Clinical trials: Associated Conditions
Vasomotor Symptoms Associated With Menopause
Herbal Alternatives for Menopause Symptoms (HALT Study)
Surveys indicate that 25 to 33% of women have moderate to severe menopausal symptoms including hot flashes, night sweats, and disturbed sleep.
- Trial name
- NCT00169299
- Testing
- Black cohosh, Multibotanical preparation, Multibotanical preparation + dietary soy counseling
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Lipodystrophy Syndrome, HIV, Sarcopenia
Detraining in People Living With HIV/AIDS
The goal of this study was to evaluate the effect of detraining in the components of physical aptitude of people living with HIV/Aids (PVHA).
- Trial name
- PVHA (NCT03075332)
- Testing
- combined training
- Where
- 2 sites in Brazil
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Anal Fistula
Treatment of Complex Anal Fistulas Using Centrifuged Adipose Tissue Containing Progenitor Cells
In the treatment of complex anal fistulas transplant of freshly collected autologous adipose tissue mechanically fragmented or centrifuged adipose tissue (CAT) might be an alternative to in vitro expanded autologous or allogeneic…
- Trial name
- CAT (NCT04326907)
- Testing
- Autologous centrifuged adipose tissue (CAT) injection after anal fistulectomy
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Hyperekplexia
Effects of Mutations of the Glycine Gene Associated With Hyperekplexia on Central Pain Processing
Mutations in genes affecting pain transmission start to be known, the investigators are investigating a mutation in a glycine channel, which has an influence on pain modulation.
- Trial name
- NCT01476514
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Dystonia
Brain Function in Focal Dystonia
Objectives The main objectives of this proposal are (1) to characterize motor learning abnormalities in patients with focal dystonia; (2) to show, using transcranial magnetic stimulation, that this abnormal motor learning went…
- Trial name
- NCT00102999
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pulmonary Fibrosis, Rheumatoid Arthritis
Specimen Collection for Individuals With Lung Disease Associated With Rheumatoid Arthritis
Pulmonary fibrosis (PF) is a condition in which the lungs of a patient become scarred and fibrous. It has been known to occur in as many as 40% of patients diagnosed with rheumatoid arthritis (RA).
- Trial name
- NCT00001884
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Motion Sickness
Nasal Gel Under Military Operational Conditions for the Prevention of Nausea Associated With Motion Sickness
This multi-site Phase 3 clinical trial is a randomized, double-blind, placebo-controlled and open label active-controlled study to identify the safety and efficacy of a repeated-dose regimen of DPI-386 nasal gel (intranasal…
- Trial name
- NCT04272255
- Testing
- scopolamine HBr, Transdermal Scopolamine
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Healthy
Postprandial Effects of Mixed Herbs and Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects
This study aims to investigate the effect of mixed of herbs and spices on gene expression of pathways associated with glucose homeostasis, oxidative stress, inflammation and its interrelation with circulating miRNA, in the…
- Trial name
- NCT02931643
- Testing
- High fat challenge breakfast, High fat challenge breakfast with mixed-spices
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lund University
Catheter Related Infections, Short Bowel Syndrome
Trial of 70% Ethanol Versus Heparin to Reduce the Rate of Central Line Infections in Children With Short Bowel Syndrome
This study is designed to determine if the use of 70% ethanol lock solution in central lines decreases the rate of central line infections in children with short bowel syndrome.
- Trial name
- NCT01263574
- Testing
- 70% ethanol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Colonoscopy, Polyp of Colon
Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used
This is a study to compare two different, but normally, used methods of colonoscopy in patients that require a routine or repeat colonoscopy.
- Trial name
- ASGE (NCT03566615)
- Testing
- CAP-straight, CAP-daisy, water
- Where
- 7 sites in United States, China and 2 more
- Volunteers
- 1,630 people, healthy volunteers welcome
- Sponsor
- VA Greater Los Angeles Healthcare System
Pelvic Girdle Pain, Pubic Symphysis Diastasis
Pelvic Girdle Pain Early Postpartum: Underlying Condition and Associated Factors
Background: Pregnancy-related pelvic girdle pain (PGP) can appear during pregnancy, directly after labour or can be delayed to 3 weeks postpartum.
- Conditions
- Pelvic Girdle Pain, Pubic Symphysis Diastasis, Diastasis Recti
- Trial name
- NCT03835650
- Where
- Poland
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Influenza Vaccine in Preventing Flu in Patients Who Have Undergone Stem Cell Transplant and in Healthy Volunteers
RATIONALE: The influenza vaccine may help prevent flu in patients who have undergone stem cell transplant. PURPOSE: This clinical trial is studying how well the influenza vaccine works in preventing flu in patients who have…
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00952185
- Testing
- cytology specimen collection procedure, fluorescent antibody technique, assessment of therapy complications
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Nutrition, Obesity and Overweight
The Causal Role of Ketone Bodies in Obesity-associated Disease Prevention - Combining Genetic Epidemiology With a Randomised Trial to Infer Causality
Excess weight increases the risk of several diseases including cardiovascular disease, type 2 diabetes, kidney disease and various cancers.
- Trial name
- KETO-GENETIC (NCT06668168)
- Testing
- Ketone Monoester (KE), Ketogenic diet
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Bath
Dementia
Placebo-Controlled Crossover Study to Evaluate Donepezil and MK-3134 for Reversal of Cognitive Impairment Associated With Scopolamine Administration (3134-005)(COMPLETED)
The drug, scopolamine, can result in short-term impairments of cognitive function, attention, and memory that resemble those seen in aging and Alzheimer's disease.
- Trial name
- NCT01181310
- Testing
- C: MK-3134 25 mg + Scopolamine 0.5 mg, D: Donepezil 10 mg + Scopolamine 0.5 mg, E: Combo: Donepezil 10 mg + MK-3134 25 mg + Scopolamine 0.5 mg
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity
Effect of Ketone Esters on Liver Fat Content and Metabolic Function
The goal of this clinical trial is to determine whether ingestion of a ketone ester drink helps improve liver health and blood glucose control.
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity, Overweight (BMI > 25)
- Trial name
- JV (NCT07097506)
- Testing
- bis-octanoyl (R)-1,3-butanediol (C8 ketone di-ester)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Graves Disease, Graves Ophthalmopathy
Exploring Immunological Markers Associated With Mental Fatigue in Graves' Disease
Mental fatigue occurs in many diseases and the reasons are mostly unknown. The investigators hypothesize that remaining mental fatigue after restored hyperthyroidism in Graves' disease is an autoimmune complication.
- Conditions
- Graves Disease, Graves Ophthalmopathy, Mental Fatigue, Autoimmune Diseases
- Trial name
- NCT05678374
- Where
- Sweden
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Healthy, Pulmonary Fibrosis
Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis
Pulmonary fibrosis (PF) is a condition in which the lungs of a patient become scarred and fibrous. It has been known to occur in as many as 40% of patients diagnosed with rheumatoid arthritis (RA).
- Conditions
- Healthy, Pulmonary Fibrosis, Rheumatoid Arthritis
- Trial name
- NCT00001885
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Injection Site Irritation
The Prevention of Pain Associated With Rocuronium Injection
The purpose of this study is to determine whether efficacy of different doses of lidocain and acetaminophen for the prevention of rocuronium injection pain and frequency of withdrawal movements during the general anesthesia…
- Trial name
- NCT02524743
- Testing
- acetaminophen, Lidocaine
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Hypertension, Obesity
Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
The purpose of this study is to understand how the nervous system communicates to blood vessels to increase blood pressure during stress.
- Trial name
- OB-HTN (NCT04838678)
- Testing
- Neuropeptide Y
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center