Clinical trials: Asthma, Bronchial
Asthma
Measuring Exhaled Nitric Oxide (eNO) Using the Apieron INSIGHT System and the Aerocrine NIOX System
Collection of quantitative data to demonstrate the accuracy (bias) and precision (repeatability) of the Apieron INSIGHT(tm) eNO Breath System as compared to the FDA cleared NIOX eNO Breath System when testing is performed by…
- Trial name
- NCT00739531
- Testing
- Exhaled nitric oxide (eNO)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Apieron
Asthma, Covid19
COVID-19 Infection and Epithelial Cell Markers
To assess if TSLP expression by airway epithelial cells following COVID-19 infection regulates viral load and disease severity.
- Trial name
- NCT04787588
- Where
- Canada
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- McMaster University
Asthma
Use of Text Messages to Improve Care For Children Following an ED Visit for Asthma
BACKGROUND Asthma is a prevalent and troublesome pediatric condition. In 2013, Emergency Department (ED) providers treated over 3,500 cases of asthma-related complaints at Children's Hospitals and Clinics of Minnesota.
- Trial name
- NCT02436070
- Testing
- Targeted text messages, General text messages
- Where
- 2 sites in United States
- Volunteers
- 195 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Asthma
Airway Smooth Muscle and Asthma Severity
Our hypothesis is that the severity of asthma is determined by the way in which airway smooth muscle cells grow and release inflammatory mediators.
- Trial name
- NCT00779870
- Testing
- bronchoscopy
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pulmonary Rehabilitation, Asthma
Efficiency of Home-Based Pulmonary Rehabilitation in Adults With Asthma
Asthma is a serious global health problem affecting people of all ages in every country in the world. Despite the presence of effective medications, many studies have reported poor asthma control in patients.
- Conditions
- Pulmonary Rehabilitation, Asthma, Home-based Pulmonary Rehabilitation
- Trial name
- NCT04088669
- Testing
- Home-based Pulmonary Rehabilitation, Education and Recommendations
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Pulmonary Disease, Chronic Obstructive
Osteoprotegerin (OPG) in Induced Chronic Obstructive Pulmonary Disease (COPD) Sputum
Evaluation of OPG level as disease markers has also been reported. It has been showed that patients with coronary artery disease had higher serum OPG levels than healthy volunteers.
- Trial name
- NCT00655954
- Testing
- Induced sputum
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma in Children
Pulmonary Rehabilitation Combined With Speleotherapy in Children With Bronchial Asthma
The goal of this retrospective study is to learn about the effects of rehabilitation and treatment stays combined with speleotherapy in children with asthma.
- Trial name
- NCT06557824
- Testing
- speleotherapeutic intervention
- Where
- Poland
- Volunteers
- 415 people
- Sponsor
- University School of Physical Education, Krakow, Poland
Asthma
Cardiovascular Diseases in Elderly Asthma
This study is a cross-sectional study to evaluate the relationship between coronary calcium score and clinical parameters of asthma such as onset of disease, lung function parameter and airway inflammation parameter (sputum…
- Trial name
- NCT03509259
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Asthma
A 12-Week Study in Asthmatic Children Ages 6 to <12 Years, Investigating the Efficacy and Safety of Symbicort pMDI 80/2.25 μg and Symbicort pMDI 80/4.5 μg, Compared With Budesonide pMDI 80 μg
The purpose is to investigate the Efficacy and Safety of Symbicort pMDI 80/2.25 μg and Symbicort pMDI 80/4.5 μg, Compared with Budesonide pMDI 80 μg, 2 Actuations Twice Daily, in Children Ages 6 to <12 Years with Asthma during 12…
- Trial name
- CHASE 3 (NCT02091986)
- Testing
- Symbicort pMDI, Budesonide pMDI
- Where
- 70 sites in United States, Mexico and 2 more
- Volunteers
- 882 people
- Sponsor
- AstraZeneca
Asthma
Indoor Woodsmoke PM and Asthma
Although particulate matter (PM) exposures have been linked with poor respiratory health outcomes, most of these studies have focused on airsheds with urban and industrial sources of PM2.5.
- Trial name
- ARTIS (NCT00807183)
- Testing
- woodstove, inactive air filter, Active air filter
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Bronchial Asthma
A Study to Evaluate the Efficacy and Safety of HSK31858 Tablets in Patients with Bronchial Asthma
This is a phase II, randomised, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of HSK31858 in patients with bronchial asthma
- Trial name
- NCT06637254
- Testing
- HSK31858
- Where
- China
- Volunteers
- 219 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Allergy, Respiratory Disease
Impact of AIT on Allergic Rhinitis and Asthma
The study will assess the effectiveness of AIT treatment in real clinical practice in Germany.
- Trial name
- NCT04125888
- Testing
- Allergy immunotherapy (AIT)
- Where
- Denmark
- Volunteers
- 92,048 people
- Sponsor
- ALK-Abelló A/S
Asthma
Asthma Symptom Based Adjustment of Inhaled Steroid Therapy in African American Children
African American (AA) children carry a disproportionate burden of mortality and morbidity in asthma. A major contributor to racial disparity in asthma is lack of adherence to guideline-recommended use of daily inhaled…
- Trial name
- ASIST (NCT02298205)
- Testing
- Asthma controller medication (Beclomethasone) adjustment strategy, Provider-based adjustment
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Washington University School of Medicine
Asthma
Efficacy and Safety of Ciclesonide (CIC) Administered Twice Daily in Pediatric Patients With Asthma.
Primary objective: To demonstrate the efficacy of ciclesonide, compared to placebo, at 80 μg twice daily (BID) or 40 μg BID for 12 weeks in patients with persistent asthma.
- Trial name
- NCT00392288
- Testing
- Ciclesonide
- Where
- 6 sites in United States, Hungary and 4 more
- Volunteers
- 528 people
- Sponsor
- AstraZeneca
Asthma
Immune Response to Pneumococcal Polysaccharide Vaccine (23-valent) Predicts Asthma Status and Outcomes in Late Adolescents With Asthma
Advisory Committee for Immunization Practices (ACIP) from the Centers for Disease Control (CDC) recommends that children (6-18 years) and adults (≥19 years old) with chronic lung condition such as asthma or cigarette smoking be…
- Trial name
- NCT02719379
- Testing
- Pneumonococcal Polysaccharide Vaccine 23-valent (PPSV-23)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rohit Divekar
Asthma Childhood
Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination
The overall goal of this research study is to test the effectiveness of a multifaceted and multi-level prompting intervention in a real world urban primary care office setting on improving provider-delivered guideline-based…
- Trial name
- PRAGMATIC (NCT03066596)
- Testing
- eMPI
- Where
- United States
- Volunteers
- 530 people
- Sponsor
- Montefiore Medical Center
Asthma
The Electronic Asthma Management System
This study is an extension of a pilot study in which investigators developed and tested a computerized tool to help physicians to determine if their patients' asthma is well controlled, advise them on medication changes required…
- Trial name
- eAMS (NCT03193242)
- Testing
- Electronic Asthma Management System: eAMS
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Unity Health Toronto
Severe Asthma
Evaluate the Pharmacokinetics of BAT2606 Injection in Healthy Chinese Male Subjects
To evaluate the pharmacokinetics, safety and immunogenicity of BAT2606 in healthy China male subjects.
- Trial name
- NCT05576454
- Testing
- Mepolizumab Injection (BAT2606 Injection), Mepolizumab Injection (EU-licensed Nucala), Mepolizumab Injection (US-licensed Nucala)
- Where
- China
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Bio-Thera Solutions
Influenza Like Illness, Asthma
How Does the Clinical Tool 'What's Going Around' Affect Clinical Practice
Previous work has shown that the epidemiological context of a patient's presentation can provide important information for clinicians to aid in diagnosis and treatment.
- Conditions
- Influenza Like Illness, Asthma, Group A Streptococcal Infection, Pertussis
- Trial name
- WGA (NCT01979588)
- Testing
- What's Going Around tool, Control
- Where
- United States
- Volunteers
- 206,703 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Asthma
VENTURI (VENTilation Using Respiratory Imaging)
The purpose of the study is to enroll participants with uncontrolled asthma to evaluate the large and small airways and drug delivery utilizing two study drugs: Beclometasone dipropionate/Formoterol fumarate…
- Trial name
- VENTURI (NCT07282886)
- Testing
- Beclomethasone Dipropionate/Formoterol Fumarate/Glycopyrrolate pMDI, Fluticasone Furoate/Umeclidinium/Vilanterol 100 MCG/1 ACTUATION-62.5 MCG/1 ACTUATION-25 MCG/1 ACTUATION Inhalation Powder
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham