Clinical trials: Assessment, open to volunteers
Stroke, Stroke Assessment
Non-Invasive Deep Brain Stimulation for Upper Limb Recovery After Stroke (NIMBUS)
NIMBUS is a clinical study evaluating a new, non-invasive brain stimulation treatment to improve arm and hand function in people with long-term effects of stroke.
- Trial name
- NIMBUS (NCT07792811)
- Testing
- Non-invasive transcranial Temporal Interference Stimulation (iTBS-tTIS Striatum), Concurrent Intensive Motor Rehabilitation
- Where
- Switzerland
- Volunteers
- 84 people
- Sponsor
- Friedhelm Hummel
To Assess the Feasibility, Visualization Capability, and Optimal Dosing of ICG Fluorescence Imaging for Intraoperative Assessment of Knee Tissue Perfusion
ICG Fluorescence in Knee Arthroscopy Study
The purpose of this study is to first evaluate whether ICG fluorescence angiography can be used to evaluate blood flow of the anterior cruciate ligament (ACL), tendons, and knee structures during an arthroscopic surgery.
- Trial name
- NCT07793266
- Testing
- Intravenous administration of indocyanine green (SPY Agent Green) 2 mL of SPY Agent Green (5.0 mg dose), Intravenous administration of indocyanine green (SPY Agent Green) 3 mL of SPY Agent Green (7.5 mg dose), Intravenous administration of indocyanine green (SPY Agent Green) 4 mL of SPY Agent Green (10 mg dose)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Henry Ford Health System
Ultrasound-guided Fluid Management, Volume Responsiveness
Perceptions and Ultrasound Literacy for Sound Volume Management
The aim of this study is to assess the knowledge, attitudes, and practices of ICU physicians in Switzerland regarding the use of ultrasound for fluid management and evaluation of venous congestion.
- Conditions
- Ultrasound-guided Fluid Management, Volume Responsiveness, Venous Congestion Assessment, ICU Physician Practices
- Trial name
- PULSE (NCT07237347)
- Testing
- Quastionnaire
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Basel, Switzerland
Airway Management Assessment, Awake Endotracheal Intubation
Comparison of Awake Tracheal Intubation Methods
The aim of this study was to compare three different awake tracheal intubation technique -fiberoptic bronchoscopy (ATI:FB), videolaryngoscopy (ATI:VL), and fiberoptic bronchoscopy via a supraglottic airway device (ATI:SAD)- in…
- Conditions
- Airway Management Assessment, Awake Endotracheal Intubation, Awake Fiberoptic Nasal Intubation, Videolaryngoscopy
- Trial name
- ATI (NCT07484841)
- Testing
- Awake tracheal intubation viaFiberoptic Bronchoscopy (ATI:FOB), Awake tracheal Intubation via videolaryngoscopy (ATI:VL), awake tracheal intubation via aintree catheter loaded FOB through supraglottic airway device (ATI:SAD)
- Where
- Turkey (Türkiye)
- Volunteers
- 201 people
- Sponsor
- Kocaeli City Hospital
Lung Cancer (NSCLC), Geriatric Assessment
Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy
National guidelines recommend that older adults with cancer undergo a special health assessment before starting cancer treatment.
- Conditions
- Lung Cancer (NSCLC), Geriatric Assessment, Stereotactic Body Radiation Therapy (SBRT)
- Trial name
- Lung-GAP (NCT06987890)
- Testing
- Practical Geriatric Assessment
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Brigham and Women's Hospital
Consciousness Assessment
New Consciousness Indicators (NCI)
The assessment of the diagnosis and prognosis of patients with disorders of consciousness (DoC) represents a major clinical and ethical challenge, as it may influence therapeutic decision-making.
- Trial name
- NCI (NCT07786298)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liege
Cognitive Risk Assessment
A Cognitive Risk Calculator and Screening Tool for Primary Care Settings
This mixed-methods pragmatic trial will use a stepped wedge cluster randomized design to implement a cognitive risk-calculator and automated cognitive screening tool (BACH) in eight internal medicine clinics in the Cleveland…
- Trial name
- NCT06506877
- Testing
- Implementation of Cognitive Risk Calculator (RC) and Brief Assessment of Cognitive Health (BACH)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Cardiovascular Risk Assessment, Rheumatoid Arthritis (RA)
Twenty-four Hour Movement Behaviors and Atherosclerotic Risk
This observational study aims to investigate how 24-hour movement behaviors are associated with atherosclerotic risk in adults with rheumatoid arthritis. These behaviors include physical activity, sedentary behavior, and sleep.
- Conditions
- Cardiovascular Risk Assessment, Rheumatoid Arthritis (RA), 24-Hour Movement Guidelines
- Trial name
- PASSARO (NCT07774507)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- São Paulo State University
Clinical Competence, Ultrasonography
Remote Guidance for eFAST Training Using a Head-Mounted Device
This study looks at the best way to remotely teach and guide doctors-in-training to perform a bedside ultrasound exam called eFAST (extended Focused Assessment with Sonography for Trauma), which is used to quickly check injured…
- Conditions
- Clinical Competence, Ultrasonography, Medical Education, Point-of-care Ultrasound (POCUS)
- Trial name
- Remote-eFAST (NCT07686497)
- Testing
- Standardized instructional eFAST video, Real-time audio remote expert guidance (Microsoft Teams), Head-mounted-device remote expert guidance (Arc 3, RealWear)
- Where
- Switzerland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Philipp Fürnstahl
Arthroplasty, Replacement, Knee, Nerve Block Assessment
Ultrasonographic Predictors of Adductor Canal Block Effectiveness in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with substantial postoperative pain and opioid requirements, making effective multimodal analgesia essential for early mobilization, functional recovery, and reduction of opioid-related…
- Conditions
- Arthroplasty, Replacement, Knee, Nerve Block Assessment, Pain, Postoperative Arthroscopy
- Trial name
- NCT07730216
- Testing
- Adductor Canal Block (ACB) Only
- Where
- Turkey (Türkiye)
- Volunteers
- 623 people
- Sponsor
- Konya City Hospital
Motor Coordination Assessment
Turkish Adaptation and Validation of the Adolescents and Adults Coordination Questionnaire
Coordination is an essential component of motor control that supports the performance of daily activities and physical function.
- Trial name
- NCT07754487
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gulser CINBAZ
Acute Kidney Injury After Adult Cardiac Surgery, Gastrointestinal Microbiome
Development and Validation of a Risk Prediction Model for Cardiac Surgery-associated Acute Kidney Injury Based on the Gut-Kidney Axis, Incorporating Gut Microbiota and Their Metabolites
This is a single-center prospective observational cohort study enrolling adult patients scheduled for cardiac surgery. Multi-timepoint clinical indicators, stool samples for gut microbiota and metabolomics profiling and artery…
- Conditions
- Acute Kidney Injury After Adult Cardiac Surgery, Gastrointestinal Microbiome, Metabolome, Risk Assessment
- Trial name
- NCT07738796
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Peking Union Medical College Hospital
Menopause, Perimenopause
Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition
The goal of this clinical trial is to learn whether it is feasible to conduct a larger study comparing transdermal menopausal hormone therapy (MHT) versus no hormone therapy in menopausal women with vasomotor symptoms (hot…
- Conditions
- Menopause, Perimenopause, Vasomotor Symptoms, Cardiovascular Disease Risk Factor
- Trial name
- HERBRAVEHEART (NCT07732452)
- Testing
- Transdermal estradiol, Standard of care - non hormonal
- Volunteers
- 100 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Vestibular Dysfunction, Dizziness
Vestibular Balance-Cognition Dual-Task Digital System: Development of a Smart Rehabilitation Platform for the Elderly and Prediction of Balance Function Risks
This study is being done to better understand how vestibular problems and thinking abilities (such as attention and mental flexibility) are related in older adults, and how doing a balance task and a thinking task at the same…
- Conditions
- Vestibular Dysfunction, Dizziness, Falls (Accidents) in Old Age, Balance Assessment
- Trial name
- NCT07735078
- Testing
- Instrumented balance and gait assessment using wearable inertial sensors, Questionnaires and paper-based cognitive tests
- Where
- Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Geriatric Assessment
Frailty Syndrome and Its Associated Factors Among Elderly Patients
This is a cross-sectional analytical study conducted among elderly patients attending Assiut university hospital. 2.4. 2- Study Setting:The study will be conducted in Assiut University hospital, including outpatients and…
- Trial name
- Frailty (NCT07727811)
- Volunteers
- 175 people
- Sponsor
- Assiut University
Cardiac Arrest (CA), Return of Spontaneous Circulation
Pulse Detection in Cardiac Arrest Patients Using a Doppler Ultrasound Patch on the Carotid Artery
The purpose of this study is to find out if a Doppler ultrasound patch placed on the neck can accurately and quickly detect when a cardiac arrest patient's heart starts beating again (return of spontaneous circulation, or ROSC)…
- Conditions
- Cardiac Arrest (CA), Return of Spontaneous Circulation, CPR Quality Assessment
- Trial name
- NCT07729228
- Testing
- Ultrasound doppler perfusion monitoring
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Heartstream US LLC
Vagus Nerve Stimulation, Stroke
Vagal Nerve Stimulation To Enhance Cognition and Learning
The purpose of this study is to find out whether pairing vagus nerve stimulation (VNS) with cognitive training can improve memory and language learning in people who have previously used VNS therapy for movement rehabilitation…
- Conditions
- Vagus Nerve Stimulation, Stroke, Cognitive Assessment, Language Acquisition
- Trial name
- NCT07719387
- Testing
- VNS for Cognition
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stony Brook University
Assessment of ONSD, ODE and the Crescent Sign Using POCUS
Diagnostic Accuracy of ONSD, ODE, and the Crescent Sign
Our aim was to determine the diagnostic accuracy of the ONSD, ODE, and crescent sign, as detected by POCUS, in identifying the clinical and radiological features of increased intracranial pressure.
- Trial name
- NCT07719842
- Testing
- Ultrasound assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
IBD, Crohn Disease (CD)
Assessment and Educational Intervention to Reduce Ultra-processed Food Consumption in Pediatric Patients With IBD
This study explores whether simple nutrition education can help children and teens with inflammatory bowel disease (IBD) eat fewer ultra-processed foods (UPFs).
- Conditions
- IBD, Crohn Disease (CD), Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD)
- Trial name
- NCT07224113
- Testing
- Handout-Only Intervention, Handout + Video Intervention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center