefits over CPAP, such as reduced nasal trauma and improved feeding. Aim Study the impact of low (2 LPM) vs.
- Conditions
- Respiratory Distress Syndrome, Prematurity, Non Invasive Ventilation
- Trial name
- NCT06622902
- Testing
- change flow from 6 to 2 LPM. Follow TcCO2 for 3 hours, change flow from 2 to 6 LPM. Follow TcCO2 for 3h
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Rambam Health Care Campus
COVID-19
The Safety, Tolerability, and Pharmacokinetics of Inhaled TLC19 in Healthy Volunteers
Phase 1 randomized, vehicle-controlled, blinded study to assess the safety, tolerability, and PK of single ascending doses of inhaled TLC19 in healthy volunteer subjects.
- Trial name
- NCT04697654
- Testing
- TLC19, TLC19 Vehicle
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taiwan Liposome Company
Systemic Lupus Erythematosus
Respiratory Function, Physical Activity and Fatigue in SLE
Increasing awareness of possible pulmonary involvement in patients with systemic lupus erythematosus (SLE) will enable earlier diagnosis of the disease and minimize damage accumulation.
- Trial name
- NCT07193745
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Melis Usul
Aspiration, Respiratory, Cerebral Palsy
Gastric Volume in the Fasted Pediatric Cerebral Palsy Patients
In children with cerebral palsy, the gastric volume is measured through ultrasound after fasting before surgery to evaluate whether the risk of aspiration is higher than that of the general population.
- Trial name
- NCT04918277
- Testing
- Assessment of gastric volume
- Volunteers
- 38 people
- Sponsor
- Seoul National University Bundang Hospital
Respiration
Substantial Equivalence Study for Kai Sensors RSpot Non-Contact Respiratory Rate Spot Check
The purpose of this study is to determine whether the respiratory rate provided by the Kai Sensors RSpot 100 Non-Contact Respiratory Rate Spot Check is as accurate as that provided by the Welch Allyn Propaq Encore model 242 and…
- Trial name
- NCT00827905
- Testing
- RSpot Non-Contact Respiratory Rate Spot Check
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kai Medical, Inc.
COVID-19
Inhaled Ivermectin and COVID-19
Coronavirus disease-19 is global healthcare crisis. Till May 20, 2020, there were approximately 4,789,205 cases and 318,789 related mortalities were identified globally.
- Trial name
- CCOVID-19 (NCT04681053)
- Testing
- Ivermectin Powder
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cerebral Palsy
A Gamified Breathing and Postural Awareness Education Model for Children With Cerebral Palsy
This project aims to develop an accessible, learning-oriented model based on gamified breathing and posture training that emphasizes active participation for children with cerebral palsy (CP), their families, and educators.
- Trial name
- NEFES-CP (NCT07681947)
- Testing
- N.E.F.E.S.-CP Education Model
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yeditepe University
Pulmonary Disease, Chronic Obstructive, Hyperoxia
Effective High Aerobic Intensity Endurance Training Regimes in Chronic Obstructive Pulmonary Disease (COPD) Patients
4 times 4 minutes interval training with and without hyperoxia is more effective than low intensity endurance training.
- Trial name
- NCT00658853
- Testing
- 4 times 4 minutes high aerobic intensity one leg cycling
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Norwegian University of Science and Technology
Aspiration Pneumonia, Tracheostomy Complication
Intra-laryngeal Implant for Treatment of Chronic Aspirations
This study evaluates the medical device Newbreez LD is designed to protect the lower airways from saliva, liquids and food aspirations in tracheotomized patients suffering from chronic aspirations that require specific care and…
- Trial name
- NCT03325725
- Testing
- NewBreez LD intra-laryngeal implant
- Where
- 2 sites in France
- Sponsor
- ProTiP Medical
Respiration Disorders
Respiratory Monitoring System That Detects & Predicts OIRD
This study is being conducted to evaluate the ability of the Respiratory Monitoring System (RMS) to detect and predict opioid induced respiratory depression (OIRD) in post-operative surgical patients managed with opioid…
- Trial name
- RTM-NIH-SBIR-2 (NCT07217197)
- Testing
- Study to evaluate a Respiratory Monitoring System (RMS) with a Tracheal Sound Sensor (TSS) for detecting and predicting opioid induced respiratory Depression (OIRD).
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Thomas Jefferson University
Multiple Sclerosis
Proprioceptive Neuromuscular Facilitation in Multiple Sclerosis
Multiple Sclerosis (MS) is an autoimmune central nervous system disease characterized by inflammation, demyelination, and axonal degeneration.
- Trial name
- NCT05342025
- Testing
- PNF, Breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biruni University
Malignant Neoplasms of Respiratory and Intrathoracic Organs, Lung Neoplasm
Radial-Probe Endobronchial Ultrasound in Detecting Atelectasis in Patients Undergoing Peripheral Bronchoscopy
This trial studies how well radial-probe endobronchial ultrasound works in detecting the complete or partial collapse of the lung in patients undergoing peripheral bronchoscopy.
- Trial name
- NCT03523689
- Testing
- Bronchoscopy, Radial Probe Endobronchial Ultrasound
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- M.D. Anderson Cancer Center
Nitrous Oxide, Dentistry
Demand-Driven Method for Gas Delivery in a Dental Setting
This study compares two methods of gas delivery in a dental setting: 1) demand-driven (DD) and 2) free-flow (FF). Nitrous oxide and oxygen sedation (NOS) is a common form of minimal sedation for adult and paediatric patients…
- Conditions
- Nitrous Oxide, Dentistry, Drug Delivery System, Comfort
- Trial name
- NCT04305990
- Testing
- Demand-driven delivery method, Free-flow delivery method
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Invasive Aspergillosis
Concentrations of Voriconazole in Blood and BAL-fluid After Inhalation and Oral Administration
Concentrations of voriconazole in pulmonary epithelial lining fluid and in serum are compared after inhalation of 40 mg voriconazole b.i.d.
- Trial name
- NCT02396225
- Testing
- Voriconazole
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Cardiovascular Diseases, Coronary Artery Disease
The Effect of Continued Mechanical Ventilation on the Occurrence of Myocardial Ischemia
The goal of this study is to examine the influence of mechanical ventilation on the occurrence of myocardial ischemia in patients undergoing endo-CABG.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Myocardial Ischemia, Hypoxia
- Trial name
- VENTMICS-II (NCT05417217)
- Testing
- Discontinued ventilation, Continued ventilation
- Where
- Belgium
- Volunteers
- 165 people
- Sponsor
- Jessa Hospital
ARDS
Electrical Impedance Tomography-Derived Dorsal Recruitment-to-Inflation Ratio Identifies PEEP Responsiveness and Risk Phenotypes in ARDS
In the treatment of critically ill patients, mechanical ventilation is a key link, and appropriate mechanical ventilation strategies can open the alveoli and improve oxygenation, while inappropriate mechanical ventilation can…
- Trial name
- NCT06823804
- Testing
- Electrical Impedance tomography Monitoring
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Ruijin Hospital
COVID-19
Tele-Rehabilitation in Individuals With Covid-19
Coronavirus Disease (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-cov-2). This study was planned as a single-blind randomized controlled pilot study to compare the…
- Trial name
- NCT05305638
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
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