Clinical trials: Assisted Reproductive Technology
Infertility, Infertility (IVF Patients)
Language Matters: Exploring the Impact of Language Concordance on Fertility Treatment Progression
Currently, patients presenting to the Fertility and Reproductive Medicine Center meet with an English-speaking provider and communicate through an interpreter, as none of the physicians speak Spanish.
- Conditions
- Infertility, Infertility (IVF Patients), Infertility Assisted Reproductive Technology, Ovulation Ind
- Trial name
- ImpaLa (NCT06636838)
- Testing
- Spanish-Speaking Provider
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Assisted Reproductive Technology, Female Infertility
A Comparing Study Between SJ04 and Ovidrel® in Healthy Subjects
This is a single-centre, randomised, open-label, single-dose, two-cycle, double-crossover study to compare the pharmacokinetics of SJ04 and Ovidrel® in healthy female subjects.
- Trial name
- NCT06599528
- Testing
- T-R (Test-Reference drug), R-T (Reference-Test drug)
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Suzhou Centergene Pharmaceuticals Co.,Ltd.
Infertility Assisted Reproductive Technology, Infertility, Female
The Effect of Stress Ball Used During Intra Uterine Insemination on Pain, Anxiety, Comfort and Physiological Parameters
This study aimed to determine the effects of holding the patient's hand and using a stress ball during the Intrauterine Insemination procedure on pain, anxiety, comfort, and physiological parameters.
- Trial name
- NCT06759337
- Testing
- Stress Ball Group, Hand-Holding Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- TC Erciyes University
Infertility Assisted Reproductive Technology
Difference Between Progestin Primed Ovarian Stimulation Protocol and Antagonist Protocol
compare the effectiveness and safety of the progestin primed ovarian stimulation (PPOS) protocol versus the antagonist protocol in hyper-responder patients scheduled for a freeze-all policy
- Trial name
- NCT06738602
- Volunteers
- 270 people
- Sponsor
- Assiut University
Infertility (IVF Patients), Infertility Assisted Reproductive Technology
ReceptIVFity & Immunology in ART
The goal of this clinical non-invasive observational pilot study is to improve the prediction of pregnancy success after In Vitro Fertilisation (IVF)/IVF -Intracytoplasmic Sperm Injection (ICSI) treatment by examining the vaginal…
- Trial name
- R-IMinART (NCT06709976)
- Testing
- Vaginal microbiome swab, Menstrual Blood Collection via Menstrual Cup
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
In Vitro Fertilization, Infertility Assisted Reproductive Technology
Assessment of Reproductive Outcomes in Non-Male Factor Infertility Patients: Conventional in Vitro Fertilisation Versus Intracytoplasmic Sperm Injection
The aim of this clinical trial is to evaluate the efficiency of two fertilization techniques used in Assisted Reproduction: conventional In Vitro fertilization (cIVF) and Intracytoplasmic Sperm Injection (ICSI), in terms of…
- Trial name
- NCT06670586
- Testing
- conventional in vitro fertilization, intracytoplasmic sperm injection (ICSI)
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Maria Dolores Cuquerella Fernandez-Vazquez
Infertility Assisted Reproductive Technology
Artificial Shrinkage of Fresh Blastocysts
The aim of the study is to determine if collapsing an embryo (or making it fold compactly by taking away its fluid) before the transfer in the uterine cavity improves pregnancy rates in assisted reproductive technology (ART).
- Trial name
- BlastoCollapse (NCT02988544)
- Testing
- Artificial shrinkage
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Assisted Reproductive Technology, Freezing/Thawing Procedure
Study of the Impact of Freezing-thawing Procedures and the Prolonged Culture of Embryos on Epigenetic Regulation in Humans
For this project, 4 groups of 38 infants have been created so as to evaluate the impact of Assisted-Reproduction Technology (ART) and more particularly the two procedures classically used in ART: the freezing/thawing of embryos…
- Conditions
- Assisted Reproductive Technology, Freezing/Thawing Procedure, Prolonged Culture Procedure
- Trial name
- NCT02171884
- Testing
- Sample of cord blood, Sample of placenta
- Where
- 2 sites in France
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Children Born After Assisted Reproductive Technologies, Health Status
Health Status of Children Born After Assisted Reproductive Technologies
The goal of this observational study is to study the features of psychophysical development and the morbidity patterns of children born after assisted pregnancy, and to identify the connection with the health status of mothers…
- Conditions
- Children Born After Assisted Reproductive Technologies, Health Status, Child Development
- Trial name
- NCT06094998
- Testing
- hemogram examination
- Where
- Kazakhstan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Kazakhstan's Medical University "KSPH"
Assisted Reproductive Technology
Progesterone Supplementation on Women Having Low Progesterone Levels on Transfer Day
The main objective of this study is to compare clinical pregnancy rates between two groups of women who have progesterone levels below 10 ng/mL on the day of frozen embryo transfer: group 1 (vaginal micronized progesterone…
- Trial name
- NCT04897269
- Testing
- Progesterone supplementation
- Where
- Vietnam
- Volunteers
- 824 people, healthy volunteers welcome
- Sponsor
- Tu Du Hospital
Assisted Reproductive Technology, Controlled Ovarian Hyperstimulation
Efficacy and Safety of BG2109 During Controlled Ovarian Hyperstimulation in Female Subjects Undergoing ART Procedures
To explore the optimal effective daily dose of BG2109 to suppress premature luteinizing hormone (LH) surge during COH in female subjects undergoing ART procedures.
- Trial name
- NCT05738382
- Testing
- BG2109, Cetrorelix
- Where
- 10 sites in China
- Volunteers
- 240 people
- Sponsor
- Bio Genuine (Shanghai) Biotech Co., Ltd.
Assisted Reproductive Technology
Oocyte Activation: Revised or Initial AGT Technique, Which is Better?! A Sibling-oocytes-split Design
This study will be conducted to compare two different Assisted Gamete treatment (AGT) with oocyte-sibling-split design control group : AGT- initial protocol for activating oocytes by culturing oocytes in calcium ionophore after…
- Trial name
- NCT05113238
- Testing
- Assisted gamete activation
- Where
- Egypt
- Volunteers
- 222 people
- Sponsor
- Royal Fertility Center, Egypt
Assisted Reproductive Technology, Infertility
Sperm Micro-swim up Technique; Process and Select in the Same Dish: a Sibling-oocyte-split Design
A sibling-Oocyte-split design will be conducted on oocytes before denudation and divided into two groups : control group (MII oocytes will be injected using sperm processed by Density gradient method) and sample group ( MII…
- Trial name
- NCT05113225
- Testing
- Micro-swim up technique
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Royal Fertility Center, Egypt
Assisted Reproductive Technology, Infertility
Construction of CITIC Xiangya Assisted Reproduction Data Repository
Human Assisted Reproductive Technology (ART) has become a very effective and nearly irreplaceable clinical treatment for infertility, helping millions of women achieve fertility.
- Trial name
- CXARDR (NCT05404464)
- Testing
- Different baseline characteristics and clinical management
- Volunteers
- 119,590 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Fertility Disorders, Assisted Reproductive Technology
The Clinical Cohort Study of Reproductive Health
The study will conduct a multicenter prospective clinical cohort study to collect comprehensive health information and essential specimens from pre-pregnancy to postpartum offspring development.
- Conditions
- Fertility Disorders, Assisted Reproductive Technology, Offspring Health
- Trial name
- NCT05164029
- Testing
- Completion questionnaires/providing biological samples
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Assisted Reproductive Techniques, Reproductive Technology, Assisted
PERgoveriS In Stratified Treatment for Assisted Reproductive Technique
This is a multicenter, multi-national, randomized, open-label comparative trial. After screening, the subjects will start down-regulation treatment on Day 21-22 of the cycle.
- Trial name
- PERSIST (NCT01297465)
- Testing
- Gonal-f®, Pergoveris®, Recombinant human chorionic gonadotropin (r-hCG)
- Where
- 23 sites in Denmark, Finland and 9 more
- Volunteers
- 202 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility, Assisted Reproductive Technology
Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?
Prospective, open, randomized, parallel, two-arm trial to compare the clinical pregnancy rate between most commonly used two embryo transfer techniques: trial followed by transfer technique and afterloading technique
- Conditions
- Infertility, Assisted Reproductive Technology, IVF
- Trial name
- NCT03756857
- Testing
- Afterload Transfer, Trial followed by transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Acibadem Kadiköy Hospital
Adenomyosis, Assisted Reproductive Technology
Low Molecular Weight Heparin on the Adenomyosis Patients'IVF-ET Outcome
In assisted reproductive technology, adenomyosis patients are characterized by lower clinical pregnancy rate, lower implantation rate and higher abortion rate.
- Trial name
- NCT04741295
- Testing
- Low molecular weight heparin
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Nanjing University
Sterility, Female, Reproductive Technology, Assisted
Prothrombotic Biomarkers and Ovarian Stimulation
The aim of this study is to assess the impact of different protocols used for ovarian stimulation during in vitro fertilization procedures (IVF) on prothrombotic biomarkers (blood coagulation markers associated with…
- Trial name
- HEMOSTIM (NCT04188444)
- Testing
- Blood test
- Where
- 2 sites in Switzerland
- Volunteers
- 65 people
- Sponsor
- University Hospital, Geneva
Assisted Reproductive Technology, Antibiotic Prophylaxis
Prophylactic Antibiotics Prior to Embryo Transfer (PAPET): RCT
The objective of this study is to determine the impact on clinical pregnancy rate of withholding routine prophylactic antibiotic therapy during IVF.
- Conditions
- Assisted Reproductive Technology, Antibiotic Prophylaxis, Embryo Transfer
- Trial name
- PAPET (NCT03386227)
- Testing
- Withholding antibiotic prophylaxis
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine