Clinical trials: Asthma (Diagnosis)
Pulmonary Disease, Chronic Obstructive, Asthma
Handling Inhalers - Technique Error Comparison (HI-TEC)
Randomised, cross sectional, observational study evaluating inhaler device critical errors (errors that could affect dose delivery to the lungs) for the Pulmojet inhaler compared to Diskus or Turbuhaler in asthma and COPD…
- Trial name
- HI-TEC (NCT01794390)
- Where
- United Kingdom
- Volunteers
- 431 people
- Sponsor
- Research in Real-Life Ltd
Asthma Chronic
Breathing Exercises Effect on Lung Functions and Chest Expansion in Asthmatics
The goal for this clinical trial was to compare the effectiveness of Diaphragmatic Breathing and Pursed-Lip Expiration Exercises in improving lung functions {the Peak Expiratory Flow Rate (PEFR) and Forced Expiratory Volume in 1…
- Trial name
- DB&PLB/PFT (NCT07477080)
- Testing
- diaphragmatic breathing exercise, pursed lip breathing exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Asthma
Investigation of the 24 Hour Forced Expiratory Flow in 1 Second (FEV1) Profile of a Single Dose of Indacaterol/Mometasone Delivered Via the TWISTHALER® Device in Adult Patients With Persistent Asthma
This study is designed to provide data about the 24 hours FEV1 profile, safety and tolerability of indacaterol/mometasone TWISTHALER device compared to placebo and using fluticasone/salmeterol as an active control.
- Trial name
- NCT00557440
- Testing
- fluticasone propionate/salmeterol, indacaterol maleate / mometasone furoate
- Where
- 6 sites in Belgium, Germany
- Volunteers
- 37 people
- Sponsor
- Novartis
Other Preterm Infants, Vitamin D Deficiency
The Effect of Vitamin D Administration to Premature Infants on Vitamin D Status and Respiratory Morbidity
This trial objective is to assess whether doubling the daily intake of vitamin D improves serum vitamin D levels and serves as primary prevention of respiratory infections and asthma in premature infants.
- Conditions
- Other Preterm Infants, Vitamin D Deficiency, Bronchiolitis, Asthma
- Trial name
- NCT02404623
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Asthma
Safety and Efficacy Study of OC000459 Dosed Twice Daily for 28 Days in Asthmatic Subjects
The purpose of the study is to investigate the clinical effects of multiple (28 day) twice-daily doses of OC000459 in comparison to placebo on clinic lung function (FEV1) in mild to moderate asthmatics with an FEV1 of 60-80% of…
- Trial name
- NCT01057927
- Testing
- OC000459
- Where
- 16 sites in Russia
- Volunteers
- 132 people
- Sponsor
- Oxagen Ltd
Hypertension, Diabetes Mellitus, Type 2
Enhancing Community Health Through Patient Navigation, Advocacy and Social Support
Some patients who have multiple long-term health conditions have significant challenges accessing needed services despite available primary care and social services resources.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Chronic Kidney Diseases, Ischemic Heart Disease
- Trial name
- ENCOMPASS (NCT03077386)
- Testing
- ENCOMPASS Intervention
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- University of Calgary
Asthma
Regular Use Effect of Inhaled Ipratropium Bromide on Airway Responsiveness to Methacholine in Well-controlled Asthma
Study is looking at the development of tolerance to methacholine following regular use of ipratropium bromide in mild asthmatics.
- Trial name
- NCT04167280
- Testing
- Ipratropium Metered Dose Inhaler
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Saskatchewan
Asthma
To Assess the Pharmacokinetics, Safety and Tolerability of Abediterol Administered Once Daily for 9 Days, in Patients With Asthma on Inhaled Corticosteroids
A Phase 1 study to assess pharmacokinetics (PK) and safety of abediterol 5 μg dry powder inhaler (DPI) given once daily (QD) for 9 days, compared to placebo, in patients with asthma on inhaled corticosteroids (ICSs).
- Trial name
- NCT03273127
- Testing
- Abediterol
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- AstraZeneca
Severe Asthma
Patient Characteristics, Treatment Patterns and Outcomes of Patients With Severe Asthma Treated With Tezepelumab in the Real World; a Retrospective, Observational Medical Chart Review Conducted in UK Severe Asthma Centres
This is a retrospective, observational chart review that will include patients with severe asthma (SA) who have participated in the tezepelumab patient access programme (TPAP).
- Trial name
- TRAILBLAZE (NCT06455462)
- Testing
- Tezepelumab
- Where
- 6 sites in United Kingdom
- Volunteers
- 352 people
- Sponsor
- AstraZeneca
Asthma
The Additive Anti-inflammatory Effect of Simvastatin in Combination With Inhaled Corticosteroids in Asthma
We hypothesize that simvastatin in combination with ICS might have synergistic anti-inflammatory effects on airway inflammation in asthmatic patients
- Trial name
- NCT00792337
- Testing
- simvastatin, B1-6-12
- Where
- Thailand
- Volunteers
- 53 people
- Sponsor
- Mahidol University
Asthma, Chronic Obstructive Pulmonary Disease
Interpreting Respiratory Oscillometry in Adult Asthma and COPD: a Delphi Study
This is an international Delphi study to consolidate expert consensus on the use of respiratory oscillometry in the management of adult patients with asthma or chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT06313372
- Testing
- Respiratory oscillometry
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Scius Healthcare Solutions Pty Ltd
Obesity, Asthma
Intragastric Balloon in Obese Patients With Uncontrolled Asthma
The aim of this project is to study the effect of an intragastric balloon (IGB) on asthma control in obese patients. Obese patients with uncontrolled asthma will be recruited and randomly assigned to two intervention arms : an…
- Trial name
- BOA (NCT05364957)
- Testing
- Intragastric balloon device, Dietary, Exercise intervention
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Toulouse
Asthma
A Study of RO4989991 in Patients With Allergic Rhinitis
This multi-center, randomized, observer-blinded, placebo-controlled study will evaluate the safety and tolerability of subcutaneous doses of RO4989991 in patients with allergic rhinitis who are otherwise healthy.
- Trial name
- NCT01152619
- Testing
- RO4989991
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- Hoffmann-La Roche
Asthma
Airway Inflammation and Disease Burden in Asthmatic Smokers
Aim : To compare, among patients with an uncontrolled moderate to severe asthma, the blood eosinophil levels of smokers and non-smokers.
- Trial name
- NCT02833727
- Testing
- Smoking
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Université de Montréal
Asthma
Assessment of the Safety of ABT-308 in Healthy Volunteers and Subjects With Asthma
The primary purpose of this study is to determine the safety, tolerability and pharmacokinetics of ABT-308 in healthy volunteers and patients with mild to moderate controlled asthma.
- Trial name
- NCT00986037
- Testing
- ABT-308
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- AbbVie
Gastroesophageal Reflux, Asthma
Elucidation of Acid-Induced Pulmonary Inflammation
This study will evaluate how heartburn may lead to different types of inflammation in one's airways. Additionally, the study will determine whether aggressive treatment of heartburn results in improvement in both symptoms of…
- Trial name
- NCT00361972
- Testing
- lansoprazole
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Utah
Asthma
To Investigate the Effects of Altering the Time of Day of Dosing (Morning or Evening) With Fluticasone Furoate 100 Micrograms Once Daily Administered Via a Dry Powder Inhaler in Subjects With Asthma
This study will investigate the effects of altering the time of day of dosing (morning or evening) with Fluticasone Furoate 100 (FF 100) micrograms (mcg) once daily administered via a dry powder inhaler (DPI) in subjects with…
- Trial name
- NCT01808339
- Testing
- Fluticasone Furoate (FF)
- Where
- Australia
- Volunteers
- 28 people
- Sponsor
- GlaxoSmithKline
Asthma
Guidance of Patients With Asthma During Preparation and During Expedition to the Aconcagua Mountain
A selection of asthma patients were followed during preparation to climb the Aconcagua mountain. The primary goal of this follow up was to optimize patients' asthma status.
- Trial name
- NCT01760928
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Asthma Acute, Exacerbation of Allergic Asthma
Nebulized Ketamine for Severe Asthma Attacks in Children
This is a double-blinded, randomised, placebo-controlled trial enrolling 60 children aged 1 to 13 years with severe asthma exacerbation. All participants will receive standard therapy.
- Trial name
- NCT07728851
- Testing
- Ketamine (1 mg/kg)
- Where
- Oman
- Volunteers
- 60 people
- Sponsor
- Sultan Qaboos University
Bronchial Asthma
Safety, Tolerability, and Pharmacokinetics of PA9159 Inhalation Aerosol in Healthy Adult Subjects
PA9159 is a highly potent novel corticosteroid. The purpose of this study is to exam the safety, tolerability, and pharmacokinetics of single and repeat dosing of Inhalation aerosol PA9159, to establish maximum tolerated dose in…
- Trial name
- NCT06916273
- Testing
- PA9159 Inhalation aerosol, 60 μg one day treatment, PA9159 Inhalation aerosol, 120 μg one day treatment, PA9159 Inhalation aerosol, 240 μg one day treatment
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anhui Palo Alto Pharmaceuticals, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.