Clinical trials: Assessment Time
Leishmaniasis
Safety, Tolerability and Pharmacokinetics (PK) Investigation of GSK3494245 in Healthy Participants
This study is the first to test GSK3494245 in humans, to evaluate its safety, tolerability, and pharmacokinetics (PK) after a single dose.
- Trial name
- NCT04504435
- Testing
- GSK3494245
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Volunteers
A Brain Imaging Study With Positron Emission Tomography and the Radiotracer [11C]UCB-J to Estimate How Fast Brivaracetam and Levetiracetam Enter the Brain in Healthy Volunteers
This study will estimate how fast two antiepileptic drugs (Levetiracetam and Brivaracetam) enter the human brain. Brain imaging will be used to measure how quickly the radioactive probe [11C]UCB-J exits the brain when…
- Trial name
- NCT02602860
- Testing
- [11C]UCB-J, Brivaracetam, Levetiracetam
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- UCB Pharma
Fatigue Symptom, Fatigue Intensity
Monitoring Fatigue In Daily Life In Adults With Cerebral Palsy or Acquired Brain Injury
The goal of this observational study is to learn about levels and patterns of fatigue in adults with cerebral palsy (CP) and acquired brain injury (ABI) in daily life.
- Conditions
- Fatigue Symptom, Fatigue Intensity, Cerebral Palsy (CP), Acquired Brain Injury Including Stroke
- Trial name
- NCT07135791
- Testing
- Real-time monitoring
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Parenting Practices, Co-parenting Practices
The Good Start Matters - Parenting Program
Early childhood is an important period where the family can support the development and maintenance of healthy eating and active behaviors to prevent or reduce childhood obesity.
- Conditions
- Parenting Practices, Co-parenting Practices, Child Eating and Dietary Behaviors, Child Physical Activity/active Play/outdoor Play
- Trial name
- NCT05802160
- Testing
- Good Start Matters - Parenting intervention
- Where
- Canada
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Health Behavior
Implementation of Standing Desks at School
Since sedentary time is related to various health outcomes and is already highly prevalent in childhood and adolescence, effective strategies are needed to tackle this health problem.
- Trial name
- NCT03163004
- Testing
- Implementation of standing desks
- Where
- Belgium
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- University Ghent
Sedentary Behavior
Interrupting Sitting Time During Postprandial State
The literature has shown that interrupting sitting time with frequent physical activities (e.g., cycling on a stationary bike for 3 minutes every 30 minutes of sitting) is effective for decreasing blood sugar levels.
- Trial name
- NCT04590729
- Testing
- 3-min Exercise Per 30 Min, 3-min Exercise Per 15 Min
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Franklin Pierce University
Heart Failure, Diastolic
Exercise Pulmonary Transit Time
The study seeks to measure pulmonary transit time via contrast-echocardiography before and after exercise.
- Trial name
- NCT04336995
- Testing
- contrast echocardiography
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Arthritis, Rheumatoid
First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699
This FTIH study, intends to identify the doses of GSK3358699, which are well tolerated by the subjects whilst delivering a robust pharmacodynamic (PD) response.
- Trial name
- NCT03426995
- Testing
- GSK3358699, GM-CSF, LPS
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity, Childhood, Physical Activity
Fit 5 Kids Screen Time Reduction Curriculum for Latino Preschoolers
Childhood obesity and metabolic risk are at record high levels in the US, and Latino children are at very high risk. This project will test an intervention called Fit 5 Kids, designed for Latino preschoolers to decrease their…
- Conditions
- Obesity, Childhood, Physical Activity, Nutrition
- Trial name
- Fit5Kids (NCT03575884)
- Testing
- Screen Time Reduction Curriculum
- Where
- 3 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Anticoagulation Reversal
Study of PER977 Administered to Subjects With Steady State Edoxaban Dosing and Re-anticoagulation With Edoxaban
This study will evaluate the establishment of anticoagulation ("re-anticoagulation") of subjects with edoxaban following reversal by PER977 and will identify a dose regimen of PER977 that reverses the effects of edoxaban for up…
- Trial name
- NCT02207257
- Testing
- PER977, Edoxaban
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.
Kidney Stones
Donors With Nephrolithiasis at the Time of Transplant Evaluation (DONATE). Long Term Follow-up.
We believe that kidney donors with kidney stones accepted for a donation do not have an increased risk of loss of kidney function and will not be at increased risk of symptomatic kidney stone events compared to donors without a…
- Trial name
- DONATE (NCT05519150)
- Testing
- low dose radiation abdomen/pelvis CT scan (stone protocol), Blood draw, 24 hour urine collection
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Indiana University
Postspinal Hypotension, Pregnant Women Undergoing Cesarean Delivery
Carotid Flow Measurements in Pregnant Women
The goal of this observational study is to reveal the relation between carotid flow changes and post-spinal hypotension in pregnant women between the ages of 20-40.
- Trial name
- NCT06813989
- Testing
- carotid ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Pulmonary Disease, Chronic Obstructive
Evaluation of COPD (Chronic Obstructive Pulmonary Disease) to Longitudinally Identify Predictive Surrogate Endpoints
This is a 3 year longitudinal study to identify novel endpoints and compare these with standard measures such as forced expiratory volume in 1 second (FEV1) for their ability to measure and predict COPD (Chronic Obstructive…
- Trial name
- ECLIPSE (NCT00292552)
- Testing
- Novel endpoint determination
- Where
- 44 sites in United States, Bulgaria and 10 more
- Volunteers
- 2,747 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Workflow, Time
Performance of Acquisition Automation of Cardiac MRI
For this study, cardiac MRI examinations performed will be prospectively included and realized either fully automatically or by a specialized radiology technician.
- Trial name
- NCT06012890
- Testing
- Automation of cardiac MRI acquisition
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Circadian Dysregulation
Efficacy of Ramelteon on Insomnia Symptoms Associated With Jet Lag in Healthy Adult Volunteers
The purpose of this study to determine the degree to which ramelteon, once daily (QD), can reduce the insomnia symptoms associated with rapid, eastward travel across 5 time zones.
- Trial name
- NCT00492011
- Testing
- Ramelteon
- Where
- 4 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy
This Study Will Assess the Safety and Tolerability of AZD8418 After Single Increasing Oral Doses
The main purpose of this study is to assess the safety and tolerability of AZD8418 after single increasing oral doses. Another purpose of this study is to evaluate the pharmacokinetics (also called PK - how the study drug enters…
- Trial name
- NCT01027234
- Testing
- AZD8418
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Normal Pregnancy
Determination of Reference Values for Diluted Russell's Viper Venom Time (dRVVT) Specific to Pregnant Women (GRAPL)
Pregnancy is associated with significant changes in several aspects of haemostasis, especially an imbalance between procoagulant and anticoagulant factors.
- Trial name
- GRAPL (NCT06133621)
- Testing
- dosage dRVVT
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Tobacco Use Disorder, Tobacco Dependence
Equitable Smoking Relapse Prevention
The goal of this clinical trial is to test a GPS (Global Positioning System)-enabled smartphone app (QuitBuddy) in current smokers.
- Trial name
- NCT05625685
- Testing
- Quitbuddy, Control, SDoH Augmentation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bryan W. Heckman
Healthy
Investigation Of Absorption And Pharmacokinetics Of A Single Dose Of Controlled Release Pregabalin Tablet Administered Fasted At Bedtime Or Immediately Following A 400-500 or 600-750 Calorie Evening Meal As Compared To Single Dose Of Immediate Release Pregabalin Capsule In Healthy Volunteers
The purpose of this study is to 1) evaluate the extent of absorption of a single dose of a pregabalin controlled release (CR) tablet administered a) fasted at bedtime, b) immediately following a 400 to 500 calorie evening meal…
- Trial name
- NCT01291524
- Testing
- Pregabalin controlled release, 330 mg, 400 to 500 calorie, Pregabalin controlled release, 330 mg, 600- 750 calorie, Pregabalin controlled release, 330 mg, bedtime
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Schizophrenia
A Study Of The Safety, Tolerability And Pharmacokinetics Of Single Doses Of PF-05180999 In Healthy Adults
The purpose of this study is to determine the safety, tolerability, and pharmacokinetics of 14 days of treatment with PF-05180999 in healthy subjects.
- Trial name
- NCT01429740
- Testing
- PF-05180999
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Pfizer