Clinical trials: Asthma Acute
Asthma, Aged
Effects of Multidisciplinary Interventions in Elderly Asthma Patients With Risk of Acute Exacerbation
We want to examine the effect of multidisciplinary interventions in asthma patients who had experienced acute exacerbation of asthma.
- Trial name
- NCT01843439
- Testing
- Magnesium, Education for asthma action plan, hot-lines for acute exacerbation of asthma
- Where
- South Korea
- Volunteers
- 360 people
- Sponsor
- Sang-Heon Cho
Asthma
Comparison of Breath-Enhanced and T-Piece Nebulizers in Children With Acute Asthma
This is a blinded observer randomized controlled trial comparing two nebulizer devices. The objective of this study is to evaluate the efficacy of two different nebulizers.
- Trial name
- NCT02566902
- Testing
- T-Piece Nebulizer, Breath-Enhanced Nebulizer, Albuterol
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Seton Healthcare Family
Asthma
Efficacy and Safety of Levalbuterol Versus Racemic Albuterol in Asthma
To investigate the Efficacy and Safety of Levalbuterol versus Racemic Albuterol in the Treatment of Acute Asthma.
- Trial name
- NCT00667407
- Testing
- Levalbuterol 1.25 mg, Racemic Albuterol Sulfate
- Where
- 28 sites in United States
- Volunteers
- 627 people
- Sponsor
- Sumitomo Pharma America, Inc.
Conditions, Infections
Analysis of the Virtual Acute Care at Home Experience
The purpose of this study is to examine the implementation, intervention effectiveness, and dissemination of a digital acute care delivery model for improving selected health outcomes in the Hospital at Home population.
- Conditions
- Conditions, Infections, Heart Failure, Renal and Urinary Disorders
- Trial name
- HaH (NCT05952999)
- Testing
- Digital Care Solution as supportive personalized care, Traditional Hospital Level Care
- Where
- United States
- Volunteers
- 9,654 people
- Sponsor
- OSF Healthcare System
ASTHMA
Measurement of Natriuretic Hormone Peptides in Exacerbation of Asthma
The investigators hypothesize that there is a statistically significant decrease of Natriuretic Hormone Peptides (NHPs) in subjects with asthma exacerbation compared to levels following treatment of an exacerbation of asthma.
- Trial name
- acute asthma (NCT01690793)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of South Florida
Bronchiolitis Acute, Lower Respiratory Tract and Lung Infections
Modern Technologies in Lower Respiratory Tract Infections in Children
Lower respiratory tract infections (LRTIs) are a significant cause of childhood morbidity and mortality globally, particularly in low-income countries.
- Conditions
- Bronchiolitis Acute, Lower Respiratory Tract and Lung Infections, Pediatric Lung Ultrasound, Tidal Volume
- Trial name
- MoT-LRTI (NCT07381790)
- Testing
- lung ultrasound, Tidal-flow volume loops
- Where
- 2 sites in Norway
- Volunteers
- 200 people
- Sponsor
- Helse Møre og Romsdal HF
Asthma
Study of Budesonide as an Addition to Standard Therapy in Adult Asthmatics in the Emergency Room.
To determine whether adding nebulized inhaled steroids to the standard care of acutely ill ED patients with refractory acute asthma helps improve forced expiratory volume at one second (FEV1) and decrease the need for…
- Trial name
- NCT00588406
- Testing
- Budesonide, albuterol, Ipratropium bromide
- Where
- 3 sites in United States
- Volunteers
- 95 people
- Sponsor
- Northwell Health
Asthma Exacerbation, Children
A Comparative Study of Adding Ipratropium to Salbutamol for the Treatment of Asthma Attack in Children
The goal of this clinical trial was to determine if adding ipratropium bromide to salbutamol improves asthma treatment in children.
- Trial name
- NCT06918418
- Testing
- Salbutamol (Ventolin®), salbutamol + ipratropium bromide nebules
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Acute Asthma
Acute Asthma Responsiveness and B2 Adrenergic Receptors Polymorphisms
The hypothesis to be tested is that acutely ill asthmatics who do not resolve their attacks following standard doses of albuterol and require admission to hospital have single nucleotide polymorphisms of their B2 adrenergic…
- Trial name
- NCT01016444
- Where
- United States
- Volunteers
- 311 people
- Sponsor
- MetroHealth Medical Center
Asthma, Heart Rate Fast
Acute Effect of Salbutamol on Heart Rate and Blood Pressure During Exercise in Patients With Moderate or Severe Asthma and Healthy Subjects
Contextualization: Exercise is a common triggers of bronchospasm in patients with asthma and healthy subjects. To prevent these symptoms frequently they have to use Short-Acting Beta2-Agonists.
- Trial name
- NCT03044938
- Testing
- salbutamol
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera
Respiratory Tract Infections
Procalcitonin Guided Antibiotic Use in Acute Respiratory Tract Infections (PARTI)-Study
Acute respiratory tract infections (ARTI) are among the most frequent reasons for seeking medical attention in primary care. Although from predominantly viral origin, ARTIs are the most important condition for the prescription of…
- Trial name
- NCT00099840
- Testing
- Procalcitonin guided antibiotic therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Asthma, Bronchial
Use of Montelukast to Treat Children With Mild to Moderate Acute Asthma
The primary objective of this study is to evaluate if children with acute asthma given a single dose of oral prednisolone with a subsequent daily five-day course of oral Montelukast will achieve a therapeutic failure rate at day…
- Trial name
- NCT00213252
- Testing
- Montelukast plus prednisolone, Prednisolone
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- The Hospital for Sick Children
Acute Exacerbation of Asthma
Dexamethasone Versus Prednisolone in Acute Exacerbation of Childhood Asthma
Because of insufficient local comparative data, this study was designed to determine the outcome of intravenous dexamethasone in contrast to oral prednisolone in acute exacerbation of asthmatic children.
- Trial name
- NCT07275593
- Testing
- Dexamethasone, Prednisolone
- Where
- Pakistan
- Volunteers
- 224 people
- Sponsor
- Muhammad Aamir Latif
Acute Asthma
Nebulized Budesonide Combined With Systemic Corticosteroid in Acute Severe Asthma
Our study is a prospective double-blind randomized study performed in the Emergency Department (ED). The objective of our study was to demonstrate the additive effect of high and repeated doses of inhaled budesonide combined with…
- Trial name
- NCT04016220
- Testing
- Budesonide, normal saline
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University of Monastir
Asthma
A Study to Evaluate the Acute Bronchodilator Effect of CHF1535 NEXThaler
The aim of the study is to demonstrate the non-inferiority in terms of acute bronchodilator effect between a single dose of CHF 1535 NEXThaler 200/6 µg and a single dose of CHF 1535 NEXThaler 100/6 µg at two dose levels in…
- Trial name
- NCT02148120
- Testing
- Beclometasone Dipropionate 100 µg + Formoterol Fumarate 6 µg, Beclometasone Dipropionate 200 µg + Formoterol Fumarate 6 µg
- Where
- 3 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Sickle Cell Disease, Anemia, Sickle Cell
Daily Vitamin D for Sickle-cell Respiratory Complications
This study aims to answer the question whether daily oral vitamin D supplementation can reduce the risk of respiratory or lung complications in children and adolescents with sickle cell disease.
- Conditions
- Sickle Cell Disease, Anemia, Sickle Cell, Anemia, Hemolytic, Congenital, Respiratory Tract Diseases
- Trial name
- ViDAS-2 (NCT04170348)
- Testing
- Daily oral vitamin D3, 3,333 IU, Monthly oral vitamin D3, 100,000 IU
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Columbia University
Asthma
TELICAST : Telithromycin in Acute Exacerbations of Asthma
Primary Objective: The primary objective is to evaluate the clinical efficacy of telithromycin versus placebo as a supplement to the usual standard of care during an acute exacerbation of asthma.
- Trial name
- NCT00273520
- Testing
- Telithromycin
- Sponsor
- Sanofi
Emergencies, Heart Failure
The Use of a Monitoring Device by General Practitioners During Out-of-hours Care
All calls that end up on the out-of-hours general practitioners' service (OHGPS), which contain a demand for an urgent home visit, are passed on to the on-call general practitioner (GP).
- Conditions
- Emergencies, Heart Failure, Pulmonary Embolism, Acute Exacerbation of Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05222711
- Testing
- Use of the PICO(TM) monitoring device
- Where
- Belgium
- Volunteers
- 866 people
- Sponsor
- KU Leuven
Asthma Acute
Use of Dupilumab in Asthma in Real-world Setting
The main objective of asthma pharmacological management in adults and teenagers is to maintain long-term control of the disease, including symptom relief, the prevention of exacerbations, the improvement of pulmonary function…
- Trial name
- DUPILUMAB (NCT07637292)
- Where
- France
- Volunteers
- 35,000 people
- Sponsor
- Hospices Civils de Lyon
Acute Viral Bronchiolitis
KL-6 Protein as a Biomarker of Lung Injury in Viral Bronchiolitis
Serum KL-6 protein has been described as a biomarker of epithelial lung injury in Respiratory Syncytial Virus bronchiolitis. The investigators can imagine that epithelial injury intensity has consequences on immediate and later…
- Trial name
- NCT01437956
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand