Clinical trials: Assessment Time
Asthma
Study to Evaluate the Mastery of Inhaler Technique for Budesonide Formoterol (BF) SPIROMAX® as Compared to SYMBICORT® TURBOHALER® as Treatment for Adult Participants With Asthma
This study is conducted to assess whether training participants on proper use of BF SPIROMAX and Symbicort TURBOHALER will improve their device-handling technique and potentially improve their treatment outcome, that is, better…
- Trial name
- ELIOT (NCT02062463)
- Testing
- Budesonide and formoterol fumarate dehydrate (BF) SPIROMAX, SYMBICORT TURBOHALER budesonide and formoterol fumarate
- Where
- 74 sites in United Kingdom
- Volunteers
- 485 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Metastatic Renal Cell Carcinoma
A Retrospective Real World Analysis Of Sutent In Patients With Metastatic Renal Cell Carcinoma In Community And Academic Centers To Assess The Impact Of Dose Variation On Duration Of Response And Overall Survival
This is a retrospective, non-interventional study which looks at the cohort of Renal Cell Carcinoma patients in a real life clinical setting and analyses into factors why these patients have been surviving for as long as 3-5…
- Trial name
- NCT01917214
- Testing
- Sutent: Observational Study
- Volunteers
- 212 people
- Sponsor
- Pfizer
HIV Infections, HSV-2 Genital Herpes
Retention and Duration of Activity of SPL7013 (VivaGel®) After Vaginal Dosing.
To assess the retention and anti-viral activity (human immunodeficiency virus (HIV) and herpes simplex virus 2 (genital herpes, HSV-2) of SPL7013 in cervicovaginal samples taken up to 24 hours after administration of 3% SPL7013…
- Trial name
- NCT00740584
- Testing
- 3% SPL7013 Gel (VivaGel)
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Starpharma Pty Ltd
Gastro-Intestinal Disorder
Evaluation of the Impact of a Forward Viewing Scope at Time of ERCP
This study will be a prospective, tandem-designed study to determine the proportion of clinically significant missed lesions when using a side- or oblique-viewing endoscope as compared to the standard forward-viewing endoscope.
- Trial name
- NCT05627882
- Testing
- Forward viewing endoscope
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pulmonary Arterial Hypertension
FUTURE 3 Study Extension
The objectives of the FUTURE 3 Study Extension are to evaluate the long-term safety, tolerability and efficacy of the pediatric formulation of bosentan two versus three times a day in children with Pulmonary Arterial Hypertension…
- Trial name
- FUTURE 3 Ext (NCT01338415)
- Testing
- Bosentan
- Where
- 36 sites in United States, Australia and 16 more
- Volunteers
- 58 people
- Sponsor
- Actelion
Diabetes Mellitus, Type 1, Hypoglycemia Unawareness
Assessment of the Impact of Real-Time Continuous Glucose Monitoring on People Presenting With Severe Hypoglycaemia
This study aims to assess the impact of real-time continuous glucose monitoring on the frequency, duration, awareness and severity of hypoglycaemia in people with type 1 diabetes and a recent history of severe hypoglycaemia…
- Conditions
- Diabetes Mellitus, Type 1, Hypoglycemia Unawareness, Hypoglycemia
- Trial name
- AIR-CGM (NCT03748433)
- Testing
- Dexcom G6 CGM, Tandem t:slim X2 Insulin Pump
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Imperial College London
Cancer
Definition for the Assessment of Time-to-event Endpoints in CANcer Trials (DATECAN-1)
In randomised phase III cancer clinical trials, the most objectively defined and only validated time-to-event endpoint is overall survival (OS).
- Trial name
- DATECAN-1 (NCT03676010)
- Testing
- Sarcoma and GIST, Breast cancer, Pancreatic cancer
- Where
- 3 sites in France
- Volunteers
- 265 people
- Sponsor
- Institut Bergonié
Capsule Endoscopy
The Second-Generation MCCG for Upper Gastrointestinal Tract.
The aim of this study is to evaluate the clinical application of the second-generation MCCG with higher image resolution and frame rate for upper gastrointestinal tract compared with the first-generation.
- Trial name
- NCT03977935
- Testing
- the second-generation MCCG
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Physical Inactivity
Free Time For Wellness Pilot Effectiveness Trial
Physical inactivity is pervasive and prevalent in the United States, particularly among women of low socioeconomic position, and women with children.
- Trial name
- FT4W (NCT06474715)
- Testing
- Arms
- Where
- 3 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Columbia University
Peripheral Artery Disease (PAD)
Walking Effect of Long Term Ticagrelor in Subjects With PAD Who Have Undergone EVR
To compare the effect of ticagrelor versus aspirin on the change in peak walking time, evaluated on the graded treadmill test, from one to 26 weeks post-revascularization in patients with peripheral artery disease who have…
- Trial name
- TI-PAD EVR (NCT02227368)
- Testing
- Ticagrelor, Comparator
- Where
- 10 sites in United States
- Volunteers
- 40 people
- Sponsor
- AstraZeneca
Complications Associated With Device
Effect of B. Braun Peripheral Advantage Program on Complications, Indwell Time and First Stick Success of PIVC Therapy
Single sequence clinical study designed to evaluate the effectiveness of B. Braun PA on improved clinical outcomes, indwell time and first stick success of PIVC using B. Braun Peripheral Advantage (PA) by Registered Nurses (RNs).
- Trial name
- NCT04048863
- Testing
- B. Braun Peripheral Advantage (PA) Program, Hospital Standard of Care
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- B. Braun Medical Inc.
Hematologic Diseases, Secondary Immune Deficiency
Comparison of Multigam IV (5% vs. 10%) in Patients With an Immunodeficiency Secondary to a Hematological Disorder
The purpose of this observational study is to compare the administration of standard of care Multigam IV 5% and standard of care Multigam IV 10% in order to observe changes in infusion time and infusion related reactions.
- Trial name
- MULTISIM (NCT03250845)
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Hepatitis C Virus (HCV Infection Genotype 1)
Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Co-Administered With Sofosbuvir With and Without Ribavirin in Treatment-Naive HCV Genotype 1-Infected Adults
This open-label study will evaluate the safety and efficacy of co-formulated ombitasvir/paritaprevir/ritonavir and dasabuvir co-administered with sofosbuvir with or without ribavirin administered for either 4 or 6 weeks in…
- Trial name
- NCT02399345
- Testing
- ombitasvir/paritaprevir/ritonavir, dasabuvir, sofosbuvir (SOF), ribavirin (RBV)
- Volunteers
- 10 people
- Sponsor
- AbbVie
Lung Diseases, Interstitial
A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD)
The main objective of the study is to evaluate dose-exposure and safety of nintedanib in children and adolescents with fibrosing Interstitial Lung Disease (ILD).
- Trial name
- InPedILD® (NCT04093024)
- Testing
- Nintedanib
- Where
- 43 sites in United States, Argentina and 19 more
- Volunteers
- 39 people
- Sponsor
- Boehringer Ingelheim
Hepatitis B
Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B Infection
This Phase 1/2a multiple part study is a first time-in-human (FTIH) study designed to evaluate the safety, tolerability, and pharmacokinetics (PK) of single (Part 1) and repeat doses (Part 2) of GSK3965193 in healthy…
- Trial name
- NCT05330455
- Testing
- GSK3965193, Bepirovirsen
- Where
- 14 sites in Canada, France and 4 more
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Bacterial Conjunctivitis
Safety of Besivance™ (Besifloxacin Ophthalmic Suspension) 0.6% Compared to Vehicle
The objective of this study is to evaluate the safety of Besivance (besifloxacin ophthalmic suspension, 0.6%) compared to vehicle.
- Trial name
- NCT01175590
- Testing
- Besivance, Vehicle
- Where
- United States
- Volunteers
- 518 people
- Sponsor
- Bausch & Lomb Incorporated
Conjunctival Staining
Defining the Conjunctival Staining Method: Instillation Volume and Time Course to Assess Staining With Lissamine Green
The purpose of this study is to determine the correct volume of lissamine green to use when assessing conjunctival staining, and to determine the time course needed to evaluate conjunctival staining after lissamine green has been…
- Trial name
- NCT00768898
- Testing
- 2.5/5.0/10.0 µL lissamine green
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Head and Neck Cancer, Stroke
Real-Time Internet Evaluation of Swallowing
The purpose of this study is to determine whether real-time internet evaluations of swallowing, or x-ray swallow studies viewed over closed internet circuit, are a reliable method of evaluating swallowing function.
- Trial name
- NCT00580138
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Major Depressive Disorder
A Study of CX157 (TriRima) for the Treatment of Depression
The purpose of this study is to examine the efficacy of CX157 60 mg administered three times a day (180 mg daily dose) as compared to placebo in subjects with Major Depressive Disorder (MDD).
- Trial name
- CX157-200 (NCT00739908)
- Testing
- CX157 (TriRima)
- Where
- 14 sites in United States
- Volunteers
- 285 people
- Sponsor
- CeNeRx BioPharma Inc.
Pain, Fever
Surveillance Trial to Evaluate a Shortened Infusion Time of Intravenous Ibuprofen
The primary objective of this study is to determine the safety of a single dose of intravenous ibuprofen administered over 5-10 minutes for the treatment of fever or pain in the hospital setting.
- Trial name
- NCT01334944
- Testing
- Intravenous ibuprofen
- Where
- 13 sites in United States
- Volunteers
- 150 people
- Sponsor
- Cumberland Pharmaceuticals