Clinical trials: Asthma, completed
Perennial Allergic Rhinoconjunctivitis, Allergic Asthma
Effect of an Allergen Vaccine in Patients With Allergic Rhino-Conjunctivitis and Asthma Due to House Dust Mite Allergy
The purpose of the study is to test the safety, tolerability, immunogenicity and clinical efficacy of the combination treatment AllQbG10 in patients with rhino-conjunctivitis and asthma due to house dust mite allergy in a…
- Trial name
- NCT00652223
- Testing
- CYT005-AllQbG10
- Where
- Switzerland
- Volunteers
- 21 people
- Sponsor
- Cytos Biotechnology AG
Asthma
Investigating The Pharmacokinetics Of An Inhaled Dose Of A New Corticosteroid In Patients With Impaired Liver Function
The proposed study is designed to investigate the pharmacokinetics, pharmacodynamics (as measured by serum cortisol) and safety of GW685698X in subjects with moderate hepatic impairment and in healthy subjects following a single…
- Trial name
- NCT00419237
- Testing
- GW685698X
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma
Bioequivalence Study of Methacholine for Inhalation (pharmacodynamics)
This trial was divided into two parts. This is the scecond part. The second part is the pharmacodynamic equivalence study of patients, which is a single-dose, randomized, open, two-cycle, two-sequence crossover design, and plans…
- Trial name
- NCT06725641
- Testing
- Test preparation：Methylcholine chloroacetate for inhalation, Reference preparation：Methylcholine chloroacetate for inhalation（Provocholine）
- Where
- China
- Volunteers
- 40 people
- Sponsor
- China-Japan Friendship Hospital
Asthma
Beta Blockers for the Treatment of Asthma
Current asthma medicines include inhalers. A common inhaler used in asthma is called a beta-agonist (for example salbutamol). They improve asthma symptoms by stimulating areas in the human airway resulting in widening of the…
- Trial name
- NCT01074853
- Testing
- propranolol
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Dundee
Asthma
Safety and Tolerability Study of Levalbuterol HFA and Racemic Albuterol HFA in Pediatrics Subjects With Asthma
The purpose of this study is to compare the safety and tolerability of levalbuterol HFA metered dose inhaler (MDI) versus racemic albuterol HFA MDI in pediatric subjects 4-11 years of age with asthma
- Trial name
- NCT00684866
- Testing
- Levalbuterol HFA MDI followed by Racemic albuterol HFA MDI, Racemic Albuterol followed by levalbuterol HFA MDI
- Where
- 11 sites in United States
- Volunteers
- 31 people
- Sponsor
- Sumitomo Pharma America, Inc.
Asthma in Children, Wheezing
Secondhand Smoking in Asthmatic Children
This study will investigate the interaction between GSTP1 / TNFa polymorphisms and passive smoking in children with asthma/wheezing. Contemporary second hand-smoke exposure will be confirmed by laboratory testing.
- Trial name
- NCT03099902
- Testing
- Lung function, White blood cell DNA extraction, Urinary testing
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Asthma, Chronic Obstructive Pulmonary Disease
Efficacy of Inhalation Technique Training.
Pharmacologic treatment of asthma and COPD is based mainly on inhalations. The aim of the study is to determine if short training of inhalation technique in patients with obstructive diseases may influence the course of asthma…
- Trial name
- NCT02131454
- Testing
- Inhalation technique training
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
Asthma
Assessment of Bronchial Thickness Using MRI in Asthma
Bronchial remodeling is a major pathological feature of asthma. Non-invasive assessment of this bronchial remodeling is a crucial issue for asthma patients' follow-up.
- Trial name
- ASTHMAGRI (NCT03089346)
- Testing
- Magnetic Resonance Imaging (MRI) with Ultrashort Echo Time (UTE), Computed tomography (CT)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bordeaux
Asthma
Investigation of Lung Ventilation Inhomogeneity in Pediatric Asthma
The primary objective of this study is to determine if well-controlled asthmatic patients followed in subspecialty asthma clinics between the ages of 3 - 18 years can be distinguished from healthy controls using lung clearance…
- Trial name
- NCT01095354
- Testing
- Sodium Chloride Inhalation
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Asthma
Fluticasone-Vilanterol Once Daily Dose for the Treatment of Mild Asthma in Adults
Investigators will test the superiority of Superiority Trial of Fluticasone-Vilanterol as needed in mild asthma compared to standard of care
- Trial name
- NCT04265105
- Testing
- fluticasone-vilanterol, Standard Preparation
- Where
- Bahrain
- Volunteers
- 18 people
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
Asthma, Rhinitis
Oral Bacteria and Allergic Disease in Children
This study will see if bacteria differ between children who have allergies or asthma and children who do not have allergies or asthma. Previous research suggests that some bacteria may protect against allergies and asthma.
- Conditions
- Asthma, Rhinitis, Eczema, Respiratory Sounds
- Trial name
- NCT00438646
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Bioequivalence Study of Budesonide/Formoterol Inhalation Powder in Healthy Participants
The goal of this study is to learn if a new formulation of Budesonide/Formoterol Inhalation Powder (160μg/4.5μg), manufactured by Shanghai New Huanghe Pharmaceutical Co., Ltd., works the same as the already approved reference…
- Trial name
- BF-BE (NCT07804303)
- Testing
- Budesonide and Formoterol Fumarate Powder for Inhalation (II) (Test), Budesonide and Formoterol Fumarate Powder for Inhalation (II) (Reference)
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Xin Huanghe Pharmaceutical Co., Ltd.
Premature Birth, Bronchopulmonary Dysplasia
Assessment of Lung Structure and Function of Infants Born Prematurely
The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.
- Conditions
- Premature Birth, Bronchopulmonary Dysplasia, Asthma
- Trial name
- NCT00422305
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pulmonary Disease, Chronic Obstructive
Characterisation of Healthy Volunteers, Asthma and Chronic Obstructive Pulmonary Disease Patients for Inhalation Profile, Pharyngometry, Spirometric Indices and Lung Morphometry
This is a clinical study, with no investigational product, to characterise the inhalation profiles of healthy volunteers, volunteers with mild, moderate and severe Asthma and volunteers with mild, moderate and severe Chronic…
- Trial name
- NCT01345266
- Testing
- Inhalation Profiling
- Where
- 2 sites in Belgium
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma
Effects of CPAP in Severe Therapy-resistant Asthma
The purpose of this study is to verify the effects of continuous positive airway pressure (CPAP) on exercise capacity of children and adolescents with severe therapy-resistant asthma (STRA).
- Trial name
- CPAP-STRA (NCT03215303)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Brazil
- Volunteers
- 13 people
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Asthma
Triple in Asthma Dose Finding
Primary objective The primary objective was to evaluate the efficacy of a free combination of CHF 5259 at 3 dose levels plus Foster® 100/6 μg in a pMDI by comparison with Foster® 100/6 μg in terms of forced expiratory volume in…
- Trial name
- Triskel (NCT02127866)
- Testing
- CHF 5259 plus Foster 100/6 µg, Foster 100/6 µg (four puffs BID)
- Where
- 44 sites in Bulgaria, Germany and 4 more
- Volunteers
- 211 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma, Obesity
Can Diet- and Exercise-Induced Weight Loss Improve Asthma Control in Adults?
The goal of the study is to investigate the efficacy of an evidence-based weight loss intervention, on a background of quality health care, on asthma control among obese adults.
- Trial name
- NCT00901095
- Testing
- Lifestyle intervention
- Where
- 8 sites in United States
- Volunteers
- 330 people
- Sponsor
- Palo Alto Medical Foundation
Asthma
RSPR-007 Mannitol Challenge Trial
This is a double-blind, randomised, placebo-controlled, cross-over, Phase 2 trial evaluating two doses (a low and a high) of CRD007 for the treatment of asthmatic trial subjects with a positive asthma test (mannitol challenge)…
- Trial name
- NCT02609334
- Testing
- CRD007
- Where
- 2 sites in Denmark
- Volunteers
- 24 people
- Sponsor
- RSPR Pharma AB
Airway Inflammation, Asthma
A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults
Purpose: To determine the efficacy of 1400 mg gamma tocopherol-enriched supplement for mitigating inhaled wood smoke particle-induced airway inflammation in healthy adults with no more than mild asthma.
- Trial name
- SmokeyT (NCT03444298)
- Testing
- Gamma Tocopherol
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Respiratory Syncytial Virus Bronchiolitis
Respiratory Syncytial Virus (RSV) Follow-Up Study (MK-0476-374)
This is a prospective, multicenter, observational study in participants who completed the 24-week, placebo-controlled MK-0476 Protocol 272 (NCT00076973) study of montelukast in the treatment of respiratory symptoms subsequent to…
- Trial name
- NCT01140048
- Volunteers
- 343 people
- Sponsor
- Organon and Co
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