Clinical trials: Aspiration, Respiratory
Respiratory Distress Syndrome
Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure
The investigators have recently demonstrated the beneficial effects of combined high-frequency oscillation (HFO) and tracheal gas insufflation (TGI) on the respiratory physiology [1,2] of patients with severe acute respiratory…
- Trial name
- HFO-TGI-2 (NCT00637507)
- Testing
- High-frequency Oscillation and Tracheal Gas Insufflation
- Where
- 2 sites in Greece
- Volunteers
- 124 people
- Sponsor
- University of Athens
Acute Respiratory Distress Syndrome, Mechanical Ventilation
Physiological Studies in the Prone Position in Patients With ARDS
The purpose of this study is to observe the changes of physiological indicators such as ventilation and oxygenation in the prone position of ARDS patients, to observe the change trend of each patient's indicators, and to observe…
- Conditions
- Acute Respiratory Distress Syndrome, Mechanical Ventilation, Prone Positioning
- Trial name
- NCT06586736
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Respiration, Artificial, Respiratory Insufficiency
24-Hour NAVA Ventilation in Acute Respiratory Failure
Neurally Adjusted Ventilatory Assist (NAVA) is a new mode of mechanical ventilation that is controlled by the electrical activity of the diaphragm (EAdi).
- Trial name
- NCT00583037
- Testing
- Neurally Adjusted Ventilatory Assist (NAVA)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Unity Health Toronto
CSF Circulation
Influence of Yogic Breathwork on CSF Circulation
The purpose of this research study is to determine the influence of yoga breathing practices on cerebrospinal fluid (CSF) circulation, and to find out primarily if a regular practice of 8-week yoga breathing would enhance CSF…
- Trial name
- CSF (NCT03858309)
- Testing
- Breathing Group 1, Breathing Group 2
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Acute Viral Bronchiolitis
Effects of Rhinopharyngeal Retrograde Clearance in Children With Acute Viral Bronchiolitis
The purpose of this study is to compare the immediate effects of retrograde rhinopharyngeal clearance with nasopharyngeal aspiration in children admitted with acute viral bronchiolitis.
- Trial name
- NCT02460614
- Testing
- Rhinopharyngeal clearance, Aspiration, 0.9% saline
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Aspiration Pneumonia
Early Stop(Ruling) of the Antibiotic Treatment During Pneumopathies d' Inhalation
The two most common consequences resulting from aspiration are chemical pneumonitis and bacterial aspiration pneumonia. Both entities present with comparable clinical signs and symptoms.
- Trial name
- APAPI (NCT03763799)
- Testing
- PCR-based microbiological diagnosis strategy, Standard microbiological diagnosis strategy
- Where
- 2 sites in France
- Volunteers
- 266 people
- Sponsor
- University Hospital, Lille
Postoperative Cardiorespiratory Failure
Hypertonic Saline-hetastarch in Cardiac Surgery
Cardiopulmonary bypass(CPB) is associated with increased fluid extravasation and edema formation. A continuous infusion of a mixture of hypertonic saline/hydroxyethyl starch (HSH)during CPB reduced fluid extravasation and total…
- Trial name
- HH (NCT00469716)
- Testing
- Hypertonic saline (7.2%) hetastarch (6 %)(200/0.5)
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Lung Cancer
Trial of Endobronchial Ultrasound Guided Fine Needle Aspiration Techniques
Endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TBNA) techniques have not been well studied. The investigators will conduct a randomized study comparing the diagnostic yield and specimen quality of…
- Trial name
- NCT01741571
- Testing
- EBUS guided FNA with and without suction
- Where
- Lebanon
- Volunteers
- 32 people
- Sponsor
- American University of Beirut Medical Center
PET/CT, COVID-19
Study for Quantitative Analysis of the Recovered COVID-19 Patients by 18F-FDG-PET/CT
In this study, clinically cured patients with severe COVID-19 were used to evaluate the therapeutic effect of COVID-19 and the recovery and health status of patients over time with highly sensitive PET/CT imaging technology.
- Conditions
- PET/CT, COVID-19, Respiratory Function, Inflammatory Lesions
- Trial name
- NCT04519255
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Foreign Body Aspiration, Blood Gas, Bronchoscopy
Comparison of Patients With and Without Foreign Body Aspiration After Bronchoscopy.
To compare patients under 5 years of age with foreign body aspiration and without foreign body aspiration with radiological and blood gas results.
- Trial name
- NCT04467307
- Testing
- Rigit bronchoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Pneumonia
Venticute in Patients With Pneumonia or Aspiration of Gastric Contents and Intubation/Ventilation/Oxygenation Impairment (BY2001/M1-007)
Study to demonstrate that administration of Venticute increases survival of patients with pneumonia or aspiration of gastric contents leading to intubation, mechanical ventilation, and severe oxygenation impairment.
- Trial name
- NCT00074906
- Testing
- Venticute
- Where
- 92 sites in Australia, Austria and 15 more
- Volunteers
- 1,200 people
- Sponsor
- Takeda
Respiration, Artificial, Positive-Pressure Respiration
VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU
Patients undergoing major non-cardiac surgery may require postoperative mechanical ventilation and transfer from the operating room to the intensive care unit (ICU).
- Conditions
- Respiration, Artificial, Positive-Pressure Respiration, Postoperative Complications (Cardiopulmonary), Postoperative Complications
- Trial name
- VENTICRIT (NCT07646249)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Patient Involvement
The Effect of Chest Physiotherapy Methods Applied Before Aspiration on Respiratory Characteristics
Physiotherapy is one of the most frequently used supportive treatments in intensive care units due to its positive effects on critically ill patients.
- Trial name
- NCT06277817
- Testing
- expiratory rib cage compression, percussion vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Inonu University
Dysphagia, Respiratory Tract Infections
Using Plain Water With Oral Care to Increase Hydration for Long Term Care Residents With Disordered Swallowing
The Frazier Free Water Protocol (FFWP) using plain, thin (unmodified) water is an accepted method to increase fluid intake and hydration in older adults with disordered swallowing and dementia.This study aims to take an…
- Trial name
- FFWP (NCT03672552)
- Testing
- FFWP and Improved Oral Care
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Memorial University of Newfoundland
Sternotomy
The Benefit of Preparation in Respiratory Physiotherapy Before a Sternotomy in the Context of Cardiac Surgery
The sternotomy has some influence on the respiratory system after cardiac surgery, considerably increasing the risk of perioperative and postoperative breathing.
- Trial name
- NCT06153550
- Testing
- preparation in Respiratory Physiotherapy
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Post-Lung Transplantation Bronchiectasis
Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant
The purpose of this research is to study the effect of training the inspiratory muscles (i.e. the muscle that allow you to breath-in) on exercise capacity, quality of life, and short-term clinical outcomes in patients post lung…
- Trial name
- NCT04783155
- Testing
- POWERBreathe Plus®, Cardiopulmonary rehabilitation post lung transplant
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Meconium Aspiration Syndrome
CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)
When babies are stressed in the womb, they sometimes pass meconium in the amniotic fluid. When this happens, they may swallow the meconium-stained fluid into their lungs which may cause them to have poor oxygen levels and require…
- Trial name
- CAPUCINO (NCT06972108)
- Testing
- Caffeine citrate
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Respiratory Insufficiency
"Inspiratory Muscle Training in Older Women"
Objective: To evaluate the effectiveness of two protocols of inspiratory muscle training (IMT) in older women to improve respiratory strength, spirometric parameters and dyspnea.
- Trial name
- NCT03827356
- Testing
- Inspiratory muscle trainer (IMT)
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Chronic Obstructive Pulmonary Disease
Impact of Muscle Afferent Feedback During Exercise in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Recently, direct evidences point to the contributing role of peripheral muscle fatigue in exercise tolerance among patients with COPD.
- Trial name
- NCT01522729
- Testing
- Fentanyl
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Laval University
Sickle Cell Disease
Lung Ultrasound in Pediatric Acute Chest Syndrome
Sickle-cell disease is a common disease with serious complications, in particular acute chest syndrome (ACS), which can be life threatening.
- Trial name
- Lupacs (NCT06497153)
- Testing
- lung ultrasound
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris