Clinical trials: Aspiration, Respiratory
Asthmatic
Effects of Costovertebral Joint Mobilization on Respiratory Function in Asthmatic Patients
The aim of this randomized controlled trial is to determine the effectiveness of costovertebral joint mobilization on lung function in asthmatics.
- Trial name
- NCT06133985
- Testing
- Costovertebral mobilizations + Conventional PT, Conventional treatment
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Low Back Pain
Low Back Pain and Breathing Pattern Dysfunction
The goal of this study is to identify if there is a significant prevalence of abnormal respiratory patterns in a sample of patients with low back pain (LBP), and if the presence of abnormal respiratory patterns are predictive of…
- Trial name
- LBP&BPD (NCT02429752)
- Testing
- Inspiratory muscle training
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
Aspiration Pneumonia, Tracheostomy
Continuous Enteral Feeding Until Tracheostomy and Aspiration Risk
This prospective observational study evaluates whether continuing enteral feeding until tracheostomy affects aspiration pneumonia risk and early clinical outcomes in mechanically ventilated intensive care unit patients undergoing…
- Conditions
- Aspiration Pneumonia, Tracheostomy, Mechanical Ventilation
- Trial name
- NCT07508293
- Testing
- Continuous enteral feeding, Fasting
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Iatrogenic Pneumothorax, Vacuum Bottle Assisted Needle Aspiration
Pneumothorax Drainage With Vacuum Bottle
The use of vacuum bottle in drainage of pneumothorax was seldom reported. This study aims to investigate the safety of vacuum bottle plus non-tunneled catheter for drainage of iatrogenic pneumothorax.
- Trial name
- NCT03724721
- Testing
- vacuum bottle
- Where
- Taiwan
- Volunteers
- 23 people
- Sponsor
- National Taiwan University Hospital
Congestive Heart Failure
Study for Breathing Interventions in Congestive Heart Failure
Slow breathing may reduce stress. Adults with congestive heart failure have higher stress than the general population. This study will examine if using slow breathing is feasible among adults with heart failure.
- Trial name
- NCT03449121
- Testing
- Slow breathing techniques
- Sponsor
- Vanderbilt University Medical Center
COPD
Investigate the Safety, Tolerability and Pharmacokinetics of CHF6523 in Healthy and in COPD Subjects
This study is designed to investigate the safety, tolerability and pharmacokinetics of inhaled CHF6523 DPI in healthy male subjects first and then in COPD subjects after single or repeated dosesof CHF6523.
- Trial name
- CHF6523 (NCT04032535)
- Testing
- CHF6523
- Where
- United Kingdom
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Aspiration of Subglottic Secretions
Aspiration of Subglottic Secretions Using Hi-Lo Evac Endotracheal Tube: Tube Size and Incidence of Suction Lumen Dysfunction
To evaluate the correlation between endotracheal tube size and incidence of dysfunction of suction lumen of Hi-Lo Evac endotracheal tube in critically ill patients who required mechanical ventilation for more than 48 hours.
- Trial name
- NCT00450476
- Testing
- Hi-Lo Evac Endotracheal Tube
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University Hospital, Alexandroupolis
Lung Cancer, Mediastinal Lymphadenopathy
Capillary Versus Suction Needle Aspiration for Endobronchial Ultrasound (EBUS) Biopsies.
Endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration is a procedure used to obtain tissue samples (biopsies) of lymph nodes near the airways or of lung tumours growing in close proximity to the airways.
- Conditions
- Lung Cancer, Mediastinal Lymphadenopathy, Thoracic Cancer
- Trial name
- CAPSUNN-EBUS (NCT04306614)
- Testing
- Endobronchial Ultrasound guided Transbronchial Fine Needle Aspiration
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- Western University, Canada
Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary
Magnesium for Neonatal Neuroprotection and Mothers
Magnesium is a treatment for mothers to protect brains of babies born early. This study investigates combined effects of magnesium and spinal or epidural anesthesia on mothers having cesareans.
- Conditions
- Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary, Respiratory Depression
- Trial name
- MnMs (NCT01482078)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Disease, Pulmonary
Study to Evaluate the Safety and Pharmacokinetics of Inhaled Ciprofloxacin in Patients With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)
Objectives of the study are to investigate the safety, tolerability and levels of ciprofloxacin in the lung after single and multiple inhalative administration to patients with mild to moderate COPD (stage I-II according to GOLD…
- Trial name
- NCT01052298
- Testing
- Ciprofloxacin (Cipro inhale, BAYQ3939)
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Bayer
Smokers
Effects of Mental Practice and Therapeutic Exercise in Mild Smokers
The goal of this clinical trial is to learn about the effects who would add mental practice based on action observation to a therapeutic exercise program in young mild smokers.
- Trial name
- NCT06123598
- Testing
- Therapeutic exercise program plus action observation training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Ventilator Acquired Pneumonia, Aspiration
Comparison of Two Strategies of Oropharyngeal and Tracheal Suctioning in Mechanically Ventilated Patients
The purpose of this study is to evaluate the impact of an optimized suctioning procedure on the risk of endotracheal microaspiration, measured by tracheal to oropharyngeal ratio of amylase enzymatic activity.
- Trial name
- AMYLASPI (NCT01807884)
- Testing
- Optimized oral care, Routine oral care
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Bordeaux
Airway Obstruction, Sedation Complication
Evaluation of Medical Device for Airway Patency During Sedation (SW01-2022)
The goal of this four-part preclinical [I-II] and clinical [III-IV] trial is to compare, with randomised crossover study design [I-IV], a new medical airway device with standard procedure (biteblock or no device) for upper airway…
- Conditions
- Airway Obstruction, Sedation Complication, Safety Issues, Patient Satisfaction
- Trial name
- NCT05708651
- Testing
- Investigational device [I-IV], Comparator [I-IV]
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Stairway Medical AB
Stroke Patients
Relationship Between Respiratory Muscle Strength, Balance, Trunk Control, Functional Capacity in Stroke Patients
The purpose of this study; To determine the relationship between respiratory muscle strength, balance, trunk control, functional capacity and motor functions in stroke patients and compare them with healthy individuals.
- Trial name
- NCT06259877
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Cerebral Palsy, Respiratory Function Tests
Respiratory Function, Respiratory Muscle Strength, and Hand Function in Hemiparetic Cerebral Palsy
The goal of this observational study is to learn how respiratory function and respiratory muscle strength are related to hand use in children and teenagers with hemiparetic cerebral palsy (CP) aged 6 to 18 years.
- Conditions
- Cerebral Palsy, Respiratory Function Tests, Fine Motor Skills
- Trial name
- NCT07394439
- Volunteers
- 37 people
- Sponsor
- Halic University
Surgery, Anesthesia
Evaluation of a Novel Portable Capnograph (MARIE) in Adult Postoperative Patients
Postoperative respiratory complications are common and sometimes hard to detect early. Desaturation is a late sign of reduced minute ventilation, especially if the patient is on supplemental oxygen, and measurement of arterial or…
- Conditions
- Surgery, Anesthesia, Postoperative Care, Respiration Rate Detection
- Trial name
- NOVOCAP-Postop (NCT07178236)
- Testing
- MARIE
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Malin Jonsson Fagerlund
COVID-19 Acute Respiratory Distress Syndrome, Respiration, Artificial
Flow-controlled Ventilation (FCV) in Moderate Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19
Flow controlled ventilation (FCV) is a fairly new mode of mechanical ventilation, consisting of a constant inspiratory and expiratory flow. Inspiration is thus comparable to volume controlled ventilation (VCV).
- Trial name
- VICAR (NCT04894214)
- Testing
- Arterial blood gas (ABG), Recording of hemodynamic monitoring, Recording of respiratory monitoring
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- University Hospital, Antwerp
Neonatal Respiratory Distress
Aerosolized Infasurf Treatment Protocol: Aerosolized Infasurf for Spontaneously Breathing Patients With Early RDS (AERO-03)
Surfactant replacement therapy can be life-saving for newborn infants born with symptomatic lung surfactant deficiency causing Respiratory Distress Syndrome (RDS).
- Trial name
- NCT03582930
- Testing
- Infasurf Aero
- Where
- 5 sites in United States
- Sponsor
- ONY
Respiratory Failure
Extubation Readiness and Neuroventilatory Efficiency After Acute Respiratory Failure
The aim of this study was to compare the indices of rapid shallow breathing, neuromechanical efficiency (NME), and neuroventilatory efficiency (NVE) between patients being successfully extubated and those who failed weaning.
- Trial name
- NCT01065428
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Southeast University, China
Respiration, Artificial, Acute Hypoxemic Respiratory Failure
Adherence to Low Tidal Volume in the Transition to Spontaneous Ventilation in Patients With Acute Respiratory Failure
The goal of this observational study is to estimate the prevalence of the use of protective ventilation with low tidal volume ventilation in the transition of spontaneous ventilation modes in patients with hypoxemic acute…
- Conditions
- Respiration, Artificial, Acute Hypoxemic Respiratory Failure, Respiratory Insufficiency
- Trial name
- SPIRAL (NCT06042036)
- Testing
- Spontaneous mode of mechanical ventilation
- Where
- 10 sites in Argentina, Bolivia and 8 more
- Volunteers
- 431 people
- Sponsor
- University of Sao Paulo General Hospital
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