Clinical trials: Aspiration, Respiratory
Respiratory Function
Acute and Long-Term Effects of Integrated Myofascial Release Therapy on Respiratory Function in Healthy Adults
This study will investigate the immediate and longer-term effects of integrated myofascial release therapy on breathing-related outcomes in healthy adults.
- Trial name
- EMGT-RESP (NCT07822139)
- Testing
- Other
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Acid Aspiration Syndrome
Detection of Silent Aspiration Events Utilizing pH/Impedance Probes in Hospitalized Patients
Monitoring and quantification of reflux events in high risk critically ill inpatients and lower risk general medical/surgical inpatients, with comparison to relevant clinical variables.
- Trial name
- NCT02720029
- Testing
- pH/impedance monitor
- Sponsor
- Vanderbilt University
COVID-19, SARS-CoV2 Infection
Phase 1 Trial of ChAd68 and Ad5 Adenovirus COVID-19 Vaccines Delivered by Aerosol
This is a phase 1 study in healthy volunteers who have received at least three doses of an mRNA COVID-19 vaccine, to evaluate the safety and immune responses that develop in the blood and lungs following the administration by…
- Trial name
- NCT05094609
- Testing
- Ad5-triCoV/Mac, ChAd-triCoV/Mac
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- McMaster University
Respiration, Artificial, Epidemiology
Mechanical Ventilation Epidemiology in Argentina.
How is the epidemiology of mechanically ventilated patients in the intensive care units of Argentina?
- Trial name
- EpVAr2019 (NCT04107467)
- Where
- 154 sites in Argentina
- Volunteers
- 950 people
- Sponsor
- Argentinian Intensive Care Society
Bronchiectasis Adult, Yoga
Effects of an Online Yoga Program on Exercise Capacity and Quality of Life in Bronchiectasis Patients
Bronchiectasis is a chronic lung disease characterized by persistent cough, sputum production, shortness of breath, and recurrent infections, which can reduce physical capacity and quality of life.
- Trial name
- YOGA-BR (NCT07540936)
- Testing
- Yoga Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Medipol University Hospital
Cystic Fibrosis
Evaluation of the Safety and Tolerability of Inhaled Nitric Oxide to Subjects With Cystic Fibrosis
Cystic Fibrosis is defined as a genetic disorder affecting approximately 100,000 individuals worldwide. CF is caused by mutations in the CF Transmembrane Conductance Regulator (CFTR) gene.
- Trial name
- NCT01958944
- Testing
- Nitric oxide
- Where
- 2 sites in Israel
- Volunteers
- 9 people
- Sponsor
- Beyond Air Inc.
Oxygen Consumption, Sevoflurane
Oxygen Consumption and Sevoflurane Uptake Based on Physiological Dead Space Estimation
In this study, the investigators will evaluate whether the delivered fraction of oxygen (O2) and sevoflurane administered through a a closed circuit and calculated on the basis of the estimations of O2 consumption (VO2) and…
- Conditions
- Oxygen Consumption, Sevoflurane, Anesthetics, Inhalation, Surgery
- Trial name
- NCT05511584
- Testing
- VO2 estimation, SEVOup estimation
- Where
- Spain
- Volunteers
- 17 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Lung Disease, Inflammation
Study of Biologic Materials From the Mediastinal Lymph Nodes From Patients With Lung Disease.
The purpose of this protocol is to obtain biologic materials from the mediastinal lymph nodes from patients with lung disease and mediastinal lymph node involvement in order to: (1) develop a better understanding of the cause and…
- Conditions
- Lung Disease, Inflammation, Lung Cancer, Sarcoidosis
- Trial name
- NCT02168036
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Weill Medical College of Cornell University
Asthma, Bronchial, Bronchial Asthma
Dose Response of Inhaled Tacrolimus in Patients With Moderate Persistent Asthma
This study will evaluate the efficacy and safety of tacrolimus in patients with asthma.
- Trial name
- NCT00189787
- Testing
- tacrolimus
- Where
- 49 sites in Bulgaria, Czechia and 5 more
- Volunteers
- 370 people
- Sponsor
- Astellas Pharma Inc
Stress Disorders, Post-Traumatic, Depression
Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Mechanical Ventilation - Effects on PTSD
Through many years, the standard care has been to use continuous sedation of critically ill patients during mechanical ventilation.
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Anxiety
- Trial name
- NCT02040649
- Testing
- Non-sedation, Control, sedation (propofol, midazolam)
- Where
- Denmark
- Volunteers
- 205 people
- Sponsor
- Palle Toft
Critical Illness
Alpha 2 Agonists for Sedation to Produce Better Outcomes From Critical Illness (A2B Trial)
Many patients in intensive care (ICU) need help to breathe on a breathing machine and need pain killers and sedatives to keep them comfortable and pain free.
- Trial name
- A2B (NCT03653832)
- Testing
- Dexmedetomidine, Clonidine, Propofol
- Where
- 38 sites in United Kingdom
- Volunteers
- 1,404 people
- Sponsor
- University of Edinburgh
Oral Infection, Ventilator-associated Pneumonia
Evaluating the Effectiveness of the Tongue Cleaner in Critical Patients
The concern with oral infection and its systemic repercussions is old, many studies have been undertaken to establish this relationship more precisely.
- Trial name
- NCT01294943
- Testing
- Tongue cleaner
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Inhalation Pneumonia
Effect of Diluent Volume on Colistin Inhalation Therapy
The aim of this study is to investigate the impact of different diluent volumes for the same dosage of colistin in mechanically ventilated respiratory patients receiving colistin inhalation therapy.
- Trial name
- NCT06230614
- Testing
- Colistin 1 MU in normal saline 1 ml, Colistin 1 MU in normal saline 2 ml
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fu Jen Catholic University
Lung Cancer, Mediastinal Lymphadenopathy
Capillary Versus Suction Needle Aspiration for Endobronchial Ultrasound (EBUS) Biopsies.
Endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration is a procedure used to obtain tissue samples (biopsies) of lymph nodes near the airways or of lung tumours growing in close proximity to the airways.
- Conditions
- Lung Cancer, Mediastinal Lymphadenopathy, Thoracic Cancer
- Trial name
- CAPSUNN-EBUS (NCT04306614)
- Testing
- Endobronchial Ultrasound guided Transbronchial Fine Needle Aspiration
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- Western University, Canada
Pediatrics, Critical Care
Safety and Efficacy of Emergency On-call Respiratory Physiotherapy Services in the Paediatric Intensive Care Unit
Emergency on-call respiratory physiotherapy cover for children in intensive care is frequently provided by physiotherapists who ordinarily work in non-respiratory areas.
- Conditions
- Pediatrics, Critical Care, Respiration, Artificial
- Trial name
- NCT01999426
- Testing
- Airway clearance intervention
- Where
- United Kingdom
- Volunteers
- 93 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Anesthesia
Different Low-flow Sevoflurane Anesthesia Techniques
After reaching 1 MAC level with 4 lt / min fresh gas flow and 2.5% sevoflurane concentration in the initial stage in 35 patients, anesthesia maintenance will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane…
- Trial name
- NCT04743193
- Testing
- 2.5 %sevoflurane, 8% sevoflurane low flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Ventilation
BASKA Laryngeal Mask Airway in Either Volume or Pressure Controlled Ventilation in Laparoscopic Cholecystectomy
this study will be undertaken to compare the efficacy of BASKA mask in volume controlled and pressure controlled ventilation in laparoscopic cholecystectomy.
- Trial name
- NCT03610126
- Testing
- volume controlled ventilation, pressure controlled ventilation
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Neonatal Resuscitation, Apnea Neonatal
Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates
Many extremely premature infants require immediate help with breathing after birth. Positive pressure ventilation (PPV) using a device called a T-piece resuscitator is a common method.
- Trial name
- MVP (NCT06849596)
- Testing
- Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 780 people
- Sponsor
- Michelle Baczynski
Meconium Aspiration Syndrome
Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome
Meconium aspiration syndrome (MAS) is an important cause of severe respiratory failure in newborn infants. Treatment for MAS is mainly supportive but surfactant therapy might change the course of the disease.
- Trial name
- NCT02041546
- Testing
- Lung lavage with surfactant, Bolus surfactant
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Dysfunctional Breathing
Investigation of the Relationship Between Dysfunctional Breathing and Physical Fitness Parameters in Healty Adults
This observational study aims to investigate the relationship between dysfunctional breathing and physical fitness parameters in healthy adults aged 18-35.
- Trial name
- DISFIT (NCT06943027)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Elif Tunç
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.