Clinical trials: Assessment
Healthy Volunteers, Diabetes Mellitus, Type 1
Evaluation of 18 F-FP-DTBZ Pancreatic PET Scanning as a Tool to Measure Beta Cell Mass
Type 1 diabetes mellitus (T1DM) develops when there is impaired insulin production due to loss of insulin producing cells (beta cells).
- Trial name
- NCT02236754
- Testing
- 18 F-FP-DTBZ, PET Scanning
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Multi Drug Resistant Tuberculosis, HIV Infections
An Adaptive Randomized Controlled Trial
This is a prospective, adaptive, randomized controlled trial comparing the effectiveness of 4 intervention arms on a combined endpoint in adults with confirmed MDR-TB HIV initiating Bedaquiline-containing MDR-TB treatment…
- Trial name
- ADAP-TIV (NCT05633056)
- Testing
- Adherence support intevention
- Where
- South Africa
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Columbia University
Physical Activity
Increasing Physical Activity in Latino Men
The purpose of this study is to determine the feasibility and preliminary efficacy of a web and text-messaged based intervention designed to increase physical activity among Latino men in Rhode Island.
- Trial name
- NCT03196570
- Testing
- Physical Activity Intervention, Wellness Contact Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Low Vision Aids
Shilangqing Smart Reading Aid for Improving Reading Ability in Children With Low Vision
This clinical trial aims to assess the efficacy and safety of the Shilangqing Smart Reading Aid, a head-mounted device integrating XR and AI technologies, in improving reading performance and quality of life among children with…
- Trial name
- NCT07336069
- Testing
- "Langshiqng" visual aid device
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Activity, Motor, Biomarkers
Comparison of the Effects of Aerobic-Anaerobic Exercises on Hormonal and Immune Biomarkers
This study aims to compare the effects of aerobic and anaerobic exercise on hormonal, immunological, and metabolic biomarkers in young individuals using blood and saliva samples.
- Conditions
- Activity, Motor, Biomarkers, Exercise, Immunity
- Trial name
- Biomarkers (NCT07092969)
- Testing
- Treadmill Exercise, Bicycle Exercise
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sakarya Applied Sciences University
HIV Infections, Sleep Disorder
Assessment of Sleep Disordersin People Living With HIV in the Era of New Antiretroviral Therapies in North of France
People living with HIV (PLHIV) appear to present with sleep-related complaints more frequently than the general population, with a prevalence of 50-70%. The latest French multi-center epidemiological data are dated.
- Trial name
- SANDMAN (NCT06441383)
- Testing
- Pittsburgh Sleep Quality Index
- Where
- France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Tourcoing Hospital
Carpal Tunnel, Carpal Tunnel Syndrome
Evaluation of Carpal Tunnel Syndrome in Pregnancy
Carpal tunnel syndrome (CTS) is a condition that happens when the median nerve in the wrist gets compressed, causing pain, numbness, and tingling in the hand and fingers.
- Trial name
- NCT05839769
- Testing
- Evaluation of median nerve with ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Cognitive Decline, Executive Dysfunction
Fitness on White Matter and Cognition in Aging
Cardiorespiratory fitness (CRF) is associated with decreased risk for mild cognitive impairment (MCI) and dementia. CRF is linked with more conserved gray and white matter (WM) volume, improved WM microstructural integrity, and…
- Conditions
- Cognitive Decline, Executive Dysfunction, Cardiovascular Risk Factor
- Trial name
- NCT03775941
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- Suffolk University
Healthy Volunteers
Lung Deposition Via Different Inhalation Devices
The purpose of this study is to assess the deposition of budesonide to the lung after inhalation with 5 different devices and to relate the findings to in vitro properties of inhaled budesonide.
- Trial name
- NCT00975754
- Testing
- Pulmicort pMDI HFA, Budesonide pMDI HFA, Pulmicort Repulses
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
A Relative Bioavailability and Bioequivalence Study of Varegacestat in Healthy Participants
This is an open-label, randomized, crossover study to evaluate the relative bioavailability (rBA) and bioequivalence (BE) of a test capsule formulation of varegacestat compared to reference capsules formulation under fasting…
- Trial name
- NCT07610005
- Testing
- Varegacestat Reference Formulation, Varegacestat Test Formulation A, Varegacestat Test Formulation B
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Immunome, Inc.
Metastatic Pancreatic Cancer
Nab-paclitaxel and Gemcitabine in Metastatic Pancreatic Cancer
This is a single arm, open-label Phase II clinical trial to Evaluate the Efficacy and Safety of the Combination of Nab-paclitaxel and Gemcitabine in Treating Patients with metastatic pancreatic cancer.
- Trial name
- NCT03929094
- Testing
- Paclitaxel for Injection（Albumin Bound）, Gemcitabine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fudan University
Healthy
Camel Milk Impact on Aerobic Exercise Recovery, Induced Inflammation, and Physical Performance
Study title Camel Milk Impact on Aerobic Exercise Recovery, Induced Inflammation, and Physical Performance Investigator Dr. Mo'ath Bataineh Department of Nutrition and Health College of Medicine \& Health Sciences United Arab…
- Trial name
- NCT07491705
- Testing
- Control, Camel Milk, Cow Milk
- Where
- United Arab Emirates
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Evaluate the Immediate Loading Implants in All on 4 Cases Using Conversion Denture and OT Bridge System
Splinted and Unsplinted OT Bridge Systems in Screw Retained Implant Restoration
Evaluation of Bone level changes around dental implants in All on 4 cases with immediate loading using conversion denture and OT Bridge system either splinted or not
- Trial name
- OTBS (NCT05031156)
- Testing
- Splinting of OT Bridge system
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pediatric Post Extubation Dysphagia
The Use of PEDI_ EAT 10 Score Versus Nurse Performed Screening in the Assessment of Post Extubation Dysphagia
Invasive mechanical ventilation is one of the most common interventions in critically ill patients, and is invariably characteristic, if not defining, of ICU therapeutic regimen Much attention has been paid to complications…
- Trial name
- NCT05828537
- Testing
- endotracheal tube
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Old Age, Frailty
Effects of Physical Exercise on Frailty, Mental and Physical Health of Older Adults in Rural Areas.
Global aging is a significant challenge, both economically and in terms of public health. One of the main challenges is to maintain the health and functionality of older adults.
- Trial name
- Rural-Frail (NCT06556537)
- Testing
- Face-to-face and video-assisted training
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Blood Loss, Surgical, Postoperative Hemorrhage
Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.
The goal of this clinical trial is to learn whether the Hemorai Vysio wearable device can be used safely and feasibly to track relative changes over time in tissue oxygen, hemoglobin-related signals, blood flow, and oxygen use…
- Trial name
- VYSIO-FEASIBIL (NCT07826637)
- Testing
- Wearable optical hemodynamic monitoring device
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hemorai Inc
Evaluate the Safety and Efficacy of Apixaban
A Multi-center Study of Apixaban(APPROACH)
The aim of the study is to enroll approximately 200 cases from 10 research centers nationwide, completed left atrial appendage occlusion (LAAO) successfully, and give apixaban (5 mg bid) postoperatively.
- Trial name
- NCT04550637
- Testing
- Oral apixaban
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Sunscreening Agents
Evaluation of the Irritation Potential of Sunscreen Products in Human Eyes
Evaluation of the human eye irritation potential of a test sunscreen formulation.
- Trial name
- NCT02854137
- Testing
- BAY987521, Control
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Bayer
Polycythemia Vera
Standardized Documentation and Assessments for Polycythemia Vera: A Quality Improvement Initiative
The purpose of this quality improvement initiative is to explore whether an electronic medical records-based templated progress note for polycythemia vera (PV) in addition to a standard-of-care pharmacist-collaborative…
- Trial name
- STANDARDIZE-PV (NCT07734272)
- Testing
- Standardized progress note
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Postural Control, Athletic Performance
Core Strength Training, Anthropometry, and Postural Control in Youth Optimist Sailors
Optimist dinghy sailing is a highly demanding youth watersport characterized by prolonged, high-intensity isometric hiking postures and rapid dynamic weight shifts required to preserve boat trim, balance, and sail power output.
- Conditions
- Postural Control, Athletic Performance, Physical Fitness, Core Stability
- Trial name
- NCT07802782
- Testing
- Core Strength Training (CST), Technical Sailing Training (TST)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Foggia
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