Clinical trials: Aspiration, Respiratory
Stroke
Respiratory Functions and Muscle Strength, Trunk Control, Functional Capacity and Independence in Hemiplegic Patients
The aim of this study was to invastigate the relationship between respiratory functions and respiratory muscle strength with trunk control, functional capacity and functional independence in hemiplegic patients after stroke.
- Trial name
- NCT05290649
- Testing
- clinical assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Halic University
Pneumonia, Aspiration
Preliminary Study on the Clinical Application Value of "Showering Cells" in Diagnosing Aspiration Pneumonia
Study Design and Participants: This single-center, retrospective case-control study enrolled adult patients (18-100 years) hospitalized in the RICU of the Chinese PLA General Hospital between January 2018 and December 2024, who…
- Trial name
- NCT07707206
- Where
- China
- Volunteers
- 430 people
- Sponsor
- Chinese PLA General Hospital
Ventilator Associated Pneumonia, Aspiration
Ventilator Aspiration With PneuX (PneuX vs Standard Care Feasibility RCT)
This is a single centre, open-label, feasibility randomised controlled trial. The study aims to assess the feasibility of conducting an RCT to compare the PneuX ETT with standard care in hospitalised patients requiring mechanical…
- Conditions
- Ventilator Associated Pneumonia, Aspiration, Infections, Ventilator Lung
- Trial name
- VAP-X (NCT05410106)
- Testing
- PneuX Endotracheal Tube, Standard care (Taperguard, Covidien)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cardiff and Vale University Health Board
Respiratory Distress Syndrome, Adult, Respiration, Artificial
PEEP-induced Changed in RRI as Physiological Background of Ventilator-induced Kidney Injury
The renal Doppler resistive index (RRI) is a noninvasive tool that has been used to assess renal perfusion in the intensive care unit (ICU) setting. Many parameters have been described as influential on the values of renal RI.
- Conditions
- Respiratory Distress Syndrome, Adult, Respiration, Artificial, Acute Kidney Injury
- Trial name
- PRE-VIKI (NCT03969914)
- Testing
- PEEP changes
- Where
- 2 sites in Italy
- Volunteers
- 105 people
- Sponsor
- Università degli Studi di Ferrara
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 1 of 7)
NOTE: This is the first of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882516
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Mechanical Ventilation, Critical Illness
Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)
This is a randomized controlled trial to compare propofol to dexmedetomidine for prolonged sedation (> 24 hours) in critically ill patients who require mechanical ventilation.
- Trial name
- NCT01059929
- Testing
- Dexmedetomidine, Propofol, Fentanyl
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Chicago
Anaesthesia Induction
Duration of Anaesthesia Induction in Paediatric Patients: Prospective Observational Trial
Intravenous anaesthesia induction is nowadays considered as gold standard, mainly because of the possibility of the rapid therapeutic intervention while having secured i.v. line.
- Trial name
- Induration (NCT04527757)
- Testing
- Inhalation induction, Intravenous induction
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- Brno University Hospital
Healthy Adult Participants
Validity and Reliability of the Turkish Version of the 'Breathing Vigilance Questionnaire'
In the literature, assessment questionnaires related to dyspnea measure beliefs about breathing-related symptoms but do not directly measure breath awareness.
- Trial name
- Breathe-VQ (NCT07544472)
- Testing
- Survey using a questionnaire.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
Pulmonary Cancer, Surgery
Effect of SMS Use on Postoperative Respiratory and Cough Exercise Compliance
Aim: This randomized controlled trial study aimed to evaluate the effect of SMS use on compliance with postoperative breathing and coughing exercises and patient satisfaction in patients undergoing pulmonary lobectomy for lung…
- Trial name
- NCT05915221
- Testing
- SMS
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Trakya University
Asthma
Environmental Intervention Versus Standard Care to Reduce Pharmacologic Therapy for Asthma
Exposure to household allergens is a major contributor to asthma symptoms. Aggressive measures to reduce household allergens has the potential to reduce asthma symptoms and the need for medications to control asthma.
- Trial name
- ERA (NCT01593111)
- Testing
- Environmental Intervention
- Where
- 2 sites in United States
- Volunteers
- 243 people
- Sponsor
- Columbia University
Ventilator Weaning, Respiration, Artificial
Time Course of Neuro-ventilatory Efficiency During a Spontaneous Breathing Training
The TONES trial aims to evaluate the neuroventilatory efficiency (NVE = tidal volume / peak voltage of diaphragm contraction) measured during a zero-assist manoeuvre (ZAM, i.e. with PEEP but without pressure support).
- Conditions
- Ventilator Weaning, Respiration, Artificial, Respiratory Muscles, Respiratory Failure
- Trial name
- TONES (NCT05380687)
- Testing
- Inspiratory hold, Expiratory hold, Ultrasound of respiratory muscles
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- University Hospital, Antwerp
Chest Tube Removal
Clinical Trial Evaluating the Optimal Technique for Chest Tube Removal
There are two commonly used methods to remove chest tubes following thoracotomy. One is to remove the chest tube at maximum inspiration, (patient is asked to take a deep breath in and hold it), and the other is to pull the chest…
- Trial name
- NCT00873587
- Testing
- Chest tube pull on inspiration, Expiration
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Chronic Obstructive Pulmonary Disease
The Study Will Evaluate the Effect of AZD9164 in Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory condition with deteriorating lung function over the years. Patients with COPD experience symptoms of shortness of breath, cough and sputum production.
- Trial name
- LaCrossE (NCT00939211)
- Testing
- AZD9164, Tiotropium
- Where
- 3 sites in Sweden
- Volunteers
- 25 people
- Sponsor
- AstraZeneca
Type 1 Diabetes Mellitus
INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes
INHALE-1st is a Phase 2, single-arm, multi-center, clinical study evaluating the safety and efficacy of Afrezza in combination with subcutaneously-injected basal insulin (BI) for youth 6 to <18 years old with newly diagnosed…
- Trial name
- INHALE-1st (NCT07224321)
- Testing
- Technosphere Insulin, Basal insulin
- Where
- 10 sites in United States
- Volunteers
- 100 people
- Sponsor
- Mannkind Corporation
Stress Disorders, Post-Traumatic
Efficacy Study of Mindfulness-Based Exercise for Posttraumatic Stress Disorder (PTSD)
This study will explore the relationship between changes in plasma cortisol and symptom reduction resulting from individuals with posttraumatic stress disorder (PTSD) participating in an 8-week program of mindfulness-based…
- Trial name
- NCT01462045
- Testing
- Mindfulness-based exercise
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Electric Impedance Tomography, Stress Echocardiography
Stress Echo and Electric Impedance Tomography (EIT) Pilot Study
Electric Impedance Tomography (EIT) is a technique based on the injection of small currents and voltage measurements using electrodes on the skin surface generating cross-sectional images representing impedance change in a slice…
- Conditions
- Electric Impedance Tomography, Stress Echocardiography, Cardiac Output, Ventilation
- Trial name
- NCT01168557
- Testing
- EIT (Electrical Impedance Tomography)
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- RWTH Aachen University
Acute Pain, Respiration
Clonidine-Remifentanil. Effect of the Combination on Acute Pain and Respiration in Healthy Volunteers
The hypothesis is that systemic remifentanil and Clonidine act in a synergistic manner to relief acute main in an experimental human pain model.
- Conditions
- Acute Pain, Respiration, Sedation
- Trial name
- Remiclon (NCT00730054)
- Testing
- Remifentanil+clonidine
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Respiration, Artificial, Hemorrhage
Impact of Heparin on the Need for Mechanical Ventilation in Neonates
This study is designed to test an incidental finding of a previous trial in which post hoc analysis showed that the rate of intensive care newborns requiring mechanical ventilation was lower in the group receiving heparin with…
- Trial name
- NCT00196469
- Testing
- heparin
- Where
- Germany
- Volunteers
- 270 people
- Sponsor
- University Medicine Greifswald
Pulmonary Disease, Chronic Obstructive
Single Doses GSK159797 On Patient Safety And Lung Function In Patients With Mild To Moderate Asthma
This study was designed to test safety aspects and effects on lung function of a new dry powder version of GSK159797 for asthmatic subjects to inhale.
- Trial name
- NCT00354666
- Testing
- GSK159797
- Volunteers
- 20 people
- Sponsor
- GlaxoSmithKline
Acid Aspiration Syndrome
Detection of Silent Aspiration Events Utilizing pH/Impedance Probes in Hospitalized Patients
Monitoring and quantification of reflux events in high risk critically ill inpatients and lower risk general medical/surgical inpatients, with comparison to relevant clinical variables.
- Trial name
- NCT02720029
- Testing
- pH/impedance monitor
- Sponsor
- Vanderbilt University
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