Clinical trials: Aspirin Resistance
Diabetes Mellitus Type 2, Coronary Artery Diseases
Comparison of Effects of Buffered and Enteric-coated Forms of Aspirin on Platelet Aggregation in Patients With Diabetes Mellitus and Chronic Coronary Syndrome
Patients with diabetes mellitus are characterized by "hyperreactive" platelets and a reduced response to ASA compared to individuals without diabetes.
- Conditions
- Diabetes Mellitus Type 2, Coronary Artery Diseases, Aspirin Resistance
- Trial name
- CASCADE (NCT06716255)
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Nizhpharm
Aspirin Resistance
Aspirin Resistance and Prognosis of Patients With Critical Limb Ischaemia
Acetylsalicylic acid (Aspirin, ASA) is the most widely prescribed drug used in primary and secondary prevention of cardiovascular disease.
- Trial name
- Aspirine (NCT01104441)
- Where
- 2 sites in France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Limoges
Aspirin Resistance
The Efficacy of Aspirin in the Postoperative Period in Vascular Surgery
The purpose of this study is to determine the incidence of aspirin resistance in the population of vascular surgery patients; and to evaluate the changes in the efficacy of aspirin in the first five postoperative days.
- Trial name
- NCT01432652
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Lausanne Hospitals
Aspirin Resistance
Aspirin Resistance Reversibility in Diabetic Patients
The aim of the study is assessing the prevalence of aspirin resistance in a cohort of diabetic patients. Those found resistant has been undergone pharmacological tests using different drug formulations to investigate the…
- Trial name
- ARRDM (NCT01935193)
- Testing
- lysine acetylsalicylate
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Coronary Artery Disease, Aspirin Resistance
Dual Antiplatelet Therapy in Patients With Aspirin Resistance Following Coronary Artery Bypass Grafting
Reactive platelet hyperactivity following coronary artery bypass grafting (CABG) might lead to thrombotic complications and major ischemic cardiac events.
- Trial name
- NCT01159639
- Testing
- Clopidogrel
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- University of Zagreb
Aspirin Resistance
Prevalence and Profile of Aspirin Resistance in Hemodialysis Patients
Dialysis patient could be more aspirin resistant than the general population based on data from chronic kidney disease patients
- Trial name
- NCT00792272
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Aspirin Resistance, Hypercholesterolemia
The Effect of Serum LDL Lowering on Aspirin Resistance
Aspirin resistance is the persistent platelet activation, demonstrated by platelet function tests (1). The hypothesis is that:LDL lowering by statin in patients with aspirin resistance can improve the effect of aspirin due to the…
- Trial name
- NCT00466154
- Testing
- Aspirin
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Carotid Artery Stenosis, Ischemic Stroke
Platelet Reactivity and MES During CEA
The purpose of this study is to analyze the association between aspirin efficacy and general platelet reactivity in relation to microembolic signals (MES) during carotid endarterectomy (CEA).
- Conditions
- Carotid Artery Stenosis, Ischemic Stroke, Myocardial Infarction, Aspirin Resistance
- Trial name
- NCT01547039
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- UMC Utrecht
Aspirin Resistance, Pharmacological Aspirin Non-responsiveness
Mechanism Based Resistance to Aspirin
The purpose of this research is to study why some people do not respond to the benefits of aspirin therapy. The benefit of aspirin is cardioprotection, or decreasing the risk of heart attack and/or stroke.
- Trial name
- NCT00948987
- Testing
- Aspirin
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania